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61. 发明授权

US06627632B2 Compositions and methods for the treatment of anorectal disorders 失效
标题翻译：用于治疗肛门直肠疾病的组合物和方法
公开(公告)号：US06627632B2
公开(公告)日：2003-09-30
申请号：US09919590
申请日：2001-07-30
申请人： Thomas P. Parks , Vivien Mak , Jung-Chung Lee , Charles Lee
发明人： Thomas P. Parks , Vivien Mak , Jung-Chung Lee , Charles Lee
IPC分类号： A61K3150
CPC分类号： A61K9/0031 , A61K31/198 , A61K31/21 , A61K31/505 , A61K31/513 , A61K31/519 , A61K31/52 , A61K31/522
摘要： Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2−) scavengers, &bgr;-adrenergic agonists, cAMP-dependent protein kinase activators, &agr;1-adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive K+ channel activators and smooth muscle relaxants are used.
摘要翻译：提供了用于治疗肛门直肠疾病的组合物和方法，其中NO供体，PDE抑制剂，超氧化物（O 2 - ）清除剂，β-肾上腺素能激动剂，cAMP依赖性蛋白激酶激活剂，α1-肾上腺素能拮抗剂，类型的Ca 2+通道阻滞剂，雌激素，ATP敏感性K +通道激活剂和平滑肌松弛剂。

62. 发明授权

US06623013B1 Seal device 失效
标题翻译：密封装置
公开(公告)号：US06623013B1
公开(公告)日：2003-09-23
申请号：US09719063
申请日：2001-02-02
申请人： Charles Lee
发明人： Charles Lee
IPC分类号： F16J1510
CPC分类号： F16J15/027 , B65D90/626 , B65D2590/542 , B65G69/183
摘要： According to the invention there is provided a seal device (1), for example for use with an obturating device such as a cone value (2) of an intermediate bulk container (3) (IBC) which is set down at a discharge station (4) with a sealing arrangement therebetween so that when a lifting member such as a cone (5) of the discharge station (4) is operated to raise the cone valve (2) and open a flow path for flowable material such as a powder from the IBC through the discharge station (4). In order to provide a seal, the seal device (1) of an elastomeric material, has an annular seal surface (6) and means (7) which enhances sealing by the sealing surface (6).
摘要翻译：根据本发明，提供了一种密封装置（1），例如用于诸如中间散装容器（3）（IBC）的锥形值（2）的密封装置，其放置在放电站（ 4），其间具有密封装置，使得当诸如排放站（4）的锥体（5）的提升构件被操作以升高锥形阀（2）并且打开用于可流动材料如粉末的流动路径 IBC通过放电站（4）。为了提供密封，弹性体材料的密封装置（1）具有环形密封表面（6）和增强密封表面（6）的密封的装置（7）。

63. 发明授权

US06622258B1 Data protection in a ring network 失效
标题翻译：环网中的数据保护
公开(公告)号：US06622258B1
公开(公告)日：2003-09-16
申请号：US09546035
申请日：2000-04-10
申请人： Charles Lee , Ray Paradiso , Jonathan Morgan
发明人： Charles Lee , Ray Paradiso , Jonathan Morgan
IPC分类号： G06F1100
CPC分类号： H04L12/437 , H04J2203/0042 , H04J2203/006
摘要： A method for reconfiguring a ring of nodes connected by a working fiber and a protection fiber upon disruption of the signal in either the working fiber or the protection fiber includes signaling the other nodes. Each node determines whether it is a node adjacent to the disruption. Those nodes that are not adjacent to the disruption undergo no change in their operation. A receiving node adjacent to the disruption forms a bridge isolating the disruption and sends an acknowledgement signal back to a signaling node. Upon receipt of the acknowledgement signal, the signaling node also forms a bridge. This results in the isolation of that portion of the ring having a disruption and the formation of a new ring.
摘要翻译：在工作光纤或保护光纤中的信号中断时，重新配置由工作光纤和保护光纤连接的节点环的方法包括发信号通知其他节点。每个节点确定它是否是与中断相邻的节点。与中断不相邻的那些节点不会改变其运行。与中断相邻的接收节点形成隔离中断的桥，并将确认信号发送回信令节点。在接收到确认信号时，信令节点也形成桥。这导致环的该部分的分离具有破坏并形成新的环。

