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61. 发明授权

US5641780A Pyrrolo-indole derivatives 失效
标题翻译：吡咯 - 吲哚衍生物
公开(公告)号：US5641780A
公开(公告)日：1997-06-24
申请号：US564178
申请日：1995-12-15
申请人： Nobuyoshi Amishiro , Satoru Nagamura , Hiromitsu Saito , Eiji Kobayashi , Akihiko Okamoto , Katsushige Gomi
发明人： Nobuyoshi Amishiro , Satoru Nagamura , Hiromitsu Saito , Eiji Kobayashi , Akihiko Okamoto , Katsushige Gomi
IPC分类号： C07D487/04 , A61K31/495
CPC分类号： C07D487/04
摘要： DC-89 derivatives represented by the formula ##STR1## wherein X represents CL or Br; R represents substituted or unsubstituted alkyl, substituted or unsubstituted aralkyl, COR.sup.1 or S.sub.2 OR.sup.7 ; and Y represents ##STR2## and pharmaceutically acceptable salts thereof. The compounds of the present invention exhibit excellent anti-tumor activity and are useful as anti-tumor agents.
摘要翻译： PCT No.PCT / JP95 / 00779 371 1995年12月15日第 102（e）1995年12月15日PCT PCT 1995年4月20日提交PCT公布。公开号WO95 / 29179 日期为1995年11月2日，由式表示的取代或未取代的烷基，取代或未取代的芳烷基，COR1或S2OR7的DC-89衍生物; Y表示“IMAGE”或“IMAGE”及其药学上可接受的盐。本发明的化合物表现出优异的抗肿瘤活性，可用作抗肿瘤剂。

62. 发明授权

US5536850A Substance DC114-A1 失效
标题翻译：物质DC114-A1
公开(公告)号：US5536850A
公开(公告)日：1996-07-16
申请号：US392886
申请日：1995-03-01
申请人： Hirofumi Nakano , Noboru Fujii , Tamio Mizukami , Youichi Uosaki , Katsunori Kita , Eiji Kobayashi
发明人： Hirofumi Nakano , Noboru Fujii , Tamio Mizukami , Youichi Uosaki , Katsunori Kita , Eiji Kobayashi
IPC分类号： A61K31/35 , A61P31/04 , A61P35/00 , C07D493/04 , C12P17/18 , C07D311/78 , C07D311/94
CPC分类号： C07D493/04 , C12P17/181
摘要： The present invention relates to a novel substance DC114-A1 represented by the following formula (I): ##STR1##
摘要翻译： PCT No.PCT / JP94 / 00956 Sec。 371 1995年3月1日 102（e）1995年3月1日PCT 1994年6月14日PCT公布。第WO95 / 01981号公报 1995年1月19日。本发明涉及由下式（I）表示的新型物质DC114-A1：（I）

63. 发明授权

US5332740A DC-89 derivatives 失效
标题翻译： DC-89衍生物
公开(公告)号：US5332740A
公开(公告)日：1994-07-26
申请号：US46365
申请日：1993-04-13
申请人： Hiromitsu Saito , Satoru Nagamura , Akira Asai , Eiji Kobayashi , Katsushige Gomi
发明人： Hiromitsu Saito , Satoru Nagamura , Akira Asai , Eiji Kobayashi , Katsushige Gomi
IPC分类号： C07D471/04 , A61K31/435 , A61K31/495 , C07D487/04
CPC分类号： C07D471/04
摘要： Novel DC-89 derivatives represented by general formula (I): ##STR1## wherein X represents Cl or Br; R.sup.1 represents hydrogen, CONR.sup.2 R.sup.3 (in which R.sup.2 and R.sup.3 independently represent hydrogen, a straight-chain or branched alkyl group having 1 to 4 carbon atoms or phenyl group), ##STR2## (in which n represents an integer of 4 to 7), ##STR3## (in which R.sup.4 represents oxygen, N--CH.sub.3 or N--CH.sub.2 CH.sub.2 NH.sub.2), ##STR4## (in which R.sup.5 R.sup.6 and R.sup.7 independently represent a straight-chain or branched alkyl group having 1 to 4 carbon atoms); and ##STR5## (in which Y represents hydrogen or CO.sub.2 CH.sub.3); provided that when R.sup.1 is hydrogen, CONR.sup.2 R.sup.3 or SiR.sup.5 R.sup.6 R.sup.7, ##STR6## and pharmaceutically acceptable salts thereof have an excellent anti-tumor activity and are expected to be useful as anti-tumor compositions.
摘要翻译：由通式（I）表示的新型DC-89衍生物：其中X表示Cl或Br; R1表示氢，CONR2R3（其中R2和R3独立地表示氢，具有1至4个碳原子的直链或支链烷基或苯基），其中n表示4至7的整数，（其中R 4表示氧，N-CH 3或N-CH 2 CH 2 NH 2），其中R 5和R 7独立地表示碳原子数1〜4的直链或支链烷基。和其中Y表示氢或CO 2 CH 3）。条件是当R 1是氢时，CONR 2 R 3或SiR 5 R 6 R 7，其药学上可接受的盐具有优异的抗肿瘤活性，并且预期可用作抗肿瘤组合物。

