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61. 发明授权

US07892331B2 Dialysis systems having air separation chambers with internal structures to enhance air removal 有权
标题翻译：透析系统具有具有内部结构的空气分离室，以增强排气
公开(公告)号：US07892331B2
公开(公告)日：2011-02-22
申请号：US11865583
申请日：2007-10-01
申请人： Robert W. Childers , Donald D. Busby , Michael E. Hogard , Michael R. Prisco , Atif M. Yardimci , James C. Laird
发明人： Robert W. Childers , Donald D. Busby , Michael E. Hogard , Michael R. Prisco , Atif M. Yardimci , James C. Laird
IPC分类号： B01D19/00
CPC分类号： A61M1/1658 , A61M1/166 , A61M1/3627 , A61M2205/128
摘要： A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including a first sidewall and a second sidewall, a first fluid opening, a second fluid opening, and a separation wall extending from the first sidewall to the second sidewall, the separation wall having a free edge residing within the air separation chamber, the separation wall forcing the dialysis fluid to flow from one of the fluid openings around the free edge of the separation wall to the other of the openings.
摘要翻译：透析液体盒包括限定至少一个阀室的刚性部分，所述刚性部分还限定空气分离室，所述空气分离室处于包括第一侧壁和第二侧壁的操作位置时，所述空气分离室，第一流体开口，第二流体开口流体开口和从第一侧壁延伸到第二侧壁的分隔壁，分隔壁具有位于空气分离室内的自由边缘，分隔壁迫使透析流体围绕自由边缘的一个流体开口流动的隔离壁到另一个开口。

62. 发明申请

US20090088675A1 FLUID AND AIR HANDLING IN BLOOD AND DIALYSIS CIRCUITS 有权
标题翻译：血液和空气处理在血液和透析电路
公开(公告)号：US20090088675A1
公开(公告)日：2009-04-02
申请号：US12237160
申请日：2008-09-24
申请人： Thomas D. Kelly , Marc S. Minkus , Angelito A. Bernardo , William P. Burns , Robert W. Childers , Shincy J. Maliekkal , Matthew R. Muller , Justin B. Rohde , Michael E. Hogard
发明人： Thomas D. Kelly , Marc S. Minkus , Angelito A. Bernardo , William P. Burns , Robert W. Childers , Shincy J. Maliekkal , Matthew R. Muller , Justin B. Rohde , Michael E. Hogard
IPC分类号： A61M1/10 , B01D61/32
CPC分类号： A61M1/3643 , A61M1/16 , A61M1/1601 , A61M1/282 , A61M1/288 , A61M1/3624 , A61M1/3627 , A61M1/3644 , A61M1/3649 , A61M2202/02 , A61M2202/0413 , A61M2205/10 , A61M2205/3382 , A61M2205/3386 , A61M2205/75 , Y10T137/0402
摘要： An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.
摘要翻译：空气净化方法包括：（a）检测表示血液回路中大量空气的血液循环中的低液位; （b）停止血液泵; （c）关闭静脉病人线; （d）打开血液循环通气阀和排水阀; 和（e）运行血液泵通过排气阀和排水阀将空气流通到排水管。

63. 发明申请

US20090084719A1 DIALYSIS SYSTEMS HAVING AIR SEPARATION CHAMBERS WITH INTERNAL STRUCTURES TO ENHANCE AIR REMOVAL 有权
标题翻译：具有内部结构的空气分离室的透析系统，以增强空气的去除
公开(公告)号：US20090084719A1
公开(公告)日：2009-04-02
申请号：US11865583
申请日：2007-10-01
申请人： Robert W. Childers , Donald D. Busby , Michael E. Hogard , Michael R. Prisco , Atif M. Yardimci , James C. Laird
发明人： Robert W. Childers , Donald D. Busby , Michael E. Hogard , Michael R. Prisco , Atif M. Yardimci , James C. Laird
IPC分类号： B01D35/01
CPC分类号： A61M1/1658 , A61M1/166 , A61M1/3627 , A61M2205/128
摘要： A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including a first sidewall and a second sidewall, a first fluid opening, a second fluid opening, and a separation wall extending from the first sidewall to the second sidewall, the separation wall having a free edge residing within the air separation chamber, the separation wall forcing the dialysis fluid to flow from one of the fluid openings around the free edge of the separation wall to the other of the openings.
摘要翻译：透析液体盒包括限定至少一个阀室的刚性部分，所述刚性部分还限定空气分离室，所述空气分离室处于包括第一侧壁和第二侧壁的操作位置时，所述空气分离室，第一流体开口，第二流体开口流体开口和从第一侧壁延伸到第二侧壁的分隔壁，分隔壁具有位于空气分离室内的自由边缘，分隔壁迫使透析流体围绕自由边缘的一个流体开口流动的隔离壁到另一个开口。

