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61. 发明授权

US08498463B2 Mask construction for cardiac subtraction 有权
标题翻译：心脏减量的面罩构造
公开(公告)号：US08498463B2
公开(公告)日：2013-07-30
申请号：US13058205
申请日：2009-08-06
申请人： Raoul Florent , Vincent Maurice Andre Auvray , Odile Bonnefous
发明人： Raoul Florent , Vincent Maurice Andre Auvray , Odile Bonnefous
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/484 , A61B6/507 , A61B6/5264
摘要： To provide an improved method for achieving DSA images where the effect of residual motions in cardiac DSA during the perfusion phase is reduced and in order to display subtracted images containing less motion artefacts, a method of performing digital subtraction angiography DSA in an imaging apparatus comprises the steps of generating a first image sequence of mask images (10) of a subject to be examined, generating at least one first contrast image (22) at a first phase (16) whereby in the first contrast image part of the subject has a different contrast than in said first image sequence, subtracting the mask images (10) from the at least one first contrast image (22) generating a first DSA image sequence (24), subtracting the DSA images of the first DSA image sequence (24) from the first contrast image (22) within the first phase (16) generating a sequence of extended mask images (32); generating a second contrast image (34) with the imaging system at a second phase (18), said second phase (18) being separated from the first phase (16) by a predetermined phase dividing time limit (20), subtracting the images of the sequence of the extended mask images (32) from the second contrast image (34) generating a second DSA image sequence (38), displaying the second DSA image sequence (38) on a display (28).
摘要翻译：为了提供一种用于实现DSA图像的改进方法，其中在灌注阶段期间心脏DSA中的残留运动的影响减小，并且为了显示包含较少运动伪影的减影图像，在成像设备中执行数字减影血管造影DSA的方法包括产生待检查对象的掩模图像（10）的第一图像序列的步骤，在第一阶段（16）产生至少一个第一对比图像（22），由此在对象的第一对比图像部分中具有不同的与所述第一图像序列相比，从产生第一DSA图像序列（24）的至少一个第一对比图像（22）中减去掩模图像（10），从第一DSA图像序列（24）的DSA图像中减去第一DSA图像序列第一相位（16）内的第一对比度图像（22）产生延伸的掩模图像序列（32）; 在第二阶段（18）产生具有成像系统的第二对比度图像（34），所述第二相位（18）与预定的相位分割时间限制（20）从第一相位（16）分离，减去图像来自第二对比度图像（34）的扩展掩模图像（32）的序列生成第二DSA图像序列（38），在显示器（28）上显示第二DSA图像序列（38）。

62. 发明申请

US20130116551A1 3D-ORIGINATED CARDIAC ROADMAPPING 有权
标题翻译： 3D原版CARDIAC ROADMAPPING
公开(公告)号：US20130116551A1
公开(公告)日：2013-05-09
申请号：US13810292
申请日：2011-07-15
申请人： Raoul Florent , Vincent Auvray , Michael Grass , Dirk Schaefer , Gert Schoonenberg
发明人： Raoul Florent , Vincent Auvray , Michael Grass , Dirk Schaefer , Gert Schoonenberg
IPC分类号： A61B6/02
CPC分类号： A61B6/022 , A61B6/12 , A61B6/4441 , A61B6/463 , A61B6/487 , A61B6/504 , A61B6/5223 , A61B6/5235 , A61B2090/364 , A61B2090/367
摘要： The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.
摘要翻译：本发明涉及3D起源的心脏路线图。为了提高作为导航信息提供给用户的信息的准确性，对病人没有任何额外的负担，例如额外的X射线剂量，描述了一种方法，其包括以下步骤：a）提供一个物体的血管结构; b）获取所述对象的二维图像数据，所述对象包括所述血管结构，所述2D图像数据包括至少一个2D图像; c）投影血管结构，从而基于3D + t图像数据生成多个掩模图像; d）使用所述多个掩模图像之一登记所述至少一个2D图像，其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e）根据所述注册，基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f）将组合显示为引导血管树投影。因此，由于路线图基于三维数据，所以提供了形成路面图的形式的改进的心脏路线图。

