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71. 发明申请

US20110288574A1 MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES 有权
标题翻译：医疗器械插入器和插入和使用医疗器械的过程
公开(公告)号：US20110288574A1
公开(公告)日：2011-11-24
申请号：US13071487
申请日：2011-03-24
申请人： Samuel Mason Curry , Manuel Luis Donnay , Tuan Nguyen , Louis G Pace , Peter G Robinson , Philip Yee
发明人： Samuel Mason Curry , Manuel Luis Donnay , Tuan Nguyen , Louis G Pace , Peter G Robinson , Philip Yee
IPC分类号： A61B17/34
CPC分类号： A61B5/150022 , A61B5/0002 , A61B5/01 , A61B5/1411 , A61B5/14503 , A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/15016 , A61B5/150259 , A61B5/150282 , A61B5/150396 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/150732 , A61B5/15087 , A61B5/15107 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/6865 , A61B17/34 , A61M5/158 , A61M2005/1585
摘要： An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.
摘要翻译：提供了用于将医疗装置插入被检体的皮肤的装置以及插入医疗装置的方法。

72. 发明申请

US20100268043A1 Device and Method for Preventing Diabetic Complications 审中-公开
标题翻译：用于预防糖尿病并发症的装置和方法
公开(公告)号：US20100268043A1
公开(公告)日：2010-10-21
申请号：US12741715
申请日：2008-11-04
申请人： Ofer Yodfat , Gali Shapira
发明人： Ofer Yodfat , Gali Shapira
IPC分类号： A61M37/00 , A61B5/1473
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/145 , A61B5/14546 , A61B5/14865 , A61B5/6849 , A61B5/6865 , A61M5/14248 , A61M5/1723 , A61M2005/14252 , A61M2005/14268 , A61M2005/1726 , A61M2230/201
摘要： Methods, systems and devices for preventing diabetic complications are provided. In some embodiments, methods, systems and devices can be implemented using at least one subcutaneously insertable element, the element having a proximal portion and a distal portion, the proximal portion coupled to the housing, the distal portion configured for subcutaneous placement within a human body; a plurality of electrodes coupled to the distal portion of the at least one subcutaneously insertable element; and, a processor adapted to correlate a signal received from the plurality of electrodes to a concentration of ketone in the human body.
摘要翻译：提供了用于预防糖尿病并发症的方法，系统和装置。在一些实施例中，方法，系统和装置可以使用至少一个皮下可插入元件实现，所述元件具有近端部分和远端部分，所述近端部分联接到所述外壳，所述远端部分被配置为皮下放置在人体内 ; 耦合到所述至少一个皮下可插入元件的远端部分的多个电极; 以及适于将从多个电极接收的信号与人体中的酮浓度相关联的处理器。

73. 发明申请

US20100161018A1 Transcranial Securing Device for Deep Brain Stimulation Leads 有权
标题翻译：用于深脑刺激潜能的经颅固定装置
公开(公告)号：US20100161018A1
公开(公告)日：2010-06-24
申请号：US12603062
申请日：2009-10-21
申请人： Fabien Sauter-Starace , Alim-Louis Benabid , Raymond Charles
发明人： Fabien Sauter-Starace , Alim-Louis Benabid , Raymond Charles
IPC分类号： A61N1/05
CPC分类号： A61N1/0534 , A61B5/4082 , A61B5/6864 , A61B5/6865 , A61B5/6882 , A61B2017/3445 , A61B2017/347 , A61B2090/103 , A61N1/0539
摘要： A transcranial securing device for deep brain stimulation leads comprising: a principal part for securing inside an opening formed in the cranium of a patient; and at least one first securing part housed inside said principal part; said or each securing part comprises at least one axial bore adapted to allow the passage of one or more deep brain stimulation leads; said or at least one securing part is arranged so as to be capable of passing from a first position in which the lead or leads can slide axially in the respective bores, to a second position in which it grips the lead or leads in the respective bore or bores, preventing said sliding.
摘要翻译：一种用于深脑刺激引线的经颅固定装置，包括：用于固定在形成于患者颅骨中的开口内的主要部分; 以及容纳在所述主要部分内的至少一个第一固定部分; 所述或每个固定部分包括适于允许一个或多个深部脑刺激引线通过的至少一个轴向孔; 所述或至少一个固定部分布置成能够从其中所述引线或引线在相应的孔中轴向滑动的第一位置通过到第二位置，在所述第二位置，所述第一位置将所述引线或引线夹在相应的孔中或孔，防止所述滑动。

