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61. 发明授权

US07438693B2 Devices and methods for performing procedures on a breast 失效
标题翻译：用于在乳房上执行手术的装置和方法
公开(公告)号：US07438693B2
公开(公告)日：2008-10-21
申请号：US11145808
申请日：2005-06-06
申请人： James W. Vetter , Scott C. Anderson , Jordon S. Tuttle , Daniel M. Brounstein
发明人： James W. Vetter , Scott C. Anderson , Jordon S. Tuttle , Daniel M. Brounstein
IPC分类号： A61B10/00
CPC分类号： A61B90/39 , A61B10/02 , A61B18/14 , A61B2090/3908
摘要： A needle is used to mark a tissue area of interest. The needle may have one or more indicators which indicate selected angular orientations relative to the needle. The indicators may also be coupled to anchors which are deployed in the tissue to anchor the needle in the tissue. The needle may be positioned to guide an excisional device to remove tissue.
摘要翻译：针用于标记感兴趣的组织区域。针可以具有一个或多个指示器，其指示相对于针的所选角度取向。指示器还可以联接到部署在组织中的锚固件以将针固定在组织中。针可以定位成引导切除装置以去除组织。

62. 发明申请

US20080140067A1 METHODS AND DEVICES FOR CUTTING AND COLLECTING SOFT TISSUE 审中-公开
标题翻译：用于切割和收集软组织的方法和装置
公开(公告)号：US20080140067A1
公开(公告)日：2008-06-12
申请号：US11836018
申请日：2007-08-08
申请人： James W. Vetter , Ary S. Chernomorsky , Mark J. Clifford , Dan Brounstein , Scott C. Anderson
发明人： James W. Vetter , Ary S. Chernomorsky , Mark J. Clifford , Dan Brounstein , Scott C. Anderson
IPC分类号： A61B18/18
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： A device for cutting and collecting a specimen from a mass of tissue may include a shaft, an integrated cut and collect assembly coupled to the shaft and an actuator. The shaft may define an opening and may include an outer surface that defines a trough adjacent the opening, the trough defining a ledge portion that is cut out of the shaft. The integrated cut and collect assembly may include an RF cutting portion and a collection portion that includes a flexible membrane, the collection portion being attached to the cutting portion, the integrated cut and collect assembly being configured to assume a retracted position at least partially within the opening such that part of the collection portion is disposed within the trough and in contact with the ledge portion and a selectable expanded position that extends through the opening and away from the shaft. The cutting portion may be configured to cut the specimen from the mass of tissue and the collection portion may be configured to collect the cut specimen and to isolate the cut specimen within the membrane. The trough may be configured to minimize contact of the cutting portion with the tissue to be cut as the cutting portion is becoming fully energized in the retracted position. The actuator may be coupled to the integrated assembly such that operation of the actuator causes a deployment of the integrated assembly from the retracted position to the selectable expanded position.
摘要翻译：用于从大量组织切割和收集试样的装置可以包括轴，与轴连接的集成切割和收集组件和致动器。轴可以限定开口并且可以包括限定靠近开口的槽的外表面，所述槽限定从轴切出的凸缘部分。集成的切割和收集组件可以包括RF切割部分和收集部分，其包括柔性膜，收集部分附接到切割部分，集成切割和收集组件被配置为呈现至少部分地在开口使得收集部分的一部分设置在槽内并与凸缘部分接触，并且可选择的扩展位置延伸穿过开口并远离轴。切割部分可以被配置为从组织块切割样本，并且收集部分可以被配置为收集切割的样品并将切割的样品隔离在膜内。槽可以被配置为当切割部分在缩回位置变得完全通电时使切割部分与要切割的组织的接触最小化。致动器可以联接到集成组件，使得致动器的操作使得整合组件从缩回位置展开到可选择的扩展位置。

63. 发明授权

US07122011B2 Methods and devices for cutting and collecting soft tissue 失效
公开(公告)号：US07122011B2
公开(公告)日：2006-10-17
申请号：US10601300
申请日：2003-06-18
申请人： Mark J. Clifford , Scott C. Anderson , James W. Vetter , Daniel M. Brounstein , Ary S. Chernomorsky
发明人： Mark J. Clifford , Scott C. Anderson , James W. Vetter , Daniel M. Brounstein , Ary S. Chernomorsky
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B18/1402 , A61B18/1492 , A61B2017/00287 , A61B2017/008 , A61B2018/00214 , A61B2018/00898 , Y10T83/04
摘要： Devices and methods for collecting or cutting and collecting a specimen from a mass of tissue within a patient. The device may include a specimen collection assembly including a flexible membrane that isolates collected specimen from the surrounding tissue. The collection device may also include structures that draw the collected specimen toward the shaft and/or otherwise ease the insertion and retraction of the device and the collected specimen from the patient through a small incision.

