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61. 发明授权

US06565868B1 Methods for microbiological control in aqueous systems 失效
标题翻译：水系统微生物控制方法
公开(公告)号：US06565868B1
公开(公告)日：2003-05-20
申请号：US09484938
申请日：2000-01-18
申请人： Jonathan N. Howarth , Christopher J. Nalepa , Michael J. Sanders , David L. Shelton
发明人： Jonathan N. Howarth , Christopher J. Nalepa , Michael J. Sanders , David L. Shelton
IPC分类号： A01N2534
CPC分类号： C02F1/50 , A01N43/50 , Y02W10/37 , A01N25/34 , A01N25/12 , A01N25/10 , A01N2300/00
摘要： Microbiological control in water systems is achieved with an amount,of 1,3-dibromo-5,5-dimethylhydantoin that is less than the amount of N,N′-bromochloro-5,5-dimethylhydantoin required to achieve the same degree of microbiological control. The methods of combating Escherichia coli and/or Enterococcus faecium in an aqueous medium, and biofilms such as formed by Pseudomonas aeruginosa on surfaces contacted by the aqueous medium, involve introducing into the medium a biocidally effective amount of 1,3-dibromo-5,5-dimethylhydantoin. A microbiological control agent for use in water in accordance with U.S. Environmental Protection Agency regulations is purveyed in containers of a water control agent comprising 1,3-dibromo-5,5-dimethylhydantoin, which containers bear a label having thereon dosage levels pursuant to requirements promulgated by the U.S. Environmental Protection Agency. The 1,3-dibromo-5,5-dimethylhydantoin is used or purveyed either as a product having a large average particle size (e.g., 175 microns or more) or in the form of a compacted product. The compacted product can be formed without using a binder where the average particle size of the 1,3-dibromo-5,5-dimethylhydantoin is about 175 microns or more. Alternatively, the compacted product can be formed using a micronized synthetic polyolefin-based hydrocarbon wax and/or a micronized synthetic polyfluorocarbon wax as a binder, provided the wax is compatible with the 1,3-dibromo-5,5-dimethylhydantoin. In this case, the average particle size can be in the range of about 20-600 microns. Similarly, the compacted product can be a product formed from 1,3-dibromo-5,5-dimethylhydantoin having an average particle size of at least 175 microns, using an amount of a saturated, normally solid, fatty amide as the binder.
摘要翻译：水体系中的微生物控制是用一定量的1,3-二溴-5,5-二甲基乙内酰脲来实现的，其量小于实现相同程度的微生物所需的N，N'-溴氯-5,5-二甲基乙内酰脲的量控制。在水性介质中防治大肠杆菌和/或屎肠球菌的方法以及由含水介质接触的表面上的铜绿假单胞菌形成的生物膜包括将生物有效量的1,3-二溴-5- 5-二甲基乙内酰脲。根据美国环境保护局规定在水中使用的微生物控制剂在含有1,3-二溴-5,5-二甲基乙内酰脲的水控制剂的容器中提供，该容器具有根据要求具有其剂量水平的标签由美国环保署颁布。 1,3-二溴-5,5-二甲基乙内酰脲作为具有大平均粒度（例如175微米或更大）的产品或以压制产品的形式使用或提供。可以不使用1,3-二溴-5,5-二甲基乙内酰脲的平均粒径为约175微米或更大的粘合剂来形成压制产品。或者，如果蜡与1,3-二溴-5,5-二甲基乙内酰脲相容，则可使用微粉化的合成聚烯烃基烃蜡和/或微粉化合成多氟碳蜡作为粘合剂来形成压制产品。在这种情况下，平均粒度可以在约20-600微米的范围内。类似地，压实产品可以是使用一定量的饱和的，通常为固体的脂肪酰胺作为粘合剂，由平均粒度至少为175微米的1,3-二溴-5,5-二甲基乙内酰脲形成的产品。

