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51. 发明授权

US10476517B2 Modulator for a digital amplifier 有权
公开(公告)号：US10476517B2
公开(公告)日：2019-11-12
申请号：US16092883
申请日：2017-04-12
申请人： Forschungsverbund Berlin e.V.
发明人： Florian Hühn
IPC分类号： H03M3/00 , H03F3/189 , H03F3/217 , H03F3/38 , H03F3/387 , H04L27/20
摘要： The present disclosure relates to a modulator for a digital amplifier and a device comprising such a modulator and a digital amplifier.The modulator includes a pulse shaper and a control unit for controlling the pulse shaper to convert an input signal into a bit stream configured for a digital amplifier which encodes an amplitude value per clock of a carrier signal. The pulse shaper can represent a respective amplitude value of the input signal with different bit patterns. The control unit includes an assignment of the control commands to associated amplitude values resulting from amplification of the associated bit patterns with the digital amplifier is stored or at least is provided in that the control unit selects a control command per clock by means of the assignment and the amplitude value of the input signal and drives the pulse shaper accordingly.

52. 发明授权

US10416081B2 Optical system and method for spectroscopy 有权
公开(公告)号：US10416081B2
公开(公告)日：2019-09-17
申请号：US15725448
申请日：2017-10-05
申请人： Forschungsverbund Berlin e.V.
发明人： Bernd Sumpf , Martin Maiwald
IPC分类号： G01N21/65 , G01N21/53 , G01N15/14 , G01N15/10
摘要： Optical systems and methods for spectroscopy are described. The optical system may be particularly suitable for Raman spectroscopy and includes a multispectral excitation source, designed to emit monochromatic excitation radiation successively at at least two different excitation wavelengths along a common beam axis; an elongated flow volume with a longitudinal axis, designed to direct a particle flow along the longitudinal axis; an excitation beam path, designed to irradiate the monochromatic excitation radiation into the flow volume at a first position and the second position that are located in the flow volume and the first position is spaced apart from the second position; and a detection device, designed to wavelength-selectively filter and detect a portion of a radiation scattered from the first position at a first filter wavelength and to wavelength-selectively filter and detect a portion of a radiation scattered from the second position at a second filter wavelength.

53. 发明申请

US20190134024A1 ANTAGONISTS OF THE THYROID-STIMULATING HORMONE RECEPTOR (TSHR) 审中-公开
公开(公告)号：US20190134024A1
公开(公告)日：2019-05-09
申请号：US16096868
申请日：2017-04-26
申请人： Forschungsverbund Berlin e.V.
发明人： Gerd KRAUSE , Inna HOYER , Edgar SPECKER , Jens FURKERT , Patrick MARCINKOWSKI , Jens-Peter VON KRIES , Martin NEUENSCHWANDER , Marc NAZARE
IPC分类号： A61K31/495 , A61K31/429 , A61P35/00 , A61P5/14
CPC分类号： A61K31/495 , A61K31/429 , A61P5/14 , A61P35/00
摘要： Chemical compounds are useful in the treatment of a subject afflicted by a thyroid disease. The compounds exhibit activity as thyroid-stimulating hormone receptor (TSHR) antagonists and can be used in the treatment of hyperthyroidism, Graves' disease, Graves' Ophthalmopathy and thyroid cancer.

54. 发明申请

US20180051025A1 XANTHINE DERIVATIVES, THEIR USE AS A MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE SAME 审中-公开
公开(公告)号：US20180051025A1
公开(公告)日：2018-02-22
申请号：US15552556
申请日：2016-02-24
申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN , FORSCHUNGSVERBUND BERLIN E.V.
发明人： Michael BADER , Edgar SPECKER , Susann MATTHES , Anja SCHÜTZ , Keven MALLOW , Maik GROHMANN , Marc NAZARÉ
IPC分类号： C07D473/06 , C07D519/00
CPC分类号： C07D473/06 , C07D487/04 , C07D519/00
摘要： The invention relates to a xanthine derivative defined by chemical formula I or a salt thereof, its use as a medicament, especially for use in the treatment of serotonin-related diseases or disorders, and a pharmaceutical preparation comprising the xanthine derivative. The novel xanthine compounds are capable of inhibiting tryptophan hydroxylases (TPH) involved in the biosynthesis of serotonin and are effective in influencing the serotonin level in the body.

