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71. 发明授权

US07172603B2 Deployable constrictor for uterine artery occlusion 失效
标题翻译：子宫动脉闭塞可部分收缩
公开(公告)号：US07172603B2
公开(公告)日：2007-02-06
申请号：US10300495
申请日：2002-11-19
申请人： Fred H. Burbank , Michael L. Jones , Greig E. Altieri , Ed Olson
发明人： Fred H. Burbank , Michael L. Jones , Greig E. Altieri , Ed Olson
IPC分类号： A61B17/42
CPC分类号： A61B17/1227 , A61B5/026 , A61B8/06 , A61B8/12 , A61B17/1285 , A61B17/42
摘要： Devices, systems and methods for occluding blood vessels include a deployable constrictor having opposed pressure-applying portions, a delivery shaft configured to intravaginally advance the constrictor to the patient's cervix, a location sensor configured to detect a blood vessel, a deployment member for deploying the constrictor about the patient's cervix, and optionally a guide. The constrictor has a first configuration to receive a cervix and a second configuration to apply pressure to the cervical area to occlude a uterine artery by compression from the pressure-applying members. The pressure-applying members may be released from the cervix after a limited therapeutically effective time. The constrictor is for treating uterine disorders and conditions which may be treated by occlusion of the uterine arteries, such as uterine fibroids, dysfunctional uterine bleeding, post-partum hemorrhage, and bleeding associated with caesarian sections.
摘要翻译：用于闭塞血管的装置，系统和方法包括具有相对的压力施加部分的可展开的收缩器，配置成将阴囊推进到患者的子宫颈的输送轴，配置成检测血管的位置传感器，用于部署关于患者的子宫颈的收缩，以及可选的导引。收缩器具有接收子宫颈的第一构造和第二构造，以通过压力从压力施加构件压迫宫颈区域以阻塞子宫动脉。压力施加构件可在有限的治疗有效时间后从子宫颈释放。压缩器用于治疗可通过闭塞子宫动脉（例如子宫肌瘤），功能障碍性子宫出血，产后出血以及与切片相关的出血治疗的子宫疾病和病症。

72. 发明授权

US5980469A Method and apparatus for automated biopsy and collection of soft tissue 失效
标题翻译：用于软组织自动活检和收集的方法和装置
公开(公告)号：US5980469A
公开(公告)日：1999-11-09
申请号：US4782
申请日：1998-01-09
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.
摘要翻译：一种用于自动活检和收集软组织的方法和装置，其具有带有接收端口的穿刺针，以在切割之前捕获组织。马达驱动器将组织接收端口引导并定位在病变位置处，并且沿着装置的纵向轴线的任意位置。切割器进入接收室并切断已经脱垂到接收端口中的组织。然后将切断的组织从接收端口移除而不从病变部位移除穿刺针接收端口，从而允许仅用一个插入准确，快速地去除任意数量的芯样品。组织样品盒为样品提供储存，以及用于编码和解码获得样品的位置的装置。一起，这些特征允许对于大的病变进行更准确和完整的取样，用于由于各种原因完全去除小损伤或去除其他组织。

73. 发明授权

US5810806A Methods and devices for collection of soft tissue 失效
标题翻译：用于收集软组织的方法和装置
公开(公告)号：US5810806A
公开(公告)日：1998-09-22
申请号：US705622
申请日：1996-08-29
申请人： Mark A. Ritchart , Minh Tran , Mark Cole , Fred H. Burbank
发明人： Mark A. Ritchart , Minh Tran , Mark Cole , Fred H. Burbank
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/32 , A61B18/14 , A61B19/00 , A61B17/39
CPC分类号： A61B10/0266 , A61B18/1482 , A61B10/02 , A61B2017/0046 , A61B2017/00796 , A61B2017/32004 , A61B2018/00208 , A61B2018/1407 , A61B2018/1861 , A61B2090/062 , A61B2090/378 , A61B2090/3908
摘要： This invention provides an inventive tissue sampling probe which offers many advantages over probes available in the prior art. Unexpectedly superior results are obtained in connection with the retrieval of intact tissue specimens, because of a unique combination of cutting features, including, for example, the employment of an electrosurgical cutting element and a vacuum assist in one preferred embodiment. A particularly important feature of the invention is the ability to manipulate the electrosurgical cutting element to cleanly sever the distal end of the tissue specimen. In certain embodiments, this is accomplished without any cutting impact on surrounding tissue. The versatility of the invention permits its use in many applications, including, for example, breast biopsies, laparoscopic surgery, and lymphadenectomy procedures.
摘要翻译：本发明提供了一种创新的组织取样探针，其提供了优于现有技术中可用的探针的许多优点。由于在一个优选实施例中包括例如使用电外科切割元件和真空辅助的切割特征的独特组合，可以获得与完整组织标本的检索有关的意想不到的优异结果。本发明的一个特别重要的特征是能够操纵电外科切割元件来清洁地切断组织标本的远端。在某些实施方案中，这是在对周围组织没有任何切割冲击的情况下实现的。本发明的多功能性允许其在许多应用中使用，包括例如乳房活组织检查，腹腔镜手术和淋巴结清扫手术。