63. 发明申请

US20130028384A1 AUTOMATIC POSITIONING OF ABSORPTION MEANS IN X-RAY IMAGE ACQUISITION 有权
标题翻译： X射线图像获取中吸收方式的自动定位
公开(公告)号：US20130028384A1
公开(公告)日：2013-01-31
申请号：US13636454
申请日：2010-03-31
申请人： Vincent Maurice Andre Auvray , Raoul Florent , Willem Frederik Den Hartog , Peter Willem Van Den Houten
发明人： Vincent Maurice Andre Auvray , Raoul Florent , Willem Frederik Den Hartog , Peter Willem Van Den Houten
IPC分类号： A61B6/00 , G06K9/20
CPC分类号： A61B6/481 , A61B6/032 , A61B6/06 , A61B6/4035 , A61B6/4441 , A61B6/488 , A61B6/504 , A61B6/5235 , A61B6/542 , A61B6/583
摘要： The present invention relates to automatic absorption means positioning in X-ray image acquisition. To improve image quality and to optimize the radiation exposure of an object, optimal position for X-ray absorption means is provided. A first sequence (113) of X-ray images is acquired (112). For each of the images, the optimal position (115) for X-ray absorption means is determined (114). A second sequence (117) of X-ray images is associated 10 (116) with corresponding images of the first sequence. The determined optimal position for the absorption means (14) of the associated corresponding images of the first sequence (113) is selected for an acquisition of the second sequence (117). Hence, a situation-specific database with optimized positions for the absorption means is generated on behalf of the first sequence in order to provide the generated position information for the actual acquisition of a 15 second sequence of images.
摘要翻译：本发明涉及在X射线图像采集中定位的自动吸收装置。为了提高图像质量并优化对象的辐射照射，提供了用于X射线吸收装置的最佳位置。获取X射线图像的第一序列（113）（112）。对于每个图像，确定用于X射线吸收装置的最佳位置（115）（114）。将X射线图像的第二序列（117）与第一序列的对应图像相关联（116）。选择第一序列（113）的相关对应图像的吸收装置（14）的确定的最佳位置用于获取第二序列（117）。因此，代表第一序列产生具有用于吸收装置的优化位置的状况特定的数据库，以便为实际获取15秒的图像序列提供所产生的位置信息。

64. 发明申请

US20120245458A1 COMBINATION OF ULTRASOUND AND X-RAY SYSTEMS 审中-公开
标题翻译：超声和X射线系统的组合
公开(公告)号：US20120245458A1
公开(公告)日：2012-09-27
申请号：US13513921
申请日：2010-11-30
申请人： Nicolas Pierre Bruno Gogin , Raoul Florent , Pascal Yves Francois Cathier
发明人： Nicolas Pierre Bruno Gogin , Raoul Florent , Pascal Yves Francois Cathier
IPC分类号： A61B8/12 , A61B6/03 , A61B6/00
CPC分类号： A61B8/00 , A61B6/00 , A61B6/12 , A61B6/503 , A61B6/5247 , A61B8/0883 , A61B8/4245 , A61B8/4416
摘要： The invention proposes to detect and track an intervention device in a 2D fluoroscopy image and to steer an ultrasound probe beam towards this device. Therefore, a method and corresponding system is proposed, by which an ultrasound probe is registered in a fluoroscopy image, wherein the registering includes the estimation of the position and of the orientation of the probe relative to the fluoroscopy.
摘要翻译：本发明提出在2D荧光透视图像中检测和跟踪介入装置，并将超声波探针束引向该装置。因此，提出了一种方法和相应的系统，通过该方法和相应的系统将超声波探头注册在荧光透视图像中，其中记录包括相对于荧光透视的位置和探针的取向的估计。

