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61. 发明申请

WO2008124533A1 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008124533A1
公开(公告)日：2008-10-16
申请号：PCT/US2008/059305
申请日：2008-04-03
申请人： DFINE, INC. , TRUCKAI, Csaba , LUZZI, Robert , SHADDUCK, John, H.
发明人： TRUCKAI, Csaba , LUZZI, Robert , SHADDUCK, John, H.
IPC分类号： A61B17/58 , A61B18/04
CPC分类号： A61B17/8836 , A61B17/8822 , A61B2017/00022
摘要： Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.
摘要翻译：用于将骨水泥输送到骨中的系统和方法可以包括限定流路的手柄主体，手柄主体中的热发射器，以将能量施加到通过流路的骨水泥，骨水泥源和注射套管。套管可以与流动路径连通，使得将套管插入骨头可以允许骨水泥通过其穿过套管远端的开口。用于将骨水泥输送到骨头中的其它系统和方法可以包括具有手柄部分的注射器主体和套管，骨水泥容器，低压驱动机构，其被配置为实现骨粘固剂从所述容器流到喷射器主体以及高压驱动机构，其构造成使得骨水泥通过所述注射器主体流入所述骨中。

62. 发明申请

WO2007028120A3 SYSTEMS AND METHODS FOR SENSING RETROGRADE FLOWS OF BONE FILL MATERIAL 审中-公开
标题翻译：用于感测骨填充材料的逆向流动的系统和方法
公开(公告)号：WO2007028120A3
公开(公告)日：2007-05-31
申请号：PCT/US2006034409
申请日：2006-09-01
申请人： DFINE INC , TRUCKAI CSABA , SHADDUCK JOHN
发明人： TRUCKAI CSABA , SHADDUCK JOHN
IPC分类号： A61F2/46 , A61B17/88
CPC分类号： A61B17/8836 , A61B17/8811 , A61B17/8822 , A61B2017/00022 , A61B2017/00084 , A61B2090/064 , A61F2/44 , A61F2/4601
摘要： The present invention relates in certain embodiments to medical devices, systems and methods for use in osteoplasty procedures, such as vertebral compression fractures. One device includes an elongated sleeve configured for introduction into a bone and delivery of bone fill material therethrough into the bone. A sensor is disposed on the sleeve and can sense a retrograde flow of bone fill material proximate the sensor. One system includes such a device and a controller configured to receive signals from the sensor and to control at least one parameter of bone fill material flow into the bone based in part on said signals. One method includes flowing a bone fill material through an introducer into a vertebral body along a first direction and sensing a flow of said bone fill material about an outer surface of the introducer in a second direction different from said first direction.
摘要翻译：本发明在某些实施例中涉及用于诸如椎骨压缩性骨折之类的骨整形手术中的医疗装置，系统和方法。一种装置包括细长的套筒，该细长的套筒被构造用于引入到骨中并且将骨填充材料通过其传送到骨中。传感器设置在套管上并且可以感测接近传感器的骨填充材料的逆行流动。一个系统包括这样的装置和控制器，该控制器被配置为从传感器接收信号并且部分地基于所述信号控制骨填充材料流入骨中的至少一个参数。一种方法包括使骨填充材料沿着第一方向流过导引器进入椎体，并且感测所述骨填充材料在不同于所述第一方向的第二方向上围绕导引器的外表面的流动。

63. 发明申请

WO2006062939A3 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2006062939A3
公开(公告)日：2006-08-03
申请号：PCT/US2005044055
申请日：2005-12-06
申请人： DFINE INC , TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
发明人： TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
IPC分类号： A61F2/28 , A61B18/00 , A61L24/02
CPC分类号： A61B18/14 , A61B17/7095 , A61B17/7098 , A61B17/8811 , A61B17/8822 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2018/00565 , A61F2/44 , A61L27/50 , A61L2430/38
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A system 100 utilizes Rf energy in combination a conductive bone fill material 120 for polymerizing the surface of the inflow plume 165 to control the geometry of the fill material 120 and the application of force caused by inflows of fill material 120. In another embodiment, the method of treating bone includes injecting a volume of fill material 120 into a bone and selectively modifying a viscosity of a selected portion of the bone fill material 120 to control the direction of flow of the fill material 120 within the bone 90. The method can also include controlling at least one flow parameter of the flow of bone fill material 120. A system 100 for treating bone using this method includes an introducer 110A, 110B for delivering fill material 120 into the bone 90 and an energy source 125A selectively coupleable to the fill material 120 to alter the viscosity of the fill material 120 as it flows out of the introducer 110A, 110B.
摘要翻译：本发明在某些实施方案中涉及用于治疗诸如椎骨压缩性骨折之类的骨整形手术的医疗装置。更具体地说，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的器械和方法。系统100利用Rf能量结合导电骨填充材料120来聚合流入羽流165的表面以控制填充材料120的几何形状和由填充材料120的流入引起的力的施加。在另一个实施例中，治疗骨的方法包括将一定体积的填充材料120注入到骨中并选择性地改变骨填充材料120的选定部分的粘度以控制填充材料120在骨90内的流动方向。该方法还可以包括控制骨填充材料120的流动的至少一个流动参数。用于使用该方法治疗骨骼的系统100包括用于将填充材料120输送到骨骼90中的导入器110A，110B以及可选择地与填充物耦合的能量源125A 材料120以在填充材料120流出导引器110A，110B时改变填充材料120的粘度。

64. 发明授权

US11344350B2 Articulating osteotome with cement delivery channel and method of use 有权
公开(公告)号：US11344350B2
公开(公告)日：2022-05-31
申请号：US16680056
申请日：2019-11-11
申请人： DFine, Inc.
发明人： Craig Purdy , Dan Balbierz
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00 , A61B17/88 , A61B17/16 , A61B17/34 , A61B17/00 , A61B18/00
摘要： The present disclosure illustrates an osteotome for treating hard tissue and methods of use. The osteotome embodiments described herein include a shaft with a working end configured to displace hard tissue and a lumen to deliver material through the shaft. The working end may create pathways by selectively transitioning from a linear to a non-linear configuration. The lumen may deliver material through the shaft while the working end is in a linear or a non-linear configuration allowing precise filling of the pathways.

