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71. 发明授权

US07353100B2 Method for effecting kickdown shift 有权
标题翻译：实施减速班的方法
公开(公告)号：US07353100B2
公开(公告)日：2008-04-01
申请号：US11147534
申请日：2005-06-08
申请人： Gang Chen , Aaron Pfadt
发明人： Gang Chen , Aaron Pfadt
IPC分类号： G06F19/00
CPC分类号： F16H61/0437 , F16H59/20 , F16H59/44 , F16H2059/385 , F16H2059/425 , Y10T477/693637
摘要： A method for effecting a kickdown shift in a transmission of an automotive vehicle controls turbine speed change based on a continuous desired acceleration calculation. The method determines an initial speed of a turbine that transmits torque between an engine and a plurality of gears through a plurality of releasing and engaging elements. A target speed of one of the plurality of gears is determined. A desired time required to increase the turbine speed to the target speed is determined. A desired acceleration of the turbine is calculated according to the initial speed, the target speed, and the desired time. Turbine speed change rate is controlled through controlling the clutch torque of one or more of the releasing and engaging elements based on the desired acceleration.
摘要翻译：用于实现机动车辆的变速器中的降档变速的方法基于连续期望的加速度计算控制涡轮机速度变化。该方法确定通过多个释放和接合元件在发动机和多个齿轮之间传递扭矩的涡轮机的初始速度。确定多个齿轮中的一个的目标速度。确定将涡轮速度增加到目标速度所需的期望时间。根据初始速度，目标速度和期望时间计算涡轮机的期望加速度。基于期望的加速度，通过控制一个或多个释放和接合元件的离合器扭矩来控制涡轮变速率。

72. 发明授权

US07292922B2 Target volume based torque phase control during upshift 有权
标题翻译：升档期间基于目标体积的扭矩相位控制
公开(公告)号：US07292922B2
公开(公告)日：2007-11-06
申请号：US11222066
申请日：2005-09-08
申请人： Gang Chen , Aaron Pfadt
发明人： Gang Chen , Aaron Pfadt
IPC分类号： G06F7/00
CPC分类号： F16H61/061 , Y10T477/693 , Y10T477/69377 , Y10T477/69383
摘要： A transmission control system includes a first gear engagement element that receives fluid and engages a first gear. An electromagnetic actuator selectively interrupts fluid flow to the first gear engagement element based on a duty cycle of a control signal. A control module adjusts the duty cycle so that a fluid flow rate continuously decreases as the first gear engagement element produces a first torque sufficient to hold the first gear. The flow rate is based on a first estimated volume of the fluid necessary for the first gear engagement element to produce the first torque. The control module computes a current volume of the fluid when the first gear engagement element produces the first torque. The control module adjusts a value of the first estimated volume for subsequent transmission control when a difference between the current volume and the first estimated volume is greater than a predetermined volume.
摘要翻译：变速器控制系统包括接收流体并与第一档啮合的第一齿轮啮合元件。电磁致动器基于控制信号的占空比选择性地中断流到第一齿轮啮合元件的流体流。控制模块调整占空比，使得当第一齿轮接合元件产生足以保持第一档位的第一扭矩时，流体流速连续减小。流量基于第一估计体积的第一齿轮接合元件产生第一扭矩所需的流体。当第一齿轮接合元件产生第一转矩时，控制模块计算流体的当前体积。当当前音量与第一估计音量之间的差大于预定音量时，控制模块调节用于后续发送控制的第一估计音量的值。

73. 发明申请

US20070225497A1 Chiral Tertiary Aminoalkylnaphthols 失效
标题翻译：手性三氨基烷基萘酚
公开(公告)号：US20070225497A1
公开(公告)日：2007-09-27
申请号：US11578708
申请日：2005-05-11
申请人： Albert Chan , Gang Chen , Rongwei Guo , Jing Wu
发明人： Albert Chan , Gang Chen , Rongwei Guo , Jing Wu
IPC分类号： C07F9/6512 , B01J31/12 , C07D233/96
CPC分类号： B01J31/2409 , B01J2231/44 , B01J2531/16 , B01J2531/821 , B01J2531/822 , B01J2531/824 , B01J2531/827 , B01J2531/828 , B01J2531/847 , C07F9/6512 , C07F15/0066
摘要： The present invention provides bipyrimidinyl diphosphine compounds of the formula wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R′ and R″ are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; or an enantiomer thereof; or an enantiomeric mixture thereof. The compounds of the formula (I) are chiral atropisomeric bipyrimidinyl diphosphine compounds and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions, e.g., in palladium catalyzed asymmetric allylic substitution reactions. The compounds of the present invention are easily accessible in high enantiomeric purity according to the methods disclosed herein.
摘要翻译：本发明提供下式的二嘧啶基二膦化合物其中R是任选取代的烷基，环烷基，芳基或杂芳基; R'和R“独立地是任选取代的烷基，环烷基，芳基或杂芳基; 或其对映体; 或其对映体混合物。式（I）的化合物是手性的不对称双嘧啶基二膦化合物，因此可以用作配体以产生手性过渡金属催化剂，其可以用于各种不对称反应，例如钯催化的不对称烯丙基取代反应。根据本文公开的方法，本发明的化合物可以以高对映体纯度容易地获得。