74. 发明申请

US20090085768A1 GLUCOSE SENSOR TRANSCEIVER 审中-公开
标题翻译：葡萄糖传感器收发器
公开(公告)号：US20090085768A1
公开(公告)日：2009-04-02
申请号：US12056651
申请日：2008-03-27
申请人： Himanshu Patel , Wayne A. Morgan , Edward Chernoff , John J. Mastrototaro
发明人： Himanshu Patel , Wayne A. Morgan , Edward Chernoff , John J. Mastrototaro
IPC分类号： G08C19/06
CPC分类号： H04Q9/02 , A61B5/002 , A61B5/0022 , A61B5/14532 , A61B5/14865 , A61B5/6865 , G08C2201/40 , G08C2201/51 , G16H40/67 , H04Q2209/40 , H04Q2209/84 , H04Q2209/883
摘要： The present invention relates to a telemetered characteristic sensor transceiver for exchanging data with at least one remote device. The transceiver includes a housing detachably coupled to a sensor located on a body of a user, the sensor producing a signal indicative of a user characteristic. A processor is formed within the housing and in communication with the sensor for processing the signal produced by the sensor. A transmitter is coupled to the processor for transmitting data to at least one remote device while a receiver is coupled to the processor for receiving data from the at least one remote device. A memory is coupled to the processor for storing data, wherein the processor performs calculations using at least one of the signal produced by the sensor, the data received from the at least one remote device and the data stored in the memory, and performs at least one of storing the calculations in the memory and transmitting the calculations to the at least one remote device through the transmitter.
摘要翻译：本发明涉及一种用于与至少一个远程设备交换数据的遥测特征传感器收发器。收发器包括可拆卸地联接到位于用户身体上的传感器的壳体，该传感器产生指示用户特征的信号。处理器形成在壳体内并与传感器通信，用于处理由传感器产生的信号。发射器耦合到处理器，用于在至少一个远程设备的同时将数据传输到至少一个远程设备，而接收机耦合到处理器，用于从至少一个远程设备接收数据。存储器耦合到处理器用于存储数据，其中处理器使用由传感器产生的信号，从至少一个远程设备接收的数据和存储在存储器中的数据中的至少一个来执行计算，并且执行至少一种将计算存储在存储器中并通过发送器将计算发送到至少一个远程设备。

75. 发明授权

US06438397B1 Method and apparatus for analyte detection using intradermally implanted skin port 失效
标题翻译：使用皮内植入皮肤端口进行分析物检测的方法和装置
公开(公告)号：US06438397B1
公开(公告)日：2002-08-20
申请号：US09429191
申请日：1999-10-28
申请人： Gerald G. Bosquet , Gerald L. Cote , Ashok Gowda , Roger McNichols , Sohi Rastegar
发明人： Gerald G. Bosquet , Gerald L. Cote , Ashok Gowda , Roger McNichols , Sohi Rastegar
IPC分类号： A61B500
CPC分类号： A61B5/6865 , A61B5/14532 , A61B5/14552 , A61B5/1459
摘要： A transcutaneous, implantable skin port sensor includes an access component and a sensor component, both of which can be made from inexpensive biocompatible materials. The access component provides a biological seal that forms around the skin port sensor. The sensor component facilitates non-invasive optically based measurement of analytes by providing a window to the body which avoids changes in the optical signal due to variations in skin optics, optical pathlength, ambient temperature and probe pressure. Tissue ingrowth or interstitial fluid in a through portion downstream of the optical window serves as the sample for the non-invasive, optically based measurement.
摘要翻译：经皮的植入式皮肤端口传感器包括通路部件和传感器部件，两者均可由廉价的生物相容性材料制成。进入部件提供围绕皮肤端口传感器形成的生物密封。传感器组件通过向身体提供窗口来促进分析物的非侵入性光学测量，从而避免由于皮肤光学，光程长度，环境温度和探针压力的变化而导致的光信号变化。在光学窗口下游的通过部分中的组织向内生长或间质液体用作非侵入式光学测量的样品。

