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71. 发明申请

US20040186555A1 Split-bridge stent design 有权
标题翻译：分体支架设计
公开(公告)号：US20040186555A1
公开(公告)日：2004-09-23
申请号：US10392936
申请日：2003-03-20
发明人： Craig Bonsignore , David J. Wilson
IPC分类号： A61F002/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91558 , A61F2230/005 , A61F2230/0054
摘要： A stent or other intraluminal medical device may be constructed utilizing a series of split-bridges interposed between a series of fixed bridges to reduce the likelihood of deformation during stent loading and stent deployment without sacrificing overall stent flexibility. The stent comprises a plurality of hoops interconnected by a plurality of fixed bridges. The stent also comprises a plurality of split-bridges, which only make contact when the stent is subjected to compressive axial loading. The stent may also comprise markers formed from housings integral with the stent and marker inserts having a higher radiopacity than the stent. This design provides for more precise placement and post-procedural visualization in a vessel, by increasing the radiopacity of the stent under X-ray fluoroscopy. The housings are formed integral to the stent and the marker inserts are made from a material close in the galvanic series to the stent material and sized to substantially minimize the effect of galvanic corrosion. The housings are also shaped to minimize their impact on the overall profile of the stent.
摘要翻译：支架或其他管腔内医疗装置可以利用插入一系列固定桥之间的一系列分裂桥来构造，以减少在支架装载和支架展开期间变形的可能性，而不牺牲整体支架的灵活性。支架包括由多个固定桥互连的多个箍。支架还包括多个分离桥，当支架经受压缩轴向负载时，其仅接触。支架还可以包括由与支架成一体的壳体形成的标记物和具有比支架更高的射线不透性的标记插入物。该设计通过在X射线荧光透视下增加支架的放射不透性来提供容器中更精确的放置和后期可视化。壳体与支架一体形成，并且标记插入物由紧邻电镀系列的材料制成到支架材料上，并且尺寸被设计成基本上最小化电偶腐蚀的影响。这些外壳也被成形为使其对支架整体轮廓的影响最小化。

72. 发明申请

US20040186554A1 Endoluminal stent having mid-strut interconnecting members 有权
标题翻译：腔内支架具有中间支柱互连构件
公开(公告)号：US20040186554A1
公开(公告)日：2004-09-23
申请号：US10803392
申请日：2004-03-18
申请人： Advanced Bio Prosthetic Surfaces, Ltd.
发明人： Christopher E. Banas , David G. Rosenbaum
IPC分类号： A61F002/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036
摘要： An endoluminal stent composed of a plurality of circumferential expansion elements arrayed to form the circumference of the stent and extending along the longitudinal axis of the stent, and a plurality of interconnecting members that interconnect adjacent pairs of circumferential expansion elements, the interconnecting members joining struts of adjacent pairs of interconnecting members at approximate mid-points of the struts.
摘要翻译：由多个周向膨胀元件组成的腔内支架，其排列成形成支架的圆周并且沿着支架的纵向轴线延伸;以及多个互连构件，其互连相邻的一对周向膨胀元件，互连构件将支柱相邻的互连构件对在支柱的大致中点处。

73. 发明申请

US20040186547A1 Luer connector portion, and stent delivery system including a connector portion 失效
标题翻译：鲁尔连接器部分和包括连接器部分的支架输送系统
公开(公告)号：US20040186547A1
公开(公告)日：2004-09-23
申请号：US10481351
申请日：2004-05-11
发明人： Jurgen Dorn , Michael Vogel
IPC分类号： A61F002/06
CPC分类号： A61F2/95 , A61F2002/9517 , A61M39/1011
摘要： The present invention relates to a connector which comprises the male portion of a Luer connector, wherein the male portion is extended axially into a pressure pad having a pressure surface.
摘要翻译：本发明涉及一种连接器，它包括一个Luer连接器的凸形部分，其中凸形部分轴向延伸到具有压力表面的压力垫中。