55. 发明授权

US09563061B2 Device having an arrangement of optical elements 有权
标题翻译：具有光学元件布置的装置
公开(公告)号：US09563061B2
公开(公告)日：2017-02-07
申请号：US14427437
申请日：2013-09-12
申请人： FORSCHUNGSVERBUND BERLIN E.V.
发明人： Martin Maiwald , Bernd Sumpf
IPC分类号： G02B5/18 , G02B27/10 , G01J3/44 , G01N21/65 , G02B27/14 , G01J3/427 , G02B27/09 , G01N21/39
CPC分类号： G02B27/1006 , G01J3/427 , G01J3/44 , G01J2003/4424 , G01N21/65 , G01N2021/399 , G01N2201/0221 , G01N2201/024 , G02B27/09 , G02B27/1086 , G02B27/141
摘要： A device (122) is described having an arrangement of optical elements comprising excitation light sources (101, 115) for generating individual light beams (102, 116) having different wavelengths for exciting a sample in such a way that light scattered back from the sample as a result of the excitation is made available to a Raman spectroscopic analysis. The device (122) has deflection devices (103, 117) associated with the individual light beams (102, 116) for deflecting the individual light beams (102, 116) onto a common light path, wherein the common light path has a same optical system (109) for focusing the light beams (102, 116).
摘要翻译：描述了一种装置（122），其具有包括激发光源（101,115）的光学元件的布置，用于产生具有不同波长的单个光束（102,116），以使样品激发，使得从样品散射回来的光作为激发的结果可用于拉曼光谱分析。所述装置（122）具有与各个光束（102,116）相关联的偏转装置（103,117），用于将各个光束（102,116）偏转到公共光路上，其中公共光路具有相同的光系统（109），用于聚焦光束（102,116）。

56. 发明授权

US09343873B2 Laser diode with high efficiency 有权
标题翻译：激光二极管效率高
公开(公告)号：US09343873B2
公开(公告)日：2016-05-17
申请号：US13823277
申请日：2011-09-12
申请人： Paul Crump , Goetz Erbert , Hans Wenzel
发明人： Paul Crump , Goetz Erbert , Hans Wenzel
IPC分类号： H01S5/00 , H01S5/20 , H01S5/22 , A61B18/20 , A61B18/00 , A61B19/00 , H01S5/32
CPC分类号： H01S5/20 , A61B18/203 , A61B2018/00476 , A61B2090/049 , H01S5/2031 , H01S5/22 , H01S5/3213 , H01S2301/185
摘要： It is the object of the present invention to specify a light source with high efficiency and high eye safety at the same time.For this purpose, the active layer (10), the first cladding layer (14), the first waveguide layer (12), the second waveguide layer (16), and the second cladding layer (18) should be designed such that 0.01 μm≦dwL≦1.0 μm and Δn≧0.04, where dwL is the sum total of the layer thickness of the first waveguide layer (12), the layer thickness of the active layer (10), and the layer thickness of the second waveguide layer (16) and Δn is a maximum of the refractive index difference between the first cladding layer (14) and the first waveguide layer (12) and the refractive index difference between the second waveguide layer (16) and the second cladding layer (18).
摘要翻译：本发明的目的是同时具有高效率和高眼睛安全性的光源。为此，应设计有源层（10），第一覆层（14），第一波导层（12），第二波导层（16）和第二覆层（18），使得0.01μm＆ ; dwL＆nlE;1.0μm和＆Dgr;n≥0.04，其中dwL是第一波导层（12）的层厚度的总和，有源层（10）的层厚度和第二波导的层厚度层（16）和＆Dgr; n是第一包层（14）和第一波导层（12）之间的折射率差的最大值和第二波导层（16）与第二包层之间的折射率差（18）。

