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61. 发明授权

US5794811A Carton, carton blank and method for forming the carton 失效
标题翻译：纸箱，纸箱和形成纸箱的方法
公开(公告)号：US5794811A
公开(公告)日：1998-08-18
申请号：US741342
申请日：1996-10-29
申请人： Joseph C. Walsh
发明人： Joseph C. Walsh
IPC分类号： B31B7/00 , B65D5/56
CPC分类号： B65D5/563 , B65D5/56 , B31B2217/0084
摘要： A carton blank for forming a leakproof carton comprising an outer enclosure formed from a relatively rigid material an openable top a closed bottom and a central body and a leakproof inner liner having a central body portion secured to the central body of the outer enclosure, a closed bottom and an openable closed top so that after portions of the material in the carton have been removed the top portion and adjacent portions of the inner liner's central body may be separated from the central body of the outer enclosure and folded downwardly to protect the remaining material in the carton. In one embodiment, after all the material has been removed from the carton, the leakproof inner liner may be completely removed from the outer enclosure.
摘要翻译：一种用于形成防漏纸箱的纸板坯，包括由相对刚性的材料形成的外壳，可打开的顶部，封闭的底部和中心体以及具有固定到外壳的中心主体的中心主体部分的防漏内衬;封闭的底部和可打开的封闭顶部，使得在纸箱中的部分材料已经被去除之后，内衬的中心体的顶部和相邻部分可以与外壳的中心体分离并向下折叠以保护剩余材料在纸箱里在一个实施例中，在从纸箱中取出所有材料之后，可以从外壳完全去除防漏内衬。

62. 发明授权

US5632402A Carton blank and method for forming it 失效
标题翻译：纸箱坯料及其成型方法
公开(公告)号：US5632402A
公开(公告)日：1997-05-27
申请号：US587753
申请日：1996-01-17
申请人： Joseph C. Walsh , Robert L. Conatser
发明人： Joseph C. Walsh , Robert L. Conatser
IPC分类号： B31B7/00 , B65D5/62 , B65D5/56
CPC分类号： B65D5/62 , B32B37/12 , B31B2217/0084 , Y10S493/907
摘要： A carton blank formed from a laminate of a relatively flexible fluid impervious material and a relatively rigid paperboard material is provided with paperboard to paperboard facing surfaces so that an effective seal can be formed.
摘要翻译：由相对柔性的不透液体材料和相对刚性的纸板材料的层压体形成的纸板坯料具有纸板到面向纸板的表面，从而可以形成有效的密封。

63. 发明授权

US08025618B2 Packages, blanks for making packages and associated methods and apparatus 有权
标题翻译：包装，制作包装的空白以及相关的方法和设备
公开(公告)号：US08025618B2
公开(公告)日：2011-09-27
申请号：US10318437
申请日：2002-12-13
申请人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
发明人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
IPC分类号： B31F1/00
CPC分类号： B65D5/563 , B31B2105/001 , B65D5/0281 , B65D5/4212 , B65D5/4266 , B65D5/441 , B65D5/5425 , B65D5/544 , B65D5/703 , B65D5/705 , B65D5/744 , B65D71/0022 , B65D2301/10 , B65D2571/00141 , B65D2571/00388 , B65D2571/00487 , B65D2571/00524 , B65D2571/0066 , B65D2571/00802 , B65D2571/00839 , B65D2571/00919 , B65D2571/00956
摘要： Disclosed herein, for example, are methods and apparatus for forming carton blanks. In one such method, a first web of material and a second web of material may be provided. At least one line of disruption may be formed in one of the webs of material. A combined section may be formed that includes a section of the first web of material and a section of the second web of material. Thereafter, a carton blank may be formed by separating the combined section from the first web of material and the second web of material. Also disclosed herein, for example, are various carton blanks and cartons.
摘要翻译：这里公开的是例如用于形成纸板坯的方法和装置。在一种这样的方法中，可以提供第一材料网和第二材料网。可以在一个材料网中形成至少一行破裂。可以形成组合部分，其包括第一材料卷材的一部分和第二材料卷材的一部分。此后，可以通过将组合的部分与第一材料纤维网和第二材料纤维网分开来形成纸板坯料。这里也公开了例如各种纸箱和纸箱。

64. 发明授权

US07717322B2 Packages, blanks for making packages and associated methods 有权
公开(公告)号：US07717322B2
公开(公告)日：2010-05-18
申请号：US11951633
申请日：2007-12-06
申请人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
发明人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
IPC分类号： B65D43/16
CPC分类号： B65D5/723 , B65D5/0281 , B65D5/16 , B65D5/46072 , B65D5/4802 , B65D5/5445 , B65D5/6608 , B65D5/6623
摘要： Cartons are formed from two or more continuous webs that can individually or concurrently provided with cuts, scores, or other lines of disruption.

