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81. 发明申请

US20110224959A1 GAS TURBINE MODEL AND A METHOD FOR THE MODELING OF A GAS TURBINE 有权
标题翻译：气体涡轮机模型和气体涡轮机建模方法
公开(公告)号：US20110224959A1
公开(公告)日：2011-09-15
申请号：US13081007
申请日：2011-04-06
申请人： Xiao-Yi Zhang , Anton Nemet
发明人： Xiao-Yi Zhang , Anton Nemet
IPC分类号： G06F17/10 , G06G7/64
CPC分类号： G05B17/02
摘要： Numerical gas turbine models permit transient modeling with high precision and at the same time numerically efficient processes for modeling a gas turbine. A gas turbine model includes a plurality of sub models. These sub models are either purely dynamic or static, which allows significant simplifications in the numerical solution of the overall model. System parts, which simulate the effects of volumes, metal masses, of actuators, and of measuring systems are regarded as dynamic. The remaining system parts are regarded as static over a time characteristic.
摘要翻译：数值燃气轮机模型允许高精度的瞬态建模，同时对燃气轮机进行建模的数值有效的过程。燃气轮机模型包括多个子模型。这些子模型是纯动态的或静态的，这允许在整个模型的数值解中显着简化。模拟体积，金属质量，执行器和测量系统的影响的系统部件被认为是动态的。剩余的系统部件在时间特性上被视为静态的。

82. 发明授权

US07935659B2 Multiplexed assays using encoded solid supports 失效
标题翻译：使用编码的固体支持物的多重测定
公开(公告)号：US07935659B2
公开(公告)日：2011-05-03
申请号：US11011452
申请日：2004-12-14
申请人： Michael P. Nova , Andrew E. Senyei , Zahra Parandoosh , Gary S. David , Xiao-Yi Xiao
发明人： Michael P. Nova , Andrew E. Senyei , Zahra Parandoosh , Gary S. David , Xiao-Yi Xiao
IPC分类号： C40B50/16 , C40B50/18
CPC分类号： C40B30/04 , B01J19/0046 , B01J2219/00295 , B01J2219/00299 , B01J2219/00308 , B01J2219/00333 , B01J2219/00344 , B01J2219/00461 , B01J2219/00463 , B01J2219/005 , B01J2219/00502 , B01J2219/0054 , B01J2219/00542 , B01J2219/00547 , B01J2219/00549 , B01J2219/00551 , B01J2219/0056 , B01J2219/00563 , B01J2219/00567 , B01J2219/00569 , B01J2219/00585 , B01J2219/0059 , B01J2219/00592 , B01J2219/00596 , B01J2219/00689 , B01J2219/00695 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01L3/5027 , B01L3/502707 , B01L2300/0609 , B82Y10/00 , C07K1/00 , C07K1/04 , C07K1/047 , C40B40/06 , C40B40/10 , C40B60/08 , C40B60/14 , C40B70/00 , G01N35/00732 , G01N35/00871 , G01N2015/149 , G01N2035/00782 , G11C13/0014 , G11C13/0019 , G11C13/025
摘要： Combinations, called matrices with memories, of matrix materials with remotely addressable or remotely programmable recording devices that contain at least one data storage unit are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix materials may additionally include fluophors or other luminescent moieties to produce luminescing matrices with memories. The data storage units are non-volatile antifuse memories or volatile memories, such as EEPROMS, DRAMS or flash memory. By virtue of this combination, molecules and biological particles, such as phage and viral particles and cells, that are in proximity or in physical contact with the matrix combination can be labeled by programming the memory with identifying information and can be identified by retrieving the stored information. Combinations of matrix materials, memories, and linked molecules and biological materials are also provided. The combinations have a multiplicity of applications, including combinatorial chemistry, isolation and purification of target macromolecules, capture and detection of macromolecules for analytical purposes, selective removal of contaminants, enzymatic catalysis, cell sorting, drug delivery, chemical modification and other uses. Methods for electronically tagging molecules, biological particles and matrix support materials, immunoassays, receptor binding assays, scintillation proximity assays, non-radioactive proximity assays, and other methods are also provided.
摘要翻译：提供了具有包含至少一个数据存储单元的具有可远程寻址或远程可编程记录设备的矩阵材料的具有存储器的组合。基质材料是在固相化学和生物化学合成，免疫测定和杂交反应中用作载体的基质材料。基质材料还可以包括荧光体或其它发光部分以产生具有记忆的发光基质。数据存储单元是非易失性反熔丝存储器或易失性存储器，例如EEPROMS，DRAMS或闪存。通过这种组合，可以通过用识别信息对存储器进行编程来标记与基质组合接近或物理接触的分子和生物颗粒，例如噬菌体和病毒颗粒和细胞，并且可以通过检索存储的信息。还提供了基质材料，记忆和连接分子和生物材料的组合。这些组合具有多种应用，包括组合化学，目标大分子的分离和纯化，用于分析目的的大分子的捕获和检测，污染物的选择性去除，酶催化，细胞分选，药物递送，化学修饰和其它用途。还提供了用于电子标记分子，生物颗粒和基质支持材料的方法，免疫测定，受体结合测定，闪烁亲近测定，非放射性邻近测定和其它方法。