74. 发明申请

US20040182511A1 Pressure lamination method for forming composite ePTFE/textile and ePTFE/stent/textile prostheses 有权
标题翻译：用于形成复合ePTFE /纺织品和ePTFE /支架/纺织假体的压力层压方法
公开(公告)号：US20040182511A1
公开(公告)日：2004-09-23
申请号：US10741209
申请日：2003-12-19
申请人： SCIMED Life Systems, Inc.
发明人： Ronald Rakos , Krzysztof Sowinski
IPC分类号： A61F002/06 , B32B031/20
CPC分类号： A61L27/507 , A61F2/06 , A61F2/07 , A61F2/89 , A61F2002/072 , A61L27/16 , A61L27/48 , A61L31/048 , A61L31/129 , C08L27/18
摘要： A method of forming a composite textile and ePTFE implantable device includes the steps of (a) providing an ePTFE layer having opposed surfaces comprising a microporous structure of nodes interconnected by fibrils; (b) providing a textile layer having opposed surfaces; (c) applying a coating of an elastomeric bonding agent to one of the opposed surfaces of the ePTFE layer or the textile layer; (d) providing a hollow member having an open end and an opposed closed end defining a fluid passageway therebetween and having a wall portion with at least one hole extending therethrough, the hole being in fluid communication with the fluid passageway; (e) concentrically placing the ePTFE layer and the textile layer onto the hollow member and over the at least one hole of the hollow member to provide an interior composite layer and an exterior composite layer, thereby defining a composite assembly, wherein the interior composite layer is one of the ePTFE layer or the textile layer and the exterior composite layer is the other of the ePTFE layer or the textile layer; (f) placing the hollow member with the composite assembly within a pressure chamber; (g) applying a pressure differential so that the pressure within the chamber is greater than a pressure within the fluid passageway of the hollow member; and (h) applying heat to the bonding agent to adhesively bond the textile layer and the ePTFE layer to provide a laminated composite assembly.
摘要翻译：形成复合纺织品和ePTFE可植入装置的方法包括以下步骤：（a）提供具有相对表面的ePTFE层，所述相对表面包括通过原纤维互连的节点的微孔结构; （b）提供具有相对表面的织物层; （c）将弹性体粘合剂的涂层施加到ePTFE层或织物层的相对表面之一; （d）提供具有开口端和相对的封闭端的空心构件，所述中空构件在其间限定一个流体通路，并且具有壁部分和至少一个贯穿其中的孔，所述孔与流体通道流体连通; （e）将ePTFE层和织物层同心放置在中空构件上并且在中空构件的至少一个孔上方，以提供内部复合层和外部复合层，从而限定复合组件，其中内部复合层是ePTFE层或纺织层之一，外部复合层是ePTFE层或织物层中的另一层; （f）将具有复合组件的中空构件放置在压力室内; （g）施加压力差使得腔室内的压力大于中空构件的流体通道内的压力; 和（h）向所述粘合剂施加热量以粘合所述织物层和所述ePTFE层以提供层压复合组件。

75. 发明申请

US20040181272A1 Stent positioning system and method 有权
标题翻译：支架定位系统及方法
公开(公告)号：US20040181272A1
公开(公告)日：2004-09-16
申请号：US10812250
申请日：2004-03-29
发明人： Jeffrey W. Chambers
IPC分类号： A61F002/06
CPC分类号： A61F2/958 , A61F2002/821
摘要： A stent combined with a positioning apparatus to effectively place the stent at a precise deployment site within a narrowed vascular region such as an artery. The stent is maneuvered through the vessel and is guided by a guiding catheter up the vessel to where the narrowing is located. Upon exiting the guiding catheter and approaching the deployment site within the coronary artery, a deployment site locator expands to contact the vascular structure and, thereby, effectively position the stent at the deployment site within the narrowed vessel. This system apparatus and method is particularly useful for stent placement at an ostium (origin) of a vessel.
摘要翻译：支架与定位装置组合以有效地将支架置于狭窄的血管区域（例如动脉）内的精确部署位置。支架通过血管进行操纵，并通过引导导管向上导引到狭窄位置的位置。在离开引导导管并且接近冠状动脉内的展开部位时，展开部位定位器膨胀以接触血管结构，从而有效地将支架定位在变窄的血管内的展开部位。该系统装置和方法对于在容器的口（起点）处的支架放置是特别有用的。

