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81. 发明授权

US06178130B1 Apparatus and method for refreshing subsets of memory devices in a memory system 有权
标题翻译：用于刷新存储器系统中存储器件子集的装置和方法
公开(公告)号：US06178130B1
公开(公告)日：2001-01-23
申请号：US09169590
申请日：1998-10-09
申请人： Ely K. Tsern , Richard M. Barth , Paul G. Davis , Craig E. Hampel , Thomas J. Holman , Andrew V. Anderson
发明人： Ely K. Tsern , Richard M. Barth , Paul G. Davis , Craig E. Hampel , Thomas J. Holman , Andrew V. Anderson
IPC分类号： G11C700
CPC分类号： G11C11/406
摘要： A memory system includes a set of memory devices. An interconnect structure links the set of memory devices to one another. A memory controller is connected to the interconnect structure. The memory controller is configured to apply a control signal to the interconnect structure such that a specified subset of the set of memory devices performs a refresh operation.
摘要翻译：存储器系统包括一组存储器件。互连结构将存储器件集合彼此连接。存储器控制器连接到互连结构。存储器控制器被配置为将控制信号施加到互连结构，使得该组存储器件的指定子集执行刷新操作。

82. 发明授权

US6075730A High performance cost optimized memory with delayed memory writes 有权
标题翻译：高性能的成本优化了内存延迟记忆
公开(公告)号：US6075730A
公开(公告)日：2000-06-13
申请号：US169729
申请日：1998-10-09
申请人： Richard M. Barth , Frederick A. Ware , Donald C. Stark , Craig E. Hampel , Paul G. Davis , Abhijit M. Abhyankar , James A. Gasbarro , David Nguyen , Thomas J. Holman , Andrew V. Anderson , Peter D. MacWilliams
发明人： Richard M. Barth , Frederick A. Ware , Donald C. Stark , Craig E. Hampel , Paul G. Davis , Abhijit M. Abhyankar , James A. Gasbarro , David Nguyen , Thomas J. Holman , Andrew V. Anderson , Peter D. MacWilliams
IPC分类号： G11C7/10 , G11C7/22 , G11C7/00
CPC分类号： G11C7/22 , G11C7/1072 , G11C2207/229
摘要： A memory device includes an interconnect with control pins and bidirectional data pins. A memory core stores data. A memory interface circuit is connected to the interconnect and the memory core. The memory interface circuit includes a delay circuit to establish a write delay during a memory core write transaction such that the memory core write transaction has a processing time that is substantially equivalent to a memory core read transaction. The delay circuit delays the memory core write transaction for a time corresponding to the time required for signals to travel on the interconnect.
摘要翻译：存储器件包括具有控制引脚和双向数据引脚的互连。内存核心存储数据。存储器接口电路连接到互连和存储器核。存储器接口电路包括延迟电路，以在存储器核心写入事务期间建立写入延迟，使得存储器核心写入事务具有基本上等同于存储器核心读取事务的处理时间。延迟电路将存储器核心写入事务延迟一段时间，该时间对应于信号在互连上行进所需的时间。

83. 发明授权

US6005776A Vertical connector based packaging solution for integrated circuits 失效
标题翻译：用于集成电路的垂直连接器封装解决方案
公开(公告)号：US6005776A
公开(公告)日：1999-12-21
申请号：US2775
申请日：1998-01-05
申请人： Thomas J. Holman , Michael W. Leddige
发明人： Thomas J. Holman , Michael W. Leddige
IPC分类号： H01L25/065 , H05K1/18 , H05K3/34 , H05K7/02 , H05K1/16 , H01L23/12 , H01L23/488
CPC分类号： H05K7/023 , H01L25/0657 , H05K1/181 , H01L2225/0651 , H01L2225/06551 , H01L2225/06572 , H01L2924/0002 , H01L2924/3011 , H05K2201/10159 , H05K2201/10454 , H05K2201/10681 , H05K2201/10689 , H05K3/3436 , Y02P70/611
摘要： An assembly featuring a substrate and a plurality of components. The plurality of components are packaged to be connected in a vertical orientation to the substrate. These components include (i) a vertical chip-scale package (CSP), (ii) an integrated circuit die and (iii) an interconnect. Including a plurality of connection leads, the vertical CSP contains the die which is generally situated along a vertical plane. The interconnect, capable of transferring information between the plurality of connection leads and the integrated circuit die, includes a first segment generally perpendicular to the vertical plane and connected to at least one connection lead. The interconnect further includes a second segment generally in parallel to the vertical plane and connected to the integrated circuit die.
摘要翻译：一种具有基板和多个部件的组件。多个部件被封装成垂直定向地连接到基板。这些组件包括（i）垂直芯片级封装（CSP），（ii）集成电路管芯和（iii）互连。包括多个连接引线，垂直CSP包含通常沿垂直平面定位的管芯。能够在多个连接引线和集成电路管芯之间传送信息的互连件包括大致垂直于垂直平面并连接到至少一个连接引线的第一段。互连还包括大致平行于垂直平面并连接到集成电路管芯的第二段。