64. 发明申请

US20090012461A1 DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE AND HEATED CASSETTE INTERFACE 有权
标题翻译：具有可分散CASSETTE和加热CASSETTE界面的透析系统
公开(公告)号：US20090012461A1
公开(公告)日：2009-01-08
申请号：US11773756
申请日：2007-07-05
申请人： Robert W. Childers , Bruce E. Huitt
发明人： Robert W. Childers , Bruce E. Huitt
IPC分类号： A61M1/14
CPC分类号： A61M1/28 , A61M1/284 , A61M1/288 , A61M2205/128 , A61M2205/3396 , A61M2209/084
摘要： A dialysis fluid flow control system includes a pumping cassette interface including a pump area operable with a pump chamber of a disposable cassette; the cassette interface further including a volumetric reference chamber used in a volumetric control of a dialysis fluid pumped pneumatically into and out of the pump chamber of the disposable cassette; a heater connected operably to the cassette interface; and a controller connected operably to the heater so as to cause the heater to heat at least a portion of the cassette interface to a desired temperature.
摘要翻译：透析液流量控制系统包括泵壳接口，其包括可与一次性盒的泵室一起操作的泵区; 所述盒式接口还包括体积参考室，所述体积参考室用于气动地进入和离开所述一次性盒的泵室的透析液的体积控制; 可操作地连接到盒接口的加热器; 以及可操作地连接到加热器的控制器，以便使加热器将盒接口的至少一部分加热到所需温度。

65. 发明申请

US20090012457A1 DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE AND INTERFACE THEREFORE 有权
标题翻译：具有可处理CASSETTE和接口的DIALYSIS系统
公开(公告)号：US20090012457A1
公开(公告)日：2009-01-08
申请号：US11773787
申请日：2007-07-05
申请人： Robert W. Childers , Peter A. Hopping
发明人： Robert W. Childers , Peter A. Hopping
IPC分类号： A61M1/14
CPC分类号： A61M1/28 , A61M1/16 , A61M1/1605 , A61M1/166 , A61M1/284 , A61M1/288 , A61M1/341 , A61M2205/122 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368
摘要： A medical fluid flow control system includes an interface including a first pump area, the first pump area of the interface including a pneumatic actuator port and a gasket seal port; and a membrane gasket including a second pump area for mating with the first pump area, the second pump area including a blind section which covers the pneumatic actuator port when the gasket is mated with the interface, the second pump area further including an aperture, the aperture sized and positioned to seal around the gasket seal port, allowing a negative pressure to be applied through the gasket seal port to a flexible sheet of a pumping cassette.
摘要翻译：医疗流体流量控制系统包括界面，该界面包括第一泵区域，界面的第一泵区域包括气动致动器端口和垫圈密封端口; 以及膜垫片，其包括用于与所述第一泵区域配合的第二泵区域，所述第二泵区域包括当所述垫圈与所述接口配合时覆盖所述气动致动器端口的盲区，所述第二泵区域还包括孔，孔径尺寸和定位成围绕垫圈密封端口密封，允许通过垫圈密封端口将负压施加到泵送盒的柔性片。

