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81. 发明授权

US4296106A Istamycins and production thereof 失效
标题翻译：伊曲霉素及其生产
公开(公告)号：US4296106A
公开(公告)日：1981-10-20
申请号：US141492
申请日：1980-04-18
申请人： Hamao Umezawa , Yoshiro Okami , Shinichi Kondo
发明人： Hamao Umezawa , Yoshiro Okami , Shinichi Kondo
IPC分类号： C07H15/224 , C12P19/48 , A61K31/71 , C07H15/22
CPC分类号： C07H15/224 , C12P19/48 , C12R1/465
摘要： Four new antibiotics which are denominated istamycin A, istamycin B, istamycin A.sub.o and istamycin B.sub.o, and which are useful as antibacterial agents, are produced by fermentation of a new microorganism, Streptomyces tenjimariensis.
摘要翻译：以新霉素Streptomyces tenjimariensis的发酵产生的四种新型抗生素，其为Isim霉素A，伊曲霉素B，伊曲霉素Ao和伊曲霉素Bb，可用作抗菌剂。

82. 发明授权

US4140849A Kanamycin C derivatives 失效
标题翻译：卡那霉素C衍生物
公开(公告)号：US4140849A
公开(公告)日：1979-02-20
申请号：US834753
申请日：1977-09-19
申请人： Hamao Umezawa , Shinichi Kondo
发明人： Hamao Umezawa , Shinichi Kondo
IPC分类号： C07H15/236 , C07H15/22
CPC分类号： C07H15/234
摘要： 1-N-(L-4-amino-2-hydroxybutyryl) derivatives of kanamycin C, 3'-deoxykanamycin C and 3',4'-dideoxykanamycin C have been prepared which possess high antibacterial activity against a wide variety of drug-resistant bacteria. These new derivatives are prepared by reacting L-4-amino-2-hydroxybutyric acid or a functional equivalent thereof with the 1-amino group of kanamycin C, 3'-deoxykanamycin C or 3',4'-dideoxykanamycin C.
摘要翻译：已经制备了卡那霉素C，3'-脱氧卡那霉素C和3'，4'-二脱氧卡那霉素C的1-N-（L-4-氨基-2-羟基丁酰基）衍生物，其具有针对各种耐药性的高抗菌活性菌。这些新的衍生物通过使L-4-氨基-2-羟基丁酸或其功能等同物与卡那霉素C，3'-脱氧卡那霉素C或3'，4'-二脱氧卡那霉素C的1-氨基反应制备。

83. 发明授权

US4120955A Method for production of kanamycin C and its derivatives 失效
标题翻译：卡那霉素C及其衍生物的生产方法
公开(公告)号：US4120955A
公开(公告)日：1978-10-17
申请号：US799806
申请日：1977-05-23
申请人： Hamao Umezawa , Shinichi Kondo
发明人： Hamao Umezawa , Shinichi Kondo
IPC分类号： C07H15/234 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61P31/04 , C07H15/236 , A61K31/71 , C07H15/22
CPC分类号： C07H15/234 , Y02P20/55
摘要： Kanamycin C, 3'-deoxykanamycin C and 3'4'-dideoxykanamycin C are obtained by a new process comprising treating the primary 6'-amino group of a tetra-N-protected derivative of kanamycin B, 3'-deoxykanamycin B and 3', 4'-dideoxykanamycin B with a nitrite to convert said amino group into hydroxyl group and then removing the protective groups. 3'-Deoxykanamycin C and 3', 4'-dideoxykanamycin C are new semi-synthetic aminoglycosidic antibiotics.
摘要翻译：卡那霉素C，3'-脱氧卡那霉素C和3'4'-二脱氧卡那霉素C通过新方法获得，包括处理卡那霉素B，3'-脱氧卡那霉素B和3'-脱氧卡那霉素B的四-N-保护的衍生物的原始6'-氨基 '，4'-双脱氧卡那霉素B与亚硝酸盐反应，将所述氨基转化为羟基，然后除去保护基。 3'-脱氧卡那霉素C和3'，4'-二脱氧卡那霉素C是新的半合成氨基糖苷类抗生素。