65. 发明授权

US07658318B2 Packages, blanks for making packages and associated methods 有权
标题翻译：软件包，制作软件包的空白以及相关的方法
公开(公告)号：US07658318B2
公开(公告)日：2010-02-09
申请号：US11448620
申请日：2006-06-07
申请人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek , Kelly R. Fitzwater , Weston R. Wilson
发明人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek , Kelly R. Fitzwater , Weston R. Wilson
IPC分类号： B65D17/28 , B65D5/32
CPC分类号： B65D5/0281 , B31B70/00 , B31B2105/001 , B65D5/4212 , B65D5/4266 , B65D5/441 , B65D5/48002 , B65D5/5425 , B65D5/544 , B65D5/5445 , B65D5/563 , B65D5/703 , B65D5/705 , B65D5/744 , B65D71/0022 , B65D2301/10 , B65D2571/00141 , B65D2571/00388 , B65D2571/00487 , B65D2571/00524 , B65D2571/0066 , B65D2571/00802 , B65D2571/00839 , B65D2571/00919 , B65D2571/00956
摘要： Cartons are formed from two or more continuous webs that can individually or concurrently provided with cuts, scores, or other lines of disruption.
摘要翻译：纸箱由两个或更多个连续的纸幅形成，可以单独或同时地提供切割，分数或其他干扰线。

66. 发明授权

US07160537B2 Method for preparing radiolabeled thymidine having low chromophoric byproducts 有权
标题翻译：制备具有低发色副产物的放射性标记的胸苷的方法
公开(公告)号：US07160537B2
公开(公告)日：2007-01-09
申请号：US10736087
申请日：2003-12-15
申请人： Joseph C. Walsh , Henry C. Padgett , Tanea Ysaguirre
发明人： Joseph C. Walsh , Henry C. Padgett , Tanea Ysaguirre
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： A61K51/0491 , C07H19/048 , Y02P20/55
摘要： The invention is a method and related precursor for preparing 18F-FLT. The precursor has a butoxycarbonyl protecting group at the 5′-position that results in low amounts of chromophoric byproducts being formed during deprotection. The method for preparing 18F-FLT is efficient and makes the final purification step less complicated.
摘要翻译：本发明是一种用于制备F-FL-FLT的方法和相关前体。该前体在5'-位具有丁氧羰基保护基，导致在脱保护期间形成少量的发色副产物。制备 F-FLT的方法是有效的，并且使得最终的纯化步骤不那么复杂。

67. 发明授权

US07045361B2 Analyte sensing via acridine-based boronate biosensors 失效
标题翻译：通过基于吖啶的硼酸盐生物传感器进行分析物检测
公开(公告)号：US07045361B2
公开(公告)日：2006-05-16
申请号：US09952563
申请日：2001-09-12
申请人： Aaron M. Heiss , Joseph C. Walsh , David J. Vachon , Glenn Noronha , Jonathan Reilly , Bill C. Ponder , William P. Van Antwerp
发明人： Aaron M. Heiss , Joseph C. Walsh , David J. Vachon , Glenn Noronha , Jonathan Reilly , Bill C. Ponder , William P. Van Antwerp
IPC分类号： G01N21/64 , G01N33/58 , G01N33/66
CPC分类号： G01N33/66 , C12Q1/54 , Y10T436/144444
摘要： Fluorescent biosensor molecules, fluorescent biosensors and systems, as well as methods of making and using these biosensor molecules and systems are described. These biosensor molecules address the problem of obtaining fluorescence emission at wavelengths greater than about 500 nm. Biosensor molecules generally include an (1) an acridine-based fluorophore, (2) a linker moiety and (3) a boronate substrate recognition/binding moiety, which binds polyhydroxylate analytes, such as glucose. These biosensor molecules further include a “switch” element that is drawn from the electronic interactions among these submolecular components. This fluorescent switch is generally “off” in the absence of bound polyhydroxylate analyte and is generally “on” in the presence of bound polyhydroxylate analyte. Thus, the reversible binding of a polyhydroxylate analyte essentially turns the fluorescent switch “on” and “off”. This property of the biosensor molecules, as well as their ability to emit fluorescent light at greater than about 500 nm, renders these biosensor molecules particularly well-suited for detecting and measuring in-vivo glucose concentrations.
摘要翻译：描述荧光生物传感器分子，荧光生物传感器和系统，以及制造和使用这些生物传感器分子和系统的方法。这些生物传感器分子解决了在大于约500nm的波长处获得荧光发射的问题。生物传感器分子通常包括（1）基于吖啶的荧光团，（2）接头部分和（3）结合多羟基化合物分析物如葡萄糖的硼酸酯底物识别/结合部分。这些生物传感器分子还包括从这些亚分子组分之间的电子相互作用中抽出的“开关”元件。在不存在结合的多羟基甲酸盐分析物的情况下，该荧光开关通常是“关闭”的，并且在结合的多羟基化合物分析物的存在下通常是“开”的。因此，多羟基化合物分析物的可逆结合基本上使得荧光开关“开”和“关”。生物传感器分子的这种性质以及它们在大于约500nm处发射荧光的能力使得这些生物传感器分子特别适用于检测和测量体内葡萄糖浓度。

