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    • 63. 发明授权
    • Orthovoltage radiotherapy
    • 电磁放电
    • US07697663B2
    • 2010-04-13
    • US12023968
    • 2008-01-31
    • Michael Gertner
    • Michael Gertner
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 描述了放射外科系统,其将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中,治疗炎症性眼部疾病,特别是黄斑变性。 在一些实施例中,眼睛结构被放置在基于眼睛成像的全局坐标系中,其导致自动定位系统的方向。 在一些实施例中,追踪眼结构的位置并与放射外科系统有关。 在一些实施方案中,治疗计划用于待治疗的特定疾病和/或要避免的结构。 在一些实施例中,基准有助于定位系统。 在一些实施例中,使用眼睛的反射来帮助定位。 在一些实施例中,描述了放射外科手术与其他治疗组合使用的放射治疗疗法,并且可以在其它治疗之前,之前或之后进行递送。
    • 64. 发明授权
    • Orthovoltage radiotherapy
    • 电磁放电
    • US07680245B2
    • 2010-03-16
    • US12023954
    • 2008-01-31
    • Michael Gertner
    • Michael Gertner
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system. In some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system. In some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial is placed on the eye to aid in positioning. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 描述了放射外科系统,其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中,治疗炎症性眼部疾病,特别是黄斑变性。 在一些实施例中,将眼部结构置于基于眼睛成像的全局坐标系中。 在一些实施例中,全局坐标系内的目镜结构导致基于坐标系内的眼睛结构而被引导的自动定位系统的方向。 在一些实施例中,跟踪眼结构的位置并且与放射外科手术系统的状态相关。 在一些实施例中,使用治疗计划,其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施例中,结构是眼睛,并且眼睛被系统跟踪。 在一些实施例中,眼睛被保持就位,并且在一些实施例中,眼睛被患者固定。 在一些实施例中,将基准置于眼睛上以帮助定位。 在一些实施例中,使用眼睛的反射来帮助定位。 在一些实施例中,描述了放射外科手术与其他治疗组合使用的放射治疗疗法,并且可以在其它治疗之前,之前或之后进行递送。
    • 65. 发明授权
    • Ocular radiosurgery
    • 眼放射外科
    • US07680244B2
    • 2010-03-16
    • US11873386
    • 2007-10-16
    • Michael GertnerErik ChellSteven D. HansenMark ArnoldussenMatt HerronKuang-Hung Pan
    • Michael GertnerErik ChellSteven D. HansenMark ArnoldussenMatt HerronKuang-Hung Pan
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 描述了放射外科系统,其将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中,治疗炎症性眼部疾病,特别是黄斑变性。 在一些实施例中,眼睛结构被放置在基于眼睛成像的全局坐标系中,其导致自动定位系统的方向。 在一些实施例中,追踪眼结构的位置并与放射外科系统有关。 在一些实施方案中,治疗计划用于待治疗的特定疾病和/或要避免的结构。 在一些实施例中,基准有助于定位系统。 在一些实施例中,使用眼睛的反射来帮助定位。 在一些实施例中,描述了放射外科手术与其他治疗组合使用的放射治疗疗法,并且可以在其它治疗之前,之前或之后进行递送。
    • 66. 发明授权
    • Hemodialysis access with on-off functionality
    • 血液透析进入开关功能
    • US07588551B2
    • 2009-09-15
    • US11734186
    • 2007-04-11
    • Michael Gertner
    • Michael Gertner
    • A61M5/00
    • A61M1/36A61F2/06A61M1/16A61M1/3653A61M1/3655A61M1/3659A61M1/3661A61M1/3672A61M1/3673
    • A treatment assembly is positioned along an AV-fistula and couples therapeutic energy to an adjacent area due to a material response to an applied energy field from a remotely located energy source. The treatment assembly may be delivered into the fistula through a hemodialysis needle, or may be secured to the fistula graft itself and implanted therewith within a patient. A cover provides a shield between an anastomosis area and blood flow. Another AV-fistula includes a valved reservoir that receives a fluid agent from a hemodialysis needle while moving the needle into or from the fistula; the agent leaks from the reservoir into the fistula lumen. Another valved fistula is adjustable between an open condition and closed conditions during and between hemodialysis treatments, respectively. Another AV-fistula has a bladder reservoir coupled to a second refillable fluid reservoir and is adapted to locally deliver a therapeutic agent into the fistula lumen.
    • 治疗组件沿着AV瘘定位并且将治疗能量耦合到相邻区域,这是由于对来自远程位置的能源的施加的能量场的材料响应。 治疗组件可以通过血液透析针递送到瘘管中,或者可以固定到瘘移植物本身并且将其植入患者体内。 盖子在吻合区域和血液流动之间提供屏蔽。 另一个AV-瘘包括一个带有阀的储存器,它从血液透析针接收流体药剂,同时将针头移入或移出瘘管; 药剂从储存器泄漏到瘘管腔中。 血液透析治疗期间和之间的另外一个阀门瘘可以在开放状态和关闭状态之间调节。 另一个AV瘘具有联接到第二可再填充流体储存器的膀胱储存器并且适于将治疗剂局部输送到瘘管腔中。
    • 68. 发明申请
    • ORTHOVOLTAGE RADIOTHERAPY
    • US20080187100A1
    • 2008-08-07
    • US12023905
    • 2008-01-31
    • Michael Gertner
    • Michael Gertner
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system. In some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system. In some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial is placed on the eye to aid in positioning. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 69. 发明申请
    • ORTHOVOLTAGE RADIOTHERAPY
    • US20080181362A1
    • 2008-07-31
    • US12023954
    • 2008-01-31
    • Michael Gertner
    • Michael Gertner
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system. In some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system. In some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial is placed on the eye to aid in positioning. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 70. 发明申请
    • Devices With Integral Magnets and Uses Thereof
    • 具有集成磁铁及其用途的设备
    • US20080140100A1
    • 2008-06-12
    • US11424226
    • 2006-06-14
    • Michael Gertner
    • Michael Gertner
    • A61B17/22
    • A61B17/22A61B17/22004A61B2017/003A61B2017/00876
    • In one embodiment, an elongate body with a proximal end and a distal end is disclosed and which is controllable by an operator at the proximal end; in one embodiment, the elongate body is a catheter and the catheter tip is located at the distal end. The body contains numerous magnets along its length, at least one of which is an electromagnet, controllable by means of a current delivered by the operator of the body at the proximal end of the body. The magnets are placed such that a force is created at the distal end of the elongate body. The magnetic forces which control the distal end of the body originate from the controllable magnets placed on the body.
    • 在一个实施例中,公开了具有近端和远端的细长主体,并且其可由近端的操作者控制; 在一个实施例中,细长主体是导管,并且导管尖端位于远端。 身体沿其长度包含许多磁体,其中至少一个是电磁体,可通过身体操作者在身体的近端传递的电流来控制。 磁体被放置成使得在细长体的远端产生力。 控制身体远端的磁力源于放置在身体上的可控磁体。