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61. 发明专利

AU2011200584B2 Ophthalmic compositions and methods for treating ophthalmic conditions 未知
公开(公告)号：AU2011200584B2
公开(公告)日：2013-05-30
申请号：AU2011200584
申请日：2011-02-11
申请人： ALLERGAN INC
发明人： WHITCUP SCOTT M
IPC分类号： A61K31/573 , A61K9/10 , A61K47/30 , A61P27/02
摘要： C:\NRorb\C TXS\464348_1.DOC-IOA)2/2011 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS Abstract Compositions, and methods of using such compositions, useful for placement, for example injection, into the interior of human or animal eyes are provided. Such compositions include a therapeutic component, such as one or more corticosteroids, a biocompatible polymeric component, and a solvent component. The composition is in a fluid foiin before 10 placement in the interior of an eye, and becomes less fluid after the composition is placed in the eye to form an extended or delayed release drug delivery element or system. The drug delivery element is foiiued by the dissipation of the solvent from the composition when the composition is placed in the interior of an eye. One example of a composition includes triamcinolone acetonide as a therapeutic agent. A method of treating an 15 ophthalmic condition, or otherwise improving or enhancing vision of a patient, comprises placing the fluid composition in the interior of the eye. The method may be practiced by injecting the fluid composition into the interior of the eye.

62. 发明专利

MX2013001866A AGONISTAS DE RECEPTOR DE PROSTAGLANDINA SUPTIPO-2(EP2) O RECEPTOR DE PROSTAGLANDINA SUPTIPO-4(EP4) PARA TRATAR LA OPACIDAD DE LA CORNEA 未知
公开(公告)号：MX2013001866A
公开(公告)日：2013-05-22
申请号：MX2013001866
申请日：2011-08-17
申请人： ALLERGAN INC
发明人： WHEELER LARRY A , WHITCUP SCOTT M , IM WHA BIN , JIANG GUANG-LIANG
IPC分类号： A61K31/559 , A61P27/02
摘要： En la presente se describen composiciones y métodos para tratar la opacidad de la córnea Las composiciones y métodos de uso comprenden cantidades terapéuticamente efectivas de los compuestos que agoniza el receptor de EP2 y/o de EP4 La administración de los compuestos descritos puede prevenir y tratar el desarrollo de la opacidad de la cornea

63. 发明专利

CL2013000484A1 Metodo de tratamiento de opacidad corneal en un ojo que comprende la administracion de una composicion farmaceutica que comprende un compuesto seleccionado de un agonista ep2 y un agonista ep4 y una combinacion de los mismos. 未知
公开(公告)号：CL2013000484A1
公开(公告)日：2013-05-10
申请号：CL2013000484
申请日：2013-02-18
申请人： ALLERGAN INC
发明人： JIANG GUANG-LIANG , IM WHA BIN , WHEELER LARRY A , WHITCUP SCOTT M
IPC分类号： A61K31/559 , A61P27/02
摘要： Método de tratamiento de opacidad corneal en un ojo que comprende la administración de una composición farmacéutica que comprende un compuesto seleccionado de un agonista EP2 y un agonista EP4 y una combinación de los mismos.

64. 发明专利

CA2853054A1 THERMORESPONSIVE COMPOSITIONS FOR DERMATOLOGICAL USE AND METHODS THEREOF 未知
公开(公告)号：CA2853054A1
公开(公告)日：2013-04-25
申请号：CA2853054
申请日：2012-10-17
申请人： ALLERGAN INC
发明人： WHITCUP SCOTT M , OLEJNIK OREST
IPC分类号： A61L27/16 , A61L27/18 , A61L27/52
摘要： The present specification generally relates to compositions comprising a thermoresponsive polymer and methods of treating a soft tissue condition using such compositions.

65. 发明专利

AU2011282549A1 Compounds and methods for skin repair 未知
公开(公告)号：AU2011282549A1
公开(公告)日：2013-02-28
申请号：AU2011282549
申请日：2011-07-29
申请人： ALLERGAN INC
发明人： JIANG GUANG L , BURK ROBERT M , IM WHA BIN , BEDDINGFIELD FREDERICK C , WHEELER LARRY A , WHITCUP SCOTT M
IPC分类号： A61K8/42 , A61K8/49 , A61K9/00 , A61K31/167 , A61K31/343 , A61K31/381 , A61K31/4015 , A61K31/421 , A61K31/519 , A61P17/02 , A61Q19/08
摘要： The disclosure provides compositions and methods for treating a skin blemish. The compositions comprise a therapeutically effective amount of a compound useful for treating skin blemishes such as wounds, scars and wrinkles.

