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61. 发明申请

US20080212793A1 Arrangement structure of sound system in motorcycle 有权
标题翻译：摩托车音响系统布置结构
公开(公告)号：US20080212793A1
公开(公告)日：2008-09-04
申请号：US12007006
申请日：2008-01-04
申请人： Takayuki Kai , Kazuhlko Mori , Atsushi Hatayama , Junichi Sakamoto
发明人： Takayuki Kai , Kazuhlko Mori , Atsushi Hatayama , Junichi Sakamoto
IPC分类号： H04B1/00
CPC分类号： B60R11/0217
摘要： To provide an arrangement structure of a sound system in a motorcycle which can ensure the operability of a sound operation unit while ensuring the visibility of a meter. In a motorcycle which arranges a meter indicating information on a vehicle and a sound operation unit for providing a reproduction operation or the like in a sound system in the vicinity of a steering portion, the meter and the sound operation unit are constituted as bodies separate from each other. The meter and the sound operation unit are arranged, as viewed in the axial direction of a head pipe which supports a steering portion, in front of and behind the head pipe.
摘要翻译：为了提供摩托车中的声音系统的布置结构，其能够确保声音操作单元的可操作性，同时确保仪表的可视性。在将在车辆上指示信息的计时器的摩托车和用于在转向部附近的声音系统中提供再现操作等的声音操作单元，仪表和声音操作单元构成为与彼此。在支管转向部的头管的轴向观察时，仪表和声音操作单元布置在头管的前面和后面。

62. 发明授权

US06924300B2 Oxyiminoalkanoic acid derivatives 失效
公开(公告)号：US06924300B2
公开(公告)日：2005-08-02
申请号：US10331056
申请日：2002-12-27
申请人： Yu Momose , Hiroyuki Odaka , Hiroshi Imoto , Hiroyuki Kimura , Junichi Sakamoto
发明人： Yu Momose , Hiroyuki Odaka , Hiroshi Imoto , Hiroyuki Kimura , Junichi Sakamoto
IPC分类号： A61K31/195 , A61K31/235 , A61K31/42 , A61K31/421 , A61K31/422 , A61K31/4245 , A61K31/426 , A61K31/427 , A61K31/437 , A61K31/44 , A61K31/4402 , A61K31/4439 , A61K31/47 , A61K31/4704 , A61K31/4745 , A61K31/496 , A61K31/505 , A61P3/06 , A61P3/10 , A61P9/10 , A61P29/00 , A61P43/00 , C07D213/74 , C07D215/14 , C07D239/42 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D413/04 , C07D413/12 , C07D471/04 , C07D263/30 , C07D277/20
CPC分类号： C07D213/74 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/427 , A61K31/44 , A61K31/4439 , A61K31/47 , A61K31/4745 , A61K31/505 , C07D215/14 , C07D239/42 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D413/12 , C07D471/04
摘要： To provide a novel oxyiminoalkanoic acid derivative which has excellent hypoglycemic and hypolipidemic actions and which is used for the prevention or treatment of diabetes mellitus, hyperlipemia, insulin insensitivity, insulin resistance and impaired glucose tolerance.A compound represented by the formula: wherein R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a bond, —CO—, —CH(OH)— or a group represented by —NR6— wherein R6 is a hydrogen atom or an optionally substituted alkyl group; n is an integer of 1 to 3; Y is an oxygen atom, a sulfur atom, —SO—, —SO2— or a group represented by —NR7— wherein R7 is a hydrogen atom or an optionally alkyl group; ring A is a benzene ring optionally having additional one to three substituents; p is an integer of 1 to 8; R2 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; q is an integer of 0 to 6; m is 0 or 1; R3 is a hydroxy group, OR8 (R8 is an optionally substituted hydrocarbon group.) or NR9R10 (R9 and R10 are the same or different groups which are selected from a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group or an optionally substituted acyl group or R9 and R10 combine together to form a ring); R4 and R5 are the same or different groups which are selected from a hydrogen atom or an optionally substituted hydrocarbon group wherein R4 may form a ring with R2; provided that when R1 is a ethoxymethyl, a C1-3 alkyl, phenyl or p-methoxyphenyl and q=m=0, R3 is NR9R10; and provided that O-[2-chloro-4-(2-quinolylmethoxy)phenylmethyl]oxime and a methyl pyruvate of [2-chloro-4-(2-quinolylmethoxy)phenylmethyl]-2-iminoxypropionic acid are excluded; or a salt thereof.