64. 发明授权

US4992570A UCN-1028A and UCN-1028C and process for the production thereof 失效
标题翻译： UCN-1028A和UCN-1028C及其生产方法
公开(公告)号：US4992570A
公开(公告)日：1991-02-12
申请号：US173174
申请日：1988-03-24
申请人： Hirofumi Nakano , Eiji Kobayashi , Isami Takahashi , Katsuhiko Ando , Mayumi Yoshida , Shiro Akinaga , Takao Iida
发明人： Hirofumi Nakano , Eiji Kobayashi , Isami Takahashi , Katsuhiko Ando , Mayumi Yoshida , Shiro Akinaga , Takao Iida
IPC分类号： C12P15/00
CPC分类号： C12P15/00 , Y10S435/911
摘要： UCN-1028A and UCN-1028C having an anti-tumor activity and a protein kinase C inhibitory activity are produced by culturing a microorganism belonging to the genus Cladosporium.

65. 发明授权

US4226158A Damper assembly for keyboard musical instruments 失效
标题翻译：键盘乐器减震器总成
公开(公告)号：US4226158A
公开(公告)日：1980-10-07
申请号：US000376
申请日：1978-12-29
申请人： Eiji Kobayashi , Hiroyoshi Takahashi
发明人： Eiji Kobayashi , Hiroyoshi Takahashi
IPC分类号： G10C3/16
CPC分类号： G10C3/166
摘要： In the construction of a damper assembly for musical instruments, the conventionally used swingable damper lever for operationally relating a key to an associated damper wire is omitted and the swing movement of the key is either directly and indirectly converted into a corresponding fairly vertical movement of an elongated damper holder via a balance weight disposed to the bottom end of the damper holder in order to avoid undesired influences caused by swinging movement of any mechanical parts. Use of a plate type damper holder further advantageously prevents undesirable twist and dancing of the damper holder. Simultaneous, even and well-controlled pressure contact of the damper head with the vibrating string assures ideal damping and acoustic effects and use of detachable balance weight enables free adjustment of touch on the key.
摘要翻译：在用于乐器的阻尼器组件的构造中，省略了常规使用的可操作地将钥匙与相关联的阻尼线相关联的可摆动阻尼器杆，并且钥匙的摆动运动被直接地和间接地转换成相应的相当垂直的运动通过设置在阻尼器保持器的底端的平衡配重的细长阻尼器保持器，以避免由任何机械部件的摆动所引起的不期望的影响。使用板式阻尼器支架进一步有利地防止阻尼器保持器的不期望的扭转和跳动。阻尼头与振动弦的同时，均匀和良好的压力接触确保理想的阻尼和声音效果，并使用可拆卸的平衡重，可以自由调节钥匙上的触感。

66. 发明授权

US3950185A Film removing compositions 失效
标题翻译：电影去除组合物
公开(公告)号：US3950185A
公开(公告)日：1976-04-13
申请号：US467841
申请日：1974-05-07
申请人： Mitsuo Toyama , Toshio Ito , Eiji Kobayashi , Hideo Kosaka
发明人： Mitsuo Toyama , Toshio Ito , Eiji Kobayashi , Hideo Kosaka
IPC分类号： B08B7/00 , B44D3/16 , C09D9/00 , C09J5/00 , C11D7/50 , B08B7/04
CPC分类号： B08B7/0014 , C09D9/005
摘要： A film removing composition consisting essentially of at least one halogenated hydrocarbon solvent as a major solvent and a pressure-sensitive adhesive component such as synthetic resins, and mixtures of natural rubber or synthetic rubbers and tackifiers.When the film removing composition is applied to a paint film to be removed, and a paper or cloth is put on the film removing composition and then peeled off, the paint film can be removed together with the paper or cloth.

67. 发明授权

US10087421B2 Stem cell suspension 有权
公开(公告)号：US10087421B2
公开(公告)日：2018-10-02
申请号：US13883371
申请日：2011-11-09
申请人： Eiji Kobayashi , Tamaki Wada , Yasutaka Fujita , Norihiro Yoshinaga , Masako Doi , Yasuhiro Fujimoto , Takumi Teratani
发明人： Eiji Kobayashi , Tamaki Wada , Yasutaka Fujita , Norihiro Yoshinaga , Masako Doi , Yasuhiro Fujimoto , Takumi Teratani
IPC分类号： C12N5/071 , C07H3/04 , C12N5/0775 , A01N1/02 , A61K9/00 , A61K47/26 , A61K47/36 , A61K35/28 , C08B31/04 , C08B37/02
摘要： The present invention provides a mammalian stem cell suspension containing mammalian stem cells and at least one polysaccharide such as trehalose, and the like; a mammalian stem cell aggregation inhibitor containing polysaccharide such as trehalose, and the like; a method of suppressing aggregation of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharide; an inhibitor of a decrease in the survival rate of mammalian stem cells containing polysaccharide such as trehalose and the like; a method of suppressing a decrease in the survival rate of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharides, and the like.

