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61. 发明授权

US07658723B2 Catheter having plurality of stiffening members 有权
标题翻译：导管具有多个加强构件
公开(公告)号：US07658723B2
公开(公告)日：2010-02-09
申请号：US11439592
申请日：2006-05-23
申请人： Randolf Von Oepen , Axel Grandt , Andrew Jeffrey , Guenter Lorenz
发明人： Randolf Von Oepen , Axel Grandt , Andrew Jeffrey , Guenter Lorenz
IPC分类号： A61M25/00
CPC分类号： A61M25/10 , A61M25/0021 , A61M25/0029 , A61M25/0032 , A61M25/0043 , A61M29/00 , A61M2025/0063 , A61M2025/0183 , A61M2025/1056
摘要： The invention includes a catheter having an elongate main body having a proximal section and a distal section. The elongate main body further includes a plurality of stiffening members disposed along the length of the elongate main body. The plurality of stiffening members includes a first stiffening member and a second stiffening member. The catheter can also include a balloon formed from a tubular member having a recess defined in a portion of its surface. A tapered or thinned balloon is formed from a process by which material is removed from a tubular member prior to formation of the balloon.
摘要翻译：本发明包括具有细长主体的导管，该主体具有近端部分和远端部分。细长主体还包括沿着细长主体的长度设置的多个加强构件。多个加强构件包括第一加强构件和第二加强构件。导管还可以包括由管状构件形成的气囊，所述管状构件具有限定在其表面的一部分中的凹部。从形成气囊之前从管状构件移除材料的过程形成锥形或变薄的球囊。

62. 发明授权

US07645260B2 Catheter having auxiliary lumen 有权
标题翻译：导管有辅助管腔
公开(公告)号：US07645260B2
公开(公告)日：2010-01-12
申请号：US11390327
申请日：2006-03-27
申请人： Ib Erling Joergensen , Randolf Von Oepen
发明人： Ib Erling Joergensen , Randolf Von Oepen
IPC分类号： A61M29/00
CPC分类号： A61M25/0029 , A61M25/10 , A61M2025/0183 , C09J151/06
摘要： The present invention relates to a surgical catheter, and more particularly, a balloon catheter having an auxiliary lumen configured to permit the advancement of a functional measurement wire to a treatment site. The auxiliary lumen communicates with a working lumen that is configured to permit the advancement of a guidewire and the functional measurement wire, so that the guidewire and functional measurement wire may selectively be advanced to the treatment site during a surgical procedure.
摘要翻译：技术领域本发明涉及一种外科导管，更具体地说，涉及具有配置为允许将功能测量导线推进到治疗部位的辅助腔的球囊导管。辅助管腔与被配置为允许推进导丝和功能测量线的工作腔连通，使得导引线和功能测量线可以在外科手术期间选择性地前进到治疗部位。

63. 发明授权

US07527606B2 Catheter having main body portion with coil-defined guidewire passage 有权
标题翻译：导管具有主体部分，具有线圈限定的导丝通道
公开(公告)号：US07527606B2
公开(公告)日：2009-05-05
申请号：US11136251
申请日：2005-05-23
申请人： Randolf Von Oepen
发明人： Randolf Von Oepen
IPC分类号： A61M31/00
CPC分类号： A61M25/0054 , A61M25/0021 , A61M25/0043 , A61M25/005 , A61M25/0052 , A61M25/0053 , A61M25/10 , A61M2025/1056
摘要： The invention includes a catheter having an elongate main body portion and a distal body portion. The elongate main body portion has a proximal end and a distal end. The main body portion further includes a coil having at least one complete turn about a central axis, the coil defining a passage along the central axis. The elongate distal body portion extends from the distal end of the main body portion. In accordance with a further aspect of the invention, the distal body portion has a proximal end and a distal end and can include a guidewire lumen defined along at least a portion of a length between the distal end and the proximal end of the distal body portion. The guidewire lumen has a distal guidewire port and a proximal guidewire port defined in communication therewith. The passage can be in fluid communication with an exterior of the catheter.
摘要翻译：本发明包括具有细长主体部分和远侧主体部分的导管。细长主体部分具有近端和远端。主体部分还包括具有围绕中心轴线至少一个完整的线圈的线圈，线圈限定了沿中心轴线的通道。细长的远侧主体部分从主体部分的远端延伸。根据本发明的另一方面，远侧主体部分具有近端和远端，并且可以包括沿远端本体部分的远端和近端之间的长度的至少一部分限定的导丝内腔。导丝管腔具有与之连通的远端导丝端口和近端导丝端口。通道可以与导管的外部流体连通。

