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71. 发明申请

US20060165811A1 Method and system for automatic decoding of motor cortical activity 审中-公开
标题翻译：运动皮质活动自动解码方法及系统
公开(公告)号：US20060165811A1
公开(公告)日：2006-07-27
申请号：US11086956
申请日：2005-03-22
申请人： Michael Black , Frank Wood , Wei Wu
发明人： Michael Black , Frank Wood , Wei Wu
IPC分类号： A61K35/30
CPC分类号： G06K9/00536 , A61B5/0476 , A61B5/4041 , A61B5/7267
摘要： A Switching Kalman Filter Model for the real-time inference of hand kinematics from a population of motor cortical neurons. Firing rates are modeled as a Gaussian mixture where the mean of each Gaussian component is a linear function of hand kinematics. A “hidden state” models the probability of each mixture component and evolves over time in a Markov chain. Gaussian mixture models and Expectation Maximization (EM) techniques are extended for automatic spike sorting. Good initialization of EM is achieved via spectral clustering. To account for noise, the mixture model is extended to include a uniform outlier process. A greedy optimization algorithm that selects models with different numbers of neurons according to their decoding accuracy is used to automatically determine the number of neurons recorded per electrode. Closed loop neural control of external events are demonstrated using neural control of a computer curser.
摘要翻译：一种切换卡尔曼滤波器模型，用于从运动皮层神经元群体的手运动学的实时推断。发射速率被模拟为高斯混合，其中每个高斯分量的平均值是手动运动学的线性函数。 “隐藏状态”模拟了马可夫链中每个混合分量的概率随时间推移。高斯混合模型和期望最大化（EM）技术被扩展用于自动尖峰分类。通过光谱聚类实现EM的良好初始化。为了解决噪音，混合模型被扩展到包括一个统一的离群过程。使用根据其解码精度选择具有不同数目神经元的模型的贪心优化算法来自动确定每个电极记录的神经元数量。外部事件的闭环神经控制使用计算机光标的神经控制进行演示。

72. 发明授权

US07056318B2 Temperature controlled heating device and method to heat a selected area of a biological body 有权
标题翻译：温度控制加热装置和加热生物体的选定区域的方法
公开(公告)号：US07056318B2
公开(公告)日：2006-06-06
申请号：US10121236
申请日：2002-04-12
申请人： Michael Black
发明人： Michael Black
IPC分类号： A61B18/18
CPC分类号： A61B18/00 , A61B18/12 , A61B18/20 , A61B2017/0007 , A61B2017/00084
摘要： A heating device and method are provided that control a temperature in a selected area of a body part to obtain a temperature effect within the selected area for therapeutic or medical purposes. It includes temperature generating means to generate a temperature in the selected area. It also includes temperature detecting means to detect the generated temperature from the selected area. It further includes temperature controlling means to control the temperature generating means to maintain the generated temperature within a range of a desired temperature. The device and method prevent irreversibly damaging or overheating the selected area or the tissue surrounding the selected area. It is advantageous to applications where there is a need to accurately control the temperature in a selected area in a biological body, for instance, to activate or evaporate a temperature sensitive agent in the selected area.
摘要翻译：提供一种加热装置和方法，其控制身体部位的选定区域中的温度以获得用于治疗或医疗目的的所选区域内的温度效应。它包括在所选区域中产生温度的温度发生装置。它还包括温度检测装置，用于检测所选区域产生的温度。还包括温度控制装置，用于控制温度发生装置，以将发生的温度保持在所需温度的范围内。该装置和方法防止选定区域或所选区域周围的组织不可逆地损坏或过热。有必要精确地控制生物体内选定区域的温度，例如激活或蒸发选定区域中的温度敏感剂的应用。

73. 发明授权

US5479543A Precision light-guiding terminal for optical fibers 失效
标题翻译：光纤精密导光端子
公开(公告)号：US5479543A
公开(公告)日：1995-12-26
申请号：US252913
申请日：1994-06-02
申请人： Michael Black
发明人： Michael Black
IPC分类号： A61B18/22 , G02B6/26
CPC分类号： G02B6/262 , A61B18/22
摘要： A precision light-guiding terminal for optical fibers or optical fiber bundles consisting of a terminal (34) with an insertion duct (28) for receiving the end portion of an optical fiber (20) or optical fiber bundle (52), an input face (30) for in-coupling of a light (38) guided by the optical fiber (20) or optical fiber bundle (52), a light-guiding tip (40) for shaping guiding and performing optical operations on the light (38), and an output face (42) for out-coupling of the light (38).
摘要翻译：一种用于光纤或光纤束的精密光导端子，包括具有用于接收光纤（20）或光纤束（52）的端部的插入导管（28）的端子（34），输入面（30），用于使由所述光纤（20）或光纤束（52）引导的光（38）进行插入耦合;导光头（40），用于对所述光（38）引导和执行光学操作，，以及用于光（38）的输出耦合的输出面（42）。