64. 发明授权

US07044956B2 Methods and devices for cutting and collecting soft tissue 有权
公开(公告)号：US07044956B2
公开(公告)日：2006-05-16
申请号：US10272452
申请日：2002-10-16
申请人： James W. Vetter , Ary S. Chernomorsky , Mark J. Clifford , Dan Brounstein , Scott C. Anderson
发明人： James W. Vetter , Ary S. Chernomorsky , Mark J. Clifford , Dan Brounstein , Scott C. Anderson
IPC分类号： A61B17/32
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.

65. 发明授权

US06936014B2 Devices and methods for performing procedures on a breast 失效
公开(公告)号：US06936014B2
公开(公告)日：2005-08-30
申请号：US10272448
申请日：2002-10-16
申请人： James W. Vetter , Scott C. Anderson , Jordan S. Tuttle , Daniel M. Brounstein
发明人： James W. Vetter , Scott C. Anderson , Jordan S. Tuttle , Daniel M. Brounstein
IPC分类号： A61B10/00 , A61B10/02 , A61B18/14 , A61B19/00
CPC分类号： A61B90/39 , A61B10/02 , A61B18/14 , A61B2090/3908
摘要： A needle is used to mark a tissue area of interest. The needle may have one or more indicators which indicate selected angular orientations relative to the needle. The indicators may also be coupled to anchors which are deployed in the tissue to anchor the needle in the tissue. The needle may be positioned to guide an excisional device to remove tissue.

66. 发明授权

US06764495B2 Excisional biopsy devices and methods 失效
公开(公告)号：US06764495B2
公开(公告)日：2004-07-20
申请号：US10098014
申请日：2002-03-14
申请人： Roberta Lee , James W. Vetter
发明人： Roberta Lee , James W. Vetter
IPC分类号： A61B1722
CPC分类号： A61B8/085 , A61B8/461 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/04 , A61B17/320725 , A61B18/1482 , A61B2017/00287 , A61B2018/00011 , A61B2018/1407 , A61B2018/1475 , A61B2090/3782 , A61B2090/3784 , A61B2218/002
摘要： An excisional biopsy device includes a tubular member having a window near a distal tip thereof; a cutting tool, a distal end of the cutting tool being attached near the distal tip of the tubular member, at least a distal portion of the cutting tool being configured to selectively bow out of the window and to retract within the window; and a tissue collection device externally attached at least to the tubular member, the tissue collection device collecting tissue excised by the cutting tool as the biopsy device is rotated and the cutting tool is bowed. An excisional biopsy method for soft tissue includes the steps of inserting a generally tubular member into the tissue, the tubular member including a cutting tool adapted to selectively bow away from the tubular member and an external tissue collection device near a distal tip of the tubular member; rotating the tubular member; selectively varying a degree of bowing of the cutting tool; collecting tissue severed by the cutting tool in the tissue collection device; and retracting the tubular member from the soft tissue. The tubular member may include an imaging transducer and the method may include the step of displaying information received from the transducer on a display device and the step of varying the degree of bowing of the cutting tool based upon the displayed information from the imaging transducer. Alternatively, the imaging transducer may be disposed within a removable transducer core adapted to fit within the tubular member.

