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    • 83. 发明申请
    • Haparin-Binding Protein Modified with Heparan Sulfate Sugar Chains, Process for Producing the Same and Pharmaceutical Compositions Containing the Same
    • 用硫酸肝素糖链修饰的Haparin结合蛋白,其制备方法和含有其的药物组合物
    • US20080119403A1
    • 2008-05-22
    • US11547346
    • 2005-03-31
    • Toru ImamuraMasahiro AsadaMasashi Suzuki
    • Toru ImamuraMasahiro AsadaMasashi Suzuki
    • A61K31/70C07K16/00A61P43/00C07H21/04C12P21/04
    • C07K14/501A61K38/00C07K2319/35
    • A heparin-binding protein having covalently bonded heparan sulfate sugar chains within its molecule is produced by ligating a cDNA encoding a peptide which can be modified with heparan sulfate sugar chains selectively to a cDNA encoding a heparin-binding protein and producing in an animal cell the gene product of the resultant ligated cDNA. This heparan sulfate sugar chain-modified heparin-binding protein is functionalized by covalently bonding thereto glycosaminoglycan sugar chains containing little chondroitin sulfate. For example, this heparin-binding protein is excellent in stabilities, such as thermostability, acid resistance, alkali resistance and in vivo stability. Further, the heparan sulfate sugar chain-modified heparin-binding protein is effective in cell proliferation and tissue regeneration, and has effect of regulating the physiological functions of FGFs. Thus, this heparin-binding protein is extremely useful as a medicine for preventing or treating various FGF-related diseases.
    • 在其分子内具有共价键合的硫酸肝素糖链的肝素结合蛋白是通过将编码可以与硫酸肝素糖链修饰的肽选择性地编码到编码肝素结合蛋白的cDNA并在动物细胞中产生的cDNA来产生的 所得连接的cDNA的基因产物。 这种硫酸乙酰肝素糖链修饰的肝素结合蛋白通过共价键合含有少量硫酸软骨素的糖胺聚糖糖链来官能化。 例如,该肝素结合蛋白质的稳定性优异,例如耐热性,耐酸性,耐碱性和体内稳定性。 此外,硫酸乙酰肝素糖链修饰的肝素结合蛋白对细胞增殖和组织再生有效,具有调节FGFs生理功能的作用。 因此,该肝素结合蛋白作为预防或治疗各种FGF相关疾病的药物是非常有用的。
    • 86. 发明申请
    • Information processing system, printing device and content access system
    • 信息处理系统,打印设备和内容访问系统
    • US20070127067A1
    • 2007-06-07
    • US11586582
    • 2006-10-26
    • Satoshi WatanabeKazuma AokiMasashi SuzukiKiyotaka OharaMakoto Matsuda
    • Satoshi WatanabeKazuma AokiMasashi SuzukiKiyotaka OharaMakoto Matsuda
    • G06F3/12
    • G06F3/1265G06F3/1204G06F3/1287
    • There is provided an information processing system, which comprises a printing unit, a link information print control unit configured such that when first contents which has a first address and contains an object to which a second address is assigned as a link target address are printed, it causes the printing unit to print link information indicating that the first address is a link source address and the second address is the link target address, a link information obtaining unit configured to obtain the link information printed by the printing unit, a second content access unit configured to access second contents to which the second address is assigned in accordance with the link information, and a link source address notification unit configured to notify the link target address of information on the first address in response to execution of access by the second content access unit.
    • 提供了一种信息处理系统,其包括打印单元,链接信息打印控制单元,其被配置成当具有第一地址的第一内容包含被分配了第二地址的对象作为链接目标地址时, 使打印单元打印指示第一地址是链接源地址的链接信息,并且第二地址是链接目标地址;链接信息获取单元,被配置为获得由打印单元打印的链接信息,第二内容访问 被配置为根据所述链接信息访问分配了所述第二地址的第二内容的单元,以及响应于所述第二内容的访问的执行而通知所述链接目标地址关于所述第一地址的信息的链接源地址通知单元 存取单元
    • 90. 发明授权
    • Autochoke controller
    • 自动调节控制器
    • US07128036B2
    • 2006-10-31
    • US10477380
    • 2002-10-18
    • Masashi Suzuki
    • Masashi Suzuki
    • F02D9/10F02D41/06F02M1/10
    • F02M1/10F02M1/046
    • An auto-choke control device maintains good startability at the time of restarting at high temperature without need of a thermostat specific for an auto-choke. An engine temperature detection device is drivably controlled by a control circuit in response to the engine temperature. A switching detection circuit detects ON or OFF operation of a main switch connected to the control circuit. A self-hold circuit automatically holds power to the control circuit when the main switch is changed from an ON state to an OFF state.
    • 自动扼流器控制装置在高温重启时保持良好的起动性,而不需要专用于自动扼流圈的恒温器。 发动机温度检测装置响应于发动机温度由控制电路驱动地控制。 切换检测电路检测与控制电路连接的主开关的接通或断开操作。 当主开关从ON状态变为OFF状态时,自保持电路自动保持控制电路的电源。