74. 发明授权

US5775333A Apparatus for automated biopsy and collection of soft tissue 失效
公开(公告)号：US5775333A
公开(公告)日：1998-07-07
申请号：US645225
申请日：1996-05-13
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.

75. 发明授权

US5769086A Control system and method for automated biopsy device 失效
标题翻译：自动活检装置的控制系统和方法
公开(公告)号：US5769086A
公开(公告)日：1998-06-23
申请号：US568143
申请日：1995-12-06
申请人： Mark A. Ritchart , Fred H. Burbank
发明人： Mark A. Ritchart , Fred H. Burbank
IPC分类号： A61B10/02 , A61B10/00 , A61B19/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2090/378 , A61B34/10 , A61B34/25 , A61B34/70
摘要： An automatic control system for a vacuum-assisted automatic core biopsy device (10) is provided, wherein the automatic core biopsy device (10) comprises a housing (12), out of which extends a needle assembly (14) including a hollow outer piercing needle (16), an inner cutter (18) having a lumen (20), a probe housing (22), and a tissue receiving notch (24). The automatic control system (92) is computerized to move the hollow outer piercing needle (16) automatically to the target tissue lesion, as was true in the prior art, but also is programmed to automatically control the rotational orientation of the piercing needle (16), and its associated tissue receiving notch (24), as well as the axial positioning and rotation of the cutting cannula (18). Consequently, a clinician user need only mark the desired locations within the target location from which tissue samples are desired and the automatic control system will operate the device to retrieve samples from the marked locations.
摘要翻译：提供了一种用于真空辅助自动核心活检装置（10）的自动控制系统，其中所述自动核心活检装置（10）包括壳体（12），所述壳体（12）从所述壳体（12）延伸出针组件（14），所述针组件包括中空外穿孔针（16），具有内腔（20）的内切割器（18），探针外壳（22）和组织接收凹口（24）。自动控制系统（92）被计算机化以将空心外穿刺针（16）自动移动到目标组织损伤，如现有技术中所述，但也被编程为自动控制穿刺针（16）的旋转取向）和其相关联的组织接收凹口（24）以及切割套管（18）的轴向定位和旋转。因此，临床医师用户仅需要在目标位置标记期望的位置，从该组织样本期望的位置，自动控制系统将操作该装置以从标记的位置检索样本。

76. 发明授权

US5526822A Method and apparatus for automated biopsy and collection of soft tissue 失效
公开(公告)号：US5526822A
公开(公告)日：1996-06-18
申请号：US217246
申请日：1994-03-24
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.

77. 发明授权

US08277391B2 Methods and devices for defining and marking tissue 有权
标题翻译：用于定义和标记组织的方法和装置
公开(公告)号：US08277391B2
公开(公告)日：2012-10-02
申请号：US10213638
申请日：2002-08-07
申请人： Seth A. Foerster , Fred H. Burbank , Mark A. Ritchart , Elias A. Zerhouni
发明人： Seth A. Foerster , Fred H. Burbank , Mark A. Ritchart , Elias A. Zerhouni
IPC分类号： A61B10/00
CPC分类号： A61B19/54 , A61B10/0275 , A61B10/0283 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/3987 , Y10T24/4501
摘要： In order to later identify the location of a biopsy or surgery, various means and methods for permanently and non-surgically marking selected tissue in the human body are used. Later visualization of the markers is readily accomplished using state-of-the-art imaging systems.
摘要翻译：为了稍后识别活组织检查或手术的位置，使用用于永久地和非手术地标记人体中的选定组织的各种手段和方法。使用最先进的成像系统，很容易实现标记的可视化。

