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81. 发明授权

EP0531991B1 Method for preparing chitosan 失效
标题翻译：一种用于制备脱乙酰壳多糖的方法
公开(公告)号：EP0531991B1
公开(公告)日：1998-07-15
申请号：EP92115491.0
申请日：1992-09-10
申请人： Shin-Etsu Chemical Co., Ltd. , THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： Park, Okmi, c/o SHIN-ETSU CHEMICAL CO., LTD. , Miyoshi, Hiroshi, c/o CORPORATE RESEARCH CENTER , Watanabe, Jun, c/o CORPORATE RESEARCH CENTER , Chiba, Tohru, c/o CORPORATE RESEARCH CENTER , Endo, Isao, c/o THE INSTITUE OF PHYSICAL
IPC分类号： C12P19/04
CPC分类号： C12P19/26 , Y10S435/912

82. 发明公开

EP0739856A2 A silica-surfactant nanocomposite and its production process 失效
标题翻译： Kieselsäuretensidnanokomposit和Verfahren zu seiner Herstellung
公开(公告)号：EP0739856A2
公开(公告)日：1996-10-30
申请号：EP96250091.4
申请日：1996-04-24
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： Ogawa, Makoto , Sasabe, Hiroyuki
IPC分类号： C01B37/02 , B01J20/10
CPC分类号： C01B37/02 , B01J20/103
摘要： A periodic silica-surfactant nanocomposite, of which crystal structure belongs to hexagonal system, has aggregated cylindrical micelle rods formed by surfactant surrounded by silica layers is provided. A periodic silica porous material has channels sized in 1-2 nm, with equal to or more than 1,000 m 2 /g as BET surface area is also provided by calcining the nanocomposite. A production process of the nanocomposites is further provided, and the process comprising steps of hydrolyzing tetraalkoxysilane under acidic condition to obtain hydrolysates, mixing surfactants and the hydrolysates obtained, coating the mixed solution on the substrate, and drying the coated solution.
Such nanocomposites are obtained conveniently, and they may be formed as transparent film or gel-like lumps. Since the silica porous material has high specific surface area, it is available for optical functional materials, and so forth.
摘要翻译：提供晶体结构属于六方晶系的周期性二氧化硅 - 表面活性剂纳米复合材料，具有由二氧化硅层包围的表面形成的聚集的圆柱形胶束。周期性二氧化硅多孔材料的通道尺寸为1-2nm，等于或大于1000m 2 / g，因为BET表面积也通过煅烧纳米复合材料而提供。进一步提供了纳米复合材料的制造方法，该方法包括在酸性条件下水解四烷氧基硅烷以获得水解物，混合表面活性剂和所得水解产物，将混合溶液涂布在基材上，干燥涂布溶液的步骤。这种纳米复合材料方便地得到，它们可以形成为透明膜或凝胶状团块。由于二氧化硅多孔材料具有高比表面积，因此可用于光学功能材料等。

83. 发明公开

EP0541310A3 Magnetoencephalograph 失效
标题翻译：磁波
公开(公告)号：EP0541310A3
公开(公告)日：1993-12-22
申请号：EP92309992.3
申请日：1992-10-30
申请人： MITSUI MINING & SMELTING CO., LTD. , THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： Ohta, Hiroshi , Hoshino, Kazutomo,
IPC分类号： G01R33/035 , A61B5/00 , H05K9/00
CPC分类号： A61B5/04008 , G01R33/035
摘要： A magnetoencephalograph comprising an oxide superconductor magnetic shield (3) and a cryostat (4) for cooling the magnetic shield vessel, a multichannel SQUID (1) and a cryostat (2) for cooling the SQUID inserted together in the magnetic shield vessel from one end of the magnetic shield vessel, a magnetic-field detection unit (5) situated in the vessel for detecting magnetic fields, and a coupling portion (6) for coupling the SQUID and the magnetic-field detection unit with respect to the signals, and the SQUID and the magnetic-field detection unit being detachable. The magnetoencephalograph makes possible detection of the very weak magnetic fields from the human brain and therewith reduction of the diameter of the opening of the magnetic shield vessel for inserting the SQUID. The reduction of the diameter of the SQUID opening in turn makes it possible to reduce the length of the magnetic shield vessel preserving a high shielding effect of the magnetic shield vessel because of the relationship L/D. The magnetic shield vessel is thus reduced to a practical size easy to handle and fabricatable at a low cost.
摘要翻译：包括用于冷却磁屏蔽容器的氧化物超导体磁屏蔽（3）和低温恒温器（4）的脑磁图，多通道SQUID（1）和低温恒温器（2），用于将插入在磁屏蔽容器中的SQUID从一端的磁屏蔽容器的磁场检测单元（5），用于检测磁场的磁场检测单元（5），以及用于相对于信号耦合SQUID和磁场检测单元的耦合部分（6），以及 SQUID和磁场检测单元可拆卸。脑电图可以检测来自人脑的非常弱的磁场，从而减少用于插入SQUID的磁屏蔽容器的开口的直径。因此，由于L / D的关系，SQUID开口的直径的减小又可以减小磁屏蔽容器的长度，从而保持磁屏蔽容器的高屏蔽效果。因此，磁屏蔽容器被减少到易于处理并且可以以低成本制造的实际尺寸。

