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81. 发明授权

US06355688B1 Remedy for autoimmune diseases 失效
标题翻译：补救自身免疫性疾病
公开(公告)号：US06355688B1
公开(公告)日：2002-03-12
申请号：US09516435
申请日：2000-03-01
申请人： Junpei Itoh , Osamu Miyazaki , Hisao Ekimoto , Michinori Koyama , Tetsushi Saino , Lauri Kangas , Anni Warri , Christer Granberg
发明人： Junpei Itoh , Osamu Miyazaki , Hisao Ekimoto , Michinori Koyama , Tetsushi Saino , Lauri Kangas , Anni Warri , Christer Granberg
IPC分类号： A61K31135
CPC分类号： A61K31/138 , A61K31/00 , A61K31/135 , A61K31/56 , A61K31/57 , A61K2300/00
摘要： Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
摘要翻译：公开了使用非甾体抗雌激素化合物如托瑞米芬柠檬酸盐作为治疗自身免疫疾病的活性成分。

82. 发明授权

US6061422A X-ray ct apparatus and an image reconstructing method for obtaining a normal reconstructed image by adding weights to a plurality of partial reconstructed images 失效
标题翻译： X射线CT装置和用于通过向多个部分重建图像添加权重来获得正常重建图像的图像重建方法
公开(公告)号：US6061422A
公开(公告)日：2000-05-09
申请号：US69773
申请日：1998-04-30
申请人： Osamu Miyazaki , Tetsuo Nakazawa
发明人： Osamu Miyazaki , Tetsuo Nakazawa
IPC分类号： G06T11/00 , A61B6/03
CPC分类号： G06T11/006 , Y10S378/901
摘要： An image reconstructing method in relation to an X-ray CT apparatus for shifting, sequentially by a predetermined angle, a reconstructed image for a projection angle in a predetermined range so as to obtain a continuous reconstructed image, in which one normal reconstructed image is obtained as follows: First, 180.degree. amount of parallel beam projection data, which is obtained by converting fan beam measurement data into parallel beam data, is divided at a predetermined angle so as to obtain each partial reconstructed image for each partial segment. Then, weight-imposing is performed on the plurality of partial reconstructed images obtained, and the weight-imposed images are superposed, thus obtaining the one sheet of normal reconstructed image. At that time, concerning partial reconstructed images the view angles of which are in an opposing relationship to each other, a weighted average thereof is determined.
摘要翻译：一种与X射线CT装置相关的图像重建方法，用于以预定角度依次移动用于预定范围内的投影角度的重建图像，以获得连续重建图像，其中获得一个正常重建图像如下：首先，将扇形光束测量数据转换成平行光束数据而获得的180度平行光束投影数据以预定角度分割，以获得每个部分片段的每个部分重建图像。然后，对所获得的多个部分重建图像进行加权，并且将加权图像叠加，从而获得一张正常重建图像。此时，关于其视角彼此具有相反关系的部分重构图像，确定其加权平均值。

83. 发明授权

US5886049A Remedy for autoimmune diseases 失效
公开(公告)号：US5886049A
公开(公告)日：1999-03-23
申请号：US844846
申请日：1997-04-22
申请人： Junpei Itoh , Osamu Miyazaki , Hisao Ekimoto , Michinori Koyama , Tetsushi Saino , Lauri Kangas , Anni Warri , Christer Granberg
发明人： Junpei Itoh , Osamu Miyazaki , Hisao Ekimoto , Michinori Koyama , Tetsushi Saino , Lauri Kangas , Anni Warri , Christer Granberg
IPC分类号： A61K31/135 , A61K31/138 , A61K31/56
CPC分类号： A61K31/138 , A61K31/135 , A61K31/56
摘要： Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.