74. 发明申请

US20070074540A1 Process for making crystalline structures having interconnected pores and high refractive index contrasts 审中-公开
$Process for making crystalline structures having interconnected pores and high refractive index contrasts$
标题翻译：具有互连孔和高折射率对比的结晶结构的方法
公开(公告)号：US20070074540A1
公开(公告)日：2007-04-05
申请号：US11635440
申请日：2006-12-06
申请人： Gang Chen , Ronen Rapaport , Elsa Reichmanis , Shu Yang
发明人： Gang Chen , Ronen Rapaport , Elsa Reichmanis , Shu Yang
IPC分类号： C03B37/016
CPC分类号： C03B19/12 , C03B2201/58 , C03C11/00
摘要： Techniques for producing a glass structure having interconnected macroscopic pores, including providing a polymeric structure having interconnected macroscopic pores; providing polymerizable glass precursors; filling pores in the polymeric structure with the polymerizable glass precursors; polymerizing the polymerizable glass precursors to yield a filled polymeric structure; and decomposing the filled polymeric structure to produce a glass structure having interconnected macroscopic pores. Techniques for filling pores of such glass structure with a material having a high refractive index, and for then removing the glass structure. Structures can be produced having interconnected macroscopic pores and high refractive index contrasts, which can be used, for example, as photonic band gaps.
摘要翻译：用于生产具有互连的宏观孔的玻璃结构的技术，包括提供具有互连的宏观孔的聚合物结构; 提供可聚合玻璃前体; 用可聚合玻璃前体填充聚合物结构中的孔; 聚合可聚合的玻璃前体以产生填充的聚合物结构; 并分解填充的聚合物结构以产生具有互连的宏观孔的玻璃结构。用具有高折射率的材料填充这种玻璃结构的孔的技术，然后去除玻璃结构。可以制造具有互连的宏观孔和高折射率对比度的结构，其可以用作例如光子带隙。

75. 发明申请

US20060282804A1 NOVEL TEST STRUCTURE FOR AUTOMATIC DYNAMIC NEGATIVE-BIAS TEMPERATURE INSTABILITY TESTING 有权
标题翻译：自动动态偏差温度不稳定性测试的新型测试结构
公开(公告)号：US20060282804A1
公开(公告)日：2006-12-14
申请号：US11458345
申请日：2006-07-18
申请人： Chew Hoe Ang , Gang Chen , Shyue Seng Tan
发明人： Chew Hoe Ang , Gang Chen , Shyue Seng Tan
IPC分类号： G06F17/50
CPC分类号： H01L22/34 , G01R31/2628 , G01R31/2642 , H01L2924/0002 , H01L2924/00
摘要： The invention describes a novel test structure and process to create the structure for performing automatic dynamic stress testing of PMOS devices for Negative Bias Temperature Instability (NB TI). The invention consists of an integrated inverter, two integrated electronic switches for switching from stress mode to device DC characterization measurement mode, and a PMOS FET device under test (DUT). The inverter assures the proper 180 degree phase relationship between the test device source and gate voltage while the imbedded electronic switches provide isolation of the test device during DC characterization testing. Another embodiment of the invention enables the testing of multiple devices under test (DUTs).
摘要翻译：本发明描述了一种新颖的测试结构和工艺，以创建用于负偏压温度不稳定（NB TI）的PMOS器件的自动动态应力测试的结构。本发明由集成逆变器，用于从应力模式切换到器件直流表征测量模式的两个集成电子开关以及被测试的PMOS FET器件（DUT）组成。在DC特性测试期间，嵌入式电子开关提供测试设备的隔离，逆变器确保测试设备源和栅极电压之间正确的180度相位关系。本发明的另一实施例使得能够测试被测试的多个器件（DUT）。

