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61. 发明授权

US4297920A Cycloidic gear 失效
标题翻译：循环齿轮
公开(公告)号：US4297920A
公开(公告)日：1981-11-03
申请号：US55131
申请日：1979-07-05
申请人： Hans Richter
发明人： Hans Richter
IPC分类号： F16H1/32 , B25J9/10 , F16H1/28 , F16H35/00
CPC分类号： B25J9/103 , B25J9/1045 , F16H1/32 , Y10T74/1954
摘要： A cycloid gear is provided which comprises a pair of eccentric discs which are attached to a drive shaft and which carry curved discs thereon having outer peripheries of cyclodic curved shape which roll off along a plurality of rollers that engage said outer peripheries, the pair of curved discs having bore holes extending therethrough in overlapping relation to one another respectively to define an effective axially directed opening through each pair of overlapping bore holes, there being a plurality of axially directed bolts which pass through said effective axially directed openings and which are connected to an output shaft to drive the output shaft as the curved discs rotate with rotation of the drive shaft and eccentric discs. Each bolt carries a resilient roller whose unstressed outside diameter is greater than the predetermined minimum dimension of the effective axially directed opening with which said bolt is associated, whereby said rollers transmit the rotational movement of the curved discs to the output shaft without any clearance and preload the gear.
摘要翻译：提供了一种摆线齿轮，其包括一对偏心盘，其连接到驱动轴上并且在其上带有弯曲盘，其上具有环形弯曲形状的外周，所述外周弯曲形状沿着与所述外周接合的多个辊滚动，所述一对弯曲具有穿过其中彼此重叠的孔的孔的盘分别限定通过每对重叠的钻孔的有效的轴向定向的开口，存在多个轴向指向的螺栓，其穿过所述有效的轴向指向的开口并连接到输出轴驱动输出轴，因为弯曲盘随着驱动轴和偏心盘的旋转而旋转。每个螺栓承载弹性辊，其不受应力的外径大于与所述螺栓相关联的有效轴向开口的预定最小尺寸，由此所述辊将弯曲盘的旋转运动传递到输出轴，而没有任何间隙和预加载齿轮

62. 发明授权

US4245783A Condensation steam trap comprising a plate-like bimetal body having a curved stape 失效
标题翻译：冷凝式蒸汽疏水阀包括具有曲线状的板状双金属体
公开(公告)号：US4245783A
公开(公告)日：1981-01-20
申请号：US36298
申请日：1979-05-07
申请人： Hans Richter
发明人： Hans Richter
IPC分类号： F16T1/08
CPC分类号： F16T1/08
摘要： The condensation steam trap device includes a housing having a passage through the wall, which provides for fluid flow between the interior and exterior of the housing. The passage has a valve seat and carries a valve for engagement with the seat. A valve-actuating, temperature-sensitive element is disposed within the housing and has a connection with the valve for controlling the opening and closing thereof in response to changes in temperature of the element. The element is a bimetallic band or strip of curved or part-cylindrical shape. A nozzle or inlet pipe projects through another portion of the housing wall as well as through a clearance opening in the strip, the axis of the pipe and the discharge end thereof being directed against the inner surface of the strip substantially tagentially thereof. Condensate flowing through such pipe thus impinges a substantial area of the curved bimetallic strip causing the latter to move in response to a temperature change to a greater extent than would be true by directing such flow radially against the exterior of the strip. Upon actuation of the strip in response to temperature changes the valve in the aforesaid passage is also moved thereby controlling the degree of opening and closing thereof.
摘要翻译：冷凝蒸汽疏水装置包括具有通过壁的通道的壳体，其提供在壳体的内部和外部之间的流体流动。该通道具有阀座并承载用于与座接合的阀。阀门致动温度敏感元件设置在壳体内并且具有与阀的连接，用于响应于元件的温度变化来控制其开启和关闭。该元件是弯曲或部分圆柱形的双金属带或条带。喷嘴或入口管突出通过壳体壁的另一部分以及通过条带中的间隙开口，管的轴线和其排出端基本上以其标签方式被引导到带的内表面。流过这种管的冷凝物因此撞击弯曲的双金属带的大部分区域，导致后者响应于温度变化而比通过将这种流径向径向地引导到条的外部更大程度地移动。在响应于温度变化的条带致动时，上述通道中的阀也被移动，从而控制其开启和关闭的程度。

63. 发明授权

US4188386A Compositions containing thiocyanic acid and hexamethylene-tetramine, production process and administration thereof as bactericide and mycocide 失效
标题翻译：含有硫氰酸和六亚甲基四胺的组合物，其制备方法和作为杀菌剂和杀真菌剂
公开(公告)号：US4188386A
公开(公告)日：1980-02-12
申请号：US849262
申请日：1977-11-07
申请人： Robert Engl , Hans Richter
发明人： Robert Engl , Hans Richter
IPC分类号： A61K31/53
CPC分类号： A61K31/53
摘要： Disclosed herein is a process for producing dry compositions containing thiocyanic acid and hexamethylene-tetramine wherein hexamethylene-tetramine is reacted with an alkali or alkaline earth metal thiocyanate in the aqueous phase in the presence of acid, and wherein the aqueous reaction product solution, without isolation of the reaction product, is combined with an inert carrier substance and dried.
摘要翻译：本文公开了一种生产含有硫氰酸和六亚甲基 - 四胺的干组合物的方法，其中六亚甲基四胺在酸存在下在水相中与碱金属或碱土金属硫氰酸盐反应，并且其中不含离子的水反应产物溶液的反应产物与惰性载体物质组合并干燥。

