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61. 发明申请

WO2008022265A3 PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES 审中-公开
标题翻译：植物ISOFLAVONE和ISOFLAVANONE O-甲基转移酶基因
公开(公告)号：WO2008022265A3
公开(公告)日：2008-07-24
申请号：PCT/US2007076113
申请日：2007-08-16
申请人： SAMUEL ROBERTS NOBLE FOUND INC , DEAVOURS BETTINA E , LIU CHANG-JUN , NOEL JOSEPH P , DIXON RICHARD A
发明人： DEAVOURS BETTINA E , LIU CHANG-JUN , NOEL JOSEPH P , DIXON RICHARD A
IPC分类号： C12N9/10 , A23L19/00 , C07D311/36 , C12N15/29 , C12N15/54 , C12N15/82
CPC分类号： C12N9/1007 , C12N15/8243 , C12N15/8279
摘要： The invention provides enzymes that encode O-methyltransferases (OMTs) from Medicago truncatula that allow modification to plant (iso)flavonoid biosynthetic pathways. In certain aspects of the invention, the genes encoding these enzymes are provided. The invention therefore allows the modification of plants for isoflavonoid content. Transgenic plants comprising such enzymes are also provided, as well as methods for improving disease resistance in plants. Methods for producing food and nutraceuticals, and the resulting compositions, are also provided.
摘要翻译：本发明提供了编码来自Medicago truncatula的O-methyltransferases（OMT）的酶，其允许修饰植物（异）类黄酮生物合成途径。在本发明的某些方面，提供了编码这些酶的基因。因此，本发明允许植物修饰异黄酮含量。还提供了包含这些酶的转基因植物，以及用于改善植物中抗病性的方法。还提供了生产食品和营养品的方法以及所得组合物。

62. 发明申请

WO2008054476A3 ELECTROSTATIC NANOLITHOGRAPHY PROBE ACTUATION DEVICE AND METHOD 审中-公开
公开(公告)号：WO2008054476A3
公开(公告)日：2008-05-08
申请号：PCT/US2007/006374
申请日：2007-03-14
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , LIU, Chang , BULLEN, David, Andrew
发明人： LIU, Chang , BULLEN, David, Andrew
IPC分类号： G12B21/00
摘要： Method and apparatus for selectively actuating a cantilevered probe for applying a compound to a substrate in nanolithography. A probe having a probe electrode and a substrate having a counter electrode are provided. Voltage applied to the probe electrode and/or counter electrode provides electrostatic attraction between them, moving a probe tip into sufficient proximity to the substrate to apply the patterning compound. Alternatively, a flexible cantilevered probe anchored to a holder includes a layer of conductive material forming a probe electrode. A counter electrode on the holder faces the probe electrode. The holder and probe are positioned so that a probe tip applies the compound to the substrate. The probe is disposed between the substrate and the counter electrode. An electrostatic attractive force generated between the probe electrode and the counter electrode flexes the probe and lifts the tip away from the substrate to suspend writing.

63. 发明申请

WO2007126738A2 LIMITED CURRENT CIRCUIT FOR ELECTRO-LUMINESCENT LAMP INVERTER 审中-公开
标题翻译：电子灯泡逆变器的有限电流
公开(公告)号：WO2007126738A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/007416
申请日：2007-03-26
申请人： CEELITE LLC , LIANG, Chin-Ping , LIU, Chang-Yi , WU, En-Ming
发明人： LIANG, Chin-Ping , LIU, Chang-Yi , WU, En-Ming
IPC分类号： G09G3/10
CPC分类号： H05B33/08 , Y02B20/32
摘要： A current limiting device includes a constant current source circuit (12) constructed and arranged to be connected to a direct current input voltage source and to regulate electrical current and a resonance source circuit (14) receiving current from the constant current source circuit. The resonance source circuit is constructed and arranged to be electrically connected with an electro-luminescent (EL) lamp (28) so that the EL lamp receives alternating current. The constant current source circuit and the resonance source circuit are constructed and arranged such that when current flows from the constant current source circuit to the resonance source circuit and to the EL lamp, a maximum peak current received by a user contacting an output of the device or contacting the EL lamp is less than about 0.7 mA.
摘要翻译：限流装置包括构造和布置成连接到直流输入电压源并调节电流的恒流源电路（12），以及从恒流源电路接收电流的谐振源电路（14）。谐振源电路被构造和布置成与电致发光（EL）灯（28）电连接，使得EL灯接收交流电。恒流源电路和谐振源电路被构造和布置成使得当电流从恒流源电路流到谐振源电路和EL灯时，由用户接收到的器件的输出接收到的最大峰值电流或接触EL灯小于约0.7mA。

