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61. 发明申请

US20120264163A1 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING 有权
标题翻译：检测细菌生长发育的装置和方法
公开(公告)号：US20120264163A1
公开(公告)日：2012-10-18
申请号：US13426507
申请日：2012-03-21
申请人： Jon Booher
发明人： Jon Booher
IPC分类号： C12Q1/04
CPC分类号： A61F15/00 , A61B5/14539 , A61B5/412 , A61B5/445 , A61F13/00059 , A61F13/00063 , A61F13/022 , A61F2013/00153 , A61F2013/00182 , A61F2013/00412 , A61F2013/00429 , A61F2013/00434 , A61F2013/00604 , A61F2013/00846 , A61F2013/00851 , A61F2013/00948 , A61F2013/00965 , A61F2013/8473 , A61F2013/8497 , A61L15/42 , A61L29/14
摘要： An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a wound dressing, in one example used to cover an indwelling central venous catheter or other catheter. A bacteria detection apparatus includes a barrier membrane, a permeable membrane for placement proximate a wound or a catheter insertion site, and an indicator between the barrier membrane and the permeable membrane for indicating the presence of bacteria proximate the permeable membrane. A method of using a bacterial growth detection apparatus is also provided.
摘要翻译：提供了一种设备和方法，用于在用于覆盖中心静脉导管或其它的一个实例中的视觉监测，检测和/或确定伤口敷料下方的有害或潜在有害细菌微生物的存在，不存在和/或生长导管。细菌检测装置包括阻挡膜，用于放置在伤口附近的可渗透膜或导管插入位置，以及阻挡膜和可渗透膜之间的指示剂，用于指示靠近渗透膜的细菌的存在。还提供了使用细菌生长检测装置的方法。

62. 发明授权

US08197844B2 Active electrode for transdermal medicament administration 有权
标题翻译：用于透皮药物给药的活性电极
公开(公告)号：US08197844B2
公开(公告)日：2012-06-12
申请号：US11811241
申请日：2007-06-08
申请人： Jamal S. Yanaki
发明人： Jamal S. Yanaki
IPC分类号： A61F13/00 , A61F13/02 , A61B5/04
CPC分类号： A61N1/30 , A61F13/00051 , A61F13/02 , A61F2013/00285 , A61F2013/00417 , A61F2013/00442 , A61F2013/00489 , A61F2013/00646 , A61F2013/00906 , A61F2013/00919 , A61F2013/00948 , A61F2013/00961
摘要： A transdermal medicament patch includes a biocompatible substrate having a therapeutic face on one side configured for disposition against the skin of a patient, a biocompatible adhesive on the therapeutic face, a planar medicament matrix covering a portion of the therapeutic face, and a release liner covering the portion of therapeutic that is not obscured by the medicament matrix. An aperture formed through the release sheet affords direct access by medicament to the entire surface of the medicament matrix opposite from the therapeutic face of the substrate. An active electrode positioned between the medicament matrix and the therapeutic face of the substrate includes an electrically conductive backing layer positioned against the therapeutic face of the substrate and a pH-control layer covering less than all of the side of the backing layer opposite from the therapeutic face of the substrate. One active electrode design criterion relates the relative size of the pH-control layer to the size of the backing layer; another relates the size of portion of the area of the backing layer that is free of the pH-control lawyer to the size of the pH-control layer. The pH-control layer is made of an electrically conductive material capable of moderating changes in the hydrogen-ion concentration in the medicament matrix during iontophoretic current flow. An electrical contact electrically coupled through the substrate to the backing layer includes a hollow, electrically conductive snap fitting having an open end and a cooperating stud that is inserted into the open end of the snap.
摘要翻译：透皮药物贴片包括生物相容性基底，其具有在一侧上的治疗面，其配置用于处置患者的皮肤，治疗面上的生物相容性粘合剂，覆盖治疗面部分的平面药物基质和释放衬垫覆盖物不被药物基质遮蔽的治疗部分。通过剥离片形成的孔可以通过药物直接进入与基底的治疗面相反的药物基质的整个表面。位于药物基质和基底的治疗面之间的有源电极包括抵靠基底的治疗面定位的导电背衬层和覆盖与治疗组相反的背衬层全部侧面的pH控制层基材面。一个活性电极设计标准将pH控制层的相对尺寸与背衬层的尺寸相关; 另一个涉及不含pH控制律师的背衬层的面积的部分尺寸与pH值控制层的尺寸。 pH控制层由能够调节离子电渗电流期间药物基质中氢离子浓度变化的导电材料制成。通过基底电耦合到背衬层的电触点包括具有开口端的中空的导电卡扣配件，以及插入卡扣的开口端的协作钉。