83. 发明授权

US07830916B2 Cyclic bandwidth allocation method with HARQ enabled 有权
标题翻译：循环带宽分配方法，启用HARQ
公开(公告)号：US07830916B2
公开(公告)日：2010-11-09
申请号：US12283447
申请日：2008-09-12
申请人： Xin Qi , Xiao Yi Wang
发明人： Xin Qi , Xiao Yi Wang
IPC分类号： H04J3/16
CPC分类号： H04L1/1822 , H04L1/1812 , H04L5/0007 , H04L5/0037 , H04L5/0053 , H04L5/006 , H04L5/0082 , H04L5/0085 , H04L5/0092 , H04W72/04
摘要： A method is described which includes allocating transmission resources for transmitting data packets. The allocation of transmission resources includes a periodic allocation of the transmission resources that is applicable to a plurality of frames. The allocation of transmission resources includes an allocation of transmission resources for a first transmission of each HARQ process during the plurality of frames. The method includes receiving an indication of an allocation of transmission resources for data packets in a plurality of frames. Receiving and/or transmitting packets during the plurality of frames using the allocation of transmission resources is also included in the method. The frames in the plurality of frames may include a compressed MAC header. Apparatus and computer programs are also described.
摘要翻译：描述了一种方法，其包括分配用于发送数据分组的传输资源。传输资源的分配包括适用于多个帧的传输资源的周期性分配。传输资源的分配包括在多个帧期间对每个HARQ进程的第一次传输的传输资源的分配。该方法包括接收多个帧中的数据分组的传输资源的分配指示。在该多个帧中使用传输资源的分配来接收和/或传送分组也包括在该方法中。多个帧中的帧可以包括压缩的MAC报头。还描述了装置和计算机程序。

84. 发明授权

US07790734B2 Dipeptidyl peptidase inhibitors 有权
标题翻译：二肽基肽酶抑制剂
公开(公告)号：US07790734B2
公开(公告)日：2010-09-07
申请号：US10934326
申请日：2004-09-02
申请人： Sheldon X. Cao , Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
发明人： Sheldon X. Cao , Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
IPC分类号： C07D239/47 , C07D239/48 , C07D403/12 , A61K31/505
CPC分类号： C07D401/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
摘要翻译：提供化合物，药物，试剂盒和方法用于包含式I的DPP-IV抑制剂：其中取代基如本文所述。

85. 发明授权

US07772245B2 Inhibitors of histone deacetylase 有权
标题翻译：组蛋白脱乙酰酶抑制剂
公开(公告)号：US07772245B2
公开(公告)日：2010-08-10
申请号：US11354594
申请日：2006-02-14
申请人： Sampath K. Anandan , Xiao-Yi Xiao , John S. Ward , Dinesh V. Patel
发明人： Sampath K. Anandan , Xiao-Yi Xiao , John S. Ward , Dinesh V. Patel
IPC分类号： A61K31/506 , C07D471/02
CPC分类号： C07D471/04 , C07D401/04 , C07D487/04 , C07D491/04 , C07D495/04
摘要： Disclosed are compounds of formula I that inhibit histone deacetylase (HDAC) enzymatic activity, pharmaceutical compositions comprising such compounds, as well as methods to treat conditions, particularly proliferative conditions, mediated at least in part by HDAC, wherein A, W, W1, W2, Ar2, and G are described herein.
摘要翻译：公开了抑制组蛋白脱乙酰酶（HDAC）酶活性的式I化合物，包含这些化合物的药物组合物以及至少部分由HDAC介导的条件，特别是增殖性病症的方法，其中A，W，W1，W2 ，Ar2和G。

86. 发明申请

US20090264422A1 METHOD OF TREATING DISEASE STATES USING SUBSTITUTED PYRAZOLE COMPOUNDS 有权
标题翻译：使用取代的吡唑化合物治疗疾病状态的方法
公开(公告)号：US20090264422A1
公开(公告)日：2009-10-22
申请号：US12494677
申请日：2009-06-30
申请人： Xiao-Yi Xiao , Dinish V. Patel , John S. Ward , Mark R. Bray , Gregory E. Agoston , Anthony M. Treston
发明人： Xiao-Yi Xiao , Dinish V. Patel , John S. Ward , Mark R. Bray , Gregory E. Agoston , Anthony M. Treston
IPC分类号： A61K31/541 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P35/00 , A61P29/00 , A61P3/10 , A61P25/00
CPC分类号： C07D401/14 , A61K31/506 , A61K31/5377 , A61K31/541 , C07D403/12 , C07D403/14 , C07D405/14 , C07D471/04 , C07D487/04
摘要： Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.
摘要翻译：公开了蛋白激酶抑制剂，包含这种抑制剂的组合物及其使用方法。更具体地，公开了Aurora A（Aurora-2）蛋白激酶的抑制剂。还公开了治疗与蛋白激酶相关疾病，特别是与Aurora-2相关的疾病如癌症的方法。

