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    • 71. 发明申请
    • STAGGERED CONTACT IMAGE SENSOR IMAGING SYSTEM
    • STAGGERED CONTACT图像传感器成像系统
    • WO2011143083A1
    • 2011-11-17
    • PCT/US2011/035679
    • 2011-05-09
    • ABBOTT LABORATORIESWANG, ShaohongGONZALEZ, Carlos Barnes
    • WANG, ShaohongGONZALEZ, Carlos Barnes
    • G01N21/64
    • G01N21/6458G01N21/64G01N2201/0806
    • A method and an apparatus for imaging a biologic sample is provided. The apparatus includes at least one light source, at least one lens array, at least one image detector, a positioning system, and an image processor. The lens array has a plurality of lengthwise extending rows, which rows are successively arranged in a widthwise direction. Each row has a plurality of micro lenses, with each micro lens having a resolution field. Each micro lens is adapted to receive light from the illuminated region of the sample and to produce a beam of light. Each row includes a first micro lens and the first micro lens in each successive row is offset from the first micro lens in the previous row by a predetermined amount extending in the lengthwise direction. The offset between successive rows aligns the resolution fields of the micro lenses to collectively create a continuous resolution field across the length of the lens array. The positioning system moves the lens array and image detector relative to the sample, or vice versa, or both. The image processor produces an image signal indicative of the illuminated region of the sample produced from data signals from the image detector.
    • 提供了一种生物样品成像方法和装置。 该装置包括至少一个光源,至少一个透镜阵列,至少一个图像检测器,定位系统和图像处理器。 透镜阵列具有多个纵向延伸的行,这些行在宽度方向上连续布置。 每行具有多个微透镜,每个微透镜具有分辨率场。 每个微透镜适于接收来自样品的照射区域的光并产生光束。 每行包括第一微透镜,并且每个连续行中的第一微透镜在前一行中偏离了在长度方向上延伸的预定量的第一微透镜。 连续行之间的偏移将微透镜的分辨率场对准以在透镜阵列的长度上共同形成连续的分辨率场。 定位系统相对于样品移动透镜阵列和图像检测器,反之亦然,或两者都相同。 图像处理器产生指示从图像检测器的数据信号产生的样本的照明区域的图像信号。
    • 72. 发明申请
    • SYSTEM AND METHOD FOR MAINTAINING AIR TEMPERATURE WITHIN A BUILDING HVAC SYSTEM
    • 在建筑暖通空调系统中维护空气温度的系统和方法
    • WO2011041408A2
    • 2011-04-07
    • PCT/US2010/050713
    • 2010-09-29
    • CARRIER CORPORATIONGRABON, MichelYUAN, ShuiKUANG, YuHuiLUO, DongOGGIANU, Stella M.
    • GRABON, MichelYUAN, ShuiKUANG, YuHuiLUO, DongOGGIANU, Stella M.
    • F24F11/02F24D15/04F25B30/02F24F3/052
    • F25B49/02F24D5/04F24D5/12F24D19/1087F24F3/08F24F2203/02F24H4/04F24H6/00F25B13/00F25B29/003F25B2400/06F25B2400/24
    • A system and method for conditioning air within an air handling system of a building is provided. The building has a hot water source and a cold water source. The conditioning system includes at least one heating-cooling unit connected to the air handling system, a primary water storage device, at least one heat pump, and a controller. The heating-cooling unit, which includes at least one chilled beam, is operable to transfer heat into or out of air passing within the air handling system of the building. The primary water storage device is operable to store a volume of water within a predetermined temperature range. The primary water storage device is in communication with the hot water source and the cold water source. The heat pump is connected to the primary water storage device and the chilled beam. The controller is adapted to selectively drive the heat pump to transfer heat between the primary water storage device and the chilled beam. The controller is also adapted to selectively control the system to transfer heat into or out of the primary water storage device to maintain the water within the primary storage device within the predetermined temperature range.
    • 提供了一种用于调节建筑物的空气处理系统内的空气的系统和方法。 该建筑物具有热水源和冷水源。 调节系统包括连接到空气处理系统的至少一个加热冷却单元,初级储水装置,至少一个热泵和控制器。 包括至少一个冷却梁的加热冷却单元可操作以将热量传送到通过建筑物的空气处理系统内的空气或从其中排出。 一次蓄水装置可操作以将一定体积的水储存在预定的温度范围内。 初级储水装置与热水源和冷水源连通。 热泵连接到初级储水装置和冷冻梁。 控制器适于选择性地驱动热泵以在主储水装置和冷冻梁之间传递热量。 控制器还适于选择性地控制系统以将热量传入或流出主要储水装置,以将主存储装置内的水保持在预定温度范围内。
    • 75. 发明申请
    • METHOD AND REAGENTS FOR DETECTING THE PRESENCE OR ABSENCE OF STAPHYLOCOCCUS AUREUS IN A TEST SAMPLE
    • 检测测试样品中存在或不存在白花菜的方法和试剂
    • WO2010151764A1
    • 2010-12-29
    • PCT/US2010/039987
    • 2010-06-25
    • PILOTS POINT LLCEDBERG, Stephen C.