84. 发明授权

US4008362A 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin and the production thereof 失效
标题翻译： 1-N - （（S） - {60-取代的 - {107-氨基酰基） - 纳米颗粒或 - 瑞波霉素及其制备
公开(公告)号：US4008362A
公开(公告)日：1977-02-15
申请号：US390217
申请日：1973-08-21
申请人： Eiichi Akita , Tsutomu Tsuchiya , Shinichi Kondo , Shuntaro Yasuda , Sumio Umezawa , Hamao Umezawa
发明人： Eiichi Akita , Tsutomu Tsuchiya , Shinichi Kondo , Shuntaro Yasuda , Sumio Umezawa , Hamao Umezawa
IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61K31/704 , A61P31/04 , C07H15/224 , C07H15/23 , C07H15/244
CPC分类号： C07H15/224 , C07H15/23
摘要： An 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin of the formula ##STR1## wherein R is a hydrogen atom or .beta.-D-ribofuranosyl group of the formula ##STR2## and R.sub.3 is hydroxyl, amino-NH.sub.2 or acylamino group --NHR.sub.4 in which R.sub.4 is an acyl group, and n is a whole number of 1 to 4, may be produced by subjecting the corresponding O-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin of the formula ##STR3## or its hydroxyl-masked and maino-masked form, to the action of a basic medium to produce an acyl-migration product of the formula: ##STR4## and, optionally converting the amino-masking groups into hydrogen atoms and also the hydroxyl-masking group into hydroge atom in a known manner if said amino-masking groups and said hydroxyl-masking groups are present in the acyl-migration product. The 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin produced is characterized by its useful activity inhibitory to the growth of bacteria resistant to the parent substance neamine or ribostamycin.
摘要翻译：式（1）的1-N - （（S）-α-取代的ω-氨基酰基） - 单胺或-ribostamycin，其中R为氢原子或式为“IMAGE”的β-D-呋喃核糖基，R3为是其中R 4为酰基，n为整数1至4的羟基，氨基-NH 2或酰基氨基-NHR 4，其可以通过使相应的O - （（S）-α-取代的ω- 氨基酰基） - 奈米霉素或结晶霉素或其羟基掩蔽和主掩蔽形式，与碱性介质的作用产生下式的酰基迁移产物：和/或将如果所述氨基掩蔽基团和所述羟基掩蔽基团存在于酰基迁移产物中，则以已知方式将氨基掩蔽基团转化成氢原子，并将羟基掩蔽基团转变成水解原子。产生的1-N - （（S）-α-取代的ω-氨基酰基） - 单胺或 - 生物素 - 特异霉素的特征在于其对母体neamine或核糖霉素具有抗性的细菌的生长有抑制作用。