87. 发明授权

US07455862B2 Herbal compositions useful in cancer treatment 有权
标题翻译：草药组合物可用于癌症治疗
公开(公告)号：US07455862B2
公开(公告)日：2008-11-25
申请号：US11088022
申请日：2005-03-23
申请人： Wah Keung Karl Tsim , Xiao Yi Li
发明人： Wah Keung Karl Tsim , Xiao Yi Li
IPC分类号： A61K36/906 , A61K36/00
CPC分类号： A61K36/8969 , A61K9/08 , A61K9/19 , A61K36/185 , A61K36/30 , A61K36/484 , A61K36/489 , A61K36/74 , A61K36/815 , A61K36/888 , A61K36/8888 , A61K36/8984 , A61K36/9066 , A61K2300/00
摘要： A herbal composition containing Curcumae kwangsiensis (Ezhu), Herba Dendrobii nobile Lindl. (Shihu), Rhizoma Pinelliae preparatum (Fabanxia), Rhizoma Typhonii (Baifuzi) and other optional herbs. The composition can be processed into a form for administering to human patients with a cancerous disease for improving their health.
摘要翻译：含有卷心菜（Ezhu），草本植物枸杞子的草药成分。（Shihu），Pinelliae preparatum（Fabanxia），Typifonii（Baifuzi）等任选草药。组合物可以加工成用于给患有癌性疾病的人患者施用以改善其健康的形式。

88. 发明申请

US20050137232A1 Histone deacetylase inhibitors 失效
标题翻译：组蛋白脱乙酰酶抑制剂
公开(公告)号：US20050137232A1
公开(公告)日：2005-06-23
申请号：US10803580
申请日：2004-03-17
申请人： Jerome Bressi , Jason Brown , Sheldon Cao , Anthony Gangloff , Andrew Jennings , Jeffrey Stafford , Phong Vu , Xiao-Yi Xiao
发明人： Jerome Bressi , Jason Brown , Sheldon Cao , Anthony Gangloff , Andrew Jennings , Jeffrey Stafford , Phong Vu , Xiao-Yi Xiao
IPC分类号： A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/535 , C07D235/18 , C07D413/02 , C07D417/02 , C07D43/02
CPC分类号： C07D235/18 , C07D401/04 , C07D401/06 , C07D403/06 , C07D403/10
摘要： Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
摘要翻译：可用于抑制组氨酸脱乙酰酶的化合物，其具有式<？in-line-formula description =“In-line Formulas”end =“lead”？> ZQLM或ZLM <？in-line-formula description =“In-line 式“end =”tail“？>其中M是能够与脱乙酰酶催化部位和/或金属离子络合的取代基; L是在M取代基和化合物的其余部分之间分离0-10个原子之间的取代基; Z和Q如本文所定义。

89. 发明申请

US20140223595A1 DROUGHT TOLERANT PLANTS AND RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING DTP6 POLYPEPTIDES 有权
标题翻译：耐旱植物及相关建议及涉及编码DTP6多肽的基因的方法
公开(公告)号：US20140223595A1
公开(公告)日：2014-08-07
申请号：US13877814
申请日：2011-10-28
申请人： Stephen M. Allen , Jason L. Brothers , Krupa Deshmukh , Honor Renee Lafitte , Xiao-Yi Li , Cheng Lu , Stanley Luck , Jeffrey Mullen , Hajime Sakai , James J. Saylor , Scott V. Tingey , Robert Wayne Williams
发明人： Stephen M. Allen , Jason L. Brothers , Krupa Deshmukh , Honor Renee Lafitte , Xiao-Yi Li , Cheng Lu , Stanley Luck , Jeffrey Mullen , Hajime Sakai , James J. Saylor , Scott V. Tingey , Robert Wayne Williams
IPC分类号： C12N15/82 , G06F19/20
CPC分类号： C12N15/8274 , A01H5/10 , C12N15/8261 , C12N15/8273 , G06F19/20
摘要： Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP6 polypeptide.
摘要翻译：用于赋予耐旱性的分离的多核苷酸和多肽和重组DNA构建体，包含这些重组DNA构建体的组合物（例如植物或种子），以及利用这些重组DNA构建体的方法。重组DNA构建体包含可操作地连接于在植物中有功能的启动子的多核苷酸，其中所述多核苷酸编码DTP6多肽。

90. 发明申请

US20130345178A1 8-AZA Tetracycline Compounds 有权
标题翻译： 8-AZA四环素类化合物
公开(公告)号：US20130345178A1
公开(公告)日：2013-12-26
申请号：US13731753
申请日：2012-12-31
申请人： Roger B. Clark , Minsheng He , Louis Plamondon , Xiao-Yi Xiao , Magnus P. Ronn
发明人： Roger B. Clark , Minsheng He , Louis Plamondon , Xiao-Yi Xiao , Magnus P. Ronn
IPC分类号： C07D221/18
CPC分类号： C07D221/18
摘要： The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula I and its therapeutic use.
摘要翻译：本发明涉及由结构式（I）表示的化合物或其药学上可接受的盐。结构式I的变量在本文中定义。还描述了包含结构式I的化合物及其治疗用途的药物组合物。

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