    • EDBERG, Stephen C.
    • C12Q1/14
    • C12Q1/14
    • A presence/absence test for Staphylococcus aureus (S. aureus) involves placing a first generation test sample in a solution that will clot in the presence of S. aureus. The solution contains components that will selectively grow S. aureus and also contains clotting factors that will react with S. aureus, if S. aureus is present in the sample, to clot the solution. Examples of specimen samples that can be tested include nasal swabs and lesion swabs, among others. The test can also be modified to detect the presence or absence of methicillin resistant S. Aureus (MRSA). The addition of micro particles having a size in the range of about 0.1 micron to about 1.0 mm provides localities where the bacteria agglomerate, thereby significantly decreasing the clotting time, and providing a significantly stronger clot. The micro particles can be used in other bacteria tests to accelerate the production of an end result. Such other tests can include a vancomycin-resistant enterococcus test; a Group B Streptococcus test; a test for hemolytic E. coli; and a test for Listeria monocytogenes, to name a few. These tests are all performed in a liquid broth-type reagent mixture and do not necessarily involve clotting of the broth.
    • 金黄色葡萄球菌(金黄色葡萄球菌)的存在/不存在测试涉及将第一代测试样品置于在金黄色葡萄球菌存在下凝结的溶液中。 该溶液含有选择性生长金黄色葡萄球菌的成分,并且还含有凝血因子,如果金黄色葡萄球菌存在于样品中,则会与金黄色葡萄球菌发生反应,以凝固溶液。 可以测试的标本样品的实例包括鼻拭子和病变拭子等。 也可以修改测试以检测耐甲氧西林金黄色葡萄球菌(MRSA)的存在或不存在。 加入尺寸在约0.1微米至约1.0毫米范围内的微粒提供了细菌聚集的地方,从而显着降低凝固时间,并提供明显更强的凝块。 微粒可用于其他细菌测试,以加速最终结果的产生。 这样的其他测试可以包括耐万古霉素肠球菌测试; B组链球菌试验; 溶血性大肠杆菌检测; 和单核细胞增多性李斯特氏菌的检测,仅举几例。 这些测试都是在液体肉汤型试剂混合物中进行的,并不一定涉及肉汤的凝结。
    • 76. 发明申请
    • METHOD FOR ADDING SENSORY CONDITIONING CUES IN A PHARMACOTHERAPEUTIC REGIMEN
    • 用于在药物治疗方案中添加感觉调节蛋白的方法
    • WO2010075415A1
    • 2010-07-01
    • PCT/US2009/069245
    • 2009-12-22
    • LEVINE, Joshua, D.LEVINE, Robert, A.
    • LEVINE, Joshua, D.LEVINE, Robert, A.
    • A61K9/00
    • A61K9/4808
    • A method for administering pharmaceutical agents to a subject is provided. The method includes the steps of: a) providing a course of treatment for a subject, which course includes periodically administering an amount of medicine to the subject, which amount of medicine includes a dose of at least one active pharmacological agent (APA) and an amount of at least one non-active pharmacological agent (NPA), which NPA provides at least one non-visual sensory cue; and b) varying the dosage amount of the APA within the periodically administered amount of medicine, while the amount of the NPA contained within each periodically administered amount of medicine is provided at a level that maintains the sensory cue at a substantially constant level.
    • 提供了向受试者施用药剂的方法。 该方法包括以下步骤:a)为受试者提供治疗过程,该过程包括向对象周期性地施用一定量的药物,该药物量包括至少一种活性药理学剂(APA)和 至少一种非活性药理学剂(NPA)的量,其中NPA提供至少一种非视觉感觉提示; 和b)在周期性给药量的药物内改变APA的剂量,而在每个周期性给药量的药物中所含的NPA的量提供在将感觉提示保持在基本恒定水平的水平。
    • 77. 发明申请
    • METHOD AND APPARATUS FOR MAKING A WATER CUT DETERMINATION USING A SEQUESTERED LIQUID-CONTINUOUS STREAM
    • 使用序列液相连续流进行水切割测定的方法和装置
    • WO2009149361A1
    • 2009-12-10
    • PCT/US2009/046424
    • 2009-06-05
    • EXPRO METERS, INC.GYSLING, Daniel, L.
    • GYSLING, Daniel, L.
    • G01F1/66G01F1/74G01F5/00
    • G01F1/74G01F1/36G01F1/668
    • An apparatus and method for determining the water cut value of a multiphase fluid flowing within a pipe is provided. The device includes a sequestering structure disposed within the pipe, a transmitting device, a receiving device, and a processing device. The sequestering structure at least partially defines a sensing passage within the pipe, which passage has a gap extending substantially normal to a direction of fluid flow within the pipe. The sensing passage is oriented to sequester an amount of a liquid component of the multi-phase fluid sufficient to form a continuous liquid body extending across the gap of the sensing passage. The transmitting device is operable to transmit a signal through the liquid across the gap of the sensing passage. The receiving device is operable to receive the signal after it has traversed the liquid within the sensing passage, and create sensor data. The processing device is in communication with at least the receiving device to receive and process the sensor data to determine the water cut value of the liquid.