62. 发明授权

US06551607B1 Method for sequestration of skin irritants with substrate compositions 失效
标题翻译：用底物组合物螯合皮肤刺激物的方法
公开(公告)号：US06551607B1
公开(公告)日：2003-04-22
申请号：US09474490
申请日：1999-12-29
申请人： Bernard Joseph Minerath, III , David Roland Otts , Linda Susan Huard , David John Tyrrell , Robert Cosmo DiLuccio , Frank Jerrel Akin , Chantel Spring Buhrow , Dennis Stein Everhart , Brenda Marie Nelson , Gary Lee Shanklin
发明人： Bernard Joseph Minerath, III , David Roland Otts , Linda Susan Huard , David John Tyrrell , Robert Cosmo DiLuccio , Frank Jerrel Akin , Chantel Spring Buhrow , Dennis Stein Everhart , Brenda Marie Nelson , Gary Lee Shanklin
IPC分类号： A01N2534
CPC分类号： A61K8/19 , A61K8/02 , A61K8/0208 , A61K8/25 , A61K8/26 , A61K8/29 , A61K2800/75 , A61L15/18 , A61L15/34 , A61L15/46 , A61L2300/22 , A61L2300/412 , A61Q19/00 , A61Q19/10
摘要： The present invention relates to a method of sequestering skin irritants with a skin irritant sequestering composition comprising a substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. The present invention further also provides a method of sequestering skin irritants comprising administering to the stratum corneum of an individual's skin a skin irritant sequestering composition comprising a substrate, a skin irritant sequestering amount of a combination of hydrophilic and hydrophobic skin irritant sequestering agents. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.
摘要翻译：本发明涉及一种用皮肤刺激性螯合组合物螯合皮肤刺激物的方法，其包含底物，亲水性皮肤刺激性螯合剂和疏水性皮肤刺激性螯合剂。在一个实施方案中，螯合剂由改性和未改性的粘土组成。本发明还提供了一种螯合皮肤刺激剂的方法，包括对个体皮肤的角质层施用皮肤刺激性螯合组合物，其包含底物，皮肤刺激物螯合量的亲水和疏水性皮肤刺激性螯合剂的组合。在一个实施方案中，皮肤刺激物与存在于底物上的螯合剂结合。在另一个实施方案中，皮肤刺激物与存在于皮肤上的螯合剂结合。

63. 发明授权

US06531145B1 Animal attractant, repellant and training scent product and method 失效
标题翻译：动物引诱剂，驱虫剂和培养香精产品及方法
公开(公告)号：US06531145B1
公开(公告)日：2003-03-11
申请号：US09607050
申请日：2000-06-30
申请人： Tony J. Reichert
发明人： Tony J. Reichert
IPC分类号： A01N2534
CPC分类号： A01N25/18 , A01N25/34 , Y10S119/905
摘要： A method for luring animals, repelling animals and training animals and a product used therewith comprising microporous beads having animal attractant scents, animal repellant scents and animal training scents, respectively, imbibed within the beads. The beads with the animal attractant scents are configured to release the animal attractant scents in order to attract a predetermined animal. Likewise, the beads with the animal repellant scents are configured to release the animal repellant scents in order to repel a predetermined animal. Similarly, the beads with the animal training scents are placed onto a predetermined location and a predetermined animal is trained to perform a predetermined sequence using the beads.
摘要翻译：用于诱导动物，排斥动物和训练动物的方法以及使用的产品，其中分别包含具有动物引诱剂气味的微孔珠粒，动物驱避香料和动物培养香料，其吸收在珠粒内。具有动物引诱剂气味的珠被配置为释放动物引诱剂气味以吸引预定的动物。同样地，具有动物驱避香味的珠被构造成释放动物驱避剂气味以排斥预定的动物。类似地，将具有动物训练香气的珠子放置在预定位置上，并训练预定动物以使用珠子执行预定序列。