76. 发明申请

US20060263331A1 Therapeutic use of tumor necrosis factor-alpha mutein 审中-公开
标题翻译：治疗性使用肿瘤坏死因子-α突变蛋白
公开(公告)号：US20060263331A1
公开(公告)日：2006-11-23
申请号：US10741161
申请日：2003-12-19
申请人： Gang Chen , Xinjiang Du , Dezheng Wu , Weijing Zhang , Shirley Chen
发明人： Gang Chen , Xinjiang Du , Dezheng Wu , Weijing Zhang , Shirley Chen
IPC分类号： A61K38/19 , A61K38/17 , A61K31/704 , A61K31/522 , A61K33/24
CPC分类号： A61K45/06 , A61K38/1816 , A61K38/191 , A61K38/193 , A61K38/2013 , A61K38/2026 , A61K38/208 , A61K38/21 , A61K2300/00
摘要： Improved methods for treating neoplastic diseases such as cancer are provided by using muteins of human tumor necrosis factor-alpha (TNF-α). Compared to wild-type human TNF-α these therapeutic TNF muteins have higher specific anti-tumor activity, but with much reduced systemic toxicity and milder side effects such chills and fever. In addition, potentially synergistic, novel combinations of the inventive TNF-α muteins with other anti-neoplastic agents are provided for effectively treating patients having particular types of cancer or malignancy or at particular stages of cancer development, and for mitigating resistance of the patients to treatment of non-TNF antineoplastic agents.
摘要翻译：通过使用人肿瘤坏死因子-α（TNF-α）的突变蛋白来提供治疗肿瘤疾病如癌症的改进方法。与野生型人TNF-α相比，这些治疗性TNF突变蛋白具有更高的特异性抗肿瘤活性，但是具有大大降低的全身毒性和较轻的副作用，如发冷和发烧。另外，提供本发明的TNF-α突变蛋白与其它抗肿瘤剂的潜在协同，新颖的组合，用于有效治疗具有特定类型的癌症或恶性肿瘤或癌症发展的特定阶段的患者，并且为了减轻患者的耐药性治疗非TNF抗肿瘤药物。

77. 发明申请

US20060208223A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same 有权
公开(公告)号：US20060208223A1
公开(公告)日：2006-09-21
申请号：US11402693
申请日：2006-04-11
申请人： Gang Chen , Dan Fuchs , Ylva Olsson , Ronen Rapaport , Vlkram Sundar
发明人： Gang Chen , Dan Fuchs , Ylva Olsson , Ronen Rapaport , Vlkram Sundar
IPC分类号： G02B6/00 , G02B6/10
CPC分类号： B82Y15/00 , B82Y20/00 , B82Y30/00 , G02B1/04 , G02B1/045 , G02B6/138 , G02B2006/12097 , C08L27/12
摘要： The present invention relates to a polymeric composition of matter. The composition includes at least one polymer matrix and plurality of quantum dots distributed therein. The polymer may be a perfluorocyclobutane polymer having high optical transmission at telecommunications wavelengths. The quantum dots may include cap compounds to increase the solubility of the quantum dots in the composition. Typical cap compounds include aromatic organic molecules. Optical devices including waveguides may be fabricated from the polymeric compositions of the invention.

78. 发明申请

US20060070050A1 Method and apparatus for reducing instruction dependencies in extended SSA form instructions 失效
标题翻译：用于减少扩展SSA格式指令中的指令依赖性的方法和装置
公开(公告)号：US20060070050A1
公开(公告)日：2006-03-30
申请号：US10954586
申请日：2004-09-30
申请人： Gang Chen
发明人： Gang Chen
IPC分类号： G06F9/45
CPC分类号： G06F8/433 , G06F8/443
摘要： A method and apparatus for reducing instruction dependencies in extended SSA form instructions includes examining a first instruction of a worklist, wherein the worklist contains instructions in the extended SSA form that have a source, a previous link and a write mask and further produce an output. The method and apparatus further includes examining at least one second instruction of the worklist, wherein at least one second instruction is a source of the first instruction. Lastly, the method and apparatus includes translating the plurality of instructions in the worklist into a second plurality of instructions in the extended SSA form where the second plurality of instructions contains less instruction dependencies such as previous links.
摘要翻译：用于减少扩展SSA形式指令中的指令依赖性的方法和装置包括检查工作列表的第一指令，其中工作列表包含具有源，先前链接和写掩码的扩展SSA形式的指令，并进一步产生输出。该方法和装置还包括检查工作列表的至少一个第二指令，其中至少一个第二指令是第一指令的源。最后，所述方法和装置包括将工作列表中的多个指令转换成扩展SSA形式的第二多个指令，其中第二多个指令包含较少的指令依赖性，例如先前的链接。