76. 发明授权

US5651767A Replaceable catheter system for physiological sensors, stimulating electrodes and/or implantable fluid delivery systems 失效
标题翻译：用于生理传感器，刺激电极和/或可植入流体输送系统的可更换的导管系统
公开(公告)号：US5651767A
公开(公告)日：1997-07-29
申请号：US587881
申请日：1996-01-11
申请人： Joseph H. Schulman , Alfred E. Mann , Charles L. Byers , Jack W. Love
发明人： Joseph H. Schulman , Alfred E. Mann , Charles L. Byers , Jack W. Love
IPC分类号： A61N1/05 , A61M5/00
CPC分类号： A61N1/05 , A61B5/6865
摘要： A replaceable catheter system provides a way to replace an implantable sensor, electrode system, and/or fluid delivery/receiving system. The replaceable catheter system includes an implantable shunt, such as an arteriovenous shunt, attached to an implantable introducer. The introducer and implantable shunt are adapted for surgical implantation within a patient such that it extends from immediately below the patient's skin to the implantable shunt site. The replaceable catheter system further includes a replaceable catheter that is adapted to be contained within the introducer and properly aligned such that an implantable sensor, electrode system, and/or fluid delivery system that is carried by the replaceable catheter is placed in operative association with the implantable shunt and exposed to any fluids passing through the implantable shunt.
摘要翻译：可替换的导管系统提供了替代可植入传感器，电极系统和/或流体递送/接收系统的方法。可替换的导管系统包括可植入的分流器，例如静脉分流器，其附接到可植入导引器。导引器和可植入分流装置适于在患者体内进行手术植入，使得其从患者皮肤的正下方延伸到可植入分流部位。可替换的导管系统还包括可更换的导管，其适于容纳在导引器内并且适当对准，使得由可更换导管携带的可植入传感器，电极系统和/或流体输送系统与可植入分流器并暴露于通过可植入分流器的任何流体。

77. 发明授权

US5437278A Medical diagnosis system and method 失效
标题翻译：医疗诊断系统及方法
公开(公告)号：US5437278A
公开(公告)日：1995-08-01
申请号：US819120
申请日：1992-01-10
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61B5/00 , A61B5/107 , A61B7/04 , A61B8/00
CPC分类号： A61B5/6876 , A61B5/0022 , A61B5/4839 , A61B5/6865 , A61B5/6884 , A61B7/04 , A61B8/00 , A61B8/42 , A61B5/0031 , A61B5/1075 , A61B8/4236
摘要： A medical diagnostic system comprises a monitoring device juxtaposable to a patient for collecting individualized medical data about the patient's condition, and a digitizer operatively connected to the monitoring device for digitizing the data. A computer is operatively connected to the digitizer and a memory which stores medical data for a multiplicity of previously diagnosed medical conditions. The computer is operated to compare digitized data about the patient's condition with the data stored in the memory and for deriving a diagnosis as to the patient's condition. The computer is connected to an ooutput device, e.g., a printer, for communicating the derived diagnosis to a user.
摘要翻译：医疗诊断系统包括与患者并置的监测装置，用于收集关于患者状况的个体化医疗数据，以及可操作地连接到监视装置的数字化仪，用于数字化数据。计算机可操作地连接到数字转换器和存储多个先前诊断的医疗状况的医学数据的存储器。计算机被操作以将关于患者状况的数字化数据与存储在存储器中的数据进行比较，并用于导出关于患者状况的诊断。计算机连接到输出设备，例如打印机，用于将导出的诊断传达给用户。

