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61. 发明公开

EP3068870A1 A SYSTEM AND METHOD FOR PROCESSING OF BIOLOGICAL TISSUE SAMPLES 有权
标题翻译：系统VERFAHREN ZUR VERARBEITUNG生物学家GEWEBEPROBEN
公开(公告)号：EP3068870A1
公开(公告)日：2016-09-21
申请号：EP14809124.2
申请日：2014-11-12
申请人： Stempeutics Research Private Limited
发明人： MURALI, Cherat , ALOK, Damle , SWATHI, Sundar Raj , ANISH SEN, Majumdar , ABHIJEET, Deshmukh , BYALAPPA, MANJUNATH, Sathya Kumar , PRAJOD THIRUVAMPATTIL, Lohidhakshan
IPC分类号： C12N5/071 , C12M1/00 , C12M1/34 , C12M1/33
摘要： The present disclosure provides an automated system for processing of tissue. The system comprises a plurality of containers for storing at least one of tissue samples, buffer solutions, enzymes and other reagents, tissue processing container for processing of the tissue, and a robotic assembly coupled to the tissue processing container. The robotic assembly is configured to: carry the tissue processing container towards each of the plurality of containers, and align an inlet port of the tissue processing container with an outlet port of each of the plurality of containers for collecting the liquids, and moves the tissue processing container in multiple-planes to perform at least one of the washing processes, digestion process, phase separation process and combination thereof. The system also comprises of a control unit interfaced with the robotic assembly for controlling operations of the robotic assembly while processing the tissue.
摘要翻译：本公开提供了一种用于处理组织的自动化系统。该系统包括多个用于储存组织样本，缓冲溶液，酶和其它试剂中的至少一种的容器，用于处理组织的组织处理容器以及耦合到组织处理容器的机器人组件。所述机器人组件被配置为：朝向所述多个容器中的每一个携带所述纸张处理容器，并且将所述纸巾处理容器的入口与所述多个容器中的每一个的出口端口对准以收集液体，并移动所述组织处理容器在多平面中进行洗涤过程，消化过程，相分离处理及其组合中的至少一个。该系统还包括与机器人组件接口的控制单元，用于在处理组织的同时控制机器人组件的操作。

63. 发明公开

EP2999787A1 COVALENTLY CLOSED NON-CODING IMMUNOMODULATORY DNA CONSTRUCT 有权
标题翻译：共价闭合编码NOT-免疫调节DNA构建体
公开(公告)号：EP2999787A1
公开(公告)日：2016-03-30
申请号：EP15706416.3
申请日：2015-02-18
申请人： Mologen AG
发明人： KLEUSS, Christiane , KAPP, Kerstin , WITTIG, Burghardt , SCHROFF, Matthias
IPC分类号： C12N15/113
CPC分类号： C12N15/117 , A61K39/39 , A61K48/00 , A61K2039/55561 , C12N2310/17 , C12N2310/532 , C12N2320/31
摘要： The present invention relates to a covalently closed DNA construct, a pharmaceutical composition and a vaccine and their use for the modulation of the immune system. It provides a DNA construct for immunomodulation comprising a specific DNA sequence.

64. 发明公开

EP2998246A1 DEVICE FOR TRANSPORTATION, SEPARATION AND ORIENTATION OF CUVETTES 审中-公开
标题翻译： VORRICHTUNGFÜR运输，TRENNUNG UND AUSRICHTUNG VONKÜVETTEN
公开(公告)号：EP2998246A1
公开(公告)日：2016-03-23
申请号：EP15180969.6
申请日：2015-08-13
申请人： Stratec Biomedical AG
发明人： Sachs, Alexander
IPC分类号： B65G33/04
CPC分类号： B65G33/04 , B65G47/1471 , B65G47/24 , G01N35/04 , G01N2035/0406 , G01N2035/0487
摘要： The invention relates to a device, a system and a method for transportation, separation and orientation in a head up position of cuvettes. The invention also relates to using the device or the system for transportation, separation and orientation in head up position of the cuvettes. The device comprises a pipe, a rotating auger, a motor, a guiding plate and a slide rail. The system further comprises at least one cuvette.
摘要翻译：本发明涉及一种用于在比色杯的头部位置中运输，分离和取向的装置，系统和方法。本发明还涉及使用该装置或系统在比色杯的抬头位置中的运输，分离和取向。该装置包括管，旋转螺旋钻，马达，引导板和滑轨。该系统还包括至少一个比色皿。

65. 发明公开

EP2994479A1 MODIFIED EXPRESSION OF PROLYL-4-HYDROXYLASE IN PHYSCOITRELLA PATENS 有权转让
标题翻译：脯氨酰4-羟化酶PHYSCOITRELLA藓的改良表达
公开(公告)号：EP2994479A1
公开(公告)日：2016-03-16
申请号：EP14720988.6
申请日：2014-05-05
申请人： Baden-Württemberg Stiftung gGmbH
发明人： RESKI, Ralf , PARSONS, Juliana , ALTMANN, Friedrich , GRAF, Manuela , DECKER, Eva , STADLMANN, Johannes
IPC分类号： C07K14/415 , C12N15/82 , C12N9/06
CPC分类号： C12N15/8242 , A61K38/00 , C07K14/415 , C07K14/505 , C12N9/0012 , C12N9/0071 , C12N15/8218 , C12N15/8257 , C12Y114/11002
摘要： The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.