63. 发明授权

US06495581B1 Oxyiminoalkanoic acid derivatives 失效
标题翻译：氧亚氨基链烷酸衍生物
公开(公告)号：US06495581B1
公开(公告)日：2002-12-17
申请号：US09714699
申请日：2000-11-16
申请人： Yu Momose , Hiroyuki Odaka , Hiroshi Imoto , Hiroyuki Kimura , Junichi Sakamoto
发明人： Yu Momose , Hiroyuki Odaka , Hiroshi Imoto , Hiroyuki Kimura , Junichi Sakamoto
IPC分类号： A61K31425
CPC分类号： C07D213/74 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/427 , A61K31/44 , A61K31/4439 , A61K31/47 , A61K31/4745 , A61K31/505 , C07D215/14 , C07D239/42 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D413/12 , C07D471/04
摘要： A compound represented by the formula: wherein R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a bond, —CO—, —CH(OH)— or a group represented by —NR6— wherein R6 is a hydrogen atom or an optionally substituted alkyl group; n is an integer of 1 to 3; Y is an oxygen atom, a sulfur atom, —SO—, —SO2— or a group represented by —NR7— wherein R7 is a hydrogen atom or an optionally alkyl group; ring A is a benzene ring optionally having additional one to three substituents; p is an integer of 1 to 8; R2 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; q is an integer of 0 to 6; m is 0 or 1; R3 is a hydroxy group, OR8 (R8 is an optionally substituted hydrocarbon group.) or NR9R10 (R9 and R10 are the same or different groups which are selected from a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group or an optionally substituted acyl group or R9 and R10 combine together to form a ring); R4 and R5 are the same or different groups which are selected from a hydrogen atom or an optionally substituted hydrocarbon group wherein R4 may form a ring with R2; provided that when R1 is a ethoxymethyl, a C1-3 alkyl, phenyl or p-methoxyphenyl and q=m=0, R3 is NR9R10; and provided that O-[2-chloro-4-(2-quinolylmethoxy)phenylmethyl]oxime and a methyl pyruvate of [2-chloro-4-(2-quinolylmethoxy)phenylmethyl]-2-iminoxypropionic acid are excluded; or a salt thereof which has excellent hypoglycemic and hypolipidemic actions.
摘要翻译：由下式表示的化合物：其中R1是任选取代的烃基或任选取代的杂环基; X是键，-CO - ， - CH（OH） - 或-NR 6 - 表示的基团，其中R 6是氢原子或任选取代的烷基; n为1〜3的整数。 Y是氧原子，硫原子，-SO-，-SO 2 - 或-NR 7 - 表示的基团，其中R 7是氢原子或任意烷基; 环A是任选具有另外一个至三个取代基的苯环; p为1〜8的整数， R2是氢原子，任选取代的烃基或任选取代的杂环基; q为0〜6的整数; m为0或1; R3是羟基，OR8（R8是任选取代的烃基）或NR9R10（R9和R10是相同或不同的基团，其选自氢原子，任选取代的烃基，任选取代的杂环基或任选取代的酰基或R 9和R 10结合在一起形成环）; R4和R5是选自氢原子或任选取代的烃基的相同或不同的基团，其中R 4可以与R 2形成环; 条件是当R1是乙氧基甲基，C1-3烷基，苯基或对甲氧基苯基且q = m = 0时，R3是NR9R10; 并且排除了[2-氯-4-（2-喹啉基甲氧基）苯基甲基] -2-亚氨基丙酸的O- [2-氯-4-（2-喹啉基甲氧基）苯甲基]肟和丙酮酸甲酯。或其盐，其具有优异的降血糖和降血脂作用。

