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51. 发明申请

US20050205402A1 Illuminated vehicle remote entry device 失效
公开(公告)号：US20050205402A1
公开(公告)日：2005-09-22
申请号：US10802307
申请日：2004-03-17
申请人： James Wright , Leonard Pagano
发明人： James Wright , Leonard Pagano
IPC分类号： B60R25/10 , G07C9/00 , G09G5/00 , H01H9/00 , H01H9/02 , H01H9/18 , H04M1/00 , H05K7/02
CPC分类号： G07C9/00944 , G07C2009/00222 , H01H9/0235 , H01H9/182 , H01H2009/186 , Y10S345/905
摘要： A remote keyless entry electroluminiescent (EL) device includes at least one depressible button segment for activating a vehicle function. The entry device includes an upper housing with at least one aperture in the upper housing. An EL film is integral to the upper housing for illuminating at least one display area. A printed circuit board is disposed under the upper housing. An electrical contact is provided for supplying a power source from the printed circuit board to the EL film for illumination. A lower housing is adjoined to the upper housing, the upper housing and the lower housing encasing the printed circuit board wherein the EL film is in-molded as part of the upper housing for forming a single component.

52. 发明申请

US20050032836A1 Aripiprazole, olanzapine and haloperidol pamoate salts 有权
标题翻译：阿立哌唑，奥氮平和氟哌啶醇双羟萘酸盐
公开(公告)号：US20050032836A1
公开(公告)日：2005-02-10
申请号：US10635232
申请日：2003-08-06
申请人： Kristyn Greco , James Wright
发明人： Kristyn Greco , James Wright
IPC分类号： A61K31/445 , C07D211/52 , C07D211/54
CPC分类号： C07D211/52 , A61K31/445
摘要： The invention relates to the discovery that pamoate salts of haloperidol and aripiprazole result in a good to superior long acting and/or extended release profile. Thus, in one aspect of the invention, the invention includes pamoate salts of haloperidol or aripiprazole. Preferably, the pamoate salt is characterized by a ratio of haloperidol to pamoate of 1:1 or 2:1. The pamoate salt can be crystalline, such as a needle or a dense crystal, such as described in the Figures. The invention further relates to methods of treating an individual in need thereof comprising administering a pharmaceutical composition comprising a pamoate salt of haloperidol and aripiprazole.
摘要翻译：本发明涉及氟哌啶醇和阿立哌唑的双羟萘酸盐产生优异的长效和/或延长释放特征的发现。因此，在本发明的一个方面，本发明包括氟哌啶醇或阿立哌唑的双羟萘酸盐。优选地，双羟萘酸盐的特征在于氟哌啶醇与双羟萘酸的比例为1:1或2:1。双羟萘酸盐可以是结晶的，例如针或致密晶体，如图中所述。本发明还涉及治疗有需要的个体的方法，其包括施用包含氟哌啶醇和阿立哌唑的双羟萘酸盐的药物组合物。

53. 发明授权

US4077577A Non-stressed, high strength, cement-containing pipe and its production 失效
标题翻译：无应力，高强度，含水泥管及其生产
公开(公告)号：US4077577A
公开(公告)日：1978-03-07
申请号：US655189
申请日：1976-02-04
申请人： James Wright
发明人： James Wright
IPC分类号： B28B21/48 , B28B21/56 , B28B21/62 , F16L9/08 , F16L9/14 , F16L9/16 , B65H81/00
CPC分类号： B28B21/56 , B28B21/48 , B28B21/62 , F16L9/08 , F16L9/14 , F16L9/16
摘要： Non-stressed, high strength, substantially inflexible, rigid, cement-containing pipe, for example, asbestos-cement pipe well adapted as high pressure water pipe, comprising a tubular article body of spirally wound up layers of asbestos-cement, and a plurality of helical windings of a continuous filament of an aromatic polyamide fiber known and obtainable as KEVLAR aramid fiber about one or more