84. 发明授权

US5856987A Encoder and decoder for an SEC-DED-S4ED rotational code 失效
标题翻译：用于SEC-DED-S4ED旋转码的编码器和解码器
公开(公告)号：US5856987A
公开(公告)日：1999-01-05
申请号：US801617
申请日：1997-02-18
申请人： Thomas J. Holman
发明人： Thomas J. Holman
IPC分类号： H03M7/36 , H03M13/15 , H03M13/00
CPC分类号： H03M13/151
摘要： A computer system employs a SEC-DED-S4ED rotational error control code (ECC) wherein all columns of H matrix are linearly independent and have an odd weight, and are arranged to allow detection of 4-bit byte errors. The ECC includes check bits arranged in a specific manner in designated columns of the matrix to permit detection and correction of single bit errors, as well as detection of double, triple and quadruple bit errors. The computer system employing the ECC also includes a data path having a variety of implementations; e.g., a single 72-bit path, two 36-bit paths, or a single 36-bit path.
摘要翻译：计算机系统采用SEC-DED-S4ED旋转误差控制码（ECC），其中H矩阵的所有列都是线性独立的并且具有奇数权重，并且被布置为允许检测4位字节错误。 ECC包括以特定方式布置在矩阵的指定列中的校验位，以允许检测和校正单个位错误，以及检测双重，三重和四重位错误。采用ECC的计算机系统还包括具有各种实现的数据路径; 例如单个72位路径，两个36位路径或单个36位路径。

85. 发明授权

US08690824B2 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US08690824B2
公开(公告)日：2014-04-08
申请号：US13441664
申请日：2012-04-06
申请人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

86. 发明授权

US08538515B2 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 有权
标题翻译：用于与电力源一起递送治疗剂的内部医疗装置
公开(公告)号：US08538515B2
公开(公告)日：2013-09-17
申请号：US12939363
申请日：2010-11-04
申请人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
发明人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
IPC分类号： A61N1/30
CPC分类号： A61N1/325 , A61N1/05 , A61N1/306 , A61N1/327
摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.
摘要翻译：本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。此外，治疗剂源适于将治疗剂引入电场。另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。

87. 发明授权

US08404165B2 Catheter distal tip design and method of making 有权
标题翻译：导管远端尖端设计及制作方法
公开(公告)号：US08404165B2
公开(公告)日：2013-03-26
申请号：US11262690
申请日：2005-10-31
申请人： Jan Weber , Thomas J. Holman
发明人： Jan Weber , Thomas J. Holman
IPC分类号： B29C37/02
CPC分类号： A61M25/0068 , A61M25/001 , A61M25/008 , A61M2025/0081 , A61M2025/1093 , B23K2103/42 , B23K2103/50
摘要： A catheter comprises a catheter shaft having a distal tip, the distal tip having an inner surface and an outer surface, the inner surface having a rounded profile. The catheter may be made by rounding the inner surface of the distal tip.
摘要翻译：导管包括具有远侧末端的导管轴，所述远侧末端具有内表面和外表面，所述内表面具有圆形轮廓。导管可以通过使远侧末端的内表面四舍五入而制成。

88. 发明授权

US08303537B2 Balloon catheter tip design 有权
标题翻译：气球导管尖端设计
公开(公告)号：US08303537B2
公开(公告)日：2012-11-06
申请号：US12537324
申请日：2009-08-07
申请人： Thomas J. Holman , Daniel Keith Tomaschko , Leo M. Klisch , Richard Olson , Joseph M. Lyver , Richard Dunn , Nie Tang , Lixiao Wang , David Griswold
发明人： Thomas J. Holman , Daniel Keith Tomaschko , Leo M. Klisch , Richard Olson , Joseph M. Lyver , Richard Dunn , Nie Tang , Lixiao Wang , David Griswold
IPC分类号： A61M29/00
CPC分类号： A61M25/1034 , A61M25/0069 , A61M25/104 , A61M2025/1093
摘要： The present invention is directed to distal tip designs for catheter, wherein distal tip material is positioned about an inner shaft. The distal tip material may also be used as a tie layer for thermally bonding two incompatible materials together, such as a waist portion of a balloon to the inner shaft.
摘要翻译：本发明涉及用于导管的远侧末端设计，其中远侧末端材料围绕内部轴定位。远侧末端材料也可以用作将两个不相容材料（例如球囊的腰部部分）一起热粘合到内轴的连接层。

89. 发明授权

US08153181B2 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US08153181B2
公开(公告)日：2012-04-10
申请号：US11599052
申请日：2006-11-14
申请人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
IPC分类号： B05D3/14 , A61M31/00
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

90. 发明申请

US20120046608A1 Medical Devices 有权
标题翻译：医疗设备
公开(公告)号：US20120046608A1
公开(公告)日：2012-02-23
申请号：US13285518
申请日：2011-10-31
申请人： Daniel J. Horn , John Jianhua Chen , Jan Weber , Thomas J. Holman
发明人： Daniel J. Horn , John Jianhua Chen , Jan Weber , Thomas J. Holman
IPC分类号： A61M25/10 , B05D3/00 , B05D3/10 , B05D7/00 , B05D5/00
CPC分类号： A61M25/104 , A61F2002/9583 , A61F2250/0068 , A61L29/126 , A61M2025/1086
摘要： The invention relates to medical balloons, and methods of modifying said balloons by forming a void pattern in their exterior surfaces and filling the voids with a material, such as a fiber or a nanomaterial (e.g., nanotubes, such as carbon nanotubes) and a matrix material, e.g., a polymer.
摘要翻译：本发明涉及医用气囊，以及通过在其外表面上形成空隙图案并用诸如纤维或纳米材料（例如纳米管，例如碳纳米管）和基体材料，例如聚合物。

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