63. 发明授权

US07112713B2 Dressing based on the Teorell-Meyer gradient 有权
标题翻译：基于Teorell-Meyer渐变的敷料
公开(公告)号：US07112713B2
公开(公告)日：2006-09-26
申请号：US10832994
申请日：2004-04-28
申请人： Nicholas A Sceusa
发明人： Nicholas A Sceusa
IPC分类号： A61F13/00
CPC分类号： A61F13/00063 , A61F2013/00157 , A61F2013/0017 , A61F2013/00472 , A61F2013/00519 , A61F2013/00927 , A61F2013/00948
摘要： A dressing designed in consideration of Teorell-Meyer gradients is described. This dressing delivers, either individually, or seriatim, pharmaceutically effective amounts of drugs and therapeutic ions to a wound site.
摘要翻译：描述了考虑到Teorell-Meyer梯度设计的敷料。这种敷料可单独地或连续地向伤口部位提供药学上有效量的药物和治疗离子。

64. 发明授权

US6051249A Dressing having a three-dimensional part and processes for the preparation of such a dressing 失效
标题翻译：具有三维部分的敷料和用于制备这种敷料的方法
公开(公告)号：US6051249A
公开(公告)日：2000-04-18
申请号：US875421
申请日：1997-07-28
申请人： Peter Boman Samuelsen
发明人： Peter Boman Samuelsen
IPC分类号： A61F13/00 , A61F13/02 , A61F13/06 , A61F13/10
CPC分类号： A61F13/105 , A61F13/0276 , A61F13/067 , A61F13/068 , A61F13/101 , A61F2013/00119 , A61F2013/00229 , A61F2013/00395 , A61F2013/00574 , A61F2013/00629 , A61F2013/00676 , A61F2013/00748 , A61F2013/00757 , A61F2013/00761 , A61F2013/0091 , A61F2013/00927 , A61F2013/00948 , A61F2013/0097 , Y10S602/901
摘要： A dressing comprising a body facing layer of a thermoplastic adhesive and a carrier film and an absorbent material, the dressing having in itself an outwardly facing convex surface and an inwardly facing concave surface, wherein the dressing comprises a first area facing the wound or skin, the area having essentially three-dimensional geometry and optionally a second area, the first area preferably comprising a hydrocolloid adhesive and a carrier film, and the second area essentially showing adhesive properties and preferably comprising a carrier film and a hydrocolloid adhesive and wherein the adhesive in one or both areas is optionally covered by one or more layers to be removed before use.
摘要翻译： PCT No.PCT / DK96 / 00043 Sec。 371日期1997年7月28日第 102（e）日期1997年7月28日PCT 1996年1月26日PCT PCT。第WO96 / 22754号公报日期1996年8月1日一种包含热塑性粘合剂的面向身体的层和载体膜和吸收材料的敷料，所述敷料本身具有向外的凸形表面和向内的凹面，其中所述敷料包括面向所述伤口或皮肤，所述区域具有基本上三维的几何形状和任选的第二区域，所述第一区域优选地包括水胶体粘合剂和载体膜，并且所述第二区域基本上显示粘合性质，并且优选地包含载体膜和水胶体粘合剂并且其中一个或两个区域中的粘合剂任选地被一个或多个层覆盖，以在使用前除去。

65. 发明授权

US5181905A Method of monitoring the condition of the skin or wound 失效
标题翻译：监测皮肤或伤口状况的方法
公开(公告)号：US5181905A
公开(公告)日：1993-01-26
申请号：US759129
申请日：1991-09-10
申请人： Eric Flam
发明人： Eric Flam
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61L15/56 , A61L15/58
CPC分类号： A61L15/56 , A61F13/00051 , A61F13/0213 , A61F13/0246 , A61L15/585 , A61F2013/00387 , A61F2013/00757 , A61F2013/0094 , A61F2013/00944 , A61F2013/00948 , A61F2013/00953 , A61F2013/00957 , A61F2013/00961 , A61F2013/00965 , A61F2013/15024
摘要： A dressing having a skin or wound contacting surface is provided with an indicator means on the opposite surface. The indicator means is capable of sensing the condition of the skin or wound underlying the dressing and conveying the information to the health care professional eliminating the need to frequently change the dressing.
摘要翻译：具有皮肤或伤口接触表面的敷料在相对表面上设置有指示装置。指示装置能够感测敷料下面的皮肤或伤口的状况，并将信息传达给保健专业人员，消除了经常改变敷料的需要。

