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81. 发明申请

WO2010109021A2 IMPROVEMENTS IN IMPLANTABLE DEVICES 审中-公开
标题翻译：可植入装置的改进
公开(公告)号：WO2010109021A2
公开(公告)日：2010-09-30
申请号：PCT/EP2010/054052
申请日：2010-03-26
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , O'BRIEN, Timothy , GREISER, Udo , SHARIF, Faisal , HYNES, Sean , CROWLEY, Jim
发明人： O'BRIEN, Timothy , GREISER, Udo , SHARIF, Faisal , HYNES, Sean , CROWLEY, Jim
IPC分类号： A61L27/22
CPC分类号： A61L27/54 , A61K9/127 , A61K9/1272 , A61K47/6957 , A61L29/16 , A61L31/16 , A61L2300/258 , A61L2300/626
摘要： The present invention relates to implantable devices, which are coated or coatable with liposomes. The present invention further relates to liposomes encapsulating nucleic acids termed lipoplexes, to methods for the manufacture and coating of such implantable devices, and to the use of such implantable devices to improve treatment of patients with coronary artery disease or other vascular diseases and cancers.
摘要翻译：本发明涉及可与脂质体包被或可涂覆的可植入装置。本发明还涉及包封称为脂质复合物的核酸的脂质体，这种可植入装置的制造和涂覆方法，以及使用这种可植入装置来改善冠状动脉疾病或其它血管疾病和癌症患者的治疗。

82. 发明申请

WO2009150242A9 P2/P2A/P2B GENE SEQUENCES AS DIAGNOSTIC TARGETS FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES 审中-公开
公开(公告)号：WO2009150242A9
公开(公告)日：2009-12-17
申请号：PCT/EP2009/057338
申请日：2009-06-15
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , BARRY, Thomas, Gerard , SMITH, Terry, James , JANKIEWICZ, Marcin , O'CONNOR, Louise , TUITE, Nina , LAHIFF, Sinead , MAHER, Majella
发明人： BARRY, Thomas, Gerard , SMITH, Terry, James , JANKIEWICZ, Marcin , O'CONNOR, Louise , TUITE, Nina , LAHIFF, Sinead , MAHER, Majella
IPC分类号： C12Q1/68
摘要： The present invention relates to nucleic acid primers and probes to detect one or more fungal and yeast species. More specifically the invention relates to the P2, P2A and P2B gene sequences (also known as 60S acidic ribosomal protein P2, RLA-2-ASPFU, Allergen ASP f8 or Afp2), the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/ or discriminate fungal and yeast species.

83. 发明申请

WO2009150241A2 EIF2γ GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES 审中-公开
标题翻译：的eIF2？基因作为鉴定真菌和YEAST物种的诊断目标
公开(公告)号：WO2009150241A2
公开(公告)日：2009-12-17
申请号：PCT/EP2009/057337
申请日：2009-06-15
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , BARRY, Thomas Gerard , MAHER, Majella , SMTH, Terry James , MARCIN, Jankiewicz , O'CONNOR, Louise , TUITE, Nina , LAHIFF, Sinead
发明人： BARRY, Thomas Gerard , MAHER, Majella , SMTH, Terry James , MARCIN, Jankiewicz , O'CONNOR, Louise , TUITE, Nina , LAHIFF, Sinead
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895
摘要： The current invention relates to a diagnostic kit for a yeast or fungal species comprising at least one oligonucleotide probe capable of binding to at least a portion of the eIF2y gene or its corresponding mRNA.
摘要翻译：本发明涉及用于酵母或真菌物质的诊断试剂盒，其包含能够结合至少一部分eIF2y基因或其相应mRNA的至少一种寡核苷酸探针。

84. 发明申请

WO2009043856A2 MODULATION OF TISSUE FATTY ACID COMPOSITION OF A HOST BY HUMAN GUT BACTERIA 审中-公开
标题翻译：人类细菌细菌的组织脂肪酸组成的调节
公开(公告)号：WO2009043856A2
公开(公告)日：2009-04-09
申请号：PCT/EP2008/063106
申请日：2008-09-30
申请人： UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK , TEAGASC, - The Agriculture and Food Development Authority , ALIMENTARY HEALTH LTD. , O'MAHONY, Liam , SHANAHAN, Fergus , QUIGLEY, Eamonn , ROSS, Paul , STANTON, Catherine
发明人： O'MAHONY, Liam , SHANAHAN, Fergus , QUIGLEY, Eamonn , ROSS, Paul , STANTON, Catherine
IPC分类号： A61K35/74 , C12P7/64 , A23L1/30 , A61P25/28 , A61P1/00 , A61P17/00
CPC分类号： C12N1/20 , A23L33/135 , A61K31/201 , A61K35/74 , A61K35/744 , A61K35/745 , A61K35/747 , C12P7/6427 , C12P7/6472 , C12R1/01
摘要： The current invention provides use of a CLA -producing bacterium for the in viv o conversion in the gut of polyunsaturated fatty acids to CLA. The CLA- producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria.
摘要翻译：本发明提供了用于在多不饱和脂肪酸肠中向CLA转化的CLA产生细菌的用途。 CLA产生细菌选自丙酸杆菌属，乳酸杆菌属，乳球菌属和链球菌属，以及双歧杆菌中的一种或多种。