78. 发明授权

US07981050B2 Methods and devices for automated biopsy and collection of soft tissue 失效
标题翻译：用于自动活检和收集软组织的方法和装置
公开(公告)号：US07981050B2
公开(公告)日：2011-07-19
申请号：US11671500
申请日：2007-02-06
申请人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
发明人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
IPC分类号： A61B10/00 , A61B17/32
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.
摘要翻译：公开了用于执行经皮活检程序的仪器，其具有改善现有技术装置的功能和性能的有利特征。这些仪器包括两种类型的一次性装置，以及具有活性组织捕获能力的多用途装置。改进的特征包括在单次插入过程中检索和评估多个组织样本的能力，而不对样品进行物理处理，以及结构特征，例如模制的组织盒壳体，适合于不同组织环境的变体真空端口实施例，以及一种用于反吹仪器以去除生物碎屑的方法等。

79. 发明授权

US07875036B2 Short term treatment for uterine disorder 失效
标题翻译：短期治疗子宫功能障碍
公开(公告)号：US07875036B2
公开(公告)日：2011-01-25
申请号：US11256768
申请日：2005-10-24
申请人： Fred H. Burbank , Greig E. Altieri , Michael L. Jones , Ed Olson
发明人： Fred H. Burbank , Greig E. Altieri , Michael L. Jones , Ed Olson
IPC分类号： A61B17/42
CPC分类号： A61B17/42 , A61B17/12 , A61B17/282
摘要： A method and device for treating a female patient's uterine disorder by occluding one or both of the patient's uterine artery. The treatment involves occluding one or both of the patient's uterine arteries with an intravaginal device to form a thrombus within the occluded artery or arteries and administering an agent which will prolong the occlusion of the artery or arteries after removal of the occluding device or initiate or accelerate fibroid cell apoptosis (programmed cell death). The intravaginal device has a pair of pivotally connected occluding members, with at least one of the occluding member having a movable occluding element on a distal shaft section of the occluding member.
摘要翻译：一种用于通过闭塞患者的子宫动脉中的一者或两者来治疗女性患者的子宫疾病的方法和装置。该治疗涉及用阴道内装置阻塞患者的子宫动脉中的一者或两者，以在闭塞的动脉或动脉内形成血栓并施用一种药剂，其将在移除闭塞装置之后延长动脉或动脉的闭塞，或启动或加速纤维细胞凋亡（程序性细胞死亡）。阴道内装置具有一对枢转连接的闭塞构件，其中至少一个阻塞构件在闭塞构件的远侧轴部上具有可移动的闭塞元件。

80. 发明授权

US07686817B2 Occlusion device for asymmetrical uterine artery anatomy 失效
标题翻译：用于不对称子宫动脉解剖的闭塞装置
公开(公告)号：US07686817B2
公开(公告)日：2010-03-30
申请号：US10721857
申请日：2003-11-25
申请人： Fred H. Burbank , Greig E. Altieri , Michael L. Jones , Ed Olson
发明人： Fred H. Burbank , Greig E. Altieri , Michael L. Jones , Ed Olson
IPC分类号： A61B17/42
CPC分类号： A61B17/42 , A61B17/12 , A61B2017/2927 , A61B2017/2944 , A61B2017/4216 , A61B2017/4225
摘要： An occluding device is disclosed for occluding a female patient's uterine arteries which have unsymmetrical anatomy with respect to the patient's uterine cervix. The occluding device has a pair of pivotally connected occluding members, with at least one of the occluding member having a movable occluding element on a distal shaft section of the occluding member. The position and orientation of the occluding elements on the distal shaft sections may be adjusted by operative members on the proximal shaft sections of the occluding members to accommodate for asymmetrical uterine artery anatomy. The occluding elements have pressure applying surfaces with one or more blood flow sensors such as Doppler chips which help the physician to better identify the uterine artery and to monitor blood flow therein. A tenaculum-like guiding element configured to be secured within the patient's uterine cervix, may be provided to guide the occluding device to the patient's cervix.
摘要翻译：公开了一种闭塞装置，用于阻塞相对于患者的子宫颈具有不对称解剖结构的女性患者的子宫动脉。闭塞装置具有一对枢转连接的闭塞构件，其中至少一个阻塞构件在闭塞构件的远侧轴部上具有可移动的闭塞元件。封闭元件在远侧轴部分上的位置和取向可以通过闭塞构件的近侧轴部分上的操作构件来调节，以适应不对称的子宫动脉解剖。闭塞元件具有一个或多个血液流量传感器（例如多普勒碎片）的压力施加表面，其帮助医生更好地识别子宫动脉并监测其中的血液流动。构造成固定在患者子宫颈内的十字形引导元件可被设置成将闭塞装置引导到病人的子宫颈。

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