66. 发明公开

EP2791254A2 FUNCTIONALISED SILICON NANOPARTICLES 有权转让
标题翻译：功能化的硅纳米颗粒
公开(公告)号：EP2791254A2
公开(公告)日：2014-10-22
申请号：EP12799206.3
申请日：2012-12-12
申请人： Westfälische Wilhelms-Universität Münster , Helmholtz-Zentrum Dresden - Rossendorf e.V. , De Cola, Luisa , Stephan, Holger , Bergmann, Ralf , Ruffani, Alexander
发明人： DE COLA, Luisa , STEPHAN, Holger , BERGMANN, Ralf , RUFFANI, Alexander
IPC分类号： C09C1/28 , A61K9/20 , C01B33/02
CPC分类号： A61K9/5123 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/65 , A61K33/24 , A61K47/54 , A61K47/6923 , A61K49/0093 , A61K51/1244 , B82Y30/00 , C01B33/02 , C01B33/027 , C01P2002/82 , C01P2002/84 , C01P2004/04 , C01P2004/64 , C01P2004/84 , C01P2006/42 , C07F7/0827 , C09C1/28 , C09C1/3063 , Y10T428/2982
摘要： The present invention is related to silicon nanoparticles, a pharmaceutical composition comprising silicon nanoparticles, a method for synthesis of the silicon nanoparticles and their use for in vivo diagnostics, visualization of drug delivery or staining of cells, biological processes or pathways. The silicon nanoparticles are characterised that they comprise a silicon core of a size of 1 to 10 nm and are terminated with allylamine or poly(allylamine) comprising up to 10 allylamine groups.

67. 发明公开

EP2681228A1 PLATINUM COMPLEXES AND THEIR USE 有权
标题翻译：铂配合使用
公开(公告)号：EP2681228A1
公开(公告)日：2014-01-08
申请号：EP12707291.6
申请日：2012-03-01
申请人： Westfälische Wilhelms-Universität Münster
发明人： DE COLA, Luisa , MAURO, Matteo , SEDA KEHR, Nermin , STRASSERT, Cristian Alejandro
IPC分类号： C07F15/00
CPC分类号： C07F15/0093 , C07D401/04 , C07D401/14 , C09K11/06 , C09K2211/1029 , C09K2211/1044 , C09K2211/1059 , C09K2211/185 , H01L51/0087 , H01L51/5016 , H05B33/14
摘要： The invention relates to platinum complexes and their use in biomedical applications, like in vitro and in vivo imaging and cell staining. The present invention provides new materials and their use as imaging agent. The formation of luminescent aggregates can allow a switch of the emission leading to a dynamic label and on the formation of soft assemblies, which, in some cases, are even more emissive than the isolated corresponding species.

68. 发明授权

EP1951870B1 DNA-KONSTRUKTE ZUR SPEZIFISCHEN HEMMUNG DER GENEXPRESSION DURCH RNA-INTERFERENZ 有权
标题翻译： DNA构建体用于通过RNA干扰基因表达的特异性抑制
公开(公告)号：EP1951870B1
公开(公告)日：2013-04-24
申请号：EP06805529.2
申请日：2006-11-22
申请人： Mologen AG
发明人： SCHROFF, Matthias , OSWLAD, Detlef
IPC分类号： C12N15/113 , C12N15/10
CPC分类号： C12N15/111 , C12N15/113 , C12N2310/111 , C12N2310/14 , C12N2310/52 , C12N2310/53 , C12N2330/30

69. 发明公开

EP2424988A1 CONCATAMERS FOR IMMUNEMODULATION 审中-公开
标题翻译：联体可用于免疫调节
公开(公告)号：EP2424988A1
公开(公告)日：2012-03-07
申请号：EP10715870.1
申请日：2010-04-30
申请人： Mologen AG
发明人： SCHROFF, Matthias , WITTIG, Burghardt , SCHMIDT, Manuel , KLEUSS, Christiane
IPC分类号： C12N15/117 , A61K31/713
CPC分类号： C12N15/117 , C12N2310/17 , C12N2310/51 , C12N2310/53 , C12N2320/31
摘要： The invention relates to a polymeric, non-coding nucleic acid molecule for modulation of the activity of the human and animal immune system as well as a method for the manufacture thereof and a vaccine, comprising the polymeric, non-coding nucleic acid molecule, wherein polymeric, non-coding nucleic acid molecules may be understood as non-coding nucleic acid molecules, comprising at least four covalently bound molecules (tetramer) or are assemblies of more non-coding nucleic acid molecules (high molecular polymers) which are covalently bound to each other.

70. 发明公开

EP4416697A1 VERFAHREN UND EINE VORRICHTUNG ZUR OPTISCHEN ERKENNUNG UND ANALYSE IN EINER BEWEGUNGSUMGEBUNG 审中-公开
公开(公告)号：EP4416697A1
公开(公告)日：2024-08-21
申请号：EP22838797.3
申请日：2022-12-16
申请人： Heero Sports GmbH
发明人： SIEKMANN, Pascal , DICK, Gerhard
IPC分类号： G06V10/147 , G06T7/50 , G06V10/82 , G06V40/20
CPC分类号： G06V40/23 , G06V10/82 , G06V10/147

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