66. 发明专利

AU2013200020A1 Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid 未知
公开(公告)号：AU2013200020A1
公开(公告)日：2013-01-24
申请号：AU2013200020
申请日：2013-01-03
申请人： ALLERGAN INC
发明人： BURKE JAMES A , OLEJNIK OREST , HUGHES PATRICK M , WHITCUP SCOTT M
IPC分类号： A61K9/00 , A61K9/10 , A61K9/14 , A61K31/00 , A61K47/36
摘要： C:\NRPortbl\DCC\TXS\31654731. DOC-3/09/2010 COMPOSITIONS FOR LOCALIZED THERAPY OF THE EYE, COMPRISING PREFERABLY TRIAMCINOLONE ACETONIDE AND HYALURONIC ACID Abstract Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that 10 facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, 15 and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.

67. 发明专利

ZA201104746B COMPOSITIONS FOR ENHANCING NAIL GROWTH 未知
公开(公告)号：ZA201104746B
公开(公告)日：2012-03-28
申请号：ZA201104746
申请日：2011-06-27
申请人： ALLERGAN INC
发明人： MULLINS DEBBIE , STUCKER CONNIE , WHITCUP SCOTT M , SCHIFFMAN RHETT M , WALT JOHN G
IPC分类号： A61K20060101 , A61P20060101
摘要： The present invention is directed to compositions and methods for stimulating the growth of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to increase nail growth and thicken, strengthen and smooth the nail. The composition is also effective in strengthening and growing nails, including fingernails and toenails.

68. 发明专利

ZA201104745B CYCLOSPORINE COMPOSITIONS FOR ENHANCING NAIL GROWTH 未知
公开(公告)号：ZA201104745B
公开(公告)日：2012-03-28
申请号：ZA201104745
申请日：2011-06-27
申请人： ALLERGAN INC
发明人： MULLINS DEBBIE , STUCKER CONNIE , WHITCUP SCOTT M , SCHIFFMAN RHETT M , WALT JOHN G
IPC分类号： A61K20060101 , A61P20060101 , A61Q20060101
摘要： The present invention is directed to compositions and methods for stimulating the growth of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to increase nail growth and thicken, strengthen and smooth the nail. The composition is also effective in strengthening and growing nails, including fingernails and toenails.

69. 发明专利

AU2010241513B2 Use of brimonidine for preventing and reducing the severity of stress-associated conditions 未知
公开(公告)号：AU2010241513B2
公开(公告)日：2011-09-22
申请号：AU2010241513
申请日：2010-11-18
申请人： ALLERGAN INC
发明人： GIL DANIEL W , DONELLO JOHN E , BRIN MITCHELL F , WHITCUP SCOTT M
IPC分类号： A61K31/498 , A61P25/00
摘要： C .NRPorb\DCC\TXS%3311552_1 DOC-17/111/2010 USE OF BRIMONIDINE FOR PREVENTING AND REDUCING THE SEVERITY OF STRESS-ASSOCIATED CONDITIONS Abstract The present invention provides a method of preventing or reducing the severity of a stress associated condition in a subject by systemically administering to the subject an effective amount of brimonidine or a pharmaceutically acceptable salt, ester, amide, sterioisomer or racemic mixture thereof. Stress-associated conditions that can be treated according to a 10 method of the invention include, but are not limited to, dyspepsia, tachycardias other than tachycardia associated with myocardial ischemia, panic attack, non-inflammatory dermatogical conditions, disorders of muscle contraction, sensory hypersensitivity associated with migraine, and behavioral disorders.

70. 发明专利

AU2008207547B2 Using selective antagonists of persistent sodium current to treat neurological disorders and pain 未知
公开(公告)号：AU2008207547B2
公开(公告)日：2011-08-11
申请号：AU2008207547
申请日：2008-08-27
申请人： ALLERGAN INC
发明人： GEORGE EHRING , ADORANTE JOSEPH S , DONELLO JOHN E , THOMAS MALONE , WHEELER LARRY A , WHITCUP SCOTT M
IPC分类号： A61K31/00 , A61K31/13 , A61K31/136 , A61K31/235 , A61K31/381 , A61K31/433 , A61K31/4439 , A61P25/02 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/24 , A61P25/28 , A61P25/30 , A61P29/02
摘要： P:\WPDOCS\CRN\RMH \Spccil n abstrado.27/08/2008 USING SELECTIVE ANTAGONISTS OF PERSISTENT SODIUM CURRENT TO TREAT NEUROLOGICAL DISORDERS AND PAIN The present invention provides uses of compounds as medicaments for treating neurological disorders and chronic pain in mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20 fold selectivity for persistent sodium current relative to transient sodium current.

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