66. 发明申请

US20090012454A1 DIALYSIS SYSTEM HAVING NON-INVASIVE TEMPERATURE SENSING 有权
标题翻译：具有非入侵温度感测的透析系统
公开(公告)号：US20090012454A1
公开(公告)日：2009-01-08
申请号：US11773746
申请日：2007-07-05
申请人： Robert W. Childers
发明人： Robert W. Childers
IPC分类号： A61M1/14
CPC分类号： A61M1/28 , A61M1/284 , A61M1/288 , A61M5/44 , A61M39/14 , A61M2205/122 , A61M2205/3368 , G01J5/089
摘要： A dialysis system includes a dialysis instrument; a disposable item configured to hold a dialysis fluid and including an at least substantially opaque portion and an at least substantially clear portion; at least one non-invasive temperature sensor mounted to the dialysis instrument so as to be pointed selectively at the at least substantially clear portion and the at least substantially opaque portion; and a processor configured to calculate a temperature of the dialysis fluid within the disposable item using (i) a first temperature measurement from the at least one sensor while pointed at the at least substantially opaque portion, and (ii) a second temperature measurement from the at least one sensor pointed at the at least substantially clear portion.
摘要翻译：透析系统包括透析仪器; 配置成保持透析流体并且包括至少基本上不透明的部分和至少基本上清楚的部分的一次性物品; 至少一个非侵入式温度传感器，其被安装到所述透析仪器上，以便被选择性地指向所述至少基本上透明的部分和所述至少基本上不透明的部分; 以及处理器，被配置为使用（i）来自所述至少一个传感器的第一温度测量来计算所述一次性物品内的透析液的温度，同时指向所述至少基本上不透明的部分，以及（ii）来自所述至少一个传感器的第二温度测量至少一个传感器指向至少基本上清晰的部分。

67. 发明授权

US07238164B2 Systems, methods and apparatuses for pumping cassette-based therapies 有权
标题翻译：用于抽取基于盒式疗法的系统，方法和装置
公开(公告)号：US07238164B2
公开(公告)日：2007-07-03
申请号：US10335646
申请日：2002-12-31
申请人： Robert W. Childers , Richard Avoy , John Booras , Joseph H. Bowman, Jr. , Paul Grippo , Andrew D. Hopping , David Howard , Jeffrey W. Jerrell , Benjamin Kellam , Brian Lauman , Sherwin Shang , David Vescovi , Tahua Yang , Alex Yu
发明人： Robert W. Childers , Richard Avoy , John Booras , Joseph H. Bowman, Jr. , Paul Grippo , Andrew D. Hopping , David Howard , Jeffrey W. Jerrell , Benjamin Kellam , Brian Lauman , Sherwin Shang , David Vescovi , Tahua Yang , Alex Yu
IPC分类号： A61M37/00 , C02F1/44 , F04B45/04 , C02F9/00
CPC分类号： A61M1/281 , A61M1/16 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M2205/122
摘要： The present invention provides systems, methods and apparatuses for medical fluid delivery systems that employ a pumping cassette. In particular, the present invention provides systems, methods and apparatuses for cassette-based dialysis therapies including hemodialysis, hemofiltration, APD (including tidal modalities) and CFPD. The embodiments described include a combined pump/valve housing, a fail safe pump/valve arrangement, a cassette auto-alignment feature, a pumping membrane material, a multiplexing valve arrangement, an expert fluid pumping management system, an integral port vent and an in-line air separation chamber and combinations of each of these.
摘要翻译：本发明提供了采用抽吸盒的医用流体输送系统的系统，方法和装置。特别地，本发明提供了用于基于盒式透析疗法的系统，方法和装置，包括血液透析，血液滤过，APD（包括潮气模式）和CFPD。所描述的实施例包括组合泵/阀壳体，故障安全泵/阀装置，盒自动对准特征，泵送膜材料，复用阀装置，专家流体泵送管理系统，整体通气口和入口线空气分离室及其组合。

