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71. 发明申请

US20100023078A1 Cardiac resynchronization therapy parameter optimization 有权
标题翻译：心脏再同步治疗参数优化
公开(公告)号：US20100023078A1
公开(公告)日：2010-01-28
申请号：US11338935
申请日：2006-01-25
申请人： Yanting Dong , Yinghong Yu , Jiang Ding , Scott A. Meyer , Xuan Wei , Michael John Stucky
发明人： Yanting Dong , Yinghong Yu , Jiang Ding , Scott A. Meyer , Xuan Wei , Michael John Stucky
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/36585 , A61N1/3684
摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.
摘要翻译：系统和方法涉及使用多个CRT优化过程来确定CRT参数。每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。可以基于返回的推荐参数的组合来确定CRT参数。可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

72. 发明申请

US20100016920A1 SYSTEMS AND METHODS FOR COLLECTING PATIENT EVENT INFORMATION 有权
标题翻译：收集患者事件信息的系统和方法
公开(公告)号：US20100016920A1
公开(公告)日：2010-01-21
申请号：US12504450
申请日：2009-07-16
申请人： Stephen J. Hahn , Yanting Dong , Haresh G. Sachanandani , Kenneth P. Hoyme , James O. Gilkerson
发明人： Stephen J. Hahn , Yanting Dong , Haresh G. Sachanandani , Kenneth P. Hoyme , James O. Gilkerson
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/37258 , A61N1/3962
摘要： A method of and system for collecting patient event information from a cardiac rhythm management system (CRM system) is described, where the CRM system includes a cardiac rhythm management device (CRM device) and an external interface device. The method includes the steps of initiating a transmission session wherein the interface device communicates with the CRM device, prompting a user of the CRM system to select a reason for the transmission session, inputting the selected reason for the transmission session to the interface device, and storing the selected reason for the transmission session and timestamp information for the transmission session.
摘要翻译：描述了一种从心律管理系统（CRM系统）收集患者事件信息的方法和系统，其中CRM系统包括心律管理装置（CRM装置）和外部接口装置。该方法包括以下步骤：启动传输会话，其中接口设备与CRM设备通信，提示CRM系统的用户选择传输会话的原因，向接口设备输入传输会话的选择原因;以及存储用于传输会话的选择原因和用于传输会话的时间戳信息。

73. 发明授权

US07555340B2 Electrogram morphology-based CRT optimization 有权
标题翻译：基于电图形态的CRT优化
公开(公告)号：US07555340B2
公开(公告)日：2009-06-30
申请号：US11097460
申请日：2005-04-01
申请人： Yanting Dong , Jiang Ding , Douglas R. Daum , Scott A. Meyer , Yinghong Yu
发明人： Yanting Dong , Jiang Ding , Douglas R. Daum , Scott A. Meyer , Yinghong Yu
IPC分类号： A61N1/365
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/371
摘要： A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.
摘要翻译：一种用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟（AVD）间隔和/或心室 - 心室延迟（VVD）间隔的方法和系统。以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。

74. 发明申请

US20090043355A1 SYSTEM FOR EVALUATING PERFORMANCE OF AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于评估可植入医疗器械性能的系统
公开(公告)号：US20090043355A1
公开(公告)日：2009-02-12
申请号：US11835812
申请日：2007-08-08
申请人： Shelley M. Cazares , Haresh G. Sachanandani , Benjamin Ettori , Dan Li , Yanting Dong
发明人： Shelley M. Cazares , Haresh G. Sachanandani , Benjamin Ettori , Dan Li , Yanting Dong
IPC分类号： A61N1/02
CPC分类号： A61N1/37282 , A61B5/0031 , A61N1/3627 , A61N1/36585 , G06F19/00 , G06F19/3418 , G16H40/63
摘要： A system evaluates the performance of an implantable medical device, such as by using a remote external server and a user interface and stored historical physiological data of a population of congestive heart failure (CHF) patients. A processor is coupled to a patient data storage device to apply multiple algorithm variations against the same implantable physiological data from the patient to produce corresponding resulting CHF indicators. The user interface includes a display that is configured to display to a user information allowing comparison between the resulting CHF indicators from the multiple algorithm variations. The display also includes a population data selector to permit the user to select physiological data from a population that includes a different set of one or more patients or physiological data collected over a period of time from the patient. This permits optimization of an algorithm parameter or selection of a best performing algorithm.
摘要翻译：系统评估可植入医疗装置的性能，例如通过使用远程外部服务器和用户界面以及存储充血性心力衰竭（CHF）患者群体的历史生理数据。处理器耦合到患者数据存储装置，以对来自患者的相同的可植入生理数据应用多个算法变化，以产生相应的所得CHF指示符。用户界面包括被配置为向用户显示信息的显示器，允许根据多个算法变化比较所得到的CHF指示符。显示器还包括种群数据选择器，以允许用户从包括不同组的一个或多个患者或在患者的一段时间内收集的生理数据的群体中选择生理数据。这允许优化算法参数或选择最佳执行算法。