65. 发明申请

US20110305378A1 MASK CONSTRUCTION FOR CARDIAC SUBTRACTION 有权
标题翻译：用于心脏吸收的掩蔽结构
公开(公告)号：US20110305378A1
公开(公告)日：2011-12-15
申请号：US13058205
申请日：2009-08-06
申请人： Raoul Florent , Vincent Maurice Andre Auvray , Odile Bonnefous
发明人： Raoul Florent , Vincent Maurice Andre Auvray , Odile Bonnefous
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/484 , A61B6/507 , A61B6/5264
摘要： To provide an improved method for achieving DSA images where the effect of residual motions in cardiac DSA during the perfusion phase is reduced and in order to display subtracted images containing less motion artefacts, a method of performing digital subtraction angiography DSA in an imaging apparatus comprises the steps of generating a first image sequence of mask images (10) of a subject to be examined, generating at least one first contrast image (22) at a first phase (16) whereby in the first contrast image part of the subject has a different contrast than in said first image sequence, subtracting the mask images (10) from the at least one first contrast image (22) generating a first DSA image sequence (24), subtracting the DSA images of the first DSA image sequence (24) from the first contrast image (22) within the first phase (16) generating a sequence of extended mask images (32); generating a second contrast image (34) with the imaging system at a second phase (18), said second phase (18) being separated from the first phase (16) by a predetermined phase dividing time limit (20), subtracting the images of the sequence of the extended mask images (32) from the second contrast image (34) generating a second DSA image sequence (38), displaying the second DSA image sequence (38) on a display (28).
摘要翻译：为了提供一种用于实现DSA图像的改进方法，其中在灌注阶段期间心脏DSA中的残留运动的影响减小，并且为了显示包含较少运动伪影的减影图像，在成像设备中执行数字减影血管造影DSA的方法包括产生待检查对象的掩模图像（10）的第一图像序列的步骤，在第一阶段（16）产生至少一个第一对比图像（22），由此在对象的第一对比图像部分中具有不同的与所述第一图像序列相比，从产生第一DSA图像序列（24）的至少一个第一对比图像（22）中减去掩模图像（10），从第一DSA图像序列（24）的DSA图像中减去第一DSA图像序列第一相位（16）内的第一对比度图像（22）产生延伸的掩模图像序列（32）; 在第二阶段（18）产生具有成像系统的第二对比度图像（34），所述第二相位（18）与预定的相位分割时间限制（20）从第一相位（16）分离，减去图像来自第二对比度图像（34）的扩展掩模图像（32）的序列生成第二DSA图像序列（38），在显示器（28）上显示第二DSA图像序列（38）。

66. 发明申请

US20110135064A1 DYNAMICAL VISUALIZATION OF CORONARY VESSELS AND MYOCARDIAL PERFUSION INFORMATION 有权
标题翻译：冠状动脉和心肌灌注信息的动态可视化
公开(公告)号：US20110135064A1
公开(公告)日：2011-06-09
申请号：US13057772
申请日：2009-08-06
申请人： Antonius Johannes Cornelius Buijns , Peter Maria Johannes Rongen , Vincent Maurice Andre Auvray , Odile Bonnefous , Raoul Florent
发明人： Antonius Johannes Cornelius Buijns , Peter Maria Johannes Rongen , Vincent Maurice Andre Auvray , Odile Bonnefous , Raoul Florent
IPC分类号： H05G1/64
CPC分类号： A61B6/504 , A61B6/463 , A61B6/464 , A61B6/481 , A61B6/503 , A61B6/507 , A61B6/5217 , A61B6/5235 , A61B6/5264 , A61B6/541
摘要： A method for dynamically visualizing coronary information and an apparatus adapted to implement such method is described. In a preferred embodiment of the method, first dynamic cardiac data is acquired during a first cardiac stage and second dynamic cardiac data is acquired during a second cardiac stage. Then, the two data sets are visualized continuously the in a superimposed presentation, wherein the first cardiac data and the second cardiac data corresponding to a same phase within the cardiac cycle are visualized simultaneously. In this way for example information about the vessel geometry may be immediately linked with information about the muscle irrigation or perfusion. Furthermore, this useful information may be displayed in a high-contrasted and low-noise presentation.
摘要翻译：描述了用于动态可视化冠状动脉信息的方法和适于实现这种方法的装置。在该方法的优选实施例中，在第一心脏阶段期间获取第一动态心脏数据，并且在第二心脏阶段期间获取第二动态心脏数据。然后，以叠加的呈现连续显示两个数据集，其中与心脏周期内的相同相位相对应的第一心脏数据和第二心脏数据被同时显现。以这种方式，例如关于血管几何的信息可以立即与关于肌肉灌注或灌注的信息相关联。此外，该有用信息可以以高对比度和低噪声的呈现来显示。