67. 发明授权

US06689145B2 Excisional biopsy devices and methods 失效
标题翻译：切除活检装置和方法
公开(公告)号：US06689145B2
公开(公告)日：2004-02-10
申请号：US10066428
申请日：2002-01-31
申请人： Roberta Lee , James W. Vetter , Ary S. Chernomorsky
发明人： Roberta Lee , James W. Vetter , Ary S. Chernomorsky
IPC分类号： A61B1732
CPC分类号： A61B10/0266 , A61B10/0041 , A61B10/02 , A61B10/04 , A61B17/320725 , A61B18/1482 , A61B2018/00011 , A61B2018/00333 , A61B2018/1407 , A61B2018/1475 , A61B2090/3782 , A61B2090/3784 , A61B2218/002
摘要： An excisional biopsy system includes a tubular member that has a proximal end and a distal end in which one or more windows are defined. A first removable probe has a proximal portion that includes a cutting tool extender and a distal portion that includes a cutting tool. The first removable probe may be configured to fit at least partially within the tubular member to enable the cutting tool to selectively bow out of and to retract within one of the windows when the cutting tool extender is activated. A second removable probe has a proximal section that includes a tissue collection device extender and a distal section that includes a tissue collection device. The second removable probe may also be configured to fit at least partially within the tubular member to enable the tissue collection device to extend out of and to retract within one of the windows when the tissue collection device extender is activated. A third removable probe may also be provided. The third removable probe may also be configured to fit at least partially within the tubular member and may include an imaging device, such as an ultrasound transducer, mounted therein. By selectively activating the cutting tool and the tissue collection device while rotating the excisional device, a tissue specimen may be cut from the surrounding tissue and collected for later analysis.
摘要翻译：切除活检系统包括管状构件，其具有限定一个或多个窗口的近端和远端。第一可移除探针具有近端部分，其包括切削刀具延伸器和包括切削工具的远端部分。第一可移除探针可以被配置为至少部分地配合在管状构件内，以使得当切割工具延伸器被激活时，切割工具能够选择性地弯曲在一个窗口内并缩回。第二可移除探针具有近端部分，其包括组织收集装置延伸器和包括组织收集装置的远端部分。第二可移除探针也可以被配置为至少部分地配合在管状构件内，以使组织收集装置在组织收集装置延伸器被启动时延伸出窗口内的一个窗口并缩回。还可以提供第三可移除探针。第三可移除探针也可以被配置为至少部分地配合在管状构件内，并且可以包括安装在其中的成像装置，例如超声换能器。通过在旋转切除装置的同时选择性地激活切割工具和组织收集装置，可以从周围组织切割组织标本并收集用于随后的分析。

68. 发明授权

US06423081B1 Excisional biopsy devices and methods 失效
标题翻译：切除活检装置和方法
公开(公告)号：US06423081B1
公开(公告)日：2002-07-23
申请号：US09417520
申请日：1999-10-13
申请人： Roberta Lee , James W. Vetter
发明人： Roberta Lee , James W. Vetter
IPC分类号： A61B1722
CPC分类号： A61B8/085 , A61B8/461 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/04 , A61B17/320725 , A61B18/1482 , A61B2017/00287 , A61B2018/00011 , A61B2018/1407 , A61B2018/1475 , A61B2090/3782 , A61B2090/3784 , A61B2218/002
摘要： An excisional biopsy device includes a tubular member having a window near a distal tip thereof; a cutting tool, a distal end of the cutting tool being attached near the distal tip of the tubular member, at least a distal portion of the cutting tool being configured to selectively bow out of the window and to retract within the window; and a tissue collection device externally attached at least to the tubular member, the tissue collection device collecting tissue excised by the cutting tool as the biopsy device is rotated and the cutting tool is bowed. An excisional biopsy method for soft tissue includes the steps of inserting a generally tubular member into the tissue, the tubular member including a cutting tool adapted to selectively bow away from the tubular member and an external tissue collection device near a distal tip of the tubular member; rotating the tubular member; selectively varying a degree of bowing of the cutting tool; collecting tissue severed by the cutting tool in the tissue collection device; and retracting the tubular member from the soft tissue. The tubular member may include an imaging transducer and the method may include the step of displaying information received from the transducer on a display device and the step of varying the degree of bowing of the cutting tool based upon the displayed information from the imaging transducer. Alternatively, the imaging transducer may be disposed within a removable transducer core adapted to fit within the tubular member.
摘要翻译：切除活检装置包括：管状构件，其具有靠近其顶端的窗口; 切割工具，所述切割工具的远端附接在所述管状构件的远侧末端附近，所述切割工具的至少远端部分被配置为选择性地弯曲出窗外并在窗内缩回; 以及组织收集装置，其至少外部连接到所述管状构件，所述组织收集装置收集由所述活检装置旋转并且所述切割工具弯曲时由所述切割工具切除的组织。用于软组织的切除活检方法包括将大致管状构件插入组织的步骤，所述管状构件包括适于选择性地远离管状构件弓形的切割工具和在管状构件的远侧末端附近的外部组织收集装置 ; 旋转管状构件; 选择性地改变切割工具的弯曲程度; 收集由组织收集装置中的切割工具切断的组织; 并从软组织缩回管状构件。管状构件可以包括成像传感器，并且该方法可以包括在显示装置上显示从换能器接收的信息的步骤，以及基于来自成像换能器的显示的信息来改变切割工具的弯曲程度的步骤。或者，成像换能器可以设置在适于装配在管状构件内的可移除换能器芯内。