57. 发明授权

US09210789B2 Device and method for generating a plasma by means of a traveling wave resonator 有权
标题翻译：用于通过行波谐振器产生等离子体的装置和方法
公开(公告)号：US09210789B2
公开(公告)日：2015-12-08
申请号：US13508607
申请日：2010-11-19
申请人： Horia-Eugen Porteanu , Roland Gesche , Silvio Kuehn
发明人： Horia-Eugen Porteanu , Roland Gesche , Silvio Kuehn
IPC分类号： B23K9/00 , B23K9/02 , H05H1/46 , H05H1/24
CPC分类号： H05H1/46 , H05H1/24 , H05H2001/466
摘要： A device for generating a plasma, comprises an alternating voltage source, a travelling wave resonator and coupling means that are designed to couple the alternating voltage generated by the alternating voltage source into the travelling wave resonator in such a manner that travelling electromagnetic waves are produced, wherein the travelling wave resonator is designed to increase the electric field strength of the travelling electromagnetic waves in such a manner that a plasma is ignited in a gas. The invention further relates to a method for generating a plasma, comprising the steps of: generating an alternating voltage; generating travelling electromagnetic waves in a travelling wave resonator by coupling said alternating voltage into the travelling wave resonator; and increasing the electric field strength of the travelling electromagnetic waves in the travelling wave resonator in order to ignite a plasma in a gas.
摘要翻译：一种用于产生等离子体的装置，包括交流电压源，行波谐振器和耦合装置，其被设计成以产生行进电磁波的方式将由交流电压源产生的交流电耦合到行波谐振器中，其特征在于，所述行波谐振器被设计成以等离子体在气体中点燃的方式增加所述行进电磁波的电场强度。本发明还涉及一种用于产生等离子体的方法，包括以下步骤：产生交流电压; 通过将所述交流电压耦合到行波谐振器中，在行波谐振器中产生行波电磁波; 并且增加行波谐振器中的行进电磁波的电场强度，以点燃气体中的等离子体。

58. 发明授权

US09102667B2 N-arylaminomethylene benzothiophenones for treatment of cardiovascular disease 有权
标题翻译：用于治疗心血管疾病的N-芳基氨基亚甲基苯并噻吩酮
公开(公告)号：US09102667B2
公开(公告)日：2015-08-11
申请号：US13980057
申请日：2012-01-18
申请人： Enno Klussmann , Walter Rosenthal , Jelena Milic , Martin W. Bergmann
发明人： Enno Klussmann , Walter Rosenthal , Jelena Milic , Martin W. Bergmann
IPC分类号： C07D417/12 , C07D403/12 , C07D413/12 , A61K31/135 , A61K31/343 , A61K31/381 , A61K31/428 , A61K31/4402 , A61K31/4406 , A61K31/4427 , A61K31/47 , A61K31/4709 , C07D333/64 , C07D409/12
CPC分类号： C07D417/12 , A61K31/135 , A61K31/343 , A61K31/381 , A61K31/428 , A61K31/4402 , A61K31/4406 , A61K31/4427 , A61K31/47 , A61K31/4709 , C07D333/64 , C07D403/12 , C07D409/12 , C07D413/12
摘要： The invention relates to N-arylaminomethylenebenzothiophenones of General Formula (I) for use as a drug for the treatment of cardiovascular diseases: wherein E is S, O, or CH2, D is CH or NH, and Ar is a phenyl or naphtyl moiety substituted by an electron-withdrawing group, an unsubstituted heteroaryl residue, or a heteroaryl residue substituted by alkyl or an electron-withdrawing group.
摘要翻译：本发明涉及用作治疗心血管疾病的药物的通式（I）的N-芳基氨基亚甲基苯并苯乙酮：其中E是S，O或CH 2，D是CH或NH，Ar是取代的苯基或萘基部分通过吸电子基团，未取代的杂芳基残基或被烷基或吸电子基团取代的杂芳基。