64. 发明授权

US06463825B2 Brake turntable for actuating a brake system for a walker 失效
标题翻译：用于驱动步行器制动系统的制动转盘
公开(公告)号：US06463825B2
公开(公告)日：2002-10-15
申请号：US10012544
申请日：2001-12-12
申请人： Charles Lee
发明人： Charles Lee
IPC分类号： E16C112
CPC分类号： B60T1/005 , A61H3/04 , A61H2003/046 , B62L3/08 , F16D49/00 , F16D63/006 , F16D2121/16 , F16D2125/60 , Y10T74/2042
摘要： A brake mechanism for a walker, essentially comprised of a brake disk with toothed peripheral is provided on the side of the wheel, a brake base allows relative displacement, and toothed section on the inner side of the brake base, wherein, said brake base as pushed by an elastic member holds with its toothed section against the toothed peripheral of the brake disk to brake the wheel in normal status, a handle is used to manipulate a brake cable to pull the brake base so to release the brake; furthermore, a turning block in the shape of a turntable is provided to accommodate the same brake cable connecting both brake handle, the turning block is further connected to another two brake cables to synchronously activate the brake mechanisms for the RH and the LH wheels; by pulling either brake handle, the synchronous release or brake of both brake mechanism can be achieved while allowing a 2-step brake.
摘要翻译：用于步行器的制动机构，主要由具有齿形周边的制动盘组成，其制动器底座允许相对移动，并且制动器底座内侧的齿形部分，其中，所述制动器底座为由弹性构件推动，其齿形部分抵靠制动盘的齿形周边保持正常状态，手柄用于操纵制动缆索以拉动制动器基座以释放制动器; 此外，提供转台形状的转动块以容纳连接两个制动手柄的相同的制动电缆，转动块进一步连接到另外两个制动电缆，以同步地激活用于RH和LH轮的制动机构; 通过拉动制动手柄，可以实现两个制动机构的同步释放或制动，同时允许两步制动。

65. 发明授权

US06395736B1 Compositions and methods for the treatment of anorectal disorders 失效
标题翻译：用于治疗肛门直肠疾病的组合物和方法
公开(公告)号：US06395736B1
公开(公告)日：2002-05-28
申请号：US09460306
申请日：1999-12-13
申请人： Thomas P. Parks , Vivien Mak , Jung-Chung Lee , Charles Lee
发明人： Thomas P. Parks , Vivien Mak , Jung-Chung Lee , Charles Lee
IPC分类号： A61K3150
CPC分类号： A61K31/21 , A61K31/198 , A61K31/505 , A61K31/52
摘要： Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2−) scavengers, &bgr;-adrenergic agonists, cAMP-dependent protein kinase activators, &agr;1-adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive K+ channel activators and smooth muscle relaxants are used.
摘要翻译：提供了治疗肛门直肠疾病的组合物和方法，其中NO供体，PDE抑制剂，超氧化物（O 2 - ）清除剂，β-肾上腺素能激动剂，cAMP依赖性蛋白激酶激活剂，α1-肾上腺素能拮抗剂，L型Ca2 + 使用通道阻滞剂，雌激素，ATP敏感性K +通道激活剂和平滑肌松弛剂。

66. 外观设计

USD362956S Shoe insole 失效
公开(公告)号：USD362956S
公开(公告)日：1995-10-10
申请号：US20299
申请日：1994-03-23
申请人： Jack L. Martin , Charles Lee
设计人： Jack L. Martin , Charles Lee

67. 发明申请

US20190391651A1 FLEXIBLE AND TACTILE PRESSURE SENSITIVE SWITCH SENSORS 审中-公开
公开(公告)号：US20190391651A1
公开(公告)日：2019-12-26
申请号：US16447878
申请日：2019-06-20
申请人： Sartaj Chowdhury , Katherine Rodríguez Hernández , Hugo Umaña Vindas , Mateusz Mittek , Abrar Chowdhury , Charles Lee
发明人： Sartaj Chowdhury , Katherine Rodríguez Hernández , Hugo Umaña Vindas , Mateusz Mittek , Abrar Chowdhury , Charles Lee
IPC分类号： G06F3/01 , G01L1/18
摘要： Described herein is a flexible piezoresistive switch sensor responding only to a minimum threshold compression deformation force. The switch sensor comprises a non-porous housing that separates an external environment from an internal environment; one or more decoupled electrodes comprising or formed of a flexible conductor; a non conductive insulating spacer layer enforcing the one or more decoupled electrodes in bending or twisting forces, while allowing electrode coupling due to compression; a piezoresistive layer decoupled from the electrodes via the insulating spacer layer; and an elastomeric polymer layer comprising one or more buckling or spring elements configured to separate a minimum required compression force on the piezoresistive layer and the non-conductive insulating layer.

