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71. 发明申请

US20080063228A1 Accoustically Transparent Occlusion Reduction System and Method 有权
标题翻译：透声闭塞减少系统及方法
公开(公告)号：US20080063228A1
公开(公告)日：2008-03-13
申请号：US11576175
申请日：2005-09-30
申请人： Jorge Mejia , Harvey Dillon , Michael Fisher
发明人： Jorge Mejia , Harvey Dillon , Michael Fisher
IPC分类号： H04R25/00
CPC分类号： H04R25/502 , H04R25/407 , H04R25/505 , H04R2460/05
摘要： A system and method that reduces the perceptual effect resulting from ear occlusion is disclosed. It comprises of an electro-acoustic feedback network that produces phase cancelling sounds in the ear, where a receiver and a microphone are located. A novel control mechanism is disclosed that controls the response of the feedback network to minimise distortion in the ear while maintaining a desired frequency response for external signals. Devices producing the external signal include hearing aids, personal sound devices, in ear monitors, communications headsets and hearing protectors. The integration of the present invention with these devices improves the user's perception of their own voice.
摘要翻译：公开了一种降低耳塞闭塞感知效果的系统和方法。它包括电声反馈网络，其在耳朵中产生相位消除声音，其中接收器和麦克风位于其中。公开了一种新颖的控制机制，其控制反馈网络的响应以最小化耳朵中的失真，同时保持对外部信号的期望的频率响应。产生外部信号的装置包括助听器，个人声音装置，耳朵监视器，通信耳机和听力保护器。本发明与这些装置的集成改善了用户对自己的声音的感知。

72. 发明申请

US20070249211A1 Method and apparatus for achieving rigid attachments for computer components 失效
标题翻译：用于实现计算机部件的刚性附件的方法和装置
公开(公告)号：US20070249211A1
公开(公告)日：2007-10-25
申请号：US11407020
申请日：2006-04-19
申请人： Joseph Corrado , Michael Fisher , Gerald Monaco , Budy Notohardjono
发明人： Joseph Corrado , Michael Fisher , Gerald Monaco , Budy Notohardjono
IPC分类号： H01R13/627
CPC分类号： G06F1/181
摘要： A method and apparatus used for actuation is provided. In one embodiment, the apparatus comprises an actuation body having a gradually tapered wider end received at one end by an expandable member and at an opposing end by a drive shell. The actuation body being movable from a first position to a second position by means of the drive shell such that this movement causes a looser or tighter fit at the wider end with respect to the expandable member.
摘要翻译：提供了用于致动的方法和装置。在一个实施例中，该装置包括致动体，该致动体具有逐渐变细的较宽端部，其一端通过可扩张构件接收，并且在相对端处由驱动壳体接收。致动体可借助于驱动壳体从第一位置移动到第二位置，使得该移动使得相对于可扩张构件在较宽端部处更松散或更紧密地配合。

73. 发明申请

US20070083209A1 Transverse acting surgical saw blade 有权
标题翻译：横向作用手术锯片
公开(公告)号：US20070083209A1
公开(公告)日：2007-04-12
申请号：US11234754
申请日：2005-09-23
申请人： Jon Schenberger , Michael Fisher
发明人： Jon Schenberger , Michael Fisher
IPC分类号： A61B17/00
CPC分类号： A61B17/142 , A61B17/14 , A61B2017/00734
摘要： Various embodiments provide surgical cutting devices and systems for orthopedic and other procedures. Specific embodiments provide saw devices for accessing and cutting subjacent bone and other tissue while minimizing injury to surrounding tissue. One embodiment provides a transverse acting saw blade for performing surgical cuts to bone tissue with minimal injury to surrounding tissue. The blade comprises an elongated member having a first portion and a second portion and a longitudinal and lateral axis. The first portion is configured to engage a drive source to produce longitudinal movement of the first portion that is atraumatic to surrounding tissue. The second portion includes a cutting surface. The longitudinal movement of the first portion is converted to a lateral movement of the second portion that is sufficient to cut engaged bone tissue with the cutting surface. The movement of the second portion is substantially transverse to the movement of the first portion.
摘要翻译：各种实施例提供用于矫形和其他手术的外科切割装置和系统。具体实施例提供用于进入和切割下面的骨骼和其他组织的锯装置，同时使对周围组织的损伤最小化。一个实施例提供了一种横向作用锯片，用于对周围组织的损伤以最小的损伤进行骨组织的手术切割。刀片包括具有第一部分和第二部分以及纵向和横向轴线的细长部件。第一部分被配置为接合驱动源以产生对周围组织无伤害的第一部分的纵向运动。第二部分包括切割表面。第一部分的纵向运动被转换为第二部分的横向移动，其足以切割与切割表面接合的骨组织。第二部分的运动基本上横向于第一部分的运动。