75. 发明申请

US20080262558A1 PATIENT CHARACTERISTIC BASED ADAPTIVE ANTI-TACHY PACING PROGRAMMING 有权
标题翻译：基于特征特征的自适应防篡改编程
公开(公告)号：US20080262558A1
公开(公告)日：2008-10-23
申请号：US11736286
申请日：2007-04-17
申请人： Yanting Dong , Quan Ni , Xuan Wei , Dan Li , Qian Zhong
发明人： Yanting Dong , Quan Ni , Xuan Wei , Dan Li , Qian Zhong
IPC分类号： A61N1/365
CPC分类号： A61N1/3621
摘要： A system including at least one implantable sensor circuit adapted to produce an electrical sensor signal related to one or more physiologic cardiovascular events of a subject, a therapy circuit configured to provide anti-tachycardia pacing (ATP) therapy, and a controller. The controller includes a tachyarrhythmia detection circuit and an efficacy circuit. The tachyarrhythmia detection circuit is configured to detect a tachyarrhythmia episode in the subject using the electrical sensor signal, and to determine whether the tachyarrhythmia episode is of a type that is treatable with ATP. The efficacy circuit is configured to estimate an efficacy of a currently configured ATP therapy for the subject, and the controller is configured to alter a delivery regimen of the currently configured ATP therapy when the estimated ATP therapy efficacy is deemed insufficient. Other systems and methods are described.
摘要翻译：一种系统，包括适于产生与受试者的一个或多个生理性心血管事件相关的电传感器信号的至少一个可植入传感器电路，被配置为提供抗心动过速起搏（ATP）治疗的治疗电路和控制器。控制器包括快速性心律失常检测电路和功效电路。快速心律失常检测电路被配置为使用电传感器信号检测受试者的快速性心律失常发作，并且确定快速性心律失常发作是否是可用ATP治疗的类型。功效电路被配置为估计当前配置的ATP治疗对受试者的功效，并且当估计的ATP治疗功效被认为不足时，控制器被配置为改变当前配置的ATP治疗的递送方案。描述了其他系统和方法。

76. 发明申请

US20070049976A1 Pacing management during cardiopulmonary resuscitation 有权
标题翻译：心肺复苏期间的起搏管理
公开(公告)号：US20070049976A1
公开(公告)日：2007-03-01
申请号：US11209975
申请日：2005-08-23
申请人： Quan Ni , Yanting Dong
发明人： Quan Ni , Yanting Dong
IPC分类号： A61N1/00
CPC分类号： A61N1/3962 , A61N1/36514 , A61N1/37 , G09B23/288
摘要： Systems and methods provide for coordinated cardiac pacing with delivery of cardiopulmonary resuscitation (CPR) to a patient. Managing cardiac pacing in a patient during a cardiac arrhythmia involves detecting a cardiac arrhythmia using a patient implantable medical device, prompting a cardiopulmonary resuscitation compression, and delivering, using the patient implantable medical device, a pacing pulse to a heart chamber in coordination with the compression prompt.
摘要翻译：系统和方法提供协调的心脏起搏和向患者输送心肺复苏（CPR）。在心律失常期间管理患者的心脏起搏包括使用患者可植入医疗装置检测心律失常，促使心肺复苏压缩，以及使用患者可植入医疗装置，与压缩器协调地向心室输送起搏脉冲提示。