64. 发明授权

US3034277A Device for crimping synthetic filaments 失效
标题翻译：压接合成纤维的装置
公开(公告)号：US3034277A
公开(公告)日：1962-05-15
申请号：US68468957
申请日：1957-09-18
申请人： HANS RICHTER
发明人： HANS RICHTER
IPC分类号： D02G1/06
CPC分类号： D02G1/06

65. 发明授权

US08765730B2 1-hydroxyimino-3-phenyl-propanes 有权
标题翻译： 1-羟基亚氨基-3-苯基 - 丙烷
公开(公告)号：US08765730B2
公开(公告)日：2014-07-01
申请号：US13180574
申请日：2011-07-12
申请人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
IPC分类号： A61K31/4409 , C07D401/10
CPC分类号： C07C251/48 , C07C2601/02 , C07C2601/14 , C07D213/53 , C07D213/55 , C07D213/64 , C07D213/89 , C07D215/12 , C07D239/26 , C07D241/12 , C07D401/10 , C07D413/10 , C07D417/10
摘要： This invention relates to novel 1-hydroxyimino-3-phenyl-propanes of the formula wherein R1 to R10 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新颖的1-肟基-3-苯基 - 丙烷，其中R 1至R 10如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

66. 发明申请

US20120232051A1 3-AMINO-PYRIDINES AS GPBAR1 AGONISTS 有权
标题翻译： 3-AMINO-PYRIDINES作为GPBAR1 AGONISTS
公开(公告)号：US20120232051A1
公开(公告)日：2012-09-13
申请号：US13406572
申请日：2012-02-28
申请人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
IPC分类号： C07D213/72 , C07D401/04 , A61K31/496 , A61P3/10 , A61K31/444 , C07D413/12 , A61K31/5377 , A61K31/4427 , A61K31/4418 , A61K31/501
CPC分类号： C07D213/75 , C07D213/81 , C07D213/82 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D491/107
摘要： This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新的3-氨基吡啶类，其中B1，B2和R1至R6如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

67. 发明申请

US20120010190A1 1-HYDROXYIMINO-3-PHENYL-PROPANES 有权
标题翻译： 1-羟基亚氨基-3-苯基丙酸酯
公开(公告)号：US20120010190A1
公开(公告)日：2012-01-12
申请号：US13180574
申请日：2011-07-12
申请人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
IPC分类号： A61K31/4409 , C07D401/10 , A61K31/506 , C07D413/10 , A61P3/10 , A61K31/4427 , C07D417/10 , A61P3/00 , A61P29/00 , C07D213/53 , A61K31/5377
CPC分类号： C07C251/48 , C07C2601/02 , C07C2601/14 , C07D213/53 , C07D213/55 , C07D213/64 , C07D213/89 , C07D215/12 , C07D239/26 , C07D241/12 , C07D401/10 , C07D413/10 , C07D417/10
摘要： This invention relates to novel 1-hydroxyimino-3-phenyl-propanes of the formula wherein R1 to R10 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新颖的1-肟基-3-苯基 - 丙烷，其中R 1至R 10如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

68. 发明授权

US07816540B2 Carboxyl- or hydroxyl-substituted benzimidazole derivatives 有权
标题翻译：羧基或羟基取代的苯并咪唑衍生物
公开(公告)号：US07816540B2
公开(公告)日：2010-10-19
申请号：US12331461
申请日：2008-12-10
申请人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
发明人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
IPC分类号： A61K31/4184 , C07D235/18
CPC分类号： C07D401/04 , C07D235/12 , C07D401/12 , C07D401/14
摘要： This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.
摘要翻译：本发明涉及式（I）的新型羧基或羟基取代的苯并咪唑衍生物，其中R 1至R 6如说明书和权利要求书中所定义，以及其生理上可接受的盐和酯。这些化合物与FXR结合，可用作药物。

69. 发明授权

US07790904B2 Substituted benzimidazole derivatives 有权
标题翻译：取代的苯并咪唑衍生物
公开(公告)号：US07790904B2
公开(公告)日：2010-09-07
申请号：US12196355
申请日：2008-08-22
申请人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
发明人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
IPC分类号： A61K31/4184 , C07D235/06
CPC分类号： C07D235/12 , C07D401/12 , C07D405/12
摘要： The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.
摘要翻译：本发明涉及式（I）的新型取代的苯并咪唑衍生物，其中R 1至R 10和X如说明书和权利要求书中所定义，以及其生理学上可接受的盐和酯。这些化合物与FXR结合，可用作药物。

70. 发明授权

US07786109B2 Tricyclic amide derivatives as modulators of H3 receptors 失效
标题翻译：三环酰胺衍生物作为H3受体的调节剂
公开(公告)号：US07786109B2
公开(公告)日：2010-08-31
申请号：US12389619
申请日：2009-02-20
申请人： Matthias Nettekoven , Jean-Marc Plancher , Hans Richter , Olivier Roche , Sven Taylor
发明人： Matthias Nettekoven , Jean-Marc Plancher , Hans Richter , Olivier Roche , Sven Taylor
IPC分类号： C07D487/14
CPC分类号： C07D487/04 , C07D471/14
摘要： The present invention relates to compounds of formula I wherein A, G, r and R1 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors such as, for example, diabetes mellitus.
摘要翻译：本发明涉及式I化合物，其中A，G，r和R 1至R 5如说明书和权利要求书中所定义，及其药学上可接受的盐。该化合物可用于治疗和/或预防与H3受体（例如糖尿病）的调节相关的疾病。

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