84. 发明授权

US5514850A Defect compensation method for smoothing a surface of a transparent plate with an ArF excimer laser beam 失效
标题翻译：用ArF准分子激光束平滑透明板表面的缺陷补偿方法
公开(公告)号：US5514850A
公开(公告)日：1996-05-07
申请号：US64275
申请日：1993-05-19
申请人： Osamu Miyazaki , Kazuya Yoshimura , Syunji Nakai
发明人： Osamu Miyazaki , Kazuya Yoshimura , Syunji Nakai
IPC分类号： B23K26/06 , B23K26/40 , B29C35/08 , B29C59/16 , C03B29/00 , B23K26/00
CPC分类号： C03B29/00 , B23K26/066 , B23K26/402 , B29C59/16 , B23K2203/42 , B29C2035/0838 , B29K2995/0026 , Y02P40/57
摘要： A defect compensation method for smoothing a surface of a transparent plate by radiating an ArF excimer laser beam to a defect at the surface. The ArF excimer laser beam is radiated by use of a mask having an opening which is shaped in accordance with the shape of the defect, through a lens, or while the size of the beam at the defect is changed to a plurality of values. As the mask, an iris mask having an opening which is larger than the defect is usable. The size of the beam is changed by exchanging, a plurality of masks each having an opening of a different size from one another, or by use of a mask having a plurality of openings of different sizes. Alternatively, the ArF excimer laser beam is radiated so as to have an energy which is high at a center and low at a periphery of the defect. Or, the ArF excimer laser beam has a smaller size than the size of the defect, and the transparent plate having the defect is moved so as to allow different portions of the defect to be irradiated sequentially by the ArF excimer laser beam and simultaneously the number of shots of the ArF excimer laser beam is changed.
摘要翻译：一种用于通过将ArF准分子激光束照射到表面的缺陷来使透明板的表面平滑的缺陷补偿方法。通过使用具有根据缺陷的形状成形的开口的掩模，通过透镜，或者在缺陷处的光束的尺寸变为多个值的同时辐射ArF准分子激光束。作为掩模，可以使用具有大于缺陷的开口的虹膜掩模。通过交换具有彼此不同大小的开口的多个掩模，或者通过使用具有多个不同尺寸的开口的掩模来改变光束的尺寸。或者，ArF准分子激光束被辐射，以具有在缺陷的中心处为高的能量，在缺陷的周围为低的能量。或者，ArF准分子激光束的尺寸比缺陷的尺寸小，并且具有缺陷的透明板被移动，以使缺陷的不同部分被ArF准分子激光束依次照射，同时数量 ArF准分子激光束的射击发生变化。

85. 发明授权

US5454019A Computed tomography system 失效
标题翻译：计算机断层扫描系统
公开(公告)号：US5454019A
公开(公告)日：1995-09-26
申请号：US851930
申请日：1992-03-16
申请人： Shinichi Migita , Osamu Miyazaki , Testuo Nakazawa
发明人： Shinichi Migita , Osamu Miyazaki , Testuo Nakazawa
IPC分类号： A61B6/03 , G01N23/04 , G06T11/00 , G01N23/083
CPC分类号： A61B6/032 , G01N23/046 , G06T11/005 , G01N2223/419 , G01N2223/612 , Y10S378/901
摘要： A computed tomography system includes an image reconstruction data generator for generating image reconstruction data for a desired slice plane of an object in accordance with measuring projection data, the image reconstruction data being obtained from measuring projection data obtained at each of a plurality of rotation positions of a radiation source, and an image reconstructor for obtaining tomographic image data of the object for the desired slice plane in accordance with the image reconstruction data. The image reconstruction data generator has the capability of grouping the measuring projection data into a plurality of groups respectively corresponding to a plurality of desired slice planes of the object, the desired slice planes being spaced apart from each other by a distance corresponding to one rotation position of the radiation source, with each of the groups corresponding to a continuous rotation range of 360.degree. of the radiation source, and successively using the measuring projection data of each group for the image reconstruction data.
摘要翻译：计算机断层摄影系统包括图像重建数据发生器，用于根据测量投影数据产生对象的期望切片平面的图像重建数据，所述图像重建数据是从测量在多个旋转位置辐射源，以及图像重建器，用于根据图像重建数据获得用于期望切片平面的物体的断层图像数据。图像重建数据生成器具有将测量投影数据分组成分别对应于对象的多个期望切片平面的多个组的能力，期望的切片平面彼此间隔一个相当于一个旋转位置的距离的辐射源，其中每个组对应于辐射源的360°的连续旋转范围，并且连续地使用每组的测量投影数据作为图像重建数据。

