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61. 发明申请

US20070055136A1 Inspection apparatus using magnetic resonance 审中-公开
标题翻译：使用磁共振的检查装置
公开(公告)号：US20070055136A1
公开(公告)日：2007-03-08
申请号：US11471708
申请日：2006-06-21
申请人： Yukari Yamamoto , Atsushi Maki
发明人： Yukari Yamamoto , Atsushi Maki
IPC分类号： A61B5/05
CPC分类号： G01R33/48 , A61B5/055 , A61B5/417 , A61B5/4509
摘要： A means to predict bone density reduction before it actually begins will be provided. This invention provides a method to detect abnormalities in the bone marrow hemopoietic cells which precede the bone density reduction, by obtaining a nuclear magnetic resonance image containing a flat bone or an a long bone epiphysis, and evaluating the signal intensity in the red marrow area.
摘要翻译：将提供在实际开始之前预测骨密度降低的手段。本发明提供一种检测骨密度降低前的骨髓造血细胞异常的方法，通过获得含有平骨或长骨骨ysis的核磁共振图像，评价红髓区域的信号强度。

62. 发明申请

US20070038154A1 Living body inspection apparatus 有权
标题翻译：生活检查仪器
公开(公告)号：US20070038154A1
公开(公告)日：2007-02-15
申请号：US11455191
申请日：2006-06-19
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Kuniomi Ogata , Atsushi Maki , Daisuke Suzuki
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Kuniomi Ogata , Atsushi Maki , Daisuke Suzuki
IPC分类号： A61B5/103 , A61B5/117
CPC分类号： A61B5/1125 , A61B5/1126 , A61B5/6825 , A61B5/6826 , A61B5/6838
摘要： A living body inspection apparatus which quantitatively evaluates timings of movements (bending and stretching) of fingers. The apparatus includes: a movement sensor including a transmitter coil for generating a magnetic field and a plurality of receiver coils for receiving the generated magnetic field from the transmitter coil; analyzing means which analyzes time-series waveform data acquired from the movement sensor; and display means which displays a result of analysis made by the analyzing means. For comparison of waveform data, the analyzing means includes distance waveform generating means for generating distance waveforms corresponding to the waveform data, and standard point generating means for generating standard points based on standard distances in the distance waveforms.
摘要翻译：生物体检查装置，其定量地评价手指的移动（弯曲和伸展）的定时。该装置包括：运动传感器，包括用于产生磁场的发射器线圈和用于从发射器线圈接收所产生的磁场的多个接收器线圈; 分析装置，其分析从所述运动传感器获取的时间序列波形数据; 以及显示装置，显示由分析装置进行的分析结果。为了比较波形数据，分析装置包括用于产生与波形数据对应的距离波形的距离波形发生装置，以及用于根据距离波形中的标准距离产生标准点的标准点产生装置。

63. 发明申请

US20070038067A1 Living body inspection apparatus 审中-公开
标题翻译：生活检查仪器
公开(公告)号：US20070038067A1
公开(公告)日：2007-02-15
申请号：US11480518
申请日：2006-07-05
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Kuniomi Ogata , Atsushi Maki
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Kuniomi Ogata , Atsushi Maki
IPC分类号： A61B5/05
CPC分类号： A61B5/04005 , A61B5/1124 , A61B5/1126 , A61B5/6826 , G01R33/0354
摘要： Living body inspection apparatus which concurrently carries out proper measurement of movement of a living body and measurement of a magnetic field emanating from the living body. It includes a movement sensor which includes magnetic field generating means for generating a magnetic field and magnetic field receiving means attached to a living body for receiving the magnetic field and measures movement of the living body based on the magnetic field emitted from the magnetic field generating means and received by the magnetic field receiving means. It also includes: a SQUID magnetometer which receives a biomagnetic field emanating from the living body; analyzing means which analyzes measurement data obtained by the movement sensor and the SQUID magnetometer; and display means which outputs a result of analysis made by the analyzing means. The magnetic field generating means is fixed in a prescribed position relative to the SQUID magnetometer.
摘要翻译：生物体检查装置同时进行生物体的运动的适当的测量以及从生物体发出的磁场的测量。其包括运动传感器，其包括用于产生磁场的磁场产生装置和附接到生物体的磁场接收装置，用于接收磁场，并且基于从磁场产生装置发射的磁场来测量活体的运动并由磁场接收装置接收。它还包括：SQUID磁力计，其接收从生物体发出的生物磁场; 分析装置，分析由运动传感器和SQUID磁力计获得的测量数据; 以及显示装置，其输出由分析装置进行的分析结果。磁场产生装置相对于SQUID磁力计固定在规定位置。

64. 发明申请

US20060100525A1 Biological optical measurement system 有权
公开(公告)号：US20060100525A1
公开(公告)日：2006-05-11
申请号：US11205160
申请日：2005-08-17
申请人： Takusige Katura , Naoki Tanaka , Hiroki Sato , Akiko Obata , Atsushi Maki
发明人： Takusige Katura , Naoki Tanaka , Hiroki Sato , Akiko Obata , Atsushi Maki
IPC分类号： A61B6/00
CPC分类号： A61B5/6814 , A61B5/0059 , A61B5/024 , A61B5/14553
摘要： A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.