64. 发明申请

WO2005114673A1 SCANNING PROBE MICROSCOPE PROBE WITH INTEGRATED CAPILLARY CHANNEL 审中-公开
标题翻译：扫描探头微波探头与集成毛细通道
公开(公告)号：WO2005114673A1
公开(公告)日：2005-12-01
申请号：PCT/US2005/013929
申请日：2005-04-22
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , LIU, Chang
发明人： LIU, Chang
IPC分类号： G12B21/02
CPC分类号： G01Q70/16 , B82B3/00 , G01Q70/10 , G03F7/0002
摘要： A scanning probe microscope probe is disclosed. The scanning probe microscope probe includes a handle and a cantilever shank connected with the handle. The cantilever shank has at one end a base connected with the handle and at an opposing end a tip. The cantilever shank forms a capillary channel between the base to the tip of the cantilever shank.
摘要翻译：公开了扫描探针显微镜探针。扫描探针显微镜探针包括手柄和与把手连接的悬臂。悬臂在一端具有与把手连接的底座，在相对的端部具有尖端。悬臂在基部与悬臂的尖端之间形成毛细通道。

65. 发明申请

WO2004103886A2 MICROFABRICATED MICRO FLUID CHANNELS 审中-公开
标题翻译：微流化微流体通道
公开(公告)号：WO2004103886A2
公开(公告)日：2004-12-02
申请号：PCT/US2004/013974
申请日：2004-05-05
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , LIU, Chang , RYU, Kee , BULLEN, David
发明人： LIU, Chang , RYU, Kee , BULLEN, David
IPC分类号： B67D
CPC分类号： B01L3/0241 , B01J2219/00369 , B01L2200/12 , B01L2300/0819 , B01L2300/0838 , B01L2300/0887 , B01L2400/0406 , B01L2400/0487 , C40B60/14 , Y10T137/0318
摘要： A fluid delivery system including a first substrate having a micro-channel and a well both formed through the first substrate. The fluid delivery system also includes a second substrate and a delivery channel - The second substrate is on the first substrate and he delivery channel is formed between the first and second substrates. The delivery channel provides fluid communication between the micro-channel and the well.
摘要翻译：一种流体输送系统，包括具有微通道的第一基底和通过第一基底形成的孔。流体输送系统还包括第二基底和输送通道。第二基底位于第一基底上，并且输送通道形成在第一和第二基底之间。输送通道提供微通道和井之间的流体连通。

66. 发明申请

WO2023010342A1 INTRINSICALLY SAFE CIRCUIT FOR LOAD 审中-公开
公开(公告)号：WO2023010342A1
公开(公告)日：2023-02-09
申请号：PCT/CN2021/110601
申请日：2021-08-04
申请人： ABB SCHWEIZ AG , BALUJA, Wilfred Fernando , LIU, Chang , YU, Yasong
发明人： BALUJA, Wilfred Fernando , LIU, Chang , YU, Yasong
IPC分类号： H02H9/04 , H02M7/04
摘要： Embodiments of present disclosure relate to an intrinsically safe circuit for a load. The intrinsically safe circuit comprises an input adapted to be connected to a power supply; an output adapted to be connected to the load; a switching unit connected between the input and the output and configured to deliver an energy from the input to the output; a voltage clamping unit connected to the input and the switching unit, and configured to turn off the switching unit when an input voltage at the input exceeds a threshold voltage and clamp the input voltage to the threshold voltage, and configured to limit a leakage current through the voltage clamping unit below a predetermined leakage current level when the input voltage is in the vicinity of the threshold voltage; and a current limiting unit connected between the switching unit and the output and configured to limit a current to the output so as to limit the energy delivered to the output.