79. 发明申请

US20050186623A1 Isolating cells expressing secreted proteins 审中-公开
公开(公告)号：US20050186623A1
公开(公告)日：2005-08-25
申请号：US11099158
申请日：2005-04-05
申请人： James Fandl , Neil Stahl , Gang Chen , George Yancopoulos
发明人： James Fandl , Neil Stahl , Gang Chen , George Yancopoulos
IPC分类号： A01K67/027 , C07K14/315 , C07K14/52 , C07K16/28 , C12N5/10 , C12N15/09 , C40B30/04 , G01N33/569 , G01N33/68 , C12Q1/68 , G01N33/53 , G01N33/567
CPC分类号： C40B30/04 , A01K2217/05 , A01K2267/01 , C07K14/315 , C07K14/52 , C07K16/2863 , C07K2317/77 , C07K2319/00 , C12N15/1051 , G01N33/56966 , G01N33/6845 , G01N2500/10
摘要： A method for identifying and isolating cells which produce secreted proteins. This method is based upon a specific characteristic or the expression level of the secreted protein by transiently capturing the secreted protein on the surface of an individual cell, allowing selection of rare cell clones from a heterogeneous population. Also provided is the use of this method to generate cells which produce a desired level of secreted protein or secreted protein of a particular characteristic(s), and organisms which possess such cells. In particular, the method allows rapid isolation of high expression recombinant antibody-producing cell lines, or may be applied directly to rapid isolation of specific hybridomas, or to the isolation of antibody-producing transgenic animals. This method is applicable for any cell which secretes protein.

80. 发明申请

US20050111510A1 Corner-pumping method and gain module for solid state slab laser 有权
标题翻译：固态平板激光器的角抽法和增益模块
公开(公告)号：US20050111510A1
公开(公告)日：2005-05-26
申请号：US10719072
申请日：2003-11-21
申请人： Mali Gong , Chen Li , Qiang Liu , Ping Yan , Gang Chen , HaiTao Zhang , Ruizhen Cui
发明人： Mali Gong , Chen Li , Qiang Liu , Ping Yan , Gang Chen , HaiTao Zhang , Ruizhen Cui
IPC分类号： H01S3/042 , H01S3/06 , H01S3/09 , H01S3/0941 , H01S3/16
CPC分类号： H01S3/0606 , H01S3/042 , H01S3/0615 , H01S3/08095 , H01S3/094057 , H01S3/0941 , H01S3/1611 , H01S3/1643 , H01S3/2316
摘要： A corner-pumping method for slab laser and a solid-state laser gain module are disclosed. In one embodiment, said method comprises directing a pump light into a laser slab through slab corners of said laser slab; propagating the pump light within the laser slab by total internal reflection (TIR); and substantially absorbing the pump light during propagating. In another embodiment, said gain module comprises a laser slab formed by a solid state laser material, said laser slab including slab corners with corner faces; and a pump source providing a pump light; wherein said pump light is directed into said laser slab through said slab corners of said laser slab, propagated within said laser slab by total internal reflection (TIR), and substantially absorbed during propagation; and wherein said laser slab outputs an amplified laser beam.
摘要翻译：公开了一种用于平板激光器和固态激光增益模块的角式抽取方法。在一个实施例中，所述方法包括将泵浦光通过所述激光板的板角引导到激光板中; 通过全内反射（TIR）传播激光板内的泵浦光; 并且在传播期间基本上吸收泵浦光。在另一个实施例中，所述增益模块包括由固体激光材料形成的激光平板，所述激光板包括具有角面的平板角; 以及提供泵浦光的泵浦源; 其中所述泵浦光通过所述激光板的所述板角转入所述激光板，通过全内反射（TIR）在所述激光板内传播，并且在传播期间基本上被吸收; 并且其中所述激光板输出放大的激光束。

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