77. 发明授权

US09008771B2 Non-captured intrinsic discrimination in cardiac pacing response classification 有权
标题翻译：心脏起搏反应分类中未被捕获的内在区别
公开(公告)号：US09008771B2
公开(公告)日：2015-04-14
申请号：US13411852
申请日：2012-03-05
申请人： Yanting Dong , Scott A. Meyer , Kevin John Stalsberg
发明人： Yanting Dong , Scott A. Meyer , Kevin John Stalsberg
IPC分类号： A61N1/37 , A61B5/0452
CPC分类号： A61N1/371 , A61B5/04525
摘要： Cardiac devices and methods discriminate non-captured intrinsic beats during evoked response detection and classification by comparing the features of a post-pace cardiac signal with expected features associated with a non-captured response with intrinsic activation. Detection of a non-captured response with intrinsic activation may be based on the peak amplitude and timing of the cardiac signal. The methods may be used to discriminate between a fusion or capture beat and a non-captured intrinsic beat. Discriminating between possible cardiac responses to the pacing pulse may be useful, for example, during automatic capture verification and/or a capture threshold test.
摘要翻译：心脏装置和方法通过将后期心脏信号的特征与与未捕获的应答相关联的预期特征与内在激活进行比较来区分诱发反应检测和分类期间的非捕获固有搏动。利用内在激活的非捕获响应的检测可以基于心脏信号的峰值振幅和定时。该方法可以用于区分融合或捕获节拍和未捕获的固有节拍。对起搏脉冲的可能的心脏反应之间的区分可能是有用的，例如在自动捕获验证和/或捕获阈值测试期间。

78. 发明授权

US08942791B2 Off-line sensing method and its applications in detecting undersensing, oversensing, and noise 有权
标题翻译：离线感测方法及其在检测不足，过流和噪声方面的应用
公开(公告)号：US08942791B2
公开(公告)日：2015-01-27
申请号：US13483387
申请日：2012-05-30
申请人： Yanting Dong , Shijie Zhang , Deepa Mahajan , Chenguang Liu , Dan Li , Yayun Lin , Derek D. Bohn
发明人： Yanting Dong , Shijie Zhang , Deepa Mahajan , Chenguang Liu , Dan Li , Yayun Lin , Derek D. Bohn
IPC分类号： A61B5/04 , A61N1/39
CPC分类号： A61B5/04012 , A61B5/0245 , A61B5/042 , A61B5/0452 , A61B5/7217 , A61N1/3704 , A61N1/3937
摘要： A system and method for performing independent, off-line evaluation of event sensing for collected electrograms, comprising: sensing an electrogram using an implantable medical device (IMD); determining locations of heart beats on at least one channel of the electrogram using a multi-pass process, resulting in a group of multi-pass beat locations; storing the electrogram and device-identified beat locations in a memory location; and retrieving the electrogram and device-identified beat locations from the memory location. The multi-pass process determines locations of heart beats on at least a first channel of the electrogram. The device-identified group of beat locations are then compared to the multi-pass group of beat locations identified using the multi-pass method. Based on the comparing step, oversensing of beats, undersensing of beats, or noise from the device can be detected.
摘要翻译：一种用于对收集的电描记图执行事件感测的独立离线评估的系统和方法，包括：使用可植入医疗装置（IMD）感测电描记图; 使用多遍处理确定心电图的至少一个通道上的心跳位置，从而产生一组多通拍位置; 将电描记图和设备识别的节拍位置存储在存储器位置中; 以及从存储器位置检索电描记图和设备标识的拍摄位置。多遍处理确定心电图的至少第一个通道的位置。然后将设备识别的拍摄位置组与使用多遍方法识别的拍摄位置的多通道组进行比较。基于比较步骤，可以检测节拍过度，节拍不足或来自装置的噪音。