67. 发明申请

WO2023010324A1 INTRINSICALLY SAFE CIRCUIT FOR LOAD 审中-公开
公开(公告)号：WO2023010324A1
公开(公告)日：2023-02-09
申请号：PCT/CN2021/110495
申请日：2021-08-04
申请人： ABB SCHWEIZ AG , BALUJA, Wilfred Fernando , LIU, Chang
发明人： BALUJA, Wilfred Fernando , LIU, Chang
IPC分类号： H02H9/00 , G01F23/00
摘要： Embodiments of present disclosure relate to an intrinsically safe circuit for a load. The intrinsically safe circuit comprises energy input ports and energy output ports; a first power line and a second power line connected in parallel between the energy input ports and energy output ports and configured to deliver energy from the energy input ports to the energy output ports; signal input ports and signal output ports; a first signal line and a second signal line connected in parallel between the signal input ports and signal output ports and configured to deliver signals between the signal input ports and signal output ports; a voltage clamping unit connected between the first power line, the second power line, the first signal line and the second signal line and configured to clamp a voltage between any two of the first power line, the second power line, the first signal line and the second signal line; and a current limiting unit connected in at least three of the first power line, the second power line, the first signal line and the second signal line, and configured to limit currents flowing through the first power line, the second power line, the first signal line and the second signal line.

68. 发明申请

WO2018165459A1 METHOD FOR HIGHLY SENSITIVE DNA METHYLATION ANALYSIS 审中-公开
公开(公告)号：WO2018165459A1
公开(公告)日：2018-09-13
申请号：PCT/US2018/021591
申请日：2018-03-08
申请人： THE UNIVERSITY OF CHICAGO , LIU, Chang , CUI, Xiaolong
发明人： LIU, Chang , CUI, Xiaolong , HE, Chuan , NERKHEDE, Pradnya , ZHAO, Boxuan
IPC分类号： C07H21/04 , C12P19/34 , C12Q1/68 , G01N33/50 , G01N33/574
摘要： Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used.

69. 发明申请

WO2010011398A4 SCANNING PROBE EPITAXY 审中-公开
标题翻译：扫描探针外延
公开(公告)号：WO2010011398A4
公开(公告)日：2010-07-29
申请号：PCT/US2009043866
申请日：2009-05-13
申请人： UNIV NORTHWESTERN , NANOINK INC , MIRKIN CHAD A , LIU CHANG , WANG YUHUANG , BRAUNSCHWEIG ADAM B , LIAO XING , GIAM LOUISE R , LEE BYUNG YANG , FRAGALA JOSEPH S , HENNING ALBERT K
发明人： MIRKIN CHAD A , LIU CHANG , WANG YUHUANG , BRAUNSCHWEIG ADAM B , LIAO XING , GIAM LOUISE R , LEE BYUNG YANG , FRAGALA JOSEPH S , HENNING ALBERT K
IPC分类号： G03F7/00 , G01Q70/10
CPC分类号： G03F7/0002 , G01Q20/04 , G01Q40/00 , G01Q70/10 , G01Q70/16 , G01Q80/00
摘要： A dual tip probe for scanning probe epitaxy is disclosed. The dual tip probe includes first and second tips disposed on a cantilever arm. The first and second tips can be a reader tip and a synthesis tip, respectively. The dual tip probe further includes a rib disposed on the cantilever arm between the first and second tips. The dual tip probe can also include a strain gauge disposed along the length of the cantilever arm.
摘要翻译：公开了一种用于扫描探针外延的双尖探针。双头探针包括设置在悬臂上的第一和第二尖端。第一和第二尖端可以分别是阅读器尖端和合成尖端。双头探针还包括设置在第一和第二尖端之间的悬臂上的肋。双头探针还可以包括沿着悬臂长度布置的应变计。

70. 发明申请

WO2010011397A4 SCANNING PROBE EPITAXY 审中-公开
公开(公告)号：WO2010011397A4
公开(公告)日：2010-01-28
申请号：PCT/US2009/043864
申请日：2009-05-13
申请人： NORTHWESTERN UNIVERSITY , MIRKIN, Chad, A. , LIU, Chang , WANG, Yuhuang , BRAUNSCHWEIG, Adam, B. , LIAO, Xing , GIAM, Louise, R. , LEE, Byung, Yang
发明人： MIRKIN, Chad, A. , LIU, Chang , WANG, Yuhuang , BRAUNSCHWEIG, Adam, B. , LIAO, Xing , GIAM, Louise, R. , LEE, Byung, Yang
IPC分类号： G01Q70/10 , G03F7/00
摘要： A dual tip probe for scanning probe epitaxy and a method of forming the dual tip probe are disclosed. The dual tip probe includes first and second tips disposed on a cantilever arm. The first and second tips can be a reader tip and a synthesis tip, respectively. The first tip can remain in contact with a substrate during writing and provide in situ characterization of the substrate and or structures written, while the second tip can perform in non-contact mode to write and synthesis nanostructures. This feature can allow the dual tip probe to detect errors in a printed pattern using the first tip and correct the errors using the second tip.

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