74. 发明授权

US5420882A Infrared CO.sub.2 laser with a blue-green aiming beam 失效
标题翻译：带有蓝绿色瞄准光束的红外CO2激光器
公开(公告)号：US5420882A
公开(公告)日：1995-05-30
申请号：US255437
申请日：1994-06-08
申请人： Michael Black
发明人： Michael Black
IPC分类号： B23K26/02 , B23K26/06 , H01S3/08
CPC分类号： B23K26/0604
摘要： An apparatus confocally delivers to an object an infrared CO.sub.2 laser beam and a highly visible (e.g., blue-green) aiming beam. The beams from the two lasers are coaxially superimposed by means of a plate which transmits visible light and reflects infrared light. The resulting two coaxial beams are then guided to the object by means of reflective surfaces. Reflective beam guidance provides coincident focus of the infrared and aiming beams with unprecedented precision and also permits the combination of an infrared beam with a highly visible aiming beam.
摘要翻译：一种装置将红外CO 2激光束和高度可见（例如蓝 - 绿）瞄准光束共同传送给物体。来自两个激光器的光束通过透射可见光并反射红外光的板同轴地叠加。然后通过反射表面将所得到的两个同轴光束引导到物体。反射光束引导提供了前所未有的精度的红外和瞄准光束的重合焦点，并且还允许红外光束与高度可见的瞄准光束的组合。

75. 发明授权

US5163936A Endoscopic mirror laser beam delivery system and method for controlling alignment 失效
标题翻译：内镜镜激光束输送系统及对准方法
公开(公告)号：US5163936A
公开(公告)日：1992-11-17
申请号：US643279
申请日：1991-01-22
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： A61B18/20
CPC分类号： A61B18/201
摘要： An endoscopic mirror laser beam delivery system, e.g., for laser surgery, comprises a beam splitting module (22) for optical connection to a laser beam source (14) which supplies a low-power aiming beam (12) and a high-power surgical beam (10) to the splitting module (22); a two-mirror focusing unit (24) optically connected to the splitting unit (22); and an endoscopic tube (20) for guiding the beams focused by the focusing unit (24) to a target point (P). The system also comprises a method for checking alignment of the optical system by observing the positions of two visible beam spots. In case of misalignment, these two spots do not coincide in a single point, thereby indicating misalignment which can be then corrected. The system and the method eliminate central obscuration and misalignment of the laser beams on an operation site, thereby enabling a surgeon to be able to be confident that the surgeon beam will impinge precisely upon the spot delineated by the aiming beam.
摘要翻译：用于激光手术的内窥镜镜激光束传送系统包括用于光学连接到激光束源（14）的分束模块（22），激光束源（14）提供低功率瞄准光束（12）和大功率手术光束（10）到分束模块（22）; 光学连接到分离单元（22）的双镜像聚焦单元（24）; 以及用于将由聚焦单元（24）聚焦的束引导到目标点（P）的内窥镜管（20）。该系统还包括通过观察两个可视光束点的位置来检查光学系统的对准的方法。在未对准的情况下，这两个点在单个点处不一致，从而指示可以被校正的未对准。该系统和方法消除了操作现场上的激光束的中心遮蔽和不对准，从而使外科医生能够确信外科医生光束将精确地撞击在由瞄准光束描绘的光点上。