85. 发明授权

US4008218A 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin and the production thereof 失效
标题翻译： 1-N - （（S） - {60-取代的 - {107-氨基酰基） - 纳米颗粒或 - 瑞波霉素及其制备
公开(公告)号：US4008218A
公开(公告)日：1977-02-15
申请号：US559771
申请日：1975-03-19
申请人： Eiichi Akita , Tsutomu Tsuchiya , Shinichi Kondo , Shuntaro Yasuda , Sumio Umezawa , Hamao Umezawa
发明人： Eiichi Akita , Tsutomu Tsuchiya , Shinichi Kondo , Shuntaro Yasuda , Sumio Umezawa , Hamao Umezawa
IPC分类号： C07H15/224 , C07H15/23 , C07G11/00
CPC分类号： C07H15/224 , C07H15/23
摘要： An 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin of the formula: ##STR1## wherein R is a hydrogen atom or .beta.-D-ribofuranosyl group of the formula ##STR2## and R.sub.3 is hydroxyl, amino-NH.sub.2 or acylamino group --NHR.sub.4 in which R.sub.4 is an acyl group, and n is a whole number of 1 to 4, may be produced by subjecting the corresponding O-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin of the formula ##STR3## or its hydroxyl-masked and amino-masked form, to the action of a basic medium to produce an acyl-migration product of the formula: ##STR4## and, optionally converting the amino-masking groups into hydrogen atoms and also the hydroxyl-masking group into hydrogen atom in a known manner if said amino-masking groups and said hydroxyl-masking groups are present in the acyl-migration product. The 1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin produced is characterized by its useful activity inhibitory to the growth of bacteria resistant to the parent substance neamine or ribostamycin.
摘要翻译：具有下式的1-N - （（S）-α-取代的ω-氨基酰基） - 微量胺或 - 瑞波霉素：其中R是式“IMAGE”的氢原子或β-D-呋喃核糖基， R 3是羟基，氨基-NH 2或酰基氨基-NHR 4，其中R 4是酰基，n是整数1至4，可以通过使相应的O - （（S）-α-取代的-ω- - 氨基酰基） - 或者其羟基掩蔽和氨基掩蔽形式的微生物胺或β-内啡霉素或碱性培养基，以产生下式的酰基迁移产物：如果所述氨基掩蔽基团和所述羟基掩蔽基团存在于酰基迁移产物中，则以已知的方式将氨基掩蔽基团转化成氢原子，并将羟基掩蔽基团转变为氢原子。产生的1-N - （（S）-α-取代的ω-氨基酰基） - 单胺或 - 生物霉素的特征在于其对母体neamine或核糖霉素具有抗性的细菌的生长有抑制作用。

86. 发明授权

US3959257A Production of coformycin and intermediates therefor 失效
标题翻译：共生霉素及其中间体
公开(公告)号：US3959257A
公开(公告)日：1976-05-25
申请号：US518030
申请日：1974-10-24
申请人： Hamao Umezawa , Kenji Maeda , Shinichi Kondo
发明人： Hamao Umezawa , Kenji Maeda , Shinichi Kondo
IPC分类号： C07H19/23 , C07H19/052 , C07H19/16 , C07H19/18
CPC分类号： C07H19/16 , C07H19/052
摘要： This invention relates to a process for the preparation of coformycin, 3-(.beta.-D-ribofuranosyl)-6,7,8-trihydroimidazo[4,5-d][1,3]diazepin-8(R)-ol, through a synthetic route from a new derivative of 9-.beta.-D-ribofuranosyl-purine and other synthetic intermediates involved in the process and their preparation.
摘要翻译：本发明涉及一种制备共转霉素3-（β-D-呋喃核糖基）-6,7,8-三氢咪唑并[4,5-d] [1,3]二氮杂-8（R） - 醇的方法，通过合成路线从9β-D-呋喃核糖基嘌呤和其他合成中间体的新衍生物参与该方法及其制备。

87. 发明授权

US08777759B2 Universal joint and propeller shaft 有权
标题翻译：万向接头和传动轴
公开(公告)号：US08777759B2
公开(公告)日：2014-07-15
申请号：US13552088
申请日：2012-07-18
申请人： Keigo Yoshida , Hideaki Aoki , Hiromichi Komai , Shinichi Kondo , Yoshimichi Takano
发明人： Keigo Yoshida , Hideaki Aoki , Hiromichi Komai , Shinichi Kondo , Yoshimichi Takano
IPC分类号： F16D3/41
CPC分类号： F16D3/41 , F16N9/00
摘要： In a universal joint, a cross shaft member includes four shaft parts forming a cross-shape. Each of four bearing cups corresponding respectively to the shaft parts has a hollow-cylindrical shape having a bottom and is rotatably mounted to the corresponding shaft part through a roller disposed between an inner peripheral surface of the each bearing cup and an outer peripheral surface of the corresponding shaft part. Each bearing cup includes an inner bottom surface in sliding contact with a distal end surface of the corresponding shaft part, wherein the sliding contact is in an annular region encompassing a central axis of the corresponding shaft part. The distal end surface of each shaft part is formed with an annular groove encompassing the central axis of the first shaft part for storing oil.
摘要翻译：在万向接头中，横轴构件包括形成十字形的四个轴部。分别与轴部对应的四个轴承杯中的每一个都具有中空圆柱形，具有底部，并且通过设置在每个轴承杯的内周表面和滚子轴承的外周表面之间的辊可旋转地安装到相应的轴部分相应的轴部分。每个轴承杯包括与相应轴部分的远端表面滑动接触的内底表面，其中滑动接触处于包围相应轴部分的中心轴线的环形区域中。每个轴部分的远端表面形成有环形槽，该环形槽围绕第一轴部分的中心轴线，用于储存油。