84. 发明公开

EP0434375A1 Method of producing brassinosteroids 失效
标题翻译： Methode zur Poduktion von Brassinosteroiden。
公开(公告)号：EP0434375A1
公开(公告)日：1991-06-26
申请号：EP90313860.0
申请日：1990-12-18
申请人： SOMAR CORPORATION , THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： Saimoto, Hiroshi , Otsuka, Masako , Yamamoto, Mifumi , Kawashima, Masao , Fujioka, Shozo , Sakurai, Akira , Yokota, Takao , Shono, Kunihiko
IPC分类号： C12P33/00
CPC分类号： C12P33/00
摘要： A method of producing a brassinosteroid is disclosed, wherein crown gall cells capable of producing the brassinosteroid are cultured in a culture medium in the presence of a cultivation aid selected from auxins, sterols, squalene, casamino acid and mixtures thereof.
摘要翻译：公开了一种生产油菜素甾醇的方法，其中能够产生油菜素甾醇的冠胆细胞在选自生长素，甾醇，角鲨烯，酪蛋白氨基酸及其混合物的培养助剂存在下在培养基中培养。

85. 发明公开

EP1674565A2 Method for enhancing enzyme activity at elevated temperature 失效
标题翻译：在升高的温度增加的酶活性的方法
公开(公告)号：EP1674565A2
公开(公告)日：2006-06-28
申请号：EP06007353.3
申请日：1997-07-24
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH , Hayashizaki, Yoshihide
发明人： Hayashizaki, Yoshihide
IPC分类号： C12N9/96 , C12N9/12 , C12Q1/68
CPC分类号： C12N9/1276 , C12N9/1252 , C12N9/22 , C12N9/96
摘要： A method for enhancing activity of enzyme at an elevated temperature which comprises adding a substance exhibiting chaperone function such as a saccharide to a reaction mixture containing the enzyme. The method can improve activity of enzymes more easily and more effectively and hence afford increased enzyme activity at an elevated temperature.

86. 发明授权

EP0821059B8 Method for reverse transcription 失效
标题翻译：一种用于反转录方法
公开(公告)号：EP0821059B8
公开(公告)日：2006-03-08
申请号：EP97112672.7
申请日：1997-07-24
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH , Kabushiki Kaisha Dnaform
发明人： Hayashizaki, Yoshihide Tsukuba Life Science Center
IPC分类号： C12N9/12 , C12Q1/68 , C12N15/10 , C07H21/02 , C12N9/96
CPC分类号： C12N15/1096 , C12Q1/6844 , C12Q2527/101 , C12Q2521/107 , C12Q2527/125