79. 发明申请

US20130261476A1 PHRENIC NERVE STIMULATION DETECTION 有权
标题翻译：腓肠神经刺激检测
公开(公告)号：US20130261476A1
公开(公告)日：2013-10-03
申请号：US13781177
申请日：2013-02-28
申请人： Holly Rockweiler , Sunipa Saha , Yanting Dong
发明人： Holly Rockweiler , Sunipa Saha , Yanting Dong
IPC分类号： A61B5/04
CPC分类号： A61B5/04001 , A61B5/1107 , A61B5/4052 , A61B5/686 , A61B5/7217 , A61B5/7221 , A61B5/7246 , A61B2562/0219
摘要： In an example, a system includes a cardiac pulse generator configured to generate cardiac paces to pace the heart, a sensor configured to sense a physiological signal for use in detecting pace-induced phrenic nerve stimulation where the pace-induced phrenic nerve stimulation is phrenic nerve stimulation induced by electrical cardiac pace signals, and a phrenic nerve stimulation detector configured to analyze the sensed physiological signal to detect PS beats where the PS beats are cardiac paces that induce phrenic nerve stimulation. The detector may be configured to correlate signal data for sensed beat signals to a PS template to detect PS beats, or may be configured to analyze morphological features of sensed beat signals to detect PS beats, or may be configured to detect PS beats using a combination that both correlates signal data for sensed beat signals to a PS template and analyzes morphological features of sensed beat signals.
摘要翻译：在一个示例中，系统包括心脏脉冲发生器，其被配置为产生心脏步调以心跳，传感器被配置为感测生理信号，以用于检测步速诱发的膈神经刺激，其中步速诱发的膈神经刺激是膈神经由心脏心电图信号引起的刺激，以及膈神经刺激检测器，其被配置成分析感测到的生理信号以检测PS节拍，其中PS节拍是诱导膈神经刺激的心脏步。检测器可以被配置为将用于感测的拍频信号的信号数据与PS模板相关联以检测PS拍子，或者可以被配置为分析感测的拍子信号的形态特征以检测PS拍子，或者可以被配置为使用组合来检测PS拍子两者将感测到的拍频信号的信号数据相关联到PS模板并且分析感测到的拍频信号的形态特征。

80. 发明申请

US20130158615A1 RHYTHM DISCRIMINATION ENHANCEMENT - AV DRIVE 有权
标题翻译： RHYTHM歧视增强 - AV驱动
公开(公告)号：US20130158615A1
公开(公告)日：2013-06-20
申请号：US13765186
申请日：2013-02-12
申请人： Deepa Mahajan , Yanting Dong , David L. Perschbacher
发明人： Deepa Mahajan , Yanting Dong , David L. Perschbacher
IPC分类号： A61N1/362
CPC分类号： A61N1/3621 , A61B5/0464 , A61N1/3622 , A61N1/3624 , A61N1/3704 , A61N1/3962
摘要： An apparatus comprises an implantable cardiac signal sensing circuit and a controller circuit. The implantable cardiac signal sensing circuit provides a sensed depolarization signal from a ventricle and a sensed depolarization signal from an atrium. The controller circuit includes a one-to-one detector circuit and a tachyarrhythmia discrimination circuit. The one-to-one detector circuit measures cardiac depolarization intervals of the atrium and the ventricle and determines whether a relationship of atrial depolarizations to ventricular depolarizations is substantially one-to-one. The tachyarrhythmia discrimination circuit classifies the episode as VT when detecting a shortening or prolonging of a V-V interval that immediately precedes the same shortening or prolonging of an A-A interval.
摘要翻译：一种装置包括可植入心脏信号感测电路和控制器电路。可植入心脏信号感测电路提供来自心室的感测去极化信号和来自心房的感测去极化信号。控制器电路包括一对一检测器电路和快速心律失常鉴别电路。一对一检测器电路测量心房和心室的心脏去极化间隔，并确定心房去极化与心室去极化的关系是否基本上是一对一的。快速性心律失常辨别电路在检测到紧急或延长A-A间隔之前的V-V间隔的缩短或延长时，将该发作分类为VT。

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