76. 发明申请

US20040181237A1 Medical device for manipulation of a medical implant 有权
标题翻译：用于医疗植入物的操作的医疗装置
公开(公告)号：US20040181237A1
公开(公告)日：2004-09-16
申请号：US10386828
申请日：2003-03-12
发明人： Sean Forde , Carol A. Ryan
IPC分类号： A61F011/00 , A61F002/06
CPC分类号： A61F2/95 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00601 , A61B2017/00623 , A61F2/013 , A61F2002/011 , A61F2002/9528 , A61F2230/0006
摘要： This invention relates to medical devices for manipulating medical implants such as, for example, stents, distal protection filters, and septal occluders in a patient's body, and the methods of use thereof. Generally, a medical device of the invention includes a sleeve and an expandable component joined to the sleeve which transitions between a collapsed configuration and a deployed configuration for capturing a medical implant in a patient's body.
摘要翻译：本发明涉及用于操纵医疗植入物的医疗装置及其使用方法，例如支架，远端保护过滤器和患者体内的隔膜闭塞器。通常，本发明的医疗装置包括套筒和连接到套筒的可扩张部件，其在收缩构型和展开构型之间转变，用于捕获患者体内的医疗植入物。

77. 发明申请

US20040181235A1 Medical stent and related methods 有权
标题翻译：医疗支架及相关方法
公开(公告)号：US20040181235A1
公开(公告)日：2004-09-16
申请号：US10385209
申请日：2003-03-10
发明人： Kenneth J. Daignault , Alfred P. Intoccia
IPC分类号： A61F002/06 , A61F011/00
CPC分类号： A61M27/008 , A61M25/04 , A61M2210/1089
摘要： A stent includes a conduit defining a lumen; a first malecot adjacent the conduit, where the first malecot includes at least two members having at least one slit therebetween and where the at least one slit is in fluid communication with the lumen; and a second malecot including an annular structure surrounding and protruding from the conduit. A method for placing a stent includes inserting into a patient a stent and a stylet disposed within the stent, where the stylet includes an expandable member, expanding the expandable member, seating the stent, and removing the expandable member.
摘要翻译：支架包括限定内腔的导管; 与所述导管相邻的第一麦芽包，其中所述第一麦芽包括至少两个在其间具有至少一个狭缝的构件，并且所述至少一个狭缝与所述内腔流体连通; 以及包括围绕并从导管突出的环形结构的第二麦汁。用于放置支架的方法包括向支架和插管内插入设置在支架内的探针，其中探针包括可扩张构件，使可扩张构件膨胀，固定支架，以及移除可扩张构件。

78. 发明申请

US20040172125A1 Flexible stent 有权
公开(公告)号：US20040172125A1
公开(公告)日：2004-09-02
申请号：US10793570
申请日：2004-03-04
发明人： Robert Burgermeister
IPC分类号： A61F002/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2230/0054
摘要： A preferred embodiment of a stent provides a folded strut section that provides both structural rigidity and reduction in foreshortening of the stent mechanism. A flexible section provides flexibility for delivery of the stent mechanism. In a second embodiment, flexible section columns are angled with respect to each other, and to the longitudinal axis of the stent. These relatively flexible sections are oppositely phased in order to negate any torsion along their length. In yet another embodiment, the flexible connector can take on an undulating shape (like an nullNnull), but such that the longitudinal axis of the connector is not parallel with the longitudinal axis of the stent. Finally, a new method is disclosed for making stents. The method consists of performing a standard photochemical machining process of cutting, cleaning and coating the tube with a photoresist. However, unlike former methods, the photoresist image is developed on the surface of the cylindrical metallic tube, which results in a controlled variable etching rate at selected sites on the cylindrical metallic tube during the etching process. Further embodiments provide living hinge connectors and connections along the length of the radial strut member.