86. 发明授权

US4888658A Magnetic head for magnetic recording and reproducing unit 失效
标题翻译：用于磁记录和再现单元的磁头
公开(公告)号：US4888658A
公开(公告)日：1989-12-19
申请号：US175605
申请日：1988-04-01
申请人： Mitsuaki Ono , Masataka Ueda , Osamu Miyazaki
发明人： Mitsuaki Ono , Masataka Ueda , Osamu Miyazaki
IPC分类号： G11B5/187
CPC分类号： G11B5/1871 , Y10T29/49043 , Y10T29/49052 , Y10T29/49057 , Y10T29/49067
摘要： In a magnetic head comprising a head gap and a magnetic core composed of both a high permeability ferrite and a magnetic alloy, said magnetic alloy being disposed in the vicinity of said head gap,the improvement comprising a corrugation provided at a junction portion between said ferrite and said magnetic alloy, a height of said corrugation being not less than a value of the longest wavelength of luminance signals and color signals recorded on a magnetic recording medium, a distance defined between adjacent two crests or bottoms of said corrugation being smaller than a width of a head track.

87. 发明授权

US4789929A CT system for spirally scanning subject on a movable bed synchronized to X-ray tube revolution 失效
标题翻译： CT系统用于与X射线管革命同步的可移动床上的螺旋扫描对象
公开(公告)号：US4789929A
公开(公告)日：1988-12-06
申请号：US49802
申请日：1987-05-14
申请人： Hiroshi Nishimura , Osamu Miyazaki
发明人： Hiroshi Nishimura , Osamu Miyazaki
IPC分类号： A61B6/03 , G06T11/00 , G01N23/04
CPC分类号： A61B6/032 , A61B6/027 , G06T11/006 , G06T2211/421
摘要： A computerized tomography system which includes an X-ray generator for producing X-rays, an X-ray detector array for detecting the X-rays transmitted through a subject, and a subject bed. The X-ray tube and the X-ray detectors are opposed to each other, and the X-ray beams are irradiated upon the subject in a sectorial manner at a large number of angles to scan the subject while the X-ray tube and the X-ray detectors are being revolved around the subject, the X-ray tube and X-ray detectors remaining opposed to each other the during revolution. The system includes a system for rapidly and continuously revolving a frame bearing the X-ray tube, a system for moving the subject bed perpendicularly to a plane of revolution of the X-ray tube and for moving the subject bed synchronously with the revolution of the X-ray tube, a system for scanning the subject along with the movement of the subject bed in a spiral with respect to a coordinate system positioned about an imaginary axis passing through the subject, and a system for obtaining a reconstructed tomogram of an arbitrary cross-section within a range from a position corresponding to a beginning of the spiral scanning to a position corresponding to an end of the spiral scanning. A method of operating the computerized tomography system is also provided.
摘要翻译：一种计算机断层摄影系统，其包括用于产生X射线的X射线发生器，用于检测通过被摄体透射的X射线的X射线检测器阵列和被摄体床。 X射线管和X射线检测器彼此相对，并且X射线束以大量的角度以扇形方式照射在被检体上，以在X射线管和 X射线探测器围绕被摄体旋转，X射线管和X射线探测器在旋转期间彼此相对。该系统包括用于快速且连续地旋转承载X射线管的框架的系统，用于使被摄体床垂直于X射线管的旋转平面移动的系统，并且用于与主体床同步旋转的系统 X射线管，用于扫描受试者的系统以及主体床相对于穿过受试者的假想轴定位的坐标系的螺旋运动的系统，以及用于获得任意交叉的重建断层图像的系统在从与螺旋扫描的开始相对应的位置到与螺旋扫描的结束对应的位置的范围内。还提供了一种操作计算机断层摄影系统的方法。