74. 发明申请

US20060270679A1 Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes 审中-公开
公开(公告)号：US20060270679A1
公开(公告)日：2006-11-30
申请号：US11500252
申请日：2006-08-07
申请人： Scott Edmondson , Michael Fisher , Dooseop Kim , Malcolm Maccoss , Emma Parmee , Ann Weber , Jinyou Xu
发明人： Scott Edmondson , Michael Fisher , Dooseop Kim , Malcolm Maccoss , Emma Parmee , Ann Weber , Jinyou Xu
IPC分类号： A61K31/498 , C07D487/04
CPC分类号： A61K31/4985 , A61K31/498 , A61K38/28 , A61K45/06 , C07D487/04 , Y10S514/866 , A61K2300/00
摘要： The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

75. 发明申请

US20060087813A1 System for airflow management in electronic enclosures 有权
标题翻译：电子机柜气流管理系统
公开(公告)号：US20060087813A1
公开(公告)日：2006-04-27
申请号：US10972868
申请日：2004-10-25
申请人： Wiren Becker , Joseph Corrado , Ethan Cruz , Michael Fisher , Gary Goth
发明人： Wiren Becker , Joseph Corrado , Ethan Cruz , Michael Fisher , Gary Goth
IPC分类号： H05K1/00
CPC分类号： H05K7/20563 , G06F1/183 , G06F1/20
摘要： A system for airflow management in an electronic enclosure includes a backplane assembly having at least one backplane connector, at least one daughter card, and components disposed on the daughter card oriented to facilitate front-to-back airflow, wherein inlet cooling air impinges on the backplane assembly and splits into at least two flow portions flowing in different directions along a surface defining the backplane assembly
摘要翻译：一种用于电子外壳中的气流管理的系统包括背板组件，该背板组件具有至少一个背板连接器，至少一个子卡，以及设置在子卡上的部件，其定向成便于前后气流，其中入口冷却空气冲击底板组件，并分成沿着限定背板组件的表面沿不同方向流动的至少两个流动部分

76. 发明申请

US20050177170A1 Dynamic knee balancer with pressure sensing 有权
标题翻译：带压力感应的动态膝盖平衡器
公开(公告)号：US20050177170A1
公开(公告)日：2005-08-11
申请号：US10973936
申请日：2004-10-25
申请人： Michael Fisher , Anthony Hedley , Michael Howard , Kevin Cordes , Toshinobu Katsuya
发明人： Michael Fisher , Anthony Hedley , Michael Howard , Kevin Cordes , Toshinobu Katsuya
IPC分类号： A61B17/00 , A61B17/02 , A61B17/15 , A61B17/58 , A61B17/90 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/30 , A61F2/38 , A61F2/46
CPC分类号： A61B17/02 , A61B17/025 , A61B17/155 , A61B2017/0268 , A61B2090/064 , A61F2/38 , A61F2/4657 , A61F2/4684 , A61F2002/30092 , A61F2002/30428 , A61F2002/30507 , A61F2002/30538 , A61F2002/30553 , A61F2002/30566 , A61F2210/0014 , A61F2220/0025 , A61F2250/0006 , A61F2250/0008 , G06F19/00
摘要： A device for performing a surgical procedure on a knee includes an adjustable femoral portion, a tibial portion and at least one sensor coupled with the femoral and/or tibial portions to sense pressure exerted by the femoral and tibial portions against one another. The femoral portion is adapted for removably coupling with a distal end of a femur to adjust tension in soft tissue adjacent the knee and has at least one positioning feature adapted to move relative to the distal end of the femur as the femoral portion is adjusted, thus helping position a femoral prosthetic on the distal end of the femur. The sensor(s) may be adapted to sense pressure at medial and lateral sides of the knee, and relative pressures may be displayed as data on a visual display. Adjustments to the femoral member may be made to balance pressure at flexion and extension of the knee.
摘要翻译：用于在膝盖上执行外科手术的装置包括可调整的股骨部分，胫骨部分和与股骨和/或胫骨部分联接的至少一个传感器，以感测由股骨和胫骨部分彼此抵抗的压力。股骨部分适于与股骨的远端可移动地联接以调节邻近膝盖的软组织中的张力，并且具有适于在调节股骨部分时相对于股骨的远端移动的至少一个定位特征，因此帮助股骨假体位于股骨远端。传感器可以适于感测膝盖的内侧和外侧的压力，并且相对压力可以作为数据显示在视觉显示器上。可以对股骨构件进行调整，以平衡膝盖弯曲和伸展时的压力。

77. 发明申请

US20050149599A1 Policy based system management 有权
标题翻译：基于策略的系统管理
公开(公告)号：US20050149599A1
公开(公告)日：2005-07-07
申请号：US10507902
申请日：2003-03-27
申请人： Sohail Rana , Paul McKee , Michael Fisher
发明人： Sohail Rana , Paul McKee , Michael Fisher
IPC分类号： G06F9/46 , H04L12/24 , G06F15/16
CPC分类号： H04L41/046 , G06F9/465 , G06Q20/203 , H04L41/0893
摘要： A computer network is managed by policies. This allows selections to be made from a range of control options and optionally to be based on locally available system information. Policy-based management is distributed across the system and is handled locally by management agents (70) allowing control of a sub-network (72). As a result a distributed policy-based management system is provided which allows additional flexibility of control.
摘要翻译：计算机网络由策略管理。这允许从一系列控制选项进行选择，并且可选地基于本地可用的系统信息。基于策略的管理被分布在整个系统中并且由允许对子网络（72）的控制的管理代理（70）在本地处理。因此，提供了一种分布式的基于策略的管理系统，允许更多的控制灵活性。