66. 发明申请

WO2008153931A3 TRANSDERMAL MEDICAMENT PATCH AND ACTIVE ELECTRODE FOR SAME 审中-公开
标题翻译：用于同种异体的药物传递物质和活性电极
公开(公告)号：WO2008153931A3
公开(公告)日：2009-03-12
申请号：PCT/US2008007109
申请日：2008-06-06
申请人： ACTIVATEK INC , YANAKI JAMAL S
发明人： YANAKI JAMAL S
IPC分类号： A61N1/30
CPC分类号： A61N1/30 , A61F13/00051 , A61F13/02 , A61F2013/00285 , A61F2013/00417 , A61F2013/00442 , A61F2013/00489 , A61F2013/00646 , A61F2013/00906 , A61F2013/00919 , A61F2013/00948 , A61F2013/00961
摘要： A transdermal medicament patch (18,0168) includes a substrate(32, 172) having a therapeutic face (40, 180) configured for disposition against the skin (102), an adhesive on the therapeutic face (40, 180), a planar medicament matrix (46, 188) covering a portion of the therapeutic face (46,188), and a release liner (41, 182) covering the portion of therapeutic face (40, 180) not obscured by the medicament matrix (46, 188) An aperture (44, 186) through the release liner (41, 182) affords access to the medicament matnx (46, 188) An active electrode (54, 110, 120, 130, 140, 150, 210, 230, 250,270, 290) positioned between the medicament matrix (46,188) and the therapeutic face (40, 180) includes an electpcally conductive backing layer (56, 142, 152,212,232,252,272, 292) positioned against the therapeutic face (40, 180) and a pH-control layer (58, 132, 146, 156,216, 236, 256, 276, 296) that moderates changes in hydrogen-ion concentration covering
摘要翻译：透皮药物贴剂（18,0168）包括具有配置用于处置皮肤（102）的治疗面（40,180）的基底（32,172），治疗面（40,180）上的粘合剂，平面覆盖治疗面（46,188）的一部分的药物基质（46,188）和覆盖治疗面（40,180）部分的释放衬垫（41,182），其不被药物基质（46,188）遮蔽。通过释放衬垫（41,182）的孔径（44,186）可以进入药物基质（46,188）。有效电极（54,110,120,130,140,150,210,230,250,270,290）位于药物基质（46,188）和治疗面（40,180）之间的电极包括位于治疗面（40,180）和pH控制层（58）上的电导电背衬层（56,142,152,212,232,252,272,292），132,146,156,216,236,256,276,296），其缓和了氢离子浓度的变化

67. 发明申请

WO2008153931A2 TRANSDERMAL MEDICAMENT PATCH AND ACTIVE ELECTRODE FOR SAME 审中-公开
标题翻译：用于同种异体的药物传递物质和活性电极
公开(公告)号：WO2008153931A2
公开(公告)日：2008-12-18
申请号：PCT/US2008/007109
申请日：2008-06-06
申请人： ACTIVATEK, INC. , YANAKI, Jamal, S.
发明人： YANAKI, Jamal, S.
IPC分类号： A61B5/04 , A61F13/00 , A61F13/02
CPC分类号： A61N1/30 , A61F13/00051 , A61F13/02 , A61F2013/00285 , A61F2013/00417 , A61F2013/00442 , A61F2013/00489 , A61F2013/00646 , A61F2013/00906 , A61F2013/00919 , A61F2013/00948 , A61F2013/00961
摘要： A transdermal medicament patch ( 18,0168) includes a substrate(32, 172) having a therapeutic face (40, 180) configured for disposition against the skin (102), an adhesive on the therapeutic face (40, 180), a planar medicament matrix (46, 188) covering a portion of the therapeutic face (46,188), and a release liner (41, 182) covering the portion of therapeutic face (40, 180) not obscured by the medicament matrix (46, 188). An aperture (44, 186) through the release liner (41, 182) affords access to the medicament matrix (46, 188). An active electrode (54, 110, 120, 130, 140, 150, 210, 230, 250, 270, 290) positioned between the medicament matrix (46, 188) and the therapeutic face (40, 180) includes an electrically conductive backing layer (56, 142, 152, 212, 232, 252, 272, 292) positioned against the therapeutic face (40, 180) and a pH-control layer (58, 132, 146, 156, 216, 236, 256, 276, 296) that moderates changes in hydrogen-ion concentration covering less than all of the therapeutic face (40, 180). One active electrode design criterion relates the size of the pH-control layer to the size of the backing layer; another relates the size of the portion of the backing layer not covered by the pH-control layer to the size of the pH-control layer.
摘要翻译：透皮药物贴剂（18,0168）包括具有配置用于处置皮肤（102）的治疗面（40,180）的基底（32,172），治疗面（40,180）上的粘合剂，平面覆盖治疗面（46,188）的一部分的药物基质（46,188）和覆盖治疗面部（40,180）的部分而不被药物基质（46,188）遮蔽的释放衬垫（41,182）。穿过释放衬垫（41,182）的孔（44,186）可以进入药物基质（46,188）。位于药物基质（46,188）和治疗面（40,180）之间的有源电极（54,110,120,130,140,150,210,230,250,270,290）包括导电背衬定位在治疗面（40,180）和pH控制层（58,132,146,156,216,236,256,276）之间的层（56,142,152,212,232,252,272,292），296），其缓和氢离子浓度的变化，其覆盖率小于所有治疗面（40,180）。一个活性电极设计标准将pH控制层的尺寸与背衬层的尺寸相关联; 另一个涉及未被pH控制层覆盖的背衬层的部分的尺寸与pH值控制层的尺寸。