    • 提供一种用于确定在管内流动的多相流体的水分值的装置和方法。 该设备包括设置在管道内的隔离结构,发送设备,接收设备和处理设备。 隔离结构至少部分地限定了管道内的感测通道,该通道具有基本上垂直于管道内的流体流动方向延伸的间隙。 感测通道被取向为隔离足以形成延伸穿过感测通道的间隙的连续液体的多相流体的液体组分的量。 发射装置可操作以通过穿过感测通道的间隙的液体传输信号。 接收装置可操作以在信号已经穿过感测通道中的液体之后接收信号,并且产生传感器数据。 处理装置至少与接收装置通信以接收和处理传感器数据,以确定液体的水分值。
    • 78. 发明申请
    • CLAMP-ON APPARATUS FOR MEASURING A FLUID FLOW THAT INCLUDES A PROTECTIVE SENSOR HOUSING
    • 用于测量包含保护传感器外壳的流体流量的夹持装置
    • WO2009126956A1
    • 2009-10-15
    • PCT/US2009/040360
    • 2009-04-13
    • EXPRO METERS, INC.GYSLING, Daniel
    • GYSLING, Daniel
    • G01F1/66
    • G01F1/667G01F1/662
    • An apparatus for measuring one or more characteristics of a fluid flowing within a pipe is provided. The apparatus includes a housing, sealant, and an array of at least two ultrasonic sensors. The housing is operable to be mounted on the exterior surface of the pipe. The housing has at least one pocket extending between a pipe-side surface and an outer surface. The pipe-side surface mates with the exterior surface of the pipe. The sealant is disposed between the pipe exterior surface and the housing pipe-side surface. The sealant forms a seal around the pocket when the housing is mounted on the exterior surface of the pipe. The array of ultrasonic sensor units are disposed within the at least one pocket. Each sensor unit includes a transmitter and a receiver. The transmitters are operable to transmit ultrasonic signals through the fluid flow within the pipe. The receivers are operable to receive signals from the transmitters.
    • 提供一种用于测量在管内流动的流体的一个或多个特性的装置。 该装置包括壳体,密封剂和至少两个超声波传感器的阵列。 壳体可操作地安装在管道的外表面上。 壳体具有在管侧表面和外表面之间延伸的至少一个袋。 管侧表面与管的外表面配合。 密封剂设置在管外表面和外壳管侧表面之间。 当壳体安装在管道的外表面上时,密封剂在袋周围形成密封。 超声波传感器单元的阵列设置在至少一个口袋内。 每个传感器单元包括发射器和接收器。 发射器可操作以通过管道内的流体流传输超声波信号。 接收器可操作以从发射机接收信号。
    • 79. 发明申请
    • METHOD FOR MEASURING THE AREA OF A SAMPLE DISPOSED WITHIN AN ANALYSIS CHAMBER
    • 用于测量在分析室中处理的样品的区域的方法
    • WO2009126800A1
    • 2009-10-15
    • PCT/US2009/040057
    • 2009-04-09
    • ABBOTT POINT OF CARE, INC.LALPURIA, Niten, V.WARDLAW, Stephen, C.
    • LALPURIA, Niten, V.WARDLAW, Stephen, C.
    • G01N15/14G06T7/00G06T7/60
    • G01N21/17G01N15/05G01N2015/055G06T7/0012G06T7/62G06T2207/10056G06T2207/10064G06T2207/30024Y10T436/11
    • A method for determining the area of an analysis chamber covered by a biologic fluid sample quiescently residing within the chamber is provided. The chamber has a first panel with an interior surface, and a second panel with an interior surface, both of which panels are transparent. The method includes the steps of: a) illuminating the sample residing within the analysis chamber at one or more wavelengths operable to highlight interfaces between the sample and air, and to highlight a constituent within the sample; b) imaging the sample along the one or more wavelengths, and producing image signals representative of the interaction of the one or more wavelengths with the sample; c) determining a location of at least one interface between the sample and air, using the image signals; d) determining a location of one or more constituents within the sample relative to the at least one sample-air interface using the image signals; and e) determining an area of the chamber containing the sample, using the location of the one or more constituents and the at least one sample-air interface.
    • 提供了一种用于确定由静止在腔室内的生物流体样品覆盖的分析室的面积的方法。 该室具有带内表面的第一面板和具有内表面的第二面板,两个面板都是透明的。 该方法包括以下步骤:a)以可操作以突出样品和空气之间的界面的一个或多个波长照亮驻留在分析室内的样品,并突出显示样品内的成分; b)沿着一个或多个波长对样本进行成像,并产生表示一个或多个波长与样本的相互作用的图像信号; c)使用图像信号确定样品和空气之间的至少一个界面的位置; d)使用所述图像信号,相对于所述至少一个采样空气接口确定所述样本内的一个或多个成分的位置; 以及e)使用所述一个或多个成分和所述至少一个样品 - 空气界面的位置来确定包含所述样品的所述室的面积。