69. 发明授权

US06304770B1 Breast stabilization devices and imaging and interventional methods using same 失效
标题翻译：未压缩乳房的成像和介入方法
公开(公告)号：US06304770B1
公开(公告)日：2001-10-16
申请号：US09588033
申请日：2000-06-05
申请人： Roberta Lee , James W. Vetter , Natalie N. Hyland
发明人： Roberta Lee , James W. Vetter , Natalie N. Hyland
IPC分类号： A61B505
CPC分类号： A61B6/0414 , A61B6/502 , A61B90/17 , A61B2017/3411 , Y10S128/915
摘要： A breast stabilization device for imaging and invasive medical procedures includes a shell configured to surround a superior portion of a breast when the breast rests on a substantially flat surface. The shell includes a first opening configured to allow at least a portion of a nipple-areolar complex of the breast to protrude therethrough. A first and second flange extend from the shell to secure the shell to the flat surface. A third flange may also be included to secure the shell to the patient's chest wall. The shell includes a substantially rigid outer member and a relatively softer inner member that is in contact with the patient's breast when the device is in use. The substantially rigid outer member includes a suction port and the relatively softer inner member includes a through holes in fluid communication with the suction port, to allow a patient's breast to be drawn toward the inner member when fluid is drawn from the suction port. Imaging and interventional procedures may be carried out through the opening by making an incision in the superior portion of the peri-areolar border. Both surface and intra-tissue ultrasound may be utilized to localize the lesion and to provide real time imaging of the uncompressed and stabilized breast during the breast-stabilized biopsy or excisional procedure.
摘要翻译：用于成像和侵入性医疗程序的乳房稳定装置包括壳体，其构造成当乳房搁置在基本平坦的表面上时围绕乳房的上部。壳体包括构造成允许乳房的乳头 - 非极性复合体的至少一部分突出穿过其中的第一开口。第一和第二凸缘从壳体延伸以将壳体固定到平坦表面。还可以包括第三凸缘以将壳固定到患者的胸壁上。外壳包括基本刚性的外部构件和相对较软的内部构件，当该装置在使用中时，其与患者的乳房接触。基本刚性的外部构件包括吸入口，并且相对较软的内部构件包括与吸入口流体连通的通孔，以便当流体从吸入口抽出时允许患者的乳房被拉向内部构件。成像和介入手术可以通过开口进行，在周边边界的上部进行切口。可以利用表面和组织内超声来定位病变并且在乳房稳定的活检或切除手术期间提供未压缩和稳定的乳房的实时成像。

70. 发明授权

US6157852A Catheter apparatus for treating arterial occlusions 失效
标题翻译：用于治疗动脉闭塞的导管器械
公开(公告)号：US6157852A
公开(公告)日：2000-12-05
申请号：US8033
申请日：1998-01-16
申请人： Matthew R. Selmon , James W. Vetter , Tomoaki Hinohara , Charles F. Milo
发明人： Matthew R. Selmon , James W. Vetter , Tomoaki Hinohara , Charles F. Milo
IPC分类号： A61B8/12 , A61B17/00 , A61B17/22 , A61B17/30 , A61B17/32 , A61B19/00 , A61M25/01 , A61M29/02 , A61B5/00
CPC分类号： A61B17/3207 , A61B8/12 , A61B17/320725 , A61B17/320758 , A61B2017/00247 , A61B2017/00252 , A61B2017/22077 , A61B2017/308 , A61B2017/320004 , A61B2017/320044 , A61B2018/00392 , A61B2090/3784 , A61M2025/1097 , A61M25/0147
摘要： An apparatus is described for treating arterial occlusions combining an intraluminally operable catheter, having an occlusion-crossing working element, with a micro-invasive extraluminally operable locator for imaging the progress of the working element through the occlusion. Conical, abrasive, blunt-dissecting, and sharp-pointed, and steering and non-steering working elements including guide wires are described. Acoustic transducers and a flexible imaging tube are described for the locator. A suction cup is described for removably anchoring the imaging tube to a surface. A signal-emitting working element and cooperating signal-receiving locator are described. A method for treating arterial occlusions is described.
摘要翻译：描述了一种用于治疗动脉闭塞的装置，其组合具有阻塞交叉工作元件的可透光操作的导管与微创外向可操作的定位器，用于通过闭塞成像工作元件的进展。描述了包括导丝在内的锥形，磨料，钝性解剖和锋利的转向和非转向工作元件。描述了定位器的声学换能器和柔性成像管。描述了用于可移除地将成像管固定到表面的吸盘。描述信号发射工作元件和配合信号接收定位器。描述了治疗动脉闭塞的方法。

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