68. 发明授权

US09208037B2 Duplexed operation processor control system, and duplexed operation processor control method 有权
公开(公告)号：US09208037B2
公开(公告)日：2015-12-08
申请号：US12457682
申请日：2009-06-18
申请人： Toshiki Shimizu , Akira Bando , Yusaku Otsuka , Yasuhiro Kiyofuji , Eiji Kobayashi , Akihiro Onozuka , Satoru Funaki , Masakazu Ishikawa , Hideaki Masuko , Yusuke Seki , Wataru Sasaki , Naoya Mashiko , Akihiro Nakano , Shin Kokura , Shoichi Ozawa , Yu Iwasaki
发明人： Toshiki Shimizu , Akira Bando , Yusaku Otsuka , Yasuhiro Kiyofuji , Eiji Kobayashi , Akihiro Onozuka , Satoru Funaki , Masakazu Ishikawa , Hideaki Masuko , Yusuke Seki , Wataru Sasaki , Naoya Mashiko , Akihiro Nakano , Shin Kokura , Shoichi Ozawa , Yu Iwasaki
IPC分类号： G06F11/20 , G06F11/16 , G06F9/445
CPC分类号： G06F11/2033 , G06F8/656 , G06F11/1658 , G06F11/2028 , G06F11/2038 , G06F11/2097
摘要： The present invention provides a duplexed operation processor control system that includes operation processors, an I/O device, and at least one communication path that couples the operation processors to the I/O device, and at least one communication path that couples the operation processors with each other. The duplexed operation processor control system switches over either of the operation processors to be a primary operation processor that executes a control operation for a control target, and the other to be a secondary operation processor that is in a stand-by state, and the secondary operation processor snoops control data synchronously when the primary operation processor acquires the control data from the control target.

69. 发明授权

US08887610B2 Capstan device 有权
标题翻译：绞盘装置
公开(公告)号：US08887610B2
公开(公告)日：2014-11-18
申请号：US13879126
申请日：2012-01-12
申请人： Eiji Kobayashi , Osamu Tamada
发明人： Eiji Kobayashi , Osamu Tamada
IPC分类号： D04C3/48 , H01B13/00 , H01B13/26
CPC分类号： H01B13/00 , H01B13/2606
摘要： A capstan device for taking up a braided wire in a braided wire manufacturing apparatus for braiding a plurality of wires to manufacture the braided wire. The capstan device includes a capstan roller having a tapered outer peripheral surface and provided with a flange portion on an end at a small diameter side thereof, and a guide member. The guide member has a first guide surface provided to be turned toward a large diameter side of the capstan roller in an axial direction of the capstan roller in a position on a larger diameter side than a portion having the smallest diameter in the tapered outer peripheral surface, and a second guide surface provided to be protruded from the first guide surface at an outer peripheral side of the tapered outer peripheral surface.
摘要翻译：一种用于在编织线制造装置中卷绕编织线的绞盘装置，用于编织多根线以制造编织线。绞盘装置包括具有锥形外周面的主导辊，并且在其小直径侧的端部上设置有凸缘部分和引导构件。引导构件具有第一引导表面，该第一引导表面设置成沿着主动轮的轴向方向朝向主动轮的大直径侧在比在锥形外周面中具有最小直径的部分更大直径侧的位置以及设置成在锥形外周面的外周侧从第一引导面突出的第二引导面。

70. 发明授权

US08871440B2 Method for evaluation of tissue preservation solution 有权
标题翻译：组织保存液评价方法
公开(公告)号：US08871440B2
公开(公告)日：2014-10-28
申请号：US12450116
申请日：2008-01-18
申请人： Eiji Kobayashi
发明人： Eiji Kobayashi
IPC分类号： C12Q1/68 , A01N1/00 , C12Q1/00 , G01N33/50 , C12Q1/66
CPC分类号： C12Q1/6816 , C12Q1/66 , G01N33/5082
摘要： The present invention provides a method for evaluating preservative effect of a tissue preservation solution, comprising immersing a mammalian tissue introduced with a luminescence or fluorescence labeling gene in the tissue preservation solution, measuring a luminescence or fluorescence level by the labeling gene in the tissue after immersion, and evaluating the preservative effect of the tissue preservation solution based on the luminescence or fluorescence level.
摘要翻译：本发明提供一种评价组织保存溶液的防腐效果的方法，其特征在于，将组合保存液中引入了发光或荧光标记基因的哺乳动物组织浸渍，浸渍后的组织中的标记基因测定发光或荧光水平，并基于发光或荧光水平评估组织保存溶液的防腐效果。

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