85. 发明申请

WO2009030636A1 METHOD AND SYSTEM FOR SYNTHESIS OF NON-PRIMARY FACIAL EXPRESSIONS 审中-公开
标题翻译：用于合成非主要表情的方法和系统
公开(公告)号：WO2009030636A1
公开(公告)日：2009-03-12
申请号：PCT/EP2008/061319
申请日：2008-08-28
申请人： NATIONAL UNIVERSITY OF IRELAND, MAYNOOTH , GHENT, John , MCDONALD, John
发明人： GHENT, John , MCDONALD, John
IPC分类号： G06K9/00 , G06T15/70
CPC分类号： G06K9/00281 , G06K9/00308
摘要： The present invention relates to a method for synthesis of a non-primary facial expression. The method comprises acquiring a facial image and calculating a shape and a texture for each of a plurality of primary facial expressions for the facial image. The method further comprises the step of generating a subject-specific model of the face including each of the primary facial expressions using the calculated shapes and textures. The method also comprises selecting an expression vector corresponding to a non-primary facial expression to be synthesised and applying the expression vector to the model to synthesise a facial image having the selected non-primary facial expression. The invention also relates to a system for synthesis of a non-primary facial expression and to a method for generating an expression look-up table.
摘要翻译：本发明涉及非主要面部表情的合成方法。该方法包括获取面部图像并计算面部图像的多个主要面部表情中的每一个的形状和纹理。该方法还包括使用所计算的形状和纹理来生成包括每个主要面部表情的面部的被摄体特定模型的步骤。该方法还包括选择与要合成的非主要面部表情相对应的表达矢量，并将表达载体应用于模型以合成具有所选择的非主要面部表情的面部图像。本发明还涉及用于合成非主要面部表情的系统和用于产生表达式查找表的方法。

86. 发明申请

WO2008114237A2 MARKER SEQUENCES FOR LABOUR 审中-公开
标题翻译：用于劳动者的标记序列
公开(公告)号：WO2008114237A2
公开(公告)日：2008-09-25
申请号：PCT/IE2008/000026
申请日：2008-03-20
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , SMITH, Terrance James , O'BRIEN, Margaret
发明人： SMITH, Terrance James , O'BRIEN, Margaret
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q2600/158
摘要： The invention relates to markers which find use in the diagnosis of labour or pre-term labour, to assays comprising such markers, to methods of identifying therapeutic agents which can prolong pregnancy, using these markers and to methods of treatment of pre-term labour, methods of prolonging gestation, or methods of suppressing labour contractility based on the markers.
摘要翻译：本发明涉及可用于诊断劳动或早产劳动的标记物，包含此类标记物的检测方法，使用这些标记物鉴定可延长怀孕的治疗剂的方法以及治疗早产儿的方法，延长妊娠的方法，或基于标记抑制劳动收缩的方法。

87. 发明申请

WO2008090534A1 METHODS AND COMPOSITIONS FOR INHIBITION OF EXCESSIVE WEIGHT GAIN, REDUCTION OF INAPPROPRIATE EATING BEHAVIOURS AND INHIBITION OF BINGE EATING FOR THE TREATMENT OF OBESITY 审中-公开
标题翻译：用于抑制体重增加的方法和组合物，减少不良的饮食行为和抑制胆汁排出以治疗肥胖
公开(公告)号：WO2008090534A1
公开(公告)日：2008-07-31
申请号：PCT/IE2008/000006
申请日：2008-01-25
申请人： BERAND LIMITED , REGAN, Claran, M. , FOLEY, Andrew, G.
发明人： REGAN, Claran, M. , FOLEY, Andrew, G.
IPC分类号： A61K31/16 , A61K31/165 , A61K31/167 , A61K31/19 , A61K31/192 , A61K31/22 , A61K31/57 , A61K31/4406 , A61K38/00 , A61P3/04
CPC分类号： A61K38/12 , A61K31/16 , A61K31/165 , A61K31/167 , A61K31/19 , A61K31/192 , A61K31/22 , A61K31/4406 , A61K31/57
摘要： The present invention relates to methods of and compositions for inhibition of excessive weight gain and reduction of inappropriate eating behaviours, and methods of and compositions for the treatment of obesity and disease characterised by abnormal weight gain. The methods and compositions are based on histone deacetylase (HDAC) inhibitors.
摘要翻译：本发明涉及用于抑制过量体重增加和减少不适当饮食行为的方法和组合物，以及以异常体重增加为特征的肥胖症和疾病的治疗方法和组合物。方法和组合物基于组蛋白脱乙酰酶（HDAC）抑制剂。