64. 发明授权

US06394561B1 Brake system for vehicles with routine judgment of normal operation of pressure sensors 有权
标题翻译：用于常规判断压力传感器正常运行的车辆制动系统
公开(公告)号：US06394561B1
公开(公告)日：2002-05-28
申请号：US09365222
申请日：1999-07-30
申请人： Junichi Sakamoto , Akihiro Otomo
发明人： Junichi Sakamoto , Akihiro Otomo
IPC分类号： B60T888
CPC分类号： B60T8/4081 , B60T8/94 , B60T17/221
摘要： In a brake system of a vehicle in which a pair of wheel cylinders are supplied with a fluid pressure by a fluid circuit having a pair of inlet control valves for selectively connecting the pair of wheel cylinders respectively to an outlet port of a motor-driven pump and a pair of outlet control valves for selectively connecting the pair of wheel cylinders respectively to a fluid reservoir, a brake control device controls the motor driving of the pump and opening/closing of the inlet and outlet control valves, such that a controlled fluid pressure is supplied to the pair of wheel cylinders at least temporarily with the pair of inlet control valves substantially fully opened, while the pair of outlet control valves substantially closed, wherein it is judged if there is a difference between output signals of a pair of wheel cylinder pressure sensors beyond a predetermined threshold value, thereby judging the pair of wheel cylinder pressure sensors to be both operating normally when the difference is not larger than the threshold value.
摘要翻译：在车辆的制动系统中，其中通过具有一对入口控制阀的流体回路向一对轮缸供给流体压力，所述流体回路分别选择性地将所述一对轮缸分别连接到电动泵的出口以及一对出口控制阀，用于将所述一对轮缸分别选择性地连接到流体储存器，制动控制装置控制所述泵的马达驱动和所述入口和出口控制阀的打开/关闭，使得受控流体压力至少暂时供给一对轮缸，一对进气控制阀基本上完全打开，而一对出口控制阀基本上关闭，其中判断一对轮缸的输出信号是否有差异超过预定阈值的压力传感器，从而判断一对轮缸压力传感器在二级运转时正常运行参数不大于阈值。

65. 发明授权

US06193330B1 Electrically controlled brake system shut down by turn off of ignition switch with delay time 有权
标题翻译：电控制动系统通过点火开关关闭，延时
公开(公告)号：US06193330B1
公开(公告)日：2001-02-27
申请号：US09217839
申请日：1998-12-22
申请人： Masayuki Soga , Yutaka Ohnuma , Junichi Sakamoto
发明人： Masayuki Soga , Yutaka Ohnuma , Junichi Sakamoto
IPC分类号： B60T888
CPC分类号： B60T8/4081 , B60T7/12 , B60T13/686 , B60T17/18
摘要： An electrically controlled brake system for a vehicle, wherein an electric control device of the system has a device for detecting a changeover of an ignition switch from an on-state to an off-state. The electrically controlled brake system also includes a device for detecting a depression of a brake pedal beyond a predetermined depth. The brake system has a device for counting a predetermined time duration when the ignition switch changeover detection device detects a changeover of the ignition switch from the on-state to the off-state. Furthermore, the electrically controlled brake system includes a device for shutting down the electrically controlled brake system when the time count device has counted the predetermined time duration and the brake pedal depression detection device fails to detect the brake pedal depression beyond the predetermined depth.
摘要翻译：一种用于车辆的电控制动系统，其中所述系统的电气控制装置具有用于检测点火开关从接通状态切换到关闭状态的装置。电控制动系统还包括用于检测超过预定深度的制动踏板的下压的装置。制动系统具有用于在点火开关切换检测装置检测到点火开关从接通状态切换到断开状态时的预定持续时间的计数装置。此外，电控制动系统包括当时间计数装置计数预定持续时间并且制动踏板下压检测装置未能检测到超过预定深度的制动踏板压力时关闭电控制动系统的装置。