67. 发明授权

US07738724B2 Image viewing system and method for generating filters for filtering image features according to their type 有权
标题翻译：图像查看系统和方法，用于根据其类型生成用于过滤图像特征的过滤器
公开(公告)号：US07738724B2
公开(公告)日：2010-06-15
申请号：US10544204
申请日：2004-02-03
申请人： Shérif Makram-Ebeid , Raoul Florent
发明人： Shérif Makram-Ebeid , Raoul Florent
IPC分类号： H04N5/14 , H04N9/64
CPC分类号： G06T5/20
摘要： Image processing system for generating a multidimensional adaptive oriented filter to be applied to the point intensities of a d-dimensional image, comprising analyzing means with means (5, fi) to estimate at each image point a probability measure (Fi) of the presence of a type of feature of interest and a weighting control model (10) issuing a weighting control vector (11, VC) constructed from said probability measure, for the user to control synthesized adaptive kernels at each image point; and synthesizing means for generating the filter kernels at each image point adapted to the type of the features of interest, whose filtering strength is controlled by the weighting control vector. The system may comprise a selection unit (40) for the user to select synthesizing means for generating “pre-mixing filtering means” comprising combining means (30, XH) dependent on the type of the image features having inputs for the weighting control vector (11, VC) and the image data [I(x)] and having an aspect for weighted adaptive kernels (35, H) adapted to the type of the image features to produce the filtered image signal [H(x)], and/or “post-mixing filtering means” comprising both isotropic and anisotropic filtering means [15, gi)] applied independently of the type of the image features, whose outputs (Gi) are combined at each image point and adapted using the weighting control vector (11, VC) to produce the filtered image signal [G(x)].
摘要翻译：图像处理系统，用于生成要应用于d维图像的点强度的多维自适应取向滤波器，包括具有用于在每个图像点处估计存在的概率测度（Fi）的装置（5，fi）的分析装置一种感兴趣的特征的类型，以及发布由所述概率测量构成的加权控制向量（11，VC）的加权控制模型（10），用于在每个图像点处控制合成的自适应内核; 以及合成装置，用于在适于感兴趣特征的类型的每个图像点处产生滤波器核，其滤波强度由加权控制矢量控制。该系统可以包括选择单元（40），用于用户选择合成装置，用于产生“预混合滤波装置”，该装置包括取决于具有用于加权控制矢量的输入的图像特征的类型的组合装置（30，XH） 11，VC）和图像数据[I（x）]，并且具有适于图像特征的类型的加权自适应内核（35，H）的方面以产生滤波图像信号[H（x）]，和/ 或“后混合滤波装置”，其包括独立于图像特征的类型的各向同性和各向异性滤波装置[15，gi]]，其输出（Gi）在每个图像点被组合并且使用加权控制矢量 11，VC）以产生滤波图像信号[G（x）]。

68. 发明申请

US20080317370A1 Method and System for Filtering Elongated Features 审中-公开
标题翻译：过滤长度特征的方法和系统
公开(公告)号：US20080317370A1
公开(公告)日：2008-12-25
申请号：US12092868
申请日：2006-11-02
申请人： Raoul Florent , Christophe Samson
发明人： Raoul Florent , Christophe Samson
IPC分类号： G06K9/40
CPC分类号： G06T5/20 , G06K9/4619 , G06K2209/057
摘要： The present invention relates to a method of filtering an input image for producing an output image. The method comprising the steps of, for a first image point located at first spatial coordinates:—analysing intensity levels of the input image in a first vicinity of the first image point for calculating a first direction of filtering at said first image point;—computing an intensity level of a first output image point of a first output image by applying a first steerable filter kernel to the input image, which is centered at the first image point and oriented along the calculated first direction of filtering; selecting at least a second image point in a second vicinity of said first image point in the first output image;—computing an intensity level of at least one second output image point of a second output image by applying at least a second steerable filter kernel to the input image, which is centered at the at least second image point and oriented along a second direction of filtering;—calculating a linear combination of the first output image point and of the at least second output image point for providing an output intensity level;—applying said output intensity level to an output image point of said output image, said output image point having said first spatial coordinates.
摘要翻译：本发明涉及一种滤波输出图像以产生输出图像的方法。该方法包括以下步骤：对于位于第一空间坐标处的第一图像点：在第一图像点的第一附近分析输入图像的强度水平，以计算所述第一图像点处的第一滤波方向; - 计算通过将第一可转向过滤器内核施加到以所计算的第一滤波方向为中心的第一图像点为中心的输入图像的第一输出图像点的强度水平; 在所述第一输出图像中的所述第一图像点的第二附近选择至少第二图像点; - 通过将至少第二可控滤波器核应用到第二输出图像的至少一个第二输出图像点的强度水平所述输入图像以所述至少第二图像点为中心并沿着第二滤波方向定向;计算所述第一输出图像点和所述至少第二输出图像点的线性组合以提供输出强度水平; 将所述输出强度电平施加到所述输出图像的输出图像点，所述输出图像点具有所述第一空间坐标。

