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    • 68. 发明授权
    • Nanoparticle structures utilizing synthetic DNA lattices
    • 利用合成DNA晶格的纳米颗粒结构
    • US06673401B2
    • 2004-01-06
    • US09733968
    • 2000-12-12
    • Charles T. BlackStephen M. GatesChristopher B. MurrayShouheng Sun
    • Charles T. BlackStephen M. GatesChristopher B. MurrayShouheng Sun
    • B32B1102
    • B82Y25/00C07B2200/01C12N15/10C40B40/00H01F1/0054H01F1/0063Y10T428/13Y10T428/24331Y10T428/249978Y10T428/249979Y10T428/24999Y10T428/32
    • A laminar structure upon a substrate is formed from a) a lattice layer comprising DNA (deoxyribonucleic acid) segments arranged to form cells of the lattice layer, and b), at least one nanoparticle being disposed within each cell of the lattice layer. The nanoparticles are preferably of substantially uniform diameter not exceeding 50 nanometers. A coating may be applied to adhere the the particles to the substrate and to maintain their substantially uniform spaced-apart relationship. The DNA lattice layer is fabricated using known automated synthetis methods, and is designed to contain specific nucleotide base sequences which cause the DNA to form an ordered array of openings, or lattice cells, by self-assembly. Self-assembly of the DNA lattice may be at an air-liquid interface, or in solution. A preferred embodiment is a magnetic storage medium in which the particles are magnetic particles with diameters in the range of 5-20 nm., the particles being organized in square information bits with each bit holding of 4, 9, 16, 25 etc. particles to produce areal information storage densities on the order of 1000 gigabits (one terabit) per square inch. The lattice of bits may be stabilized and protected by a deposited thin film, hard, abrasion-resistant coating.
    • 基底上的层状结构由a)由布置成形成晶格层的单元的DNA(脱氧核糖核酸)区的晶格层形成,以及b)至少一个纳米颗粒设置在晶格层的每个单元内。 纳米颗粒优选具有不超过50纳米的基本均匀的直径。 可以施加涂层以将颗粒附着到基材上并保持其基本均匀的间隔关系。 使用已知的自动化合成方法制造DNA晶格层,并且被设计为含有特定的核苷酸碱基序列,其通过自组装使DNA形成有序的开口阵列或晶格细胞。 DNA晶格的自组装可以在空气 - 液体界面处或在溶液中。 优选的实施方案是磁性存储介质,其中颗粒是直径在5-20nm范围内的磁性颗粒,颗粒被组织成平方信息位,每个位保持4,9,16,25等颗粒 以产生大约1000吉比特(1兆比特)每平方英寸的面积信息存储密度。 位的晶格可以被沉积的薄膜,硬的耐磨涂层稳定和保护。
    • 69. 发明授权
    • Nanoparticle structures utilizing synthetic DNA lattices
    • 利用合成DNA晶格的纳米颗粒结构
    • US06265021B1
    • 2001-07-24
    • US09127452
    • 1998-07-31
    • Charles T. BlackStephen M. GatesChristopher B. MurrayShouheng Sun
    • Charles T. BlackStephen M. GatesChristopher B. MurrayShouheng Sun
    • B32B1100
    • B82Y25/00C07B2200/01C12N15/10C40B40/00H01F1/0054H01F1/0063Y10T428/13Y10T428/24331Y10T428/249978Y10T428/249979Y10T428/24999Y10T428/32
    • A laminar structure upon a substrate is formed from a) a lattice layer comprising DNA (deoxyribonucleic acid) segments arranged to form cells of the lattice layer, and b), at least one nanoparticle being disposed within each cell of the lattice layer. The nanoparticles are preferably of substantially uniform diameter not exceeding 50 nanometers. A coating may be applied to adhere the particles to the substrate and to maintain their substantially uniform spaced-apart relationship. The DNA lattice layer is fabricated using known automated synthetis methods, and is designed to contain specific nucleotide base sequences which cause the DNA to form an ordered array of openings, or lattice cells, by self-assembly. Self-assembly of the DNA lattice may be at an air-liquid interface, or in solution. A preferred embodiment is a magnetic storage medium in which the particles are magnetic particles with diameters in the range of 5-20 nm., the particles being organized in square information bits with each bit holding of 4, 9, 16, 25 etc. particles to produce real information storage densities on the order of 1000 gigabits (one terabit) per square inch. The lattice of bits may be stabilized and protected by a deposited thin film, hard, abrasion-resistant coating.
    • 基底上的层状结构由a)由布置成形成晶格层的单元的DNA(脱氧核糖核酸)区的晶格层形成,以及b)至少一个纳米颗粒设置在晶格层的每个单元内。 纳米颗粒优选具有不超过50纳米的基本均匀的直径。 可以施加涂层以将颗粒附着到基底上并保持其基本均匀的间隔关系。 使用已知的自动化合成方法制造DNA晶格层,并且被设计为含有特定的核苷酸碱基序列,其通过自组装使DNA形成有序的开口阵列或晶格细胞。 DNA晶格的自组装可以在空气 - 液体界面处或在溶液中。 优选的实施方案是磁性存储介质,其中颗粒是直径在5-20nm范围内的磁性颗粒,颗粒被组织成平方信息位,每个位保持4,9,16,25等颗粒 以产生大约1000吉比特(1兆比特)每平方英寸的真实信息存储密度。 位的晶格可以被沉积的薄膜,硬的耐磨涂层稳定和保护。