64. 发明申请

US20080045896A1 Catheter having intermediate position markers 审中-公开
标题翻译：导管具有中间位置标记
公开(公告)号：US20080045896A1
公开(公告)日：2008-02-21
申请号：US11506309
申请日：2006-08-17
申请人： Travis R. Yribarren , Randolf Von Oepen , Arik Zucker , Lorcan Coffey , Thomas Rieth
发明人： Travis R. Yribarren , Randolf Von Oepen , Arik Zucker , Lorcan Coffey , Thomas Rieth
IPC分类号： A61M29/00 , A61M31/00 , A61M37/00
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954 , A61F2250/0098 , A61M2025/105 , A61M2025/1072
摘要： Various improved catheter marking arrangements are described. In a first aspect of the invention, the catheter includes an expandable member (such as for example, a balloon, a stent, etc.). A pair of radiopaque end markers mark the distal and proximal ends of the expandable member. Additionally, a radiopaque intermediate marker is provided that marks an intermediate position on the expandable member. The intermediate marker may be used to mark important points on the expandable member. The markers are sized and positioned such that a surgeon utilizing the catheter in a surgical procedure would be able to readily differentiate the markers in a fluoroscopic image to determine the location of the item marked by the orientation of the catheter. In various other aspects of the invention, the intermediate marker is arranged to mark a position on the expandable member that constitutes a line of demarcation for an agent (such as a drug) carried by a balloon.
摘要翻译：描述了各种改进的导管标记装置。在本发明的第一方面，导管包括可扩张构件（例如气球，支架等）。一对不透射线的端标记标记可扩张构件的远端和近端。另外，提供标记可扩张构件上的中间位置的不透射线的中间标记。中间标记可用于标记可扩张构件上的重要点。标记物的大小和定位使得在外科手术中利用导管的外科医生将能够容易地在荧光透视图像中区分标记物，以确定由导管的取向标记的物品的位置。在本发明的各种其他方面，中间标记被布置成标记可膨胀构件上构成由气球承载的试剂（例如药物）的界线的位置。

65. 发明申请

US20070270755A1 GUIDEWIRE HANDLING DEVICE 审中-公开
标题翻译： GUIDEWIRE处理设备
公开(公告)号：US20070270755A1
公开(公告)日：2007-11-22
申请号：US11738420
申请日：2007-04-20
申请人： Randolf Von Oepen , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Richard Newhauser , Travis Yribarren
IPC分类号： A61M25/09
CPC分类号： A61M25/09041 , A61M2025/0008 , A61M2025/09116 , A61M2025/09125 , B25B9/00
摘要： This invention describes a guidewire handling device for creating an indicium and/or urging a guidewire. A guidewire handling device is provided that includes a device body having a guidewire passage sized to receive a guidewire. A clamping member is coupled to the device body and is movable between a first and second position. The guidewire handling device includes a visible marker that provides visible feedback regarding the angular orientation of the guidewire handling device. In addition, the guidewire handling device includes a contoured surface that allows the torque applied to the guidewire handling device to be dependent on the location where the torque is applied.
摘要翻译：本发明描述了一种用于创建标记和/或推动导丝的导丝处理装置。提供了一种导丝处理装置，其包括具有尺寸适于接收导丝的导丝通道的装置主体。夹紧构件联接到装置主体并且能够在第一和第二位置之间移动。导丝处理装置包括可见标记，其提供关于导丝处理装置的角度取向的可见反馈。此外，导丝处理装置包括允许施加到导丝线处理装置的扭矩取决于施加扭矩的位置的轮廓表面。

66. 发明申请

US20070213802A1 Bifurcation Stent Delivery Catheter and Method 审中-公开
标题翻译：分叉支架输送导管和方法
公开(公告)号：US20070213802A1
公开(公告)日：2007-09-13
申请号：US11683899
申请日：2007-03-08
申请人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
IPC分类号： A61F2/84
CPC分类号： A61F2/95
摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel, first and second inflatable members disposed adjacent the distal end of the elongated shaft and an endoprosthesis disposed about the first and second inflatable members. The delivery system further includes a tip assembly which during to advancement of the delivery system is configured as a single tip assembly, wherein prior to deployment of the expandable endoprosthesis, the tip assembly is split into a first tip and a second tip, wherein one of the tips remains in a main branch and the second tip is advanced into a side branch lumen to align the endoprosthesis prior to deployment.
摘要翻译：公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。递送系统包括细长的柔性管状轴，其尺寸适于插入身体容器中，邻近细长轴的远端设置的第一和第二可膨胀构件以及围绕第一和第二可膨胀构件设置的内假体。输送系统还包括尖端组件，其在输送系统的进行期间被配置为单个尖端组件，其中在展开可膨胀内置假体之前，将尖端组件分成第一尖端和第二尖端，其中，尖端保持在主分支中，并且第二尖端前进到侧分支内腔以在部署之前对准内假体。