87. 发明公开

EP1424579A1 Illumination apparatus for microscope and image processing apparatus using the same 审中-公开
标题翻译： BeleuchtungsvorrichtungfürMikroskop und damit versehene Bildverarbeitungsvorrichtung
公开(公告)号：EP1424579A1
公开(公告)日：2004-06-02
申请号：EP03026559.9
申请日：2003-11-18
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH , Olympus Corporation
发明人： Miyawaki, Atsushi Inst. Physical Chemical Research , Fukano, Takashi Inst. Physical Chemical Research , Aono, Yasushi, Int.Property Department
IPC分类号： G02B21/00 , G02B21/06 , G02B21/16 , G02B21/36
CPC分类号： G02B21/06 , G02B21/16 , G02B21/365
摘要： An illumination apparatus for a microscope and an image processing apparatus using the illumination apparatus include a light source, a semi-transmissive mirror splitting a light beam from the light source into two beams of the first and second irradiation light, two excitation filters selecting the wavelengths of the first and second irradiation light, a semi-transmissive mirror synthesizing individual beams of the first and second irradiation light whose wavelengths are selected, into a single beam, a dichroic mirror directing a light beam synthesized by the semi-transmissive mirror toward a specimen and transmitting light from the specimen, an objective lens, cameras imaging fluorescent light from the specimen after being separated into fluorescent light excited by the first and second wavelengths, and an image processing section processing fluorescent images formed by imaging elements.
摘要翻译：用于显微镜的照明装置和使用该照明装置的图像处理装置包括光源，将来自光源的光束分成两束第一和第二照射光的半透射镜，两个激发滤光器选择波长第一和第二照射光的第一和第二照射光的半透射镜将将波长选择的第一和第二照射光的各个光束合成为单个光束，将由半透射镜合成的光束引向样品的二向色镜以及透射来自所述样本的物体，物镜，将被分离成由所述第一和第二波长激发的荧光后的荧光从所述检体成像的照相机，以及处理由成像元件形成的荧光图像的图像处理部。

88. 发明授权

EP0916342B1 A medicament for treating obesity and improving lipid metabolism 有权
标题翻译：一种药物，用于治疗肥胖和改善脂质代谢
公开(公告)号：EP0916342B1
公开(公告)日：2003-10-22
申请号：EP98121049.5
申请日：1998-11-06
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH , Suzuki, Kunio
发明人： Suzuki, Kunio , Shimizu, Takeshi, c/o The Institute of Physical , Nakata, Tadashi, c/o The Institute of Physical
IPC分类号： A61K31/575 , A23K1/165 , A23L1/30 , A61P3/04 , A61P3/06
CPC分类号： A61K31/575 , Y10S514/824 , Y10S514/909

89. 发明授权

EP0785278B1 METHOD FOR DETERMINING DNA NUCLEOTIDE SEQUENCE 失效
标题翻译： PROCEDURE用于确定DNA核苷酸序列
公开(公告)号：EP0785278B1
公开(公告)日：2003-02-05
申请号：EP95936097.5
申请日：1995-11-06
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： HAYASHIZAKI, Yoshihide The Institute of Physical , SASAKI, Nobuya The Institute of Physical
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6869 , C12Q2525/143 , C12Q2521/119
摘要： A method of DNA sequencing for determining the base sequence of a DNA product amplified by the polymerase chain reaction without removing a primer and/or 2'-deoxyribonucleoside 5'-triphosphate and/or a derivative thereof, which method comprises preparing a nucleic acid transcription product by the reaction of ribonucleoside 5'-triphosphates comprising ATP, GTP, CTP, UTP or derivatives thereof with one or more 3'-deoxyribonucleotide 5'-triphosphates comprising 3'-dATP, 3'-dGTP, 3'-dCTP, 3'-dUTP and derivatives thereof in the presence of an RNA polymerase and the abovementioned amplified DNA product containing the promoter sequence for the RNA polymerase, separating the transcription product thus prepared, and reading the sequence of the nucleic acids in the separated fraction.

90. 发明公开

EP0898247A3 Method of synthesizing measurement data of free-form surface 审中-公开
标题翻译：一种用于自由形式表面的测量数据的准备处理
公开(公告)号：EP0898247A3
公开(公告)日：2002-12-04
申请号：EP98115196.2
申请日：1998-08-12
申请人： THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
发明人： Kase, Kiwamu
IPC分类号： G06T17/30
CPC分类号： G06T17/30 , Y02P90/265
摘要： (a) A surface shape of an object 1 is measured from different positions and/or different directions and plural partial measurement data 2 including common part 1a is obtained. (b) A parametric surface showing the surface shape of each measurement range is formed from the data. (c) A plurality of sampling points are set at a predetermined pitch in the common part and the Gaussian curvature K and/or an average curvature H are calculated from the principal curvatures (κ 1 ,κ 2 ) in the points. (d) Three or more characteristic points are selected in accordance with the order from larger absolute values of K or H in the common part and a normal vector of a plane constructed by three points among the points is calculated. (e) The common parts are made coincide with each other by moving the parametric surfaces so as to coincide the three characteristic points with each other and to coincide the directions of the normal vectors with each other. Consequently, the synthesis data can be formed from the partial measurement data obtained from the free-form surface.

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