66. 发明授权

US5756806A Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same 失效
标题翻译：氰基苯硫基卤化物及使用其制备3-取代苯并异噻唑的方法
公开(公告)号：US5756806A
公开(公告)日：1998-05-26
申请号：US861426
申请日：1997-05-21
申请人： Hiroshi Goda , Junichi Sakamoto , Shigeki Sakaue , Sakae Kajihara , Miki Todo
发明人： Hiroshi Goda , Junichi Sakamoto , Shigeki Sakaue , Sakae Kajihara , Miki Todo
IPC分类号： C07C313/08 , C07C313/16 , C07D275/04 , C07C255/49
CPC分类号： C07D275/04 , C07C313/08 , C07C313/16
摘要： The present invention provides a compound represented by the general formula (I): ##STR1## wherein X represents Cl or Br, a process for preparation of the same and a process for preparation of 3-substituted benzisothiazole by reaction of the compound (I) with a piperazine compound.
摘要翻译：本发明提供由通式（I）表示的化合物：其中X表示Cl或Br，其制备方法和通过化合物的反应制备3-取代的苯并异噻唑的方法（I）与哌嗪化合物。

67. 发明授权

US5725959A Antireflection film for plastic optical element 失效
标题翻译：塑料光学元件防反射膜
公开(公告)号：US5725959A
公开(公告)日：1998-03-10
申请号：US754475
申请日：1996-11-22
申请人： Junji Terada , Makoto Kameyama , Junichi Sakamoto
发明人： Junji Terada , Makoto Kameyama , Junichi Sakamoto
IPC分类号： G02B1/11 , B32B9/04
CPC分类号： G02B1/115 , Y10T428/264 , Y10T428/31667
摘要： An antireflection film is procided on a plastic optical element as follows. An undercoat composed principally of unsaturated silicon exide SiO.sub.x (2>x>1) with a thickness within a range of 200 to 300 nm is formed on the optical element. A multi-layered film of a repeating structure is formed on the undercoat. The multi-layerd film has antireflective characteristics. The undercoat has a refractive index within a range of 1.49 to 1.59. The multi-layered film is composed of alternate lamination of a layer of a material which has a high refractive index and which is composed principally of TiO.sub.2, ZrO.sub.2 or a mixture thereof, and a layer of a material which has a low refractive index and which is composed principally of SiO.sub.x (2.gtoreq.x.gtoreq.1).
摘要翻译：如下在塑料光学元件上进行防反射膜的制作。在光学元件上形成厚度在200〜300nm范围内的主要由不饱和硅离子SiO x（2> x> 1）组成的底涂层。在底涂层上形成重复结构的多层膜。多层膜具有抗反射特性。底涂层的折射率在1.49〜1.59的范围内。多层膜由具有高折射率且主要由TiO 2，ZrO 2或其混合物组成的材料层的交替叠层和具有低折射率的材料层组成，并且其中主要由SiOx（2> / = x> / = 1）组成。

68. 发明授权

US5679827A Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same 失效
标题翻译：氰基苯硫基卤化物及使用其制备3-取代苯并异噻唑的方法
公开(公告)号：US5679827A
公开(公告)日：1997-10-21
申请号：US630730
申请日：1996-04-10
申请人： Hiroshi Goda , Junichi Sakamoto , Shigeki Sakaue , Sakae Kajihara , Miki Todo
发明人： Hiroshi Goda , Junichi Sakamoto , Shigeki Sakaue , Sakae Kajihara , Miki Todo
IPC分类号： C07C313/08 , C07C313/16 , C07D275/04 , C07C255/49
CPC分类号： C07D275/04 , C07C313/08 , C07C313/16
摘要： The present invention provides a compound represented by the general formula (I): ##STR1## wherein X represents Cl or Br, a process for preparation of the same and a process for preparation of 3-substituted benzisothiazole by reaction of the compound (I) with a piperazine compound.
摘要翻译：本发明提供由通式（I）表示的化合物：其中X表示Cl或Br，其制备方法和通过化合物的反应制备3-取代的苯并异噻唑的方法（I）与哌嗪化合物。