59. 发明授权

US08987713B2 Arrangement for generating electromagnetic radiation 有权
标题翻译：用于产生电磁辐射的布置
公开(公告)号：US08987713B2
公开(公告)日：2015-03-24
申请号：US13643767
申请日：2011-04-20
申请人： Fritz Henneberger , Henning Riechert , Norbert Koch
发明人： Fritz Henneberger , Henning Riechert , Norbert Koch
IPC分类号： H01L35/24 , H01L51/50 , B82Y20/00 , H01L51/52 , H01L51/56
CPC分类号： H01L51/5088 , B82Y20/00 , H01L51/52 , H01L51/56
摘要： The invention relates, inter alia, to an arrangement (10) for generating electromagnetic radiation, wherein the arrangement comprises inorganic semiconductor material and organic material (130), characterized by a semiconductor cylinder (30, 40) composed of inorganic semiconductor material and a charge carrier injection zone (50) situated in the semiconductor cylinder, wherein the charge carrier injection zone adjoins the lateral surface (110) of the semiconductor cylinder, the organic material (130) is suitable for emitting electromagnetic radiation in the case of a charge carrier recombination, and the organic material bears indirectly or directly on that section of the lateral surface of the semiconductor cylinder which is adjoined by the charge carrier injection zone and electron-hole pairs from the charge carrier injection zone of the semiconductor cylinder can enter into the organic material, and excite there the emission of electromagnetic radiation by recombination.
摘要翻译：本发明尤其涉及用于产生电磁辐射的装置（10），其中所述装置包括无机半导体材料和有机材料（130），其特征在于由无机半导体材料和电荷组成的半导体圆柱体（30,40）载流子注入区（50），其中所述电荷载体注入区毗邻所述半导体圆柱体的侧表面（110），所述有机材料（130）适用于在电荷载体复合的情况下发射电磁辐射并且有机材料间接地或直接地在与电荷载体注入区相邻的半导体圆柱体的侧表面的该部分上承载，并且来自半导体圆柱体的电荷载体注入区的电子 - 空穴对可以进入有机材料并通过重组激发电磁辐射的发射。

60. 发明授权

US08809968B2 Semiconductor layer structure 有权
标题翻译：半导体层结构
公开(公告)号：US08809968B2
公开(公告)日：2014-08-19
申请号：US13888400
申请日：2013-05-07
申请人： Forschungsverbund Berlin E.V.
发明人： Oliver Hilt , Rimma Zhytnytska , Hans-Joachim Würfl
IPC分类号： H01L29/02
CPC分类号： H01L29/78 , H01L29/06 , H01L29/2003 , H01L29/66462 , H01L29/7787 , H01L29/861
摘要： This invention relates to a semiconductor layer structure. The semiconductor layer structure described includes a substrate and a buffer layer deposited onto the substrate. The semiconductor layer structure is characterized in that a drain voltage threshold lower than the breakdown voltage threshold is determined by isolating ions that are selectively implanted in just one region of the substrate into the substrate, wherein charge can dissipate from the one contact through the buffer layer towards a substrate region without isolating ions, if the one potential deviates from the other at least by the drain voltage threshold, and wherein the substrate region without isolating ions is located underneath the one contact. The semiconductor layer structure described allows dissipation of currents induced by induction in blocking active structures without damaging the active structures.
摘要翻译：本发明涉及半导体层结构。所述的半导体层结构包括衬底和沉积在衬底上的缓冲层。半导体层结构的特征在于，通过将选择性地植入衬底的一个区域中的离子分离到衬底中来确定低于击穿电压阈值的漏极电压阈值，其中电荷可以通过缓冲层从一个触点消散如果一个电位至少与漏极电压阈值相离，则衬底区域不隔离离子，并且其中不隔离离子的衬底区域位于一个触点下方。所描述的半导体层结构允许在阻挡有源结构的情况下感应诱导的电流的耗散而不损坏有源结构。

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