65. 发明授权

US11172970B2 High-pressure syringe with pressure reduction 有权
公开(公告)号：US11172970B2
公开(公告)日：2021-11-16
申请号：US16745172
申请日：2020-01-16
申请人： DFine, Inc.
发明人： Craig Purdy , Eron Flory , David J. Johnson , Nate Shirley
IPC分类号： A61B17/88 , A61B17/56
摘要： Devices used to pressurize, depressurize, or otherwise displace fluid are disclosed. The devices may be configured as a syringe. The syringe may be configured to generate high-pressure within the syringe to inflate or deflate a medical device, such as a balloon, or to inject a substance, such as bone cement, into a bone, such as a vertebra. The syringe may include a pressure reduction mechanism used to depressurize the syringe.

66. 发明授权

US11116570B2 Tumor ablation devices and related methods 有权
公开(公告)号：US11116570B2
公开(公告)日：2021-09-14
申请号：US15822944
申请日：2017-11-27
申请人： DFine, Inc.
发明人： Craig Purdy , Dan Balbierz
IPC分类号： A61B18/00 , A61B18/14 , A61B18/08 , A61B18/10 , A61B18/28
摘要： Spinal tumor ablation devices and related systems and methods are disclosed. Some spinal tumor ablation devices include electrodes that are fixedly offset from one another. Some spinal tumor ablation devices include a thermal energy delivery probe that has at least one temperature sensor coupled thereto. The position of the at least one temperature sensor relative to other components of the spinal tumor ablation device may be controlled by adjusting the position of the thermal energy delivery probe in some spinal tumor ablation devices. Some spinal tumor ablation devices are configured to facilitate the delivery of a cement through a utility channel of the device.

67. 发明授权

US10172659B2 Bone treatment systems and methods 有权
公开(公告)号：US10172659B2
公开(公告)日：2019-01-08
申请号：US15477678
申请日：2017-04-03
申请人： DFINE, Inc.
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/88 , A61B17/00 , A61F2/44 , A61B17/70 , A61B17/56
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.

68. 发明授权

US10136934B2 Bone treatment systems and methods 有权
公开(公告)号：US10136934B2
公开(公告)日：2018-11-27
申请号：US14741864
申请日：2015-06-17
申请人： DFINE, INC.
发明人： Csaba Truckai , Robert Luzzi , Andrew Kohm , John H. Shadduck
IPC分类号： A61B17/88 , A61B17/00 , A61B90/00
摘要： Systems and methods for treating vertebral compression fractures are discussed. In an embodiment, a method includes mixing bone cement precursors thereby causing a first chemical curing reaction characterized by a first time-viscosity profile, controllably applying energy to the bone cement from an external source to modify the first time-viscosity profile to a second time-viscosity profile, and injecting the cement into bone at a substantially constant viscosity greater than about 1000 Pa·s to greater than about 5000 Pa·s over an extended working time. In another embodiment, a bone cement injector system is provided that includes a first handle component that is detachably coupled to a second sleeve component having a distal end for positioning in bone and a flow channel extending through the first and second components. The system includes first and second thermal energy emitters for delivering energy to bone cement flows in a flow channel portion in the first and second components, respectively.

69. 发明申请

US20180193036A1 OSTEOTOME WITH A DISTAL PORTION FOR SIMULTANEOUS ADVANCEMENT AND ARTICULATION 审中-公开
公开(公告)号：US20180193036A1
公开(公告)日：2018-07-12
申请号：US15862441
申请日：2018-01-04
申请人： DFine, Inc.
发明人： Craig Purdy , Dan Balbierz
IPC分类号： A61B17/16
摘要： Medical devices for creating or expanding a cavity within bone of a patient are disclosed. In some circumstances, a medical device, such as an osteotome is designed to facilitate simultaneous advancement and articulation of a distal portion of the osteotome. Simultaneous advancement and articulation of the distal portion may reduce one or more forces on the distal portion of the osteotome relative to other methods in which advancement and articulation are separated in time, thereby decreasing the risk of breakage or other damage to the osteotome.

70. 发明申请

US20180161047A1 MEDICAL DEVICES FOR TREATING HARD TISSUES AND RELATED METHODS 审中-公开
公开(公告)号：US20180161047A1
公开(公告)日：2018-06-14
申请号：US15836241
申请日：2017-12-08
申请人： DFine, Inc.
发明人： Craig Purdy , Dan Balbierz , Nate Shirley , Jose Galdos
IPC分类号： A61B17/16 , A61B17/34
摘要： Medical devices such as osteotomes are provided. The medical device may include inner and outer members that form a working end portion. Distal end portions of the inner and outer members can cooperate to allow deflection of the working end portion. Medical devices including indicators are also provided. The indicator may communicate a direction of deflection of the working end portion to a practitioner. Additionally, medical devices including torque release mechanisms are provided. The torque release mechanism may uncouple a first portion of the medical device from a second portion of the medical device when an amount of torque applied to the medical device exceeds a predetermined value. The torque release mechanism may limit damage to components of the medical device during use of the medical device.

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