专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012044121A3 SYSTEM FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY 审中-公开
标题翻译：用于诊断AVELLINO CORNEAL DYSTROPHY的系统
公开(公告)号：WO2012044121A3
公开(公告)日：2012-06-07
申请号：PCT/KR2011007272
申请日：2011-09-30
申请人： AVELLINO CO LTD , LEE GENE , YUN JUNG KUK
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： A61B3/18
CPC分类号： C12Q1/686 , C12Q1/6883 , C12Q2600/156
摘要： The present invention relates to a system for diagnosing Avellino corneal dystrophy, and more particularly, to a system for diagnosing Avellino corneal dystrophy which determines normality or Avellino corneal dystrophy using a first inputted PCR-amplified value to a second PCR-amplified value ratio. The system for diagnosing Avellino corneal dystrophy according to the present invention enables more simple and accurate diagnosis regardless of the skill of a doctor. Particularly, the entire process of the system of the present invention is systemized to improve the accuracy of the diagnosis and enable the easy management of multiple patients to be tested.
摘要翻译：本发明涉及一种用于诊断阿维拉氏角膜营养不良的系统，更具体地，涉及一种用于诊断使用第一个输入的PCR扩增值至第二PCR扩增值比率的正常性或阿维拉氏角膜营养不良的Avellino角膜营养不良的系统。根据本发明的用于诊断Avellino角膜营养不良的系统使得能够更简单和准确地诊断，而不管医生的技能。特别地，本发明的系统的整个过程被系统化以提高诊断的准确性，并且能够容易地管理要测试的多个患者。

2. 发明专利

JP2014113152A Multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing corneal dystrophy, and method for producing same 有权
标题翻译：多点金属沉积核酸芯片，用于诊断角膜晶状体的纳米结构阵列及其生产方法
公开(公告)号：JP2014113152A
公开(公告)日：2014-06-26
申请号：JP2014000571
申请日：2014-01-06
申请人： Korea Advanced Inst Of Science & Technology , コリアアドバンスドインスティチュートオブサイエンスアンドテクノロジィ , Avellino Co Ltd , アベリノカンパニーリミテッドAvellino Co., Ltd
发明人： LEE SANG YUP , YOO SO YOUNG , KIM DO KYUN , PARK TAE JUNG , YUN JUNG KUK , JIN YI
IPC分类号： C12N15/09 , B82Y5/00 , B82Y15/00 , B82Y40/00 , C12M1/00 , C12M1/34 , C12Q1/68
CPC分类号： C12Q1/6837 , B01J2219/00509 , B01J2219/00608 , B01J2219/00612 , B01J2219/00614 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722 , B82Y30/00 , C12Q1/6883 , C12Q2600/158
摘要： PROBLEM TO BE SOLVED: To provide a multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing corneal dystrophy, and to provide a method for diagnosing the corneal dystrophy.SOLUTION: The present invention relates to: a multi-spot metal-deposited nucleic acid chip with nanostructure arrays which uses the optical characteristics of localized surface plasmon resonance (LSPR); a method for producing the chip; and a multi-spot metal-deposited nucleic acid chip with the nanostructure arrays for diagnosing the corneal dystrophy for diagnosing BIGH3 gene mutations, which can diagnose various types of corneal dystrophies. The metal-deposited nucleic acid chip with the nanostructure arrays, and an analysis device including a light source, a detector, a spectrophotometer and a computer are combined to be used as a label-free optical biosensor based on the optical characteristics of LSPR; and a method for diagnosing the corneal dystrophy is provided by using the multi-spot metal-deposited nucleic acid chip with the nanostructure arrays for diagnosing the corneal dystrophy for diagnosing BIGH3 gene mutations.
摘要翻译：要解决的问题：提供具有用于诊断角膜营养不良的纳米结构阵列的多点金属沉积核酸芯片，并提供用于诊断角膜营养不良症的方法。解决方案：本发明涉及：多点金属 - 具有纳米结构阵列的沉积核酸芯片，其使用局部表面等离子体共振（LSPR）的光学特性; 芯片的制造方法; 和具有纳米结构阵列的多点金属沉积核酸芯片，用于诊断角膜营养不良以诊断BIGH3基因突变，其可以诊断各种类型的角膜营养不良。具有纳米结构阵列的金属沉积核酸芯片和包括光源，检测器，分光光度计和计算机的分析装置被组合以用作基于LSPR的光学特性的无标签光学生物传感器; 通过使用具有用于诊断角膜营养不良的纳米结构阵列的多点金属沉积核酸芯片来诊断角膜营养不良，诊断角膜营养不良的方法用于诊断BIGH3基因突变。