68. 发明申请

WO02047737A1 DRESSINGS FOR THE TREATMENT OF EXUDING WOUNDS 审中-公开
标题翻译：用于治疗排泄物的衣服
公开(公告)号：WO02047737A1
公开(公告)日：2002-06-20
申请号：PCT/GB2001/005466
申请日：2001-12-11
IPC分类号： A61F13/00 , A61L15/42
CPC分类号： A61F13/0203 , A61F13/00063 , A61F13/069 , A61F2013/00157 , A61F2013/00523 , A61F2013/00604 , A61F2013/0091 , A61F2013/00936 , A61F2013/00948 , A61L15/42
摘要： The invention provides a layered wound dressing material comprising: a wound facing hydrogel layer (9) and a barrier layer, wherein the barrier layer comprises a pH-sensitive material that is substantially insoluble in water at 25 DEG C under acidic conditions, but substantially soluble in water at 25 DEG C under neutral or alkaline conditions. In use, the hydrogel layer (9) absorbs and is gradually neutralized by wound exudate until its pH rises to a level that causes dissolution of the barrier layer, thereby allowing excess exudate to flow out from the hydrogen layer. The invention further provides wound dressings comprising such barrier layers and methods of use of such dressings.
摘要翻译：本发明提供了一种分层伤口敷料材料，其包括：面向卷绕的水凝胶层（9）和阻挡层，其中所述阻挡层包含在25℃下在酸性条件下基本上不溶于水的pH敏感材料，但基本上可溶在25℃的中性或碱性条件下进行。在使用中，水凝胶层（9）吸收并被伤口渗出液逐渐中和，直到其pH升高到导致阻挡层溶解的水平，从而允许过量的渗出物从氢层流出。本发明进一步提供包含这种屏障层的伤口敷料以及使用这种敷料的方法。

69. 发明申请

WO00061046A1 A PRESSURE RELIEVING DRESSING 审中-公开
标题翻译：压力消除接头
公开(公告)号：WO00061046A1
公开(公告)日：2000-10-19
申请号：PCT/DK2000/000168
申请日：2000-04-06
IPC分类号： A61F13/02
CPC分类号： A61F13/0203 , A61F13/0263 , A61F13/069 , A61F2013/00272 , A61F2013/00387 , A61F2013/0074 , A61F2013/00748 , A61F2013/0091 , A61F2013/00948 , A61F2013/00957 , A61F2013/530562
摘要： A pressure relieving dressing comprising an absorbing element and a substantially non-absorbing pressure distributing element, in which the absorbent element constitutes a part of a proximal skin contacting surface, said absorbing element being encircled by the pressure distributing element or being situated at the border of the pressure distributing element constituting the remaining part of the surface of the dressing to be in contact with the skin rendering it possible to obtain an effective and durable dressing suitable for both wound healing and prophylaxis of pressure ulcers.
摘要翻译：一种减压敷料，包括吸收元件和基本上不吸收的压力分布元件，其中吸收元件构成近端皮肤接触表面的一部分，所述吸收元件被压力分布元件包围或位于构成敷料表面剩余部分的压力分布元件与皮肤接触，使得可以获得适合伤口愈合和预防压疮的有效耐久的敷料。

70. 发明公开

EP1893147A4 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING 无效
标题翻译：设备和检测方法的细菌的生长的下伤口敷料
公开(公告)号：EP1893147A4
公开(公告)日：2011-04-06
申请号：EP06772784
申请日：2006-06-08
申请人： INDICATOR SYSTEMS INTERNATIONAL INC
发明人： BOOHER JON
IPC分类号： A61F13/02
CPC分类号： A61F15/00 , A61B5/14539 , A61B5/412 , A61B5/445 , A61F13/00059 , A61F13/00063 , A61F13/022 , A61F2013/00153 , A61F2013/00182 , A61F2013/00412 , A61F2013/00429 , A61F2013/00434 , A61F2013/00604 , A61F2013/00846 , A61F2013/00851 , A61F2013/00948 , A61F2013/00965 , A61F2013/8473 , A61F2013/8497 , A61L15/42 , A61L29/14

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