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    • 72. 发明申请
    • PROCESS FOR PREPARING 2-SUBSTITUTED BUT-2-ENE-1,4-DIAL-ACETALS AND NOVEL HEMIACETALS OF GLYOXALMONOACETALS
    • PROCESS FOR 2-取代前准备,-2-CN-1.4-DIAL -4-缩醛和半缩醛NEW乙二醛单缩醛
    • WO1998001439A1
    • 1998-01-15
    • PCT/EP1996002989
    • 1996-07-09
    • BASF AKTIENGESELLSCHAFT
    • BASF AKTIENGESELLSCHAFTFRANK, JürgenMELDER, Johann-PeterMERGER, FranzWITZEL, Tom
    • C07D319/06
    • C07D319/06C07D319/08Y02P20/584
    • The invention concerns a process for preparing 2-substituted but-2-ene-1,4-dial-acetals of general formula (I) in which the substituents R to R stand for hydrogen or C1-C6 aliphatic groups and R and R or R and R in each case are common members of an aliphatic 4- to 7-member ring which can contain a heteroatom, and in which R designates a C1-C12 alkyl, alkenyl or alkinyl group, which can be substituted by cycloaliphatic, aromatic or heterocyclic groups or by hydroxy, ether, thioether, acyl, alkylamino, carboxy or carbalkoxy groups, an optionally substituted aryl group or an alkoxy, alkylthio or acyloxy group. According to the invention: a) glyoxal is reacted with a 1,3-propane diol of general formula (II) in an aqueous solution in the presence of an acid to form a monoacetal of general formula (III), the reaction solution is neutralized and optionally the volatile components which are lighter than the monoacetal (III) are distilled off; b) the resultant monoacetal (III) is reacted with an aldehyde R -CHO in the presence of between 0.01 and 10 mol %, relative to glyoxal, of a catalyst mixture consisting of a secondary amine and an acid to form an aldol of general formula (IV), and optionally the volatile components which are lighter than the aldol (IV) are distilled off; and c) the aldol (IV) is dehydrogenated in the presence of a dehydrating agent to form product (I). The invention also concerns novel hemiacetals of glyoxalmonoacetals.
    • 制备2-取代的丁-2-烯-1,4-拨号通式(I)的4-缩醛,其中,所述取代基R <1>至R <4>是氢或C1-C6脂族基团 且R <2>和R <3>或R <1>和R <2>的脂族4-每个公共成员至7元环,该环可以含有杂原子是,且其中R <5>是烷基 - ,链烯基或具有可以通过脂环族,芳族或杂环基团或由羟基,醚,硫醚,酰基,烷基氨基,或Carboxi-烷基团取代的1〜12个碳原子的炔基,任选取代的 芳基或烷氧基,烷硫基或酰氧基,通过在酸的存在下水溶液反应,进行反应(a)中的乙二醛与通式(II)的1,3-丙二醇通式的单缩醛(III) 中和反应溶液,并任选地比单缩醛打火机(III)挥发性Bestandte ILE蒸馏出,(B),因此具有在0.01存在〜10摩尔%的醛 - [R <5> CHO获得的单缩醛III,基于乙二醛,仲胺和酸的催化剂混合物的一般的醛醇 式(IV)中,任选地蒸馏出比醛醇IV挥发的较轻,和(c)醛醇缩合(IV)是在脱水剂的存在下对产物脱水I,以及乙二醛单缩醛的新的半缩醛。
    • 75. 发明申请
    • CHIRAL DOPING AGENTS FOR LIQUID CRYSTALLINE MEDIA
    • 手性剂液晶MEDIA
    • WO1997049694A1
    • 1997-12-31
    • PCT/EP1997003044
    • 1997-06-12
    • BASF AKTIENGESELLSCHAFTVILL, VolkmarSCHIMMEL, UlrikeSIEMENSMEYER, Karl
    • BASF AKTIENGESELLSCHAFT
    • C07D319/06
    • C09K19/588C07D319/06C07F5/025C09B67/0098
    • The invention relates to compounds of general formula (I) in which the radicals: X is mutually independently boron; CH2 or (a), B is hydrogen, C1 to C8 alkyl, phenyl, biphenylyl or a radical of formula (II); A and A are spacers; n is 0, 1, 2 or 3; m is 1 of zero for X = CH2; M and M are possibly fluorine-, chlorine-, bromine-, cyano-, hydroxy- or nitro-substituted single or multi-nuclear aliphatic, aromatic, heteroaliphatic or heteroaromatic ring systems, the radicals Y are mutually independently a direct bond O, S, COO, OCO, OCOO, CON(R) or N(R)CO; Z and Z are polymerisable groups or hydrogen; R is hydrogen or C1 to C4 alkyl and R and R are hydrogen; possibly O, COO, OCO, OCOO or N(R)-interrupted C1 to C30 alkyl, C2 to C30 alkenyl, C1 to C30 alkanoyl or C3 to C30 alkenoyl or a radical of formula (III) where T is a direct compound, CO, CH2, CH=CH-CO, CH2CH2CO or SO2 and A, M, Y, Z, n and m have the meanings given. The compounds of the invention are suitable as e.g. chiral doping agents for electro-optical display components or for nematic or cholesteric liquid crystals for the generation of coloured reflecting coatings of the production of liquid crystalline cholesterically ordered pigments.
    • 本发明涉及通式(I),其中基团X独立地为硼,或CH 2(a)中,B是氢,C1-C8烷基,苯基,联苯基或下式基团(II),并且A的化合物 A <1>间隔,n为0,1,2或3,M = 1或X =多核CH2为零,m和m <1>任选地被氟,氯,溴,氰基,羟基或硝基取代的单 - 或脂族取代的 ,芳族,杂脂族或杂芳族环系统中,基团Y彼此独立地为直接键,O,S,COO,OCO,OCOO,CON(R)或N(R)CO,Z和Z <1>可聚合基团或氢,R的 是氢或C1至C4烷基,R <1>和R <2>为氢,任选被O,COO,OCO,OCOO或N(R)中断的C1-C30烷基,C2至C30烯基,C1 - 至C 30链烷酰基或C 3 -C 30链烯酰基或式的基团(III),其中,T是直接键,CO,CH 2,CH = CH-CO,CH2CH2CO或SO 2和一个,M,Y,Z ,n和m具有所指明的含义 有。 本发明的化合物是适合的,例如,是 作为电光学显示元件或用于生成反映在颜色或用于液晶的制备层向列型或胆甾型液晶手性掺杂剂胆甾醇排序的颜料。