88. 发明授权

US08504212B2 Controller and control techniques for windfarm 有权
标题翻译：风电场控制器和控制技术
公开(公告)号：US08504212B2
公开(公告)日：2013-08-06
申请号：US12857198
申请日：2010-08-16
申请人： Shinichi Kondo , Yasunori Ono , Noriyuki Uchiyama , Masaya Ichinose , Mitsugu Matsutake , Takashi Aihara
发明人： Shinichi Kondo , Yasunori Ono , Noriyuki Uchiyama , Masaya Ichinose , Mitsugu Matsutake , Takashi Aihara
IPC分类号： G05D11/00
CPC分类号： F03D7/047 , F03D7/0272 , F03D7/028 , F03D7/048 , F05B2260/821 , F05B2270/32 , F05B2270/321 , F05B2270/404 , Y02E10/723 , Y02E10/725
摘要： The disclosed windfarm control system comprising a windfarm and a central controller; the windfarm including plural wind power generators whose rotational speeds are variable, plural aerographs disposed in the vicinity of the wind power generators to measure the directions and powers of the wind at the sites of the generators, and plural local controllers disposed in the vicinity of the wind power generators to control the output of the wind power generators by controlling the rotational speeds of the generators; wherein the central controller calculats the control level which maintains the output of the windfarm constant for a predetermined time period and instructs the local controllers to control the rpm's of the wind power generators in accordance with the control level.
摘要翻译：所公开的风电场控制系统包括风电场和中央控制器; 所述风电场包括多个风力发电机，其转速可变，设置在所述风力发电机附近的多个风路机，以测量在所述发电机的位置处的风的方向和功率，以及设置在所述风力发电机附近的多个本地控制器风力发电机通过控制发电机的转速来控制风力发电机的输出; 其中中央控制器计算控制电平，该控制电平使风电场的输出保持恒定一段预定的时间段，并指示本地控制器根据控制电平来控制风力发电机的转速。

89. 发明授权

US08332077B2 Controller and control method for a wind farm including a plurality of wind turbine generators 有权
标题翻译：一种用于包括多个风力涡轮发电机的风力发电场的控制器和控制方法
公开(公告)号：US08332077B2
公开(公告)日：2012-12-11
申请号：US12570169
申请日：2009-09-30
申请人： Shinichi Kondo , Yasunori Ono , Noriyuki Uchiyama , Masaya Ichinose , Mitsugu Matsutake , Takashi Aihara
发明人： Shinichi Kondo , Yasunori Ono , Noriyuki Uchiyama , Masaya Ichinose , Mitsugu Matsutake , Takashi Aihara
IPC分类号： G05D5/00 , G05D9/00 , G05D11/00
CPC分类号： H02P9/04 , F03D7/047 , F03D7/048 , F05B2260/821 , F05B2270/32 , F05B2270/321 , H02P2101/15 , Y02E10/723
摘要： In a controller for a windfarm including a plurality of wind turbine generators controllable in rotation frequency and pith of blades of the wind turbine generators, coupled to a grid through a transmission line, an anemometer is provided to each wind turbine generator to transmits wind direction and wind speed data to a central controller which process the wind direction and wind speed data to transmit an output command each wind turbine generator. The central controller predicts, on the basis of the wind speed detected by the upstream wind turbine generator, variation in wind speed at other wind turbine generators to control the output of the windfarm. The output power may be limited or charging energy as rotation energy of blades and discharging the rotation energy as output power in addition to a battery unit for averaging.
摘要翻译：在包括风力涡轮发电机的旋转频率和叶片可控制的多个风力发电机的风力发电机的控制器中，风力涡轮发电机通过传输线耦合到电网，风力计被提供给每个风力涡轮发电机以传输风向和将风速数据传送到中央控制器，该中央控制器处理风向和风速数据，以传送每个风力涡轮发电机的输出指令。中央控制器根据上游风力发电机检测到的风速预测其他风力发电机的风速变化，以控制风电场的输出。除了用于平均的电池单元之外，输出功率可以被限制或者作为叶片的旋转能量的充电能量和作为输出功率的旋转能量的排出。