88. 发明授权

US4726474A Circulating-type bill depositing and disbursing machine 失效
标题翻译：循环式票据存款和发货机
公开(公告)号：US4726474A
公开(公告)日：1988-02-23
申请号：US729111
申请日：1985-04-30
申请人： Junichi Arikawa , Hiroshi Chiba , Osamu Miyazaki , Masatoshi Osanai
发明人： Junichi Arikawa , Hiroshi Chiba , Osamu Miyazaki , Masatoshi Osanai
IPC分类号： G07D11/00 , B07C5/36
CPC分类号： G07D11/0081
摘要： The circulating-type bill depositing and disbursing machine includes a receiving and dispensing box. The receiving and dispensing box is adapted to be removably loaded into the machine. The box receives undamaged bills in the front portion thereof to allow the undamaged bills to be dispensed therefrom and also receives damaged bills in the rear portion thereof.
摘要翻译：循环型票据收存机包括收发箱。接收和分配盒适于可拆卸地装载到机器中。盒子的前部接收未损坏的纸币，以使未损坏的纸币从其中分出，并在其后部接收损坏的纸币。

89. 发明授权

US09341633B2 Method for pre-treating sample containing glycated hemoglobin 有权
标题翻译：预处理含有糖化血红蛋白的样品的方法
公开(公告)号：US09341633B2
公开(公告)日：2016-05-17
申请号：US13139239
申请日：2009-12-10
申请人： Osamu Miyazaki , Syunsuke Kurashita , Kohei Takubo
发明人： Osamu Miyazaki , Syunsuke Kurashita , Kohei Takubo
IPC分类号： G01N33/72
CPC分类号： G01N33/723 , G01N2400/02 , G01N2440/38
摘要： There are provided a pre-treatment technique for a glycated hemoglobin-containing sample, which is a simple and convenient treatment, is free from problems in storage stability and environmental aspects, and is capable of exposing an epitope sufficiently in a short time; and an method for an immunological assay of glycated hemoglobin using this technique.A method for pre-treating a glycated hemoglobin-containing sample for an immunological assay of glycated hemoglobin, the method includes treating a glycated hemoglobin-containing sample with a pre-treatment solution containing (A) guanidine or a salt thereof and (B) a nonionic surfactant and/or a nitrite.
摘要翻译：提供了含有糖化血红蛋白的样品的预处理技术，其是简单且方便的处理，在储存稳定性和环境方面没有问题，并且能够在短时间内充分暴露表位; 以及使用该技术的糖化血红蛋白的免疫测定方法。一种用于对糖化血红蛋白的免疫学测定进行预处理的糖化血红蛋白样品的方法，所述方法包括用含有（A）胍或其盐的预处理溶液处理含糖血红蛋白的样品，和（B）非离子表面活性剂和/或亚硝酸盐。

90. 发明授权

US09169320B2 Antibody to N-terminal region of hemoglobin β-chain 有权
标题翻译：血红蛋白N末端区域的抗体和链
公开(公告)号：US09169320B2
公开(公告)日：2015-10-27
申请号：US13139201
申请日：2009-12-10
申请人： Osamu Miyazaki , Kohei Takubo , Syunsuke Kurashita
发明人： Osamu Miyazaki , Kohei Takubo , Syunsuke Kurashita
IPC分类号： C07K16/18 , C12N5/20 , G01N33/531 , G01N33/72 , C12N5/16 , C07K14/805
CPC分类号： C07K16/18 , C07K14/805 , C07K2317/14 , C07K2317/33 , C07K2317/34 , C12N5/163 , G01N33/531 , G01N33/721 , G01N33/723
摘要： Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified.
摘要翻译：提供了能够测量与IFCC参考方法相当的HbA1c含量的通用技术。与N末端缬氨酸未被修饰但不与肽或蛋白质反应的N末端与具有VHLTPE（SEQ ID NO：1）氨基酸序列的氨基酸序列的肽或蛋白质反应的抗体其中相关多肽或蛋白质的N-末端缬氨酸被修饰。

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