76. 发明授权

US5129883A Catheter 失效
标题翻译：导管
公开(公告)号：US5129883A
公开(公告)日：1992-07-14
申请号：US736373
申请日：1991-07-26
申请人： Michael Black
发明人： Michael Black
IPC分类号： A61F2/958 , A61M29/02
CPC分类号： A61M25/1011 , A61M2025/1052 , A61M2025/1095
摘要： A catheter adapted to be inserted into and advanced through a patient's circulatory system or through any other hollow conduit of the body is disclosed. The catheter of the present invention comprises a shunt section incorporating an elongated conduit having an open, distal end and a closure intermediate the open distal end and the outer terminal end of the catheter. A first inflatable cuff is located at the distal end of the tube while a second cuff is located at a predetermined distance from the first cuff, between the distal end and the closure of the shunt section. A pair of radiographic markers assist in the proper positioning of the cuffs. Means are provided to allow the blood to exit the tube near the proximal end thereof. Inflating and deflating means for the cuffs are also provided.
摘要翻译：公开了一种适于插入患者的循环系统或通过身体的任何其他中空导管进入并进入的导管。本发明的导管包括一个分流段，该分流段结合了一个细长导管，该导管具有开口的远端，以及在导管的开口远端和外端终端之间的中间。第一可充气袖带位于管的远端，而第二袖带位于离开第一袖带的预定距离处，位于分流段的远端和封闭件之间。一对放射照相标记有助于袖口的正确定位。提供装置以允许血液在其近端附近离开管。还提供了用于袖口的充气和放气装置。

77. 发明授权

US5114218A Liquid crystal sunglasses with selectively color adjustable lenses 失效
标题翻译：液晶太阳镜配有选择性颜色可调透镜
公开(公告)号：US5114218A
公开(公告)日：1992-05-19
申请号：US640042
申请日：1991-01-11
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： G02C7/10 , G02C7/12 , G02F1/133 , G02F1/23
CPC分类号： G02C7/101 , G02C7/12 , G02F1/13306 , G02F1/23
摘要： LC sunglasses with selectively color adjustable lenses comprising an energy cell (30) attached to one butt-strap (22) of a rim (10), a color changing switch (28) supported by another butt-strap (24), a memory chip (26) supported by a bridge portion (16) of the glasses rim, and lenses (12 and 14) of a laminated structure. Each lens consists of a color mosaic mask (43), an input polarizing plate (44), a liquid crystal cell (50) sandwiched between voltage-controlled active matrices (52a and 52b), and an output polarizing plate (46). When the wearer of the sunglasses wants to change the color of the lenses (12 and 14), he/she installs the switch (28) into the position of a selected color, whereby the battery cell (30) is electrically connected with respective pixel sets of the active matrices (52a and 52b) via the memory chip (26). As a result, the lenses will pass only the component of the white light (W) which corresponds to the selected color.
摘要翻译：具有选择性颜色可调透镜的LC太阳镜，包括附接到边缘（10）的一个对接带（22）的能量单元（30），由另一个对接带（24）支撑的变色开关（28），存储芯片（26），由玻璃边缘的桥接部分（16）支撑，以及层叠结构的透镜（12和14）。每个透镜由夹在电压控制的有源矩阵（52a和52b）之间的彩色马赛克掩模（43），输入偏振片（44），液晶单元（50）和输出偏振片（46）组成。当太阳镜的穿戴者想要改变透镜（12和14）的颜色时，他/她将开关（28）安装到所选颜色的位置，由此电池单元（30）与相应的像素电连接经由存储芯片（26）的有源矩阵（52a和52b）的集合。结果，透镜将仅通过对应于所选颜色的白光（W）的分量。

78. 发明授权

US4361531A Container molding and trimming method and apparatus 失效
标题翻译：集装箱成型和修边方法和装置
公开(公告)号：US4361531A
公开(公告)日：1982-11-30
申请号：US305158
申请日：1981-09-24
申请人： Michael Black
发明人： Michael Black
IPC分类号： B29C49/72 , B29C49/74 , B29C17/12
CPC分类号： B29C49/74 , B29C49/72 , Y10T225/343
摘要： A method and apparatus for molding plastic containers and the like and for removing unwanted flash material therefrom. In the molding step, an unwanted tail flash portion is molded to have a weakened area along the line of attachment to the bottom of the container. After ejection from the mold, the container is conveyed to a tail removal device that grips and tears the tail free from the container along the weakened line area by a downward and rearward force.
摘要翻译：用于模制塑料容器等并用于从其中去除不想要的闪光材料的方法和装置。在模制步骤中，不想要的尾部闪光部分被模制成具有沿着与容器底部的连接线的弱化区域。在从模具中弹出之后，容器被传送到尾部移除装置，该装置通过向下和向后的力沿着弱化的线区域将容器沿着尾部免于撕裂和撕裂。

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