79. 发明申请

US20040167619A1 Prosthesis adapted for placement under external imaging 有权
标题翻译：假体适应放置在外部成像
公开(公告)号：US20040167619A1
公开(公告)日：2004-08-26
申请号：US10787307
申请日：2004-02-26
申请人： Cook Incorporated
发明人： Brian C. Case , Jacob A. Flagle , Michael L. Garrison , Andrew K. Hoffa , Ray Leonard II
IPC分类号： A61F002/06
CPC分类号： A61F2/2475 , A61B90/39 , A61F2/2418 , A61F2230/0026 , A61F2230/0095 , A61F2250/0098
摘要： A expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment, the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel. In another embodiment, the imageable structure is configured to permit an aperture located about a stent graft to be oriented with a anatomical feature of the vessel, such as a branch vessel opening. The invention includes a method for using imageable structure to confirm that the orientation of the prosthesis within a delivery apparatus is consistent the desired delivery approach to be used.
摘要翻译：一种具有可成像结构的可扩张假体，其包括可由外部（例如，射线照相或超声）成像系统在视觉上区分的一个或多个元件，所述结构围绕与假体的结构特征对应的第一轴定位，所述第一轴构造成执行特定于该轴的特定功能。可成像结构构造成在放置在植入部位期间有助于假体的旋转取向。在一个实施例中，假体包括静脉瓣，其包括可成像元件或结构，例如一对不透射线的标记，其限定瓣膜结构的孔，使得孔可以在成像下具有特定解剖特征，例如以将孔与容器的长轴对准。在另一个实施例中，可成像结构被配置为允许围绕支架移植物定位的孔与容器的解剖特征（例如分支血管开口）定向。本发明包括一种使用可成像结构来确认假体在输送装置内的取向与所要使用的输送方法一致的方法。

80. 发明申请

US20040167618A1 Graft deployment system 有权
标题翻译：移植部署系统
公开(公告)号：US20040167618A1
公开(公告)日：2004-08-26
申请号：US10722367
申请日：2003-11-25
发明人： Samuel M. Shaolian , Gilbert Madrid , To Van Pham , Trinh Van Pham
IPC分类号： A61F002/06
CPC分类号： A61F2/966 , A61F2/07 , A61F2/90 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2220/0058 , A61F2220/0075
摘要： A graft deployment system, comprises an elongate, flexible catheter body, having a proximal end and a distal end and comprising an outer sheath and an inner core that is axially moveable with respect to the outer sheath. A main vessel graft restraint comprising a first peelable cover for restrains a main vessel portion of a graft. In a bifurcated graft, a first branch vessel graft restraint restrains a first branch vessel portion of the graft. A second branch vessel graft restraint restrains a second branch vessel portion of the graft. The first peelable cover is coupled to a main branch release element and wherein each of the main vessel graft restraint, first branch vessel graft restraint, and the second branch vessel graft restraint are positioned within the catheter body in a graft loaded condition.
摘要翻译：移植物部署系统包括细长的柔性导管主体，其具有近端和远端并且包括外护套和可相对于外护套轴向移动的内芯。一种主血管移植物约束装置，包括用于限制移植物的主血管部分的第一可剥离盖。在分叉移植物中，第一分支血管移植物约束限制移植物的第一分支血管部分。第二分支血管移植物约束限制移植物的第二分支血管部分。第一可剥离盖联接到主分支释放元件，并且其中主血管移植物约束装置，第一分支血管移植物约束装置和第二分支血管移植物约束装置中的每一个以移植物装载状态定位在导管主体内。

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