64. 发明授权

US06521243B2 Ionic chitosan -iodine complexes: antiseptic hydrogels and wound healing promoters 有权
标题翻译：离子壳聚糖 - 碘复合物：消毒水凝胶和伤口愈合促进剂
公开(公告)号：US06521243B2
公开(公告)日：2003-02-18
申请号：US09748335
申请日：2000-12-22
申请人： EmadEldin M. Hassan
发明人： EmadEldin M. Hassan
IPC分类号： A01N2534
CPC分类号： A61K33/18 , A61K47/61 , A61K31/715 , A61K2300/00
摘要： This invention describes non-staining, pharmaceutically useful compositions of ionic complexes made between the cationic polymer chitosan or its derivatives and the small anionic iodine-iodide complex (ICIC's). Unlike previously disclosed ion transfer chitosan iodine complexes, ICIC's were found to possess dramatically higher viscosity than those of each ingredient separately, and instantly form a gel structure that is easily dispersible upon shaking. In addition to their antiseptic power, ICIC's showed better skin biocompatibility than povidone iodine and effectively promoted wound healing.
摘要翻译：本发明描述了在阳离子聚合物壳聚糖或其衍生物和小型阴离子碘碘化物络合物（ICIC's）之间制备的离子络合物的非染色，药学上有用的组合物。与以前公开的离子转移壳聚糖碘络合物不同，发现ICIC具有比每种成分分别高得多的粘度，并立即形成在振动时容易分散的凝胶结构。除了防腐功能外，ICIC显示出比聚维酮碘更好的皮肤生物相容性，有效促进伤口愈合。

65. 发明授权

US06514511B1 Composition, method, and apparatus to attract bees 失效
标题翻译：用于吸引蜜蜂的组成，方法和装置
公开(公告)号：US06514511B1
公开(公告)日：2003-02-04
申请号：US09568310
申请日：2000-05-08
申请人： Steven C. Thoenes
发明人： Steven C. Thoenes
IPC分类号： A01N2534
CPC分类号： A01N37/40 , A01K57/00 , A01N37/02 , A01N37/36 , A01N37/42 , A01N49/00 , A01N31/02 , A01N31/16 , A01N2300/00
摘要： Applicant's invention includes an improved bee attracting composition. Applicant's invention further includes a bee attracting device formed from his improved bee attracting composition. Applicant's bee attracting device can be further coated with a second bee attracting composition. Applicant's invention further includes a method and apparatus for attracting and immobilizing bees using a substrate coated with an adhesive composition upon which Applicant's bee attracting composition is disposed.
摘要翻译：申请人的发明包括改进的蜜蜂吸引组合物。申请人的发明还包括由他改进的蜂吸引组合物形成的蜜蜂吸引装置。申请人的蜜蜂吸引装置可以进一步涂覆第二种蜂吸引组合物。申请人的发明还包括使用涂布有申请人的蜂吸引组合物的粘合剂组合物的基材来吸引和固定蜜蜂的方法和装置。

66. 发明授权

US06488998B1 Pipe wrap for preventing microbiologically influenced corrosion in buried conduits 有权
标题翻译：用于防止隐蔽管道中微生物影响的腐蚀管道
公开(公告)号：US06488998B1
公开(公告)日：2002-12-03
申请号：US09630195
申请日：2000-08-01
申请人： John A. Crook
发明人： John A. Crook
IPC分类号： A01N2534
CPC分类号： F16L58/109 , A01N25/34 , F16L58/1054 , Y10T428/1393 , Y10T428/31692 , Y10T428/31909 , Y10T428/31913 , Y10T428/31938
摘要： An improved anti-corrosive material used to protect buried conduits from corrosion. The anti-corrosive material is comprised of a conduit contacting layer of polyolefin having the anti-corrosive agents impregnated therein. The preferred embodiment of the material is a multi-layered co-extruded, calendered, or laminated polyolefin. The material has an outer layer, or environment contacting layer, preferably comprised of a low density polyethylene having characteristically strong tensile strength and elongation properties to provide conventional protection from soil, water, air, or other potentially damaging elements. The material has a center layer preferably comprised of a high density polyethylene having superior tensile strength to provide a high density barrier between the outer layer and an inner layer. The inner layer, or conduit contacting layer, is preferably comprised of a low density polyethylene impregnated with one or more antimicrobial additives. The antimicrobial additives are incorporated into and dispersed throughout the conduit contacting layer for killing corrosion-inducing bacteria on the surface of the conduit. The antimicrobial additives are able to migrate through the low density polymer matrix but the rate of migration of the biocide is considerably slowed through the high density polymer. Thus, the antimicrobial agents are substantially prevented from escaping into the surrounding environment, but rather, are trapped within a “protection zone” immediately adjacent the conduit surface to provide extended protection against corrosion.
摘要翻译：一种改进的防腐蚀材料，用于保护埋地管道免受腐蚀。防腐蚀材料由聚烯烃的导管接触层组成，其中浸渍有抗腐蚀剂。材料的优选实施方案是多层共挤出，压延或层压的聚烯烃。该材料具有外层或环境接触层，优选由低密度聚乙烯组成，具有特征强的拉伸强度和伸长性能，以提供常规的保护免受土壤，水，空气或其它可能有害的元素。该材料具有优选由具有优异的拉伸强度的高密度聚乙烯组成的中心层，以在外层和内层之间提供高密度的屏障。内层或导管接触层优选由浸渍有一种或多种抗微生物添加剂的低密度聚乙烯组成。抗微生物添加剂并入并分散在整个导管接触层中，用于在管道表面上杀死腐蚀性细菌。抗微生物添加剂能够通过低密度聚合物基质迁移，但通过高密度聚合物，杀生物剂的迁移速率显着降低。因此，基本上防止了抗微生物剂逃逸到周围环境中，而是被捕获在紧邻导管表面的“保护区”内，以提供延长的防腐蚀保护。