78. 发明申请

US20050126420A1 Wall breaching apparatus and method 审中-公开
标题翻译：墙体破坏装置及方法
公开(公告)号：US20050126420A1
公开(公告)日：2005-06-16
申请号：US10938199
申请日：2004-09-10
申请人： Richard Givens , Michael Fisher , Thomas Burky , Jerome Klein , Graham Alexander , Jason Paugh
发明人： Richard Givens , Michael Fisher , Thomas Burky , Jerome Klein , Graham Alexander , Jason Paugh
IPC分类号： F42B3/08 , F42D3/00 , F42B1/00
CPC分类号： F42B1/02 , F42B3/02 , F42B3/08 , F42D3/00
摘要： Wall breaching apparatus and methods utilizing shaped charges for penetration of walls of buildings and other structures for rescue, escape, or military operations.
摘要翻译：墙体破坏装置和方法利用成形装置对建筑物和其他结构的墙壁进行穿透以进行救援，逃生或军事行动。

79. 发明申请

US20050119261A1 Biaryl substituted triazoles as sodium channnel blockers 有权
标题翻译：二芳基取代三唑作为钠通道阻断剂
公开(公告)号：US20050119261A1
公开(公告)日：2005-06-02
申请号：US10799230
申请日：2004-03-12
申请人： Prasun Chakravarty , Michael Fisher , Jeffrey Fisher , Brenda Palucki , Min Park , William Parsons , Bishan Zhou , James Carey , Douglas Frantz , Michael Kress , Damian Weaver
发明人： Prasun Chakravarty , Michael Fisher , Jeffrey Fisher , Brenda Palucki , Min Park , William Parsons , Bishan Zhou , James Carey , Douglas Frantz , Michael Kress , Damian Weaver
IPC分类号： A61K31/4196 , A61P25/00 , C07D249/08 , C07D249/10 , C07D413/02 , A61K31/496 , A61K31/506 , A61K31/5377 , C07D417/02 , C07D43/02
CPC分类号： C07D249/08 , C07D249/10
摘要： Biaryl substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof, and a process for making such compounds and salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds. A method of administering local anesthesia comprises administering an effective amount of a compound of the instant invention, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier.
摘要翻译：由式I，II或III表示的二芳基取代的三唑化合物或其药学上可接受的盐，以及其制备方法。药物组合物包含单独的或与一种或多种其它治疗活性化合物组合的有效量的本发明化合物和药学上可接受的载体。治疗与钠通道活性相关或由其引起的疾病的方法，包括例如急性疼痛，慢性疼痛，内脏痛，炎性疼痛，神经性疼痛，癫痫，肠易激综合征，抑郁症，焦虑症，多发性硬化症和双相包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物组合施用。施用局部麻醉的方法包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物和药学上可接受的载体组合施用。

80. 发明授权

US5374275A Surgical suturing device and method of use 失效
标题翻译：手术缝合装置及使用方法
公开(公告)号：US5374275A
公开(公告)日：1994-12-20
申请号：US37572
申请日：1993-03-25
申请人： James G. Bradley , Michael Fisher
发明人： James G. Bradley , Michael Fisher
IPC分类号： A61B17/00 , A61B17/04 , A61M23/00
CPC分类号： A61B17/0469 , A61B17/0057 , A61B2017/047 , A61B2017/0472
摘要： A surgical device for closing an incision created by a trocar or similar surgical device is disclosed. The surgical device comprises a support member within which are disposed a first and second needle positioning means. Each of these means carries a suture needle in retrorse configuration relative to the distal end of the support member. The needles can be retracted or deployed relative to the support member in a plurality of desired positions. In operation, the needles are deployed at a desired distance from the edge of the incision. The surgeon then pulls the device out of the body of the patient, thereby capturing and pulling the needles through first the peritoneum followed by the fascia. Needle capture means are provided which retain and remove the needles after the peritoneum and fascia are sutured, leaving the loose ends of the suture thread which can then be tied off below skin level to close the incision.
摘要翻译：公开了一种用于封闭由套管针或类似手术装置产生的切口的手术装置。手术装置包括支撑构件，在支撑构件内设置有第一和第二针定位装置。这些装置中的每个装置相对于支撑构件的远端携带以反向构造的缝合针。针可以相对于支撑构件在多个期望位置中缩回或展开。在操作中，针从切口的边缘以期望的距离展开。外科医生然后将装置从患者的身体拉出，从而首先将针头收紧并拉出腹膜，然后是筋膜。提供针捕获装置，其在腹膜和筋膜缝合之后保留和移除针，留下缝合线的松散端，然后将其缝合在皮肤层下方以封闭切口。

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