68. 发明授权

US07022872B2 Method for making fluorine labeled L-Dopa 有权
标题翻译：制备氟标记的L-多巴的方法
公开(公告)号：US07022872B2
公开(公告)日：2006-04-04
申请号：US10742023
申请日：2003-12-19
申请人： Joseph C. Walsh , Henry C. Padgett
发明人： Joseph C. Walsh , Henry C. Padgett
IPC分类号： C07C229/36 , C07C271/22
CPC分类号： C07C271/22 , C07B2200/05 , C07B2200/07 , C07C227/32 , C07C229/36 , C07C269/06
摘要： The invention relates to a method for preparing F-Dopa and 18F-Dopa and intermediates that are useful in the method. The invention is a method that synthesizes F-Dopa and 18F-Dopa in good yield with high enantiopurity without the need for further transformations. The method includes the step of reacting a benzaldehyde derivative with a phosphonic acid derivative to produces an olefin intermediate that can be asymmetrically hydrogenated to produce the desired enantiomer.
摘要翻译：本发明涉及一种制备在该方法中有用的F-多巴和十八氟多卡因和中间体的方法。本发明是以高的对映体纯度合成F-Dopa和16 F-多巴的方法，而不需要进一步的转化。该方法包括使苯甲醛衍生物与膦酸衍生物反应以产生不对称氢化以产生所需对映异构体的烯烃中间体的步骤。

69. 发明授权

US06689034B2 Transfer glue system and method for a right angle gluing machine 失效
标题翻译：转角胶机系统及方法
公开(公告)号：US06689034B2
公开(公告)日：2004-02-10
申请号：US09877336
申请日：2001-06-08
申请人： Joseph C. Walsh , Kenneth E. Hawkins
发明人： Joseph C. Walsh , Kenneth E. Hawkins
IPC分类号： B31B162
CPC分类号： B31B50/00 , B31B50/624 , B31B50/81 , B31B2105/00 , B31B2120/20 , B31B2241/001 , Y10T156/1798
摘要： Disclosed herein is a method and apparatus for applying adhesive to packaging in a variety of configurations. The adhesive may be applied by a nozzle in a first direction, a second direction and a stationary spot, wherein the first direction and the second direction are transverse to each other.
摘要翻译：本文公开了一种用于以各种构造将粘合剂施加到包装的方法和装置。粘合剂可以通过喷嘴在第一方向，第二方向和静止点处施加，其中第一方向和第二方向彼此横向。

70. 发明授权

US06386438B1 Carton blank, carton and method of forming the carton 有权
标题翻译：纸箱，纸箱和成型纸箱的方法
公开(公告)号：US06386438B1
公开(公告)日：2002-05-14
申请号：US09607197
申请日：2000-06-28
申请人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
发明人： Joseph C. Walsh , Robert L. Conatser , Raymond S. Kastanek
IPC分类号： B65D300
CPC分类号： B65D5/6623
摘要： A carton blank having an outer layer of a relatively rigid material, a first inner layer of a relatively rigid material superposed over a portion of the outer layer and a second inner layer of a relatively flexible layer of a fluid impervious material is provided with first and second weakened portions so that, after a carton has been formed from the carton blank, filled with a desired material and sealed, the first weakened portion may be broken to form a flip top lid which when moved in an arcuate path will gradually sever the second weakened portion to form an opening in the carton so that an amount of the desired material may be removed from the carton.
摘要翻译：一种具有相对刚性材料的外层的纸板坯料，叠置在外层的一部分上的相对刚性材料的第一内层和不透液体材料的相对柔性层的第二内层设置有第一和第二弱化部分，使得在从纸箱坯件形成纸箱之后填充所需材料并密封，第一弱化部分可能被破坏以形成翻盖，当在弓形路径中移动时将逐渐地切断第二弱化部分弱化部分以在纸箱中形成开口，使得可以从纸箱中取出所需材料的量。

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