67. 发明授权

US06461628B1 Non-woven keratin cell scaffold 有权
标题翻译：无纺布角蛋白细胞支架
公开(公告)号：US06461628B1
公开(公告)日：2002-10-08
申请号：US09587157
申请日：2000-06-05
申请人： Cheryl R. Blanchard , Mark E. Van Dyke , Scott F. Timmons , Arlene J. Siller-Jackson , Robert A. Smith
发明人： Cheryl R. Blanchard , Mark E. Van Dyke , Scott F. Timmons , Arlene J. Siller-Jackson , Robert A. Smith
IPC分类号： A01N2534
CPC分类号： A61K8/042 , A61F2013/530481 , A61F2013/530613 , A61K8/65 , A61K9/146 , A61K9/2063 , A61K9/7007 , A61K38/17 , A61K47/42 , A61K47/6953 , A61L15/32 , A61L27/227 , A61Q19/00
摘要： A hydratable, highly absorbent keratin solid fiber or powder capable of absorbing a large weight excess of water may be produced by partially oxidizing hair keratin disulfide bonds to sulfonic acid residues and reacting the sulfonic acid residues with a cation. The neutralized suspension can be filtered, washed, and dried, leaving keratin solid which can be shredded into fibers and further ground into powder. Addition of water to the solid produces a hydrogel. The powder or hydrogel may be useful as an absorbent material, as a therapeutic for skin, or as an excipient. The keratin materials can be incorporated into nonwoven films. The hydrogel may be used as biocompatible viscoelastic filler for implant applications. Both the hydrogel and nonwoven materials are also suitable for use as tissue engineering scaffolds.
摘要翻译：可以通过将毛发角蛋白二硫键部分氧化成磺酸残基并使磺酸残基与阳离子反应来制备能够吸收大量过量水的可水合的高吸收性角蛋白固体纤维或粉末。中和的悬浮液可以过滤，洗涤和干燥，留下角蛋白固体，将其切成纤维并进一步研磨成粉末。向固体中加入水产生水凝胶。粉末或水凝胶可用作吸收材料，作为皮肤的治疗剂或赋形剂。角蛋白材料可以并入无纺膜中。水凝胶可用作植入物应用的生物相容性粘弹性填料。水凝胶和非织造材料都适用于组织工程支架。

68. 发明授权

US06444215B1 Plaster for removing comedones from the skin 失效
标题翻译：从皮肤上去除粉刺的石膏
公开(公告)号：US06444215B1
公开(公告)日：2002-09-03
申请号：US09600873
申请日：2000-08-11
申请人： Fausto Pinna , Marco Pinna
发明人： Fausto Pinna , Marco Pinna
IPC分类号： A01N2534
CPC分类号： A61K8/732 , A61K8/0208 , A61K8/64 , A61Q19/00
摘要： Plaster at least partially covered with a layer of dextrin and/or casein and/or starch having an amylopectin content of at least 80%, which when moistened is made to adhere to the skin on which comedones are present, these being removed when the plaster is itself removed after the layer has dried.
摘要翻译：至少部分地覆盖有糊精和/或酪蛋白和/或支链淀粉含量至少为80％的淀粉，其当被润湿时粘附到存在麦克风的皮肤上，当石膏在层被干燥之后本身被去除。

