会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 76. 发明授权
    • Polyvalent vaccine against diseases caused by papilloma viruses, method for the production and the use thereof
    • 针对由乳头瘤病毒引起的疾病的多价疫苗,其生产方法及其用途
    • US07320861B2
    • 2008-01-22
    • US10485454
    • 2002-07-26
    • Lutz GissmannKai PohlmeyerMartin Müller
    • Lutz GissmannKai PohlmeyerMartin Müller
    • C12Q1/68
    • C07K16/084A61K39/12C12N2710/20034
    • A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or a fragment thereof are injected into mammals, whereby in at least some of the expression vectors randomly generated heterologous sequences are inserted into the DNA code (b) serums are obtained from the mammals and these are tested for the presence of antibodies against particles of various papilloma virus types, and (c) using the serums tested, the structural protein gene clones are identified that code for a polyvalent vaccine, and (d) the vaccine is produced from them. Procedures for producing a vaccine is also described, together with its use for vaccination against diseases caused by papilloma viruses.
    • 在某些实施方案中描述了针对由乳头瘤病毒引起的疾病的疫苗,以及可通过以下方法获得的某些载体:(a)含有乳头状瘤病毒或其片段的结构蛋白的DNA编码的一种或多种表达载体 注射到哺乳动物中,由此在至少一些表达载体中随机产生的异源序列插入到DNA代码(b)中,从哺乳动物获得血清,并测试这些血清是否存在针对各种乳头状瘤病毒类型的颗粒的抗体, 和(c)使用测试的血清,鉴定编码多价疫苗的结构蛋白质基因克隆,和(d)从它们产生疫苗。 还描述了生产疫苗的程序,以及其用于针对由乳头瘤病毒引起的疾病的疫苗接种的用途。