69. 发明授权

US06968078B2 Image processing method, system and examination apparatus for extracting a threadlike structure in a noisy digital image 失效
标题翻译：用于在噪声数字图像中提取线状结构的图像处理方法，系统和检查装置
公开(公告)号：US06968078B2
公开(公告)日：2005-11-22
申请号：US09855629
申请日：2001-05-15
申请人： Raoul Florent , Lucil Goubet
发明人： Raoul Florent , Lucil Goubet
IPC分类号： A61B6/12 , A61B6/00 , G06T1/00 , G06T5/00 , G06T7/60 , G06K9/00
CPC分类号： G06T7/149 , G06T7/12 , G06T7/181 , G06T2207/10121 , G06T2207/20161 , G06T2207/30021
摘要： An image processing method for extracting a thread-like structure (GW) represented on the background in a digital noisy original image (IM1), comprising steps of acquisition (1) of the original image data; extraction (2) of elementary pixel strings (A1,A2,.) associated in string sets (SA,SB,SC), each of a same threadlike structure, forming a string set image (IM2); operation (4) of a First Phase (Intra-Set Phase) automatically yielding one Best String (A,B,C) per string set (INSI); and/or operation (5) of a Second Phase (Extra-Set Phase) automatically yielding one Final Best String (FBS) by linking Best Strings or elementary strings when the Second Phase is directly carried out (EXSI), for representing the threadlike structure (GW). Application: Medical Imaging; X-ray apparatus with image processing means and display means.
摘要翻译：一种用于提取在数字噪声原始图像（IM 1）中在背景上表示的线状结构（GW）的图像处理方法，包括以下步骤：获取（1）原始图像数据; 提取（2）与字符串组（SA，SB，SC）相关联的基本像素串（A 1，A 2，...），每个相同的线状结构，形成字符串集合图像（IM 2）; 第一阶段（内部设置阶段）的操作（4）自动产生每个字符串集（INSI）的一个最佳字符串（A，B，C）; 和/或第二阶段（额外设置阶段）的操作（5）通过在直接执行第二阶段（EXSI）时链接最佳字符串或基本字符串来自动产生一个最终最佳字符串（FBS），用于表示线状结构（GW）。应用：医学影像; 具有图像处理装置和显示装置的X射线装置。

70. 发明授权

US5911012A Method for the temporal filtering of the noise in an image of a sequence of digital images, and device for carrying out the method 失效
标题翻译：用于对数字图像序列的图像中的噪声进行时间滤波的方法以及用于执行该方法的装置
公开(公告)号：US5911012A
公开(公告)日：1999-06-08
申请号：US674061
申请日：1996-07-01
申请人： Franck Bernard , Raoul Florent
发明人： Franck Bernard , Raoul Florent
IPC分类号： G06T5/20 , G06T5/00 , G06K9/40
CPC分类号： G06T5/002 , G06T5/50 , G06T2207/10016 , G06T2207/10121 , G06T2207/20182 , G06T2207/30004
摘要： A method for the temporal filtering of a sequence of digitized noisy images includes the evaluation of an anti-causal filtered sample (P.sub.t.sup.A) in order to reconstruct a present noisy sample (I.sub.t.sup.P) of a given pixel in a present image by an anti-causal linear combination of a causal filtered sample (P.sub.t.sup.C) obtained by preliminary causal linear temporal filtering in association with coefficients (b.sub.j.sup.C) and an anti-causal noisy sample (I.sub.t+1.sup.A). To the samples (P.sub.t.sup.C, I.sub.t+1.sup.A) there are assigned weights calculated as functions of a causal gain factor (K.sub.t.sup.C), equal to the inverse of the sum of the coefficients of the causal linear filtering, and an anti-causal continuity coefficient (.alpha..sub.t.sup.A), the weight of the anti-causal sample (I.sub.t+1.sup.A) being equal to the probability of intensity continuity between the anti-causal sample (I.sub.t+1.sup.A) and a previous filtered sample (P.sub.t.sup.C, P.sub.t-1.sup.C) in the sequence. A device for carrying out the method is configured for calculating the anti-causal linear combination.
摘要翻译：用于时间过滤数字化噪声图像序列的方法包括反因果滤波样本（PtA）的评估，以便通过反因果重建当前图像中给定像素的当前噪声样本（ItP）通过与系数（bjC）和反因果嘈杂样本（It + 1A）相关联的初步因果线性时间滤波获得的因果滤波样本（PtC）的线性组合。对于样本（PtC，It + 1A），分配的权重作为因果增益因子（KtC）的函数计算，等于因果线性滤波的系数之和的倒数和反因果连续性系数 αtA），抗因子样品（It + 1A）的重量等于抗因子样品（It + 1A）与先前经过过滤的样品（PtC，Pt-1C）之间的强度连续性概率序列。用于执行该方法的装置被配置用于计算反因果线性组合。

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