69. 发明授权

US5643550A Method of treating colorectal carcinoma lesion and composition for use therein 失效
标题翻译：治疗结肠直肠癌病变的方法及其组合物
公开(公告)号：US5643550A
公开(公告)日：1997-07-01
申请号：US312633
申请日：1994-09-27
申请人： Sydney Welt , Chaitanya R. Divgi , Samual Yeh , Lloyd J. Old , Herbert F. Oettgen , Francisco X. Real , Junichi Sakamoto
发明人： Sydney Welt , Chaitanya R. Divgi , Samual Yeh , Lloyd J. Old , Herbert F. Oettgen , Francisco X. Real , Junichi Sakamoto
IPC分类号： A61K51/10 , C07K16/30 , A61K51/00 , A61K35/14 , A61K49/00
CPC分类号： A61K51/1063 , C07K16/3046 , A61K2039/505 , A61K2121/00 , C07K2317/24 , C07K2317/55 , Y10S436/808 , Y10S436/813 , Y10S530/808 , Y10S530/809 , Y10S530/837
摘要： This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the colorectal carcinoma lesion and which is labeled with an imaging agent under conditions so as to form a complex between the monoclonal antibody and the cell surface antigen, imaging any complex so formed, and thereby imaging the colorectal carcinoma lesion.This invention also provides a monoclonal antibody designated AS 33 (ATCC Accession No. HB 8779) and the hybridoma which produces it.
摘要翻译：本发明提供了一种对人类患者的结肠直肠癌病变进行成像的方法，其包括向患者施用能够结合与结肠直肠癌病变相关的细胞表面抗原的单克隆抗体，并在成像剂的条件下进行标记，在单克隆抗体和细胞表面抗原之间形成复合物，对如此形成的任何复合物进行成像，从而对结肠直肠癌病变进行成像。本发明还提供了称为AS33（ATCC登录号HB 8779）和产生它的杂交瘤的单克隆抗体。

70. 发明授权

US5578536A Evaporating material for producing optical thin film 失效
标题翻译：用于生产光学薄膜的蒸发材料
公开(公告)号：US5578536A
公开(公告)日：1996-11-26
申请号：US428800
申请日：1995-04-24
申请人： Makoto Kameyama , Noboru Sugahara , Mitsuharu Sawamura , Junji Terada , Junichi Sakamoto
发明人： Makoto Kameyama , Noboru Sugahara , Mitsuharu Sawamura , Junji Terada , Junichi Sakamoto
IPC分类号： C23C14/08 , C23C14/24 , G02B1/10 , G02B1/115 , G02B5/28 , C04B35/46 , C04B35/48
CPC分类号： G02B5/285 , G02B1/10
摘要： An evaporation material is employed to form an optical thin film which is adapted to be formed on an optical element such as a lens or the like. The evaporation material is provided such that zirconium oxide (ZrO.sub.2) is mixed with a titanium oxide (TiO.sub.A) having a molar ratio A(O/Ti) of oxygen to titanium in a range of 1.0 to 1.75 so that the mixture assumes a molar ratio (Ti/Zr) of titanium to zirconium in a range of 1.0 to 4.0. The mixture is sintered or fused and solidified.
摘要翻译：采用蒸发材料形成适于形成在诸如透镜等的光学元件上的光学薄膜。提供蒸发材料，使得氧化锆（ZrO 2）与氧摩尔比A（O / Ti）至钛的氧化钛（TiOA）与1.0至1.75的范围内混合，使得混合物呈现摩尔比（Ti / Zr）为1.0〜4.0的钛。混合物烧结或熔融固化。

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