65. 发明授权

US07022083B2 Measurement system for living bodies 失效
标题翻译：活体测量系统
公开(公告)号：US07022083B2
公开(公告)日：2006-04-04
申请号：US10457478
申请日：2003-06-10
申请人： Naoki Tanaka , Atsushi Maki , Masashi Kiguchi
发明人： Naoki Tanaka , Atsushi Maki , Masashi Kiguchi
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/486 , A61B5/0086 , A61B5/1455
摘要： A satisfactory averaged signal can be obtained with only a small number of repetitions of measurement in the measurement of responses to a stimulus given to a living body. A low-frequency biological fluctuation is extracted and a stimulus is presented to the living body in synchronism with the phase of the extracted fluctuation.
摘要翻译：在对给予生物体的刺激的响应的测量的测量中，可以仅获得少量的测量重复来获得满意的平均信号。提取低频生物波动，并且与提取的波动的相位同步地向生物体提供刺激。

66. 发明申请

US20050192490A1 Living body light measurement system and signal processing method 失效
标题翻译：生活体光测量系统及信号处理方法
公开(公告)号：US20050192490A1
公开(公告)日：2005-09-01
申请号：US11010668
申请日：2004-12-14
申请人： Tsuyoshi Yamamoto , Atsushi Maki , Takusige Katura , Hideo Kawaguchi
发明人： Tsuyoshi Yamamoto , Atsushi Maki , Takusige Katura , Hideo Kawaguchi
IPC分类号： G01N21/17 , A61B5/00 , A61B10/00
CPC分类号： A61B5/14553 , A61B5/0042 , A61B2562/0233 , A61B2562/046
摘要： An image generating methodology for displaying brain activation areas with improved accuracy in a living body light measurement system for generating an image of the changes in blood volume of the brain. A spatial intensity distribution of changes in blood volume can be generated by detecting brain activation in many sampling points, and a spatial interpolation process is executed on this data. A threshold process is executed on the distribution to extract the distribution of coordinates having a signal intensity of at least the predetermined threshold. The displacement between the brain activation area and the maximal location of the distribution is stored in a recording unit of the system in order to compensate for the distribution extracted by the threshold process. Accordingly, brain activation areas can be estimated with greater location accuracy, and the diagnosis and medial treatment for brain diseases can likewise be executed with greater accuracy.
摘要翻译：一种用于在生物体光测量系统中显示脑激活区域以提高准确度的图像产生方法，用于产生脑的血容量变化的图像。通过检测许多采样点的大脑激活，可以产生血容量变化的空间强度分布，并对该数据执行空间插值处理。对分布执行阈值处理以提取具有至少预定阈值的信号强度的坐标的分布。大脑激活区域和分布的最大位置之间的位移被存储在系统的记录单元中，以便补偿由阈值处理提取的分布。因此，可以以更高的定位精度估计脑激活区域，并且同样可以更准确地执行脑疾病的诊断和内侧治疗。

67. 发明授权

US08311600B2 Optical measurement instrument for living body 有权
标题翻译：生物体光学测量仪器
公开(公告)号：US08311600B2
公开(公告)日：2012-11-13
申请号：US11954627
申请日：2007-12-12
申请人： Takusige Katura , Naoki Tanaka , Atsushi Maki
发明人： Takusige Katura , Naoki Tanaka , Atsushi Maki
IPC分类号： A61B5/1455
CPC分类号： A61B5/0059 , A61B5/02028 , A61B5/6814 , A61B5/7207 , G06K9/6243
摘要： An optical measurement instrument for living body includes: a plurality of light irradiation means for irradiating an object being tested with light; a plurality of light reception means for detecting the light that is irradiated to the object being tested and propagates inside the object being tested; and a calculation unit for calculating hemodynamics of a plurality of factors inside the object being tested from the detection signal detected by the light reception means, wherein the calculation unit includes a separation calculation unit for separating a plurality of signals from the detection signals; a selection unit for calculating a correlation coefficient between a plurality of the signals separated to select a signal in which a correlation coefficient is a predetermined value or greater as a noise signal; and a reconstruction calculation unit for reconfiguring the detection signal excluding the noise signal selected by the selection unit.
摘要翻译：一种用于生物体的光学测量仪器包括：多个光照射装置，用于用光照射被测物体; 多个光接收装置，用于检测照射到被测试物体上的光并在待测物体的内部传播; 以及计算单元，用于根据由光接收装置检测的检测信号计算被测物体内的多个因子的血液动力学，其中所述计算单元包括分离计算单元，用于从所述检测信号中分离出多个信号; 选择单元，用于计算分离以选择其中相关系数为预定值或更大的信号的多个信号之间的相关系数作为噪声信号; 以及重建计算单元，用于重新配置除了由选择单元选择的噪声信号之外的检测信号。