69. 发明授权

US06410039B1 Protective topical composition, products including the same, and methods 失效
标题翻译：保护性局部组合物，产品包括相同的方法和方法
公开(公告)号：US06410039B1
公开(公告)日：2002-06-25
申请号：US09396580
申请日：1999-09-15
申请人： Edward B. Walker
发明人： Edward B. Walker
IPC分类号： A01N2534
CPC分类号： A61Q19/00 , A61K8/0208 , A61K8/06 , A61K8/062 , A61K8/39 , A61K8/86 , A61K8/891 , A61K9/107 , A61K2800/524 , A61Q17/005 , A61Q19/10 , Y10S514/844 , Y10S514/938
摘要： A topical composition with silicone oil emulsified in water. The topical composition may be made by diluting a concentrated silicone oil-in-water emulsion with water. The silicone oil of the topical composition and of the concentrated silicone oil-in-water emulsion is suspended in the water by one or more non-ionic surfactants. A combination of non-ionic surfactants may be employed. The topical composition may also include a blend of preservatives, which may be selected to have a synergistic effect. The silicone oil constitutes about 35% of the weight of the concentrated silicone oil-in-water emulsion. The non-ionic surfactant or surfactants make up about 3.5% of the weight of the concentrated oil-in-water emulsion. The diluted topical composition may contain silicone oil in amounts of about 0.1 to about 35%, preferably less than 3% down to about 1%, and more preferably about 1 to about 2% of the weight of the topical composition. The invention also includes wipe sheets wetted or impregnated with the topical composition. The topical composition can be applied to skin by way of a wet wipe, by spraying, or by rubbing into the skin.
摘要翻译：含有硅油的局部组合物在水中乳化。局部组合物可以通过用水稀释浓缩的硅氧烷水包油乳液来制备。局部组合物的硅油和浓缩的硅氧烷水包油乳液通过一种或多种非离子表面活性剂悬浮在水中。可以使用非离子表面活性剂的组合。局部组合物还可以包括防腐剂的混合物，其可以选择具有协同效应。硅油占浓缩硅油水包油乳液重量的约35％。非离子表面活性剂或表面活性剂占浓缩水包油乳液重量的约3.5％。稀释的局部组合物可以含有局部组合物重量的约0.1至约35％，优选小于3％至约1％，更优选约1至约2％的硅油。本发明还包括用局部组合物湿润或浸渍的擦拭片。局部组合物可以通过湿擦拭，喷雾，或通过摩擦皮肤施用于皮肤。

70. 发明授权

US06383508B1 Animal repellent and method 有权
标题翻译：动物驱避剂和方法
公开(公告)号：US06383508B1
公开(公告)日：2002-05-07
申请号：US09783625
申请日：2001-02-14
申请人： James Messina
发明人： James Messina
IPC分类号： A01N2534
CPC分类号： A01N65/00 , A01N25/04 , A01N25/34 , A01N65/22 , Y10S514/92 , A01N37/02 , A01N63/02
摘要： A deer and geese repellent formulation and method for warding off geese or deer from a shrub or plant. The formulation is an admixture of water, Rosemary oil emulsion, mint oil emulsion, a thickener, white distilled vinegar and dried eggs. The formulation can be applied to a support medium, such as clay or a length of rope, and then associated with the vegetation to be protected. The formulation can also be formed into a viscous composition and used in containers near the vegetation to be protected.
摘要翻译：用于从灌木或植物中防止鹅或鹿的鹿和鹅驱避剂制剂和方法。制剂是水，迷迭香油乳液，薄荷油乳液，增稠剂，白色蒸馏醋和干蛋的混合物。制剂可以应用于支撑介质，例如粘土或长度的绳索，然后与待保护的植被相关联。制剂也可以形成粘稠组合物，并用于待保护的植被附近的容器中。

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