90. 发明授权

US08102223B2 Dielectric ceramic composition, multilayer complex electronic device, multilayer common mode filter, multilayer ceramic coil and multilayer ceramic capacitor 有权
标题翻译：介电陶瓷组合物，多层复合电子器件，多层共模滤波器，多层陶瓷线圈和多层陶瓷电容器
公开(公告)号：US08102223B2
公开(公告)日：2012-01-24
申请号：US12453422
申请日：2009-05-11
申请人： Shusaku Umemoto , Takashi Suzuki , Kouichi Kakuda , Hiroshi Momoi , Masaki Takahashi , Shinichi Kondo
发明人： Shusaku Umemoto , Takashi Suzuki , Kouichi Kakuda , Hiroshi Momoi , Masaki Takahashi , Shinichi Kondo
IPC分类号： H03H7/00 , C03C14/00 , C04B35/00 , H01F5/00 , H01G4/06
CPC分类号： C04B35/18 , C04B35/20 , C04B2235/3201 , C04B2235/3206 , C04B2235/3208 , C04B2235/3213 , C04B2235/3215 , C04B2235/3281 , C04B2235/3284 , C04B2235/3409 , C04B2235/3418 , C04B2235/365 , C04B2235/6562 , C04B2235/6565 , C04B2235/77 , C04B2235/785 , H01F5/003 , H01F17/0013 , H01F2017/0066 , H01F2017/0093 , H01G4/10 , H01G4/105 , H01G4/12 , H01G4/1209 , H03H7/0115 , H03H7/427 , H03H2001/0085 , H05K1/0306
摘要： A dielectric ceramic composition comprises as a main component, Cu oxide, Si oxide and one selected from the group consisting of Zn oxide alone and a combination of Mg oxide and Zn oxide, as a subcomponent, a glass component including B oxide and at least one selected from the group consisting of Si oxide, Ba oxide, Ca oxide, Sr oxide, Li oxide and Zn oxide, and having a glass softening point is 750° C. or less, wherein a content of said glass component is 1.5 to 15 wt % with respect to 100 wt % of said main component. According to the present invention, a dielectric ceramic composition can be provided which is available to be sintered at low temperature (for example, 950° C. or lower) while comparatively decreasing contents of a glass component, which shows good properties (specific permittivity, loss Q value and insulation resistance), and which is available to perform cofiring different materials.
摘要翻译：电介质陶瓷组合物作为主要成分包含Cu氧化物，Si氧化物和选自单独的Zn氧化物和Mg氧化物和Zn氧化物的组合的一种作为副成分，包括B氧化物的玻璃成分和至少一种选自由Si氧化物，Ba氧化物，CaO 2，Sr氧化物，Li氧化物和Zn氧化物组成的组，玻璃软化点为750℃以下，其中，所述玻璃成分的含量为1.5〜15重量％相对于100重量％的所述主要成分。根据本发明，可以提供一种电介质陶瓷组合物，其可以在低温（例如950℃或更低）下烧结，同时相对降低玻璃组分的含量，其显示出良好的性能（比介电常数，损耗Q值和绝缘电阻），并且可用于执行不同材料的共烧。

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