3. 发明申请

WO2012044121A2 SYSTEM FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY 审中-公开
标题翻译：系统诊断AVELLINO角膜营养不良
公开(公告)号：WO2012044121A2
公开(公告)日：2012-04-05
申请号：PCT/KR2011007272
申请日：2011-09-30
申请人： AVELLINO CO LTD , LEE GENE , YUN JUNG KUK
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： A61B3/18
CPC分类号： C12Q1/686 , C12Q1/6883 , C12Q2600/156
摘要： The present invention relates to a system for diagnosing Avellino corneal dystrophy, and more particularly, to a system for diagnosing Avellino corneal dystrophy which determines normality or Avellino corneal dystrophy using a first inputted PCR-amplified value to a second PCR-amplified value ratio. The system for diagnosing Avellino corneal dystrophy according to the present invention enables more simple and accurate diagnosis regardless of the skill of a doctor. Particularly, the entire process of the system of the present invention is systemized to improve the accuracy of the diagnosis and enable the easy management of multiple patients to be tested.
摘要翻译：本发明涉及一种系统，用于诊断阿韦利诺角膜营养不良，并且更具体地，涉及一种系统，用于诊断阿韦利诺角膜营养不良使用第一输入的PCR扩增值到第二PCR扩增的值比其确定正常或阿韦利诺角膜营养不良。无论医生的技术如何，根据本发明的用于诊断阿韦利诺角膜营养不良的系统都能够实现更简单和准确的诊断。特别是，本发明的系统的整个过程被系统化以提高诊断的准确性，并使得能够容易地管理多个患者进行测试。

4. 发明申请

WO2011021846A2 MULTI-SPOT METAL-DEPOSITED NUCLEIC ACID CHIP WITH NANOSTRUCTURE ARRAYS FOR DIAGNOSING CORNEAL DYSTROPHY, AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：纳米结构阵列用于诊断角膜营养不良的多点金属沉积的核酸芯片及其制备方法
公开(公告)号：WO2011021846A2
公开(公告)日：2011-02-24
申请号：PCT/KR2010005452
申请日：2010-08-18
申请人： KOREA ADVANCED INST SCI & TECH , AVELLINO CO LTD , LEE SANG YUP , YOO SO YOUNG , KIM DO KYUN , PARK TAE JUNG , YUN JUNG KUK , LEE GENE
发明人： LEE SANG YUP , YOO SO YOUNG , KIM DO KYUN , PARK TAE JUNG , YUN JUNG KUK , LEE GENE
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , B01J2219/00509 , B01J2219/00608 , B01J2219/00612 , B01J2219/00614 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722 , B82Y30/00 , C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing corneal dystrophy, and more particularly, to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays which uses the optical characteristics of localized surface plasmon resonance (LSPR), to a method for producing the chip, and to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing BIGH3 gene mutations and various types of corneal dystrophies. According to the present invention, the metal-deposited nucleic acid chip with nanostructure arrays, and an analysis device including a light source, a detector, a spectrophotometer and a computer are combined to be used as a label-free biosensor based on the optical characteristics of LSPR. The multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing BIGH3 gene mutations and corneal dystrophy according to the present invention diagnoses various types of corneal dystrophies, which are hereditary eye diseases, at the same time.
摘要翻译：具有纳米结构阵列的多点金属沉积核酸芯片技术领域本发明涉及用于诊断角膜营养不良的具有纳米结构阵列的多点金属沉积核酸芯片，并且更具体地涉及具有纳米结构阵列的多点金属沉积核酸芯片，其使用局部表面等离子体共振（LSPR），用于生产芯片的方法，以及具有纳米结构阵列的多点金属沉积核酸芯片，用于诊断BIGH3基因突变和各种类型的角膜营养不良。根据本发明，将具有纳米结构阵列的金属沉积核酸芯片和包括光源，检测器，分光光度计和计算机的分析装置组合以用作基于光学特性的无标记生物传感器的LSPR。根据本发明的用于诊断BIGH3基因突变和角膜营养不良的具有纳米结构阵列的多点金属沉积核酸芯片同时诊断作为遗传性眼病的各种类型的角膜营养不良。

5. 发明授权

KR101125212B1 System for diagnosis of avellino corneal dystrophy 有权
标题翻译： AVELLINO CORNEAL DYSTROPHY诊断系统
公开(公告)号：KR101125212B1
公开(公告)日：2012-03-21
申请号：KR20100096103
申请日：2010-10-01
申请人： AVELLINO CO LTD
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： A61B3/18
CPC分类号： C12Q1/686 , C12Q1/6883 , C12Q2600/156
摘要： PURPOSE: A system for diagnosis of an avellino corneal dystrophy is provided to easily manage a subject by using the ratio of a first PCR amplification value and a second PCR amplification value and determining an avellino cornea dystrophy. CONSTITUTION: A client group receives avellino cornea dystrophy discernment result data. An input unit adds a probe and receives a second PCR amplification value. An analysis unit is determined as a homozygote. An output unit outputs the discernment result data.
摘要翻译：目的：提供一种用于诊断阿维拉角膜营养不良的系统，以便通过使用第一PCR扩增值和第二PCR扩增值的比率并确定甲状腺角膜营养不良来容易地管理受试者。规定：客户群体收到avellino角膜营养不良辨别结果数据。输入单元添加探针并接收第二PCR扩增值。分析单位确定为纯合子。输出单元输出识别结果数据。