88. 发明申请

WO2008072217A2 NUCLEIC ACIDS PROBES FOR DETECTION OF YEAST AND FUNGAL SPECIES 审中-公开
标题翻译：用于检测酵母菌和真菌种的核酸探针
公开(公告)号：WO2008072217A2
公开(公告)日：2008-06-19
申请号：PCT/IE2007/000123
申请日：2007-12-14
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , BARRY, Thomas, Gerard , SMITH, Terence, James , MAHER, Majella
发明人： BARRY, Thomas, Gerard , SMITH, Terence, James , MAHER, Majella
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895
摘要： The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods.
摘要翻译：本发明使用RPS7基因的一部分或其相应的mRNA在真菌和酵母物种的诊断测定中以及用于这种测定和方法中的序列。

89. 发明申请

WO2007144864A1 SOLID-STATE FLUORESCENT ANALYSER 审中-公开
标题翻译：固态荧光分析仪
公开(公告)号：WO2007144864A1
公开(公告)日：2007-12-21
申请号：PCT/IE2007/000058
申请日：2007-06-13
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , PHELAN, Donnchadh , REDFERN, Raymond, Michael
发明人： PHELAN, Donnchadh , REDFERN, Raymond, Michael
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/6408 , G01N21/6454 , G01N2021/6484
摘要： A solid state fluorescent analyser for analysing a sample, the analyser comprising at least one pulsed light emitting diode excitation source for exciting the sample, and a single photon-counting avalanche photodiode detector for detecting fluorescence emitted from the sample, arranged so that in use with a sample to be analysed, light emitted from the pulsed light emitting diode excitation source is incident on the sample and fluorescence emitted from the excited sample is detectable by the single photon-counting avalanche photodiode detector.
摘要翻译：一种用于分析样品的固态荧光分析仪，所述分析仪包括用于激发样品的至少一个脉冲发光二极管激发源和用于检测从样品发射的荧光的单个光子计数雪崩光电二极管检测器，要分析的样品，从脉冲发光二极管激发源发射的光入射到样品上，并且从被激发的样品发射的荧光可以通过单光子计数雪崩光电二极管检测器检测。

90. 发明申请

WO2007113784A2 METHODS FOR MODULATING THE LEVELS AND EFFECTS OF THYROTROPIN-RELEASING HORMONE (TRH) AND TRH-RELATED PETIDES 审中-公开
标题翻译：调节THYROTROPIN-RELEASING HORMONE（TRH）和TRH相关PEI的水平和作用的方法
公开(公告)号：WO2007113784A2
公开(公告)日：2007-10-11
申请号：PCT/IE2007/000043
申请日：2007-03-30
申请人： THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN , KELLY, Julie , FARRAR, Jane, Gwyneth , TIVNAN, Amanda
发明人： KELLY, Julie , FARRAR, Jane, Gwyneth , TIVNAN, Amanda
IPC分类号： C12N15/113
CPC分类号： A61K38/4813 , C12N15/1137 , C12N2310/14 , C12Y304/19006
摘要： The invention provides novel methods for modulating the levels and effects of TRH and/or TRH-like peptides. These include agents for suppressing TRH-DE expression in cells, in tissues and/or in animals, such as RNAi and ribozymes. The invention has multiple applications inter alia in the generation of novel therapies for disorders related to disturbances in TRH, TRH-related peptides and TRH-DE; to modulate physiological processes; as a tool(s) for probing biological processes and mechanisms and/or as a means of generating transgenic animals.
摘要翻译：本发明提供调节TRH和/或TRH样肽的水平和作用的新方法。这些包括用于抑制细胞，组织和/或动物如RNAi和核酶中TRH-DE表达的药剂。本发明尤其涉及产生与TRH，TRH相关肽和TRH-DE紊乱有关的紊乱的新疗法; 调理生理过程; 作为探测生物过程和机制的手段和/或作为产生转基因动物的手段。

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