78. 发明授权

US4685463A Device for continuous in vivo measurement of blood glucose concentrations 失效
标题翻译：用于连续体内测量血糖浓度的装置
公开(公告)号：US4685463A
公开(公告)日：1987-08-11
申请号：US847479
申请日：1986-04-03
申请人： R. Bruce Williams
发明人： R. Bruce Williams
IPC分类号： A61B5/00 , C12Q1/54
CPC分类号： A61B5/14865 , A61B5/14528 , A61B5/686 , A61B5/6865 , C12Q1/54
摘要： A device is disclosed for continuous in vivo measurement of blood glucose concentrations in arterial blood. A quantity of glucose oxidase enzyme is confined within at least one elongate double-lumened tube by means of a semi-permeable membrane tubule permeable to permit diffusion of glucose from blood passing through an inner lumen of the tube into an outer lumen in which the enzyme is confined. The enzyme catalyzes the oxidation of glucose to produce heat. The tube is insulated so that the heat produced by the glucose oxidation is transferred to the blood flowing through the inner lumen. Either micro-thermocouples or solid state temperature sensors are positioned to measure the increase in temperature of the blood to produce a signal that is a function of the glucose concentration in the blood.
摘要翻译：公开了用于连续体内测量动脉血中血糖浓度的装置。一定数量的葡萄糖氧化酶被限制在至少一个细长的双重管腔中，该管可透过的半透膜微管允许葡萄糖从血液中通过管的内腔扩散到外腔中，被限制酶催化葡萄糖的氧化产生热量。管被绝缘，使得由葡萄糖氧化产生的热量被传递到流过内腔的血液。定位微热电偶或固态温度传感器以测量血液的温度升高以产生作为血液中葡萄糖浓度的函数的信号。

79. 发明公开

US20240130684A1 IMPLANTABLE APPARATUS FOR SENSING BIOLOGIC SIGNALS 审中-公开
公开(公告)号：US20240130684A1
公开(公告)日：2024-04-25
申请号：US18399914
申请日：2023-12-29
申请人： EFFERENT LABS, INC.
发明人： Marek Kowarz , Spencer Rosero
IPC分类号： A61B5/00 , A61B10/02 , G01N21/64
CPC分类号： A61B5/6865 , A61B10/02 , G01N21/64 , A61B2560/0219 , A61B2562/0233 , G01N2201/062 , G01N2201/0693
摘要： An implantable apparatus for physiological measurement in a host organism has an implantable sample chamber having a measurement port and live cells that are treated to fluoresce in response to light having an excitation wavelength. An optical sensor housing implanted within the host organism has a window to convey excitation light output and receive fluorescent light; a coupling that couples the measurement port of the sample chamber to the window; an optical chamber partitioned into an excitation sub-chamber and a detection sub-chamber, wherein both sub-chambers are in optical communication with the window; an excitation source energizable to direct excitation light through the excitation sub-chamber and to the window; and a detector in the path of fluorescent light received from the live cells. A signal processing apparatus is energizable to acquire and process a detector signal and to transmit a processed signal that is indicative of fluorescent light energy.

80. 发明授权

US11872086B2 Surgical image-guided navigation devices and related systems 有权
公开(公告)号：US11872086B2
公开(公告)日：2024-01-16
申请号：US16675690
申请日：2019-11-06
申请人： ClearPoint Neuro, Inc.
发明人： Parag V. Karmarkar , Kimble Jenkins
IPC分类号： A61B5/05 , A61B90/11 , A61B34/20 , A61B5/00 , A61N1/05 , G01R33/28 , G01R33/34 , A61B5/369 , A61B5/055 , A61B34/10 , A61B90/14 , A61M39/08 , A61N1/08 , A61N1/372 , A61B90/00 , A61B17/00 , A61N1/37 , G01R33/48
CPC分类号： A61B90/11 , A61B5/055 , A61B5/369 , A61B5/6847 , A61B5/6864 , A61B5/6865 , A61B5/7435 , A61B34/10 , A61B34/20 , A61B90/14 , A61M39/08 , A61N1/0529 , A61N1/0534 , A61N1/0539 , A61N1/08 , G01R33/285 , G01R33/286 , G01R33/287 , G01R33/34084 , A61B2017/00039 , A61B2034/107 , A61B2034/2051 , A61B2090/374 , A61B2090/3954 , A61N1/086 , A61N1/372 , A61N1/3718 , G01R33/288 , G01R33/4808
摘要： MRI compatible localization and/or guidance systems for facilitating placement of an interventional therapy and/or device in vivo include: (a) a mount adapted for fixation to a patient; (b) a targeting cannula with a lumen configured to attach to the mount so as to be able to controllably translate in at least three dimensions; and (c) an elongate probe configured to snugly slidably advance and retract in the targeting cannula lumen, the elongate probe comprising at least one of a stimulation or recording electrode. In operation, the targeting cannula can be aligned with a first trajectory and positionally adjusted to provide a desired internal access path to a target location with a corresponding trajectory for the elongate probe. Automated systems for determining an MR scan plane associated with a trajectory and for determining mount adjustments are also described.

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