6. 发明专利

JP2013502215A Multi-spot metal deposition type nanostructure array corneal dystrophy diagnostic nucleic acid chip and this production method 有权
公开(公告)号：JP2013502215A
公开(公告)日：2013-01-24
申请号：JP2012525483
申请日：2010-08-18
申请人：コリアアドバンスドインスティチュートオブサイエンスアンドテクノロジィ , アベリノカンパニーリミテッドAvellino Co., Ltd
发明人：サンヨプイ , ソヨンユ , ドギュンキム , テジョンパク , ジョングクユン , ジンイ
IPC分类号： C12M1/00 , B82Y5/00 , B82Y40/00 , C12N15/09 , C12Q1/68 , G01N33/53 , G01N33/543 , G01N33/553 , G01N37/00
CPC分类号： C12Q1/6837 , B01J2219/00509 , B01J2219/00608 , B01J2219/00612 , B01J2219/00614 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722 , B82Y30/00 , C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to a multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing corneal dystrophy, and more particularly to a multi-spot metal-capped nanostructure array nucleic acid chip capable of employing LSPR (localized surface plasmon resonance) optical properties, a preparation method thereof, and a multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing BIGH3 gene mutations, which can diagnose various corneal dystrophies. According to the invention, the metal-capped nanostructure array nucleic acid chip can be combined with analysis devices, including a light source, a detector, a spectrophotometer and a computer, to provide an LSPR optical property-based optical biosensor, and the use of the multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing BIGH3 gene mutations allows the simultaneous diagnosis of various corneal dystrophies that are genetic ocular diseases.

7. 发明专利

BRPI0924016A2 par de primer para diagnóstico de distrofia corneana de avellino 未知
公开(公告)号：BRPI0924016A2
公开(公告)日：2016-10-11
申请号：BRPI0924016
申请日：2009-12-01
申请人： AVELLINO CO LTD
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： C12N15/11 , C12Q1/68

8. 发明专利

ZA201107967B PRIMERS FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY 未知
公开(公告)号：ZA201107967B
公开(公告)日：2013-08-28
申请号：ZA201107967
申请日：2011-10-14
申请人： AVELLINO CO LTD ET ALL
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： C12Q20060101 , C12N20060101
摘要： The present invention relates to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, and more particularly to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, which can accurately diagnose the presence or absence of a mutation in exon 4 of BIGH3 gene, which is responsible for Avellino corneal dystrophy. The use of the primer pair and probe according to the invention can diagnose Avellino corneal dystrophy in a more rapid and accurate manner than a conventional method that uses a DNA chip or PCR.

9. 发明专利

CA2759222A1 PRIMER FOR DIAGNOSING AVELLINO CORNEAL SYSTROPHY 未知
公开(公告)号：CA2759222A1
公开(公告)日：2010-10-21
申请号：CA2759222
申请日：2009-12-01
申请人： AVELLINO CO LTD
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： C12N15/11 , C12Q1/68
摘要： The present invention relates to a pair of real-time PCR primers and to a probe for detecting Avellino corneal dystrophy. More particularly, the present invention relates to a pair of real-time PCR primers and to a probe for detecting Avellino corneal dystrophy, which can accurately detect the presence or absence of a mutation in exon 4 of the BIGH3 gene which causes Avellino corneal dystrophy. By using the pair of primers and the probe of the present invention, Avellino corneal dystrophy can be more quickly and accurately detected as compared to conventional methods for detecting Avellino corneal dystrophy using a DNA chip or PCR.

10. 发明专利

SG175732A1 PRIMER FOR DETECTING AVELLINO CORNEAL DYSTROPHY 未知
公开(公告)号：SG175732A1
公开(公告)日：2011-12-29
申请号：SG2011075728
申请日：2009-12-01
申请人： AVELLINO CO LTD
发明人： LEE GENE , YUN JUNG KUK
摘要： The present invention relates to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, and more particularly to a real-time PCR primer pair and probe5 for diagnosing Avellino corneal dystrophy, which can accurately diagnose the presence or absence of a mutation in exon 4 of BIGH3 gene, which is responsible for Avellino corneal dystrophy. The use of the primer pair and probe according to the invention can diagnose Avellino corneal10 dystrophy in a more rapid and accurate manner than a conventional method that uses a DNA chip or PCR.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式