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    • 63. 发明公开
    • N-아세틸글루코사민 유도체 및 그의 용도
    • N-乙酰胆碱胺衍生物及其用途
    • KR1020050071557A
    • 2005-07-07
    • KR1020057006063
    • 2003-07-25
    • 가오 가부시키가이샤
    • 미우라,교꼬사요,데쯔야사까이,신고이노우에,신따로
    • C07H5/06C07H5/04A61K31/7008A61K8/60
    • C07H13/06A61K8/60A61Q17/04A61Q19/00A61Q19/08A61Q19/10C07H15/04
    • An acetylated N-acetylglucosamine derivative represented by the following general formula (1) and a hyaluronic acid production promoter containing the same and a skin preparation for external use containing the same. General formula (1): wherein R1 represents hydrogen or C2-18 alkyl; R 2, R3 and R4 may be either the same or different and each represents hydrogen or C2-18 acyl; and the stereostructure at the 1- position may be either alpha- or beta-structure, provided that R 1, R2, R3 and R4 do not represent hydrogen at the same time. It is intended to provide an easily available hyaluronic acid production promoter and a skin preparation for external use by which the production of hyaluronic acid can be promoted in the skin and thus the skin can be maintained in a firm and moisten state so that it is expected that the human skin can be prevented from aging.
    • 由以下通式(1)表示的乙酰化N-乙酰葡糖胺衍生物和含有该乙酰化N-乙酰氨基葡糖衍生物的含有该乙酰化N-乙酰葡糖胺衍生物的含有该乙酰化N- 通式(1):其中R1表示氢或C2-18烷基; R 2,R 3和R 4可以相同或不同,各自表示氢或C 2-3-18酰基; 并且1-位置的立体结构可以是α-或β-结构,条件是R 1,R 2,R 3和R 4不同时代表氢。 旨在提供容易获得的透明质酸生产促进剂和外用皮肤制剂,通过其可以在皮肤中促进透明质酸的产生,因此皮肤可以保持在稳定和润湿状态,从而预期 可以防止人体皮肤老化。
    • 70. 发明公开
    • 산성 수중유형 유화 조성물
    • 酸性油包水型乳化组合物
    • KR1020040004116A
    • 2004-01-13
    • KR1020030044242
    • 2003-07-01
    • 가오 가부시키가이샤
    • 구도우나오토나카지마요시노부사토우마코토스기우라마사카츠야마구치히로아키미야타니츠카사
    • A23L1/24
    • A23D7/011A23D7/0053A23L27/60
    • PURPOSE: Provided is an acidic oil-in-water type emulsified composition, which composition is excellent in taste and appearance stability, has resistance against pressure-induced shear stress which occurs upon preparation or use, shows less changes in physical properties, for example, viscosity reduction can be suppressed, and is free from appearance change such as oil/water separation. CONSTITUTION: The acidic oil-in-water type emulsified composition comprises the following components of: (A) an oil or fat having a diglyceride content of 30 wt. % or greater, (B) an egg yolk, the egg yolk containing a lysophospholipid and a phospholipid, and (C) a water soluble soybean polysaccharide, wherein the lysophospholipid is partially or entirely derived from the egg yolk; the lysophospholipid is partially or entirely derived from an enzyme treated egg yolk; the weight percentage of the lysophospholipid to the total phospholipid is 15% or greater in terms of a phosphorous amount; the enzyme is selected from the group consisting of esterases, lipases, phospholipases, and mixtures thereof; the composition further comprises a phytosterol, phytosterol esters, and mixtures thereof; and the composition is obtained by subjecting an aqueous phase containing the egg yolk to mechanical treatment to heighten the viscosity by at least 50% or reducing the solubility of the egg yolk protein by 5 to 60%, each compared with that before the treatment, and then adding an oil phase containing the component (A).
    • 目的:提供一种酸性水包油型乳化组合物,该组合物的味道和外观稳定性优异,在制备或使用时发生压力诱导剪切应力的抗性,物理性能的变化较小, 可以抑制粘度降低,并且没有油/水分离等外观变化。 构成:酸性水包油型乳化组合物包含以下成分:(A)甘油二酯含量为30重量%的油或脂肪。 %以上,(B)蛋黄,含有溶血磷脂和磷脂的蛋黄,(C)水溶性大豆多糖,其中溶血磷脂部分或全部来自蛋黄; 溶血磷脂部分或完全衍生自经酶处理的蛋黄; 溶血磷脂与总磷脂的重量百分数相对于磷量为15%以上; 该酶选自酯酶,脂肪酶,磷脂酶及其混合物; 所述组合物还包含植物甾醇,植物甾醇酯及其混合物; 并且通过对含有蛋黄的水相进行机械处理,将粘度提高至少50%,或者将蛋黄的溶解度降低5〜60%,与处理前相比,可以获得组成,以及 然后加入含有组分(A)的油相。