68. 发明授权

US07991447B2 Biological photometric equipment 有权
标题翻译：生物测光设备
公开(公告)号：US07991447B2
公开(公告)日：2011-08-02
申请号：US10577944
申请日：2004-07-01
申请人： Hiroki Sato , Masashi Kiguchi , Atsushi Maki , Tsuyoshi Yamamoto
发明人： Hiroki Sato , Masashi Kiguchi , Atsushi Maki , Tsuyoshi Yamamoto
IPC分类号： A61B5/1455
CPC分类号： A61B5/14553
摘要： To control information obtained from inside of a living body with higher precision as compared to that in the conventional technology by controlling a ratio of intensities of light, directed to a trial body, in a plurality of wavelength ranges different in peak wavelength from each other, a measurement error included in information obtained from the living body can be controlled by changing a ratio of intensity of the light in the first wavelength range against that of the light in the second wavelength range. When intensity of irradiated light is limited from the viewpoint of safety to the trial subject, keeping a ratio of the light irradiated to the trial body in the first wavelength range against that of the light in the second wavelength range under a prespecified value and also changing the ratio of irradiated light intensities under the prespecified value.
摘要翻译：通过在峰值波长不同的多个波长范围内控制指向试验体的光的强度比，通过控制比现有技术更高的精度从内部获得的生物体的信息，可以通过改变第一波长范围内的光的强度与第二波长范围内的光的强度的比例来控制从生物体获得的信息中包括的测量误差。当照射光的强度从安全性的角度受限于试验对象时，将照射在试验体上的光的第1波长范围内的光与第2波长范围内的光的比例保持在规定值以下，照射光强度的比例在预先指定的值之下。

69. 发明授权

US07613502B2 Optical bioinstrumentation for living body 有权
标题翻译：活体光生物仪器
公开(公告)号：US07613502B2
公开(公告)日：2009-11-03
申请号：US11205184
申请日：2005-08-17
申请人： Yukari Yamamoto , Atsushi Maki , Masashi Kiguchi , Tsuyoshi Yamamoto
发明人： Yukari Yamamoto , Atsushi Maki , Masashi Kiguchi , Tsuyoshi Yamamoto
IPC分类号： A61B5/00
CPC分类号： A61B5/14553 , A61B5/0042 , A61B5/064 , A61B5/6814 , A61B5/7425 , A61B5/743 , A61B34/20 , A61B2034/2051 , A61B2034/2055 , A61B2034/2063
摘要： In a probe positioning technology, an optical bioinstrumentation includes a region selecting unit that is used to delineate a region of interest in an anatomical image of a subject, a computing unit that determines a recommended probe position according to the region of interest, a probe position sensor that detects a current probe position, a computing unit that calculates the distance between the recommended probe position and the current probe position, and an alarm device that generates an alarm sound or the like when the distance falls within a predetermined range. Moreover, the optical bioinstrumentation for living body further includes a memory unit in which the probe position is saved together with measurement data.
摘要翻译：在探针定位技术中，光学生物仪器包括区域选择单元，其用于描绘对象的解剖图像中的感兴趣区域，计算单元，其根据感兴趣的区域确定推荐的探针位置，探针位置检测当前探头位置的传感器，计算推荐探测位置与当前探测位置之间的距离的计算单元，以及当距离在预定范围内时产生报警声等的报警装置。此外，生物体的光学生物仪器还包括存储单元，其中探测位置与测量数据一起被保存。

70. 发明授权

US07565192B2 Biological optical measurement system 有权
标题翻译：生物光学测量系统
公开(公告)号：US07565192B2
公开(公告)日：2009-07-21
申请号：US11205160
申请日：2005-08-17
申请人： Takusige Katura , Naoki Tanaka , Hiroki Sato , Akiko Obata , Atsushi Maki
发明人： Takusige Katura , Naoki Tanaka , Hiroki Sato , Akiko Obata , Atsushi Maki
IPC分类号： A61B5/00
CPC分类号： A61B5/6814 , A61B5/0059 , A61B5/024 , A61B5/14553
摘要： A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.
摘要翻译：分配给测量大脑活动信号的典型任务持续10到30秒。梅耶尔波噪声信号的频带非常接近脑活动信号的频带，结果是难以使用带通滤波器或带通滤波器来减少梅耶波噪声信号。提供了用于检测已经通过或反射在组织内的发射光的光照射单元和光检测单元。生物信号测量单元测量脉动，呼吸，血压和温度中的至少一个。由光检测单元获得的光信号与使用非线性分析的生物信号之间的关系; 以及基于所获得的关系从生物噪声信号与光信号分离的计算。

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