67. 发明申请

US20070060910A1 Multiple lumen catheter and method of making same 有权
标题翻译：多腔导管及其制作方法
公开(公告)号：US20070060910A1
公开(公告)日：2007-03-15
申请号：US11439596
申请日：2006-05-23
申请人： Axel Grandt , Randolf Von Oepen , Andrew Jeffrey , Bodo Quint , Stevan Nielsen , Thomas Rieth
发明人： Axel Grandt , Randolf Von Oepen , Andrew Jeffrey , Bodo Quint , Stevan Nielsen , Thomas Rieth
IPC分类号： A61M25/00
CPC分类号： A61M25/0032 , A61F2/958 , A61M25/0009 , A61M25/0023 , A61M25/0045 , A61M25/005 , A61M25/0053 , A61M25/0054 , A61M25/008 , A61M25/10 , A61M2025/0183
摘要： The invention provides a catheter and method of making the same including an outer tubular member having a length, an outer surface, an inner surface and a lumen therethrough. The catheter also includes an inner tubular member having an outer surface, an inner surface and a lumen therethrough, at least a length of the inner lumen is disposed in the lumen of the outer tubular member. The catheter also includes a support member biasing a portion of the outer surface of the inner tubular member against a portion of the inner surface of the outer tubular member.
摘要翻译：本发明提供一种导管及其制造方法，其包括具有长度，外表面，内表面和通过其的内腔的外管状构件。导管还包括具有外表面，内表面和通过其的内腔的内管状构件，内管腔的至少一段长度设置在外管状构件的内腔中。导管还包括支撑构件，该支撑构件偏压内管状构件的外表面的一部分抵靠外管状构件的内表面的一部分。

68. 发明申请

US20060106418A1 Apparatus for sealing surgical punctures 有权
标题翻译：用于密封手术穿刺的装置
公开(公告)号：US20060106418A1
公开(公告)日：2006-05-18
申请号：US10523166
申请日：2003-07-25
申请人： Gerd Seibold , Kenneth Michlitsch , Randolf Von Oepen , Bodo Quint , Ib Joergensen
发明人： Gerd Seibold , Kenneth Michlitsch , Randolf Von Oepen , Bodo Quint , Ib Joergensen
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/0643 , A61B2017/00004 , A61B2017/00477 , A61B2017/00659
摘要： Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
摘要翻译：提供了用于密封容器或组织内的穿刺以提供止血的装置，包括联接到第二盘或弹簧的第一盘，并密封地接合到围绕穿刺的容器或组织。至少第一盘优选地构造成在展开时基本上符合血管或组织的轮廓。在一个实施例中，盘可以从与血管或组织的接合中释放，以在部署之后重新定位椎间盘。

69. 发明申请

US20060100665A1 Apparatus for sealing punctures in blood vessels 审中-公开
标题翻译：用于密封血管穿刺的装置
公开(公告)号：US20060100665A1
公开(公告)日：2006-05-11
申请号：US10523217
申请日：2003-07-25
申请人： Randolf Von Oepen , Gerd Seibold , Ib Joergensen , Kenneth Michlitsch , Stevan Nielsen , Tommy Conzelmann , Bodo Quint
发明人： Randolf Von Oepen , Gerd Seibold , Ib Joergensen , Kenneth Michlitsch , Stevan Nielsen , Tommy Conzelmann , Bodo Quint
IPC分类号： A61B17/04
CPC分类号： A61B17/12013 , A61B17/0057 , A61B2017/00349 , A61B2017/00637 , A61B2017/00659 , A61B2017/00672 , A61B2017/0406 , A61B2017/0496
摘要： Apparatus is provided for sealing a puncture in a blood vessel using at least one device that applies an internal compressive force upon a distal surface of the vessel. The devices preferably are deployable distal of the distal surface of the vessel, then retracted proximally to provide the internal compressive force, e.g., to promote coagulation and facilitate sealing of the puncture. Additionally, the devices of the present invention optionally may be used in combination with known techniques that provide an external compressive force upon an exterior surface of a patient's skin to expedite sealing of the puncture.
摘要翻译：提供了使用至少一个在血管的远端表面上施加内部压缩力的装置来密封血管中的穿刺的装置。装置优选地可展开在血管远侧表面的远端，然后向近侧缩回以提供内部压缩力，例如促进凝结并便于穿刺的密封。另外，本发明的装置可以任意地与已知技术组合使用，这些技术在患者皮肤的外表面上提供外部压缩力，以加速穿刺的密封。

70. 发明申请

US20050004662A1 Methods and apparatus for a drug-coated stent having an expandable web structure 有权
标题翻译：具有可扩张腹板结构的药物涂层支架的方法和装置
公开(公告)号：US20050004662A1
公开(公告)日：2005-01-06
申请号：US10909117
申请日：2004-07-30
申请人： Randolf Von Oepen , Gerd Seibold
发明人： Randolf Von Oepen , Gerd Seibold
IPC分类号： A61F2/06 , A61F2/90
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558
摘要： The present invention provides a drug-coated stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected by transition sections. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.
摘要翻译：本发明提供了一种药物涂层支架，其包括管状柔性体，该管状柔性体具有壁，所述壁具有可从收缩输送构型扩展到展开构造的腹板结构。网状结构包括多个相邻的网状图案，其中每个网状图案由邻接的网构成，并且网状图案通过过渡部分相互连接。每个邻接的腹板包括插入在两个横向部分之间以形成凹形或凸形构造的中心部分。

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