68. 发明授权

US07107837B2 Capacitance fluid volume measurement 有权
公开(公告)号：US07107837B2
公开(公告)日：2006-09-19
申请号：US10054487
申请日：2002-01-22
申请人： Brian Lauman , Pete Hopping , Rick Kienman , Shahid Din , Robert W. Childers
发明人： Brian Lauman , Pete Hopping , Rick Kienman , Shahid Din , Robert W. Childers
IPC分类号： G01F23/26
CPC分类号： G01F23/263 , A61M1/1658 , A61M1/28 , A61M1/284 , A61M1/287 , A61M5/14216 , A61M5/14224 , A61M5/16831 , A61M2205/3317 , A61M2205/3379
摘要： A fluid volumetric pumping system has a fluid pump and capacitor plates disposed around a pump chamber of the fluid pump. The capacitance between the capacitor plates changes as the volume of fluid in the pump chamber changes. An electrical circuit measures a change in the capacitance between the plates and outputs a signal indicative of the volume of fluid in the pump chamber. The pump having the capacitance sensor of the present invention fluidly connects to a patient. In an embodiment, a peritoneal dialysis system provides dialysate to the patient via the pump, and the capacitance sensor measures the volume of dialysate supplied to and drained from a peritoneal cavity of the patient.

69. 发明授权

US5876664A Continuous-operation, closed loop decontamination system and method 失效
标题翻译：连续操作，闭环净化系统及方法
公开(公告)号：US5876664A
公开(公告)日：1999-03-02
申请号：US664985
申请日：1996-06-14
申请人： Robert W. Childers , Stephen G. Geist , Paul A. Steen
发明人： Robert W. Childers , Stephen G. Geist , Paul A. Steen
IPC分类号： A61L2/20 , A61L2/24 , G05D23/19 , G05D23/00 , A61L9/00 , B01J7/00
CPC分类号： A61L2/208 , A61L2/24 , G05D23/1935 , A61L2202/122 , A61L2202/24
摘要： The invention provides a method and apparatus for minimizing heat degradation of a vapor decontaminant in a vaporizer by selectively operating a plurality of vaporizer heaters to provide a decreasing heat gradient through the vaporizer. A method and apparatus are also provided for selectively operating a plurality of preheaters, in series, for preheating a carrier gas entering a vaporizer in a flow-through decontamination system, and for maintaining a predetermined carrier gas temperature. A further method and apparatus are provided for fine-tuning chamber pressure in a high flow rate closed-loop flow-through vapor phase decontamination system.
摘要翻译：本发明提供了一种用于通过选择性地操作多个蒸发器加热器以减少通过蒸发器的热梯度来最小化汽化器中的蒸气去污剂的热降解的方法和装置。还提供了一种方法和装置，用于选择性地操作多个串联的预热器，用于预热在流通净化系统中进入蒸发器的载气，并保持预定的载气温度。提供了一种用于在高流量闭环流通气相净化系统中微调腔室压力的方法和装置。

70. 发明授权

US5830409A Method to shorten aeration after a sterilization cycle 失效
标题翻译：在灭菌周期后缩短通气的方法
公开(公告)号：US5830409A
公开(公告)日：1998-11-03
申请号：US582731
申请日：1996-01-04
申请人： Robert W. Childers , Steven J. Edwards , Donald R. Gagne , Cory J. Palmer
发明人： Robert W. Childers , Steven J. Edwards , Donald R. Gagne , Cory J. Palmer
IPC分类号： A61L2/20 , A61L9/00
CPC分类号： A61L2/20
摘要： Hot, saturated water vapor in the form of low-temperature subatmospheric steam is employed to shorten the aeration period after sterilization with a condensable, heat-labile chemical sterilant. The application of steam accelerates the rate of outgassing of sterilant residuals that are absorbed into, or adsorbed or condensed onto chamber or load materials. The method is particularly suitable for removing residuals from polymeric materials and/or materials that are poor heat conductors. Apparatus is provided to supply steam in situations where a utility steam supply is not available.
摘要翻译：使用低温低于大气压蒸汽形式的热的饱和水蒸气来缩短用可冷凝的热不稳定的化学灭菌剂灭菌后的通气时间。蒸汽的应用加速了吸收或吸附或冷凝到室或负载材料上的灭菌剂残留物的除气速率。该方法特别适于从聚合材料和/或不良热导体的材料中除去残余物。在没有公用蒸汽供应的情况下提供设备来提供蒸汽。

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