68. 发明授权

US09064115B2 Malware detection system and method for limited access mobile platforms 有权
标题翻译：用于有限访问移动平台的恶意软件检测系统和方法
公开(公告)号：US09064115B2
公开(公告)日：2015-06-23
申请号：US11697664
申请日：2007-04-06
申请人： George Tuvell , Charles Lee
发明人： George Tuvell , Charles Lee
IPC分类号： H04L29/00 , G06F21/56 , H04L29/06 , H04W12/12 , H04W12/10
CPC分类号： G06F21/566 , G06F17/30424 , G06F21/56 , G06F21/562 , G06F21/563 , G06F21/564 , G06F21/565 , G06F2221/033 , H04L63/1441 , H04L63/145 , H04W12/10 , H04W12/12
摘要： A system and method for detecting malware on a limited access mobile platform in a mobile network. The system and method uses one or more feature sets that describe various non-executable portions of malware-infected and malware-free applications, and compares a application on the limited access mobile platform to the features sets. A match of the features in a suspect application to one of the feature sets provides an indication as to whether the suspect application is malware-infected or malware-free.
摘要翻译：一种用于在移动网络中的有限接入移动平台上检测恶意软件的系统和方法。系统和方法使用描述恶意软件感染和无恶意软件应用程序的各种不可执行部分的一个或多个特征集，并将有限接入移动平台上的应用与特征集进行比较。将可疑应用程序中的功能与其中一个功能集的匹配提供了可疑应用程序是否受到恶意软件感染或无恶意软件的指示。

69. 发明申请

US20150024406A1 INCREASED AQUAPORIN EXPRESSION ON CELLULAR MEMBRANE TO IMPROVE CRYOPRESERVATION EFFICIENCY 审中-公开
标题翻译：增加细胞膜上的水合蛋白表达以提高克隆效率
公开(公告)号：US20150024406A1
公开(公告)日：2015-01-22
申请号：US14330738
申请日：2014-07-14
申请人： Robin N. Coger-Simmons , Laura Whritenour Schrum , Balasubramanian Karthik Kumar , Charles Lee
发明人： Robin N. Coger-Simmons , Laura Whritenour Schrum , Balasubramanian Karthik Kumar , Charles Lee
IPC分类号： A01N1/02 , G01N33/50 , C12N5/071
CPC分类号： A01N1/0221 , C12N5/067 , G01N33/5067
摘要： A method of storing mammalian cells or tissue (e.g., liver cells or hepatocytes) for subsequent use comprises the steps of: (a) contacting the cells or tissue in vitro to a choleretic agent in an effective amount; (b) combining said cells or tissue with a cryopreservative; (c) freezing said cells or tissue, and then (d) storing said frozen cells or tissue in frozen form for subsequent use.
摘要翻译：存储用于随后使用的哺乳动物细胞或组织（例如肝细胞或肝细胞）的方法包括以下步骤：（a）将细胞或组织体外接触有效量的胆汁剂; （b）将所述细胞或组织与冷冻保存剂组合; （c）冷冻所述细胞或组织，然后（d）将所述冷冻的细胞或组织以冷冻形式储存以供后续使用。

70. 发明授权

US08919704B2 Conduit hanger and support apparatus 有权
标题翻译：管道衣架和支撑装置
公开(公告)号：US08919704B2
公开(公告)日：2014-12-30
申请号：US13748656
申请日：2013-01-24
申请人： Charles Lee , Elio Evangelista , Paul Burke
发明人： Charles Lee , Elio Evangelista , Paul Burke
IPC分类号： F16L3/08 , F16L3/26
CPC分类号： F16L3/26 , F16L3/11 , H02G3/263 , Y10T29/49
摘要： A support assembly for supporting a conduit includes a support, a clamp, and a hanger. The support has a partial-cylindrical shape including a first section having a first diameter and a second section having a second diameter that is greater than the first diameter. In one aspect, at least one of the first section and the second section define a first aperture in the partial-cylindrical shape. In another aspect, at least one of the first section and the second section includes a retention member extending radially from an outer surface of the partial-cylindrical shape. The retention member includes a closed loop or a partially-open loop that defines a second aperture for receiving a strap to secure the conduit to the support. The clamp is configured to secure the conduit to the support. The hanger is configured to suspend the support from a structure.
摘要翻译：用于支撑导管的支撑组件包括支撑件，夹具和悬挂器。支撑件具有部分圆柱形形状，其包括具有第一直径的第一部分和具有大于第一直径的第二直径的第二部分。在一个方面，第一部分和第二部分中的至少一个限定了部分圆柱形形状的第一孔。在另一方面，第一部分和第二部分中的至少一个包括从部分圆柱形形状的外表面径向延伸的保持部件。保持构件包括闭环或部分开放的环，其限定用于接收带以将导管固定到支撑件的第二孔。夹具被配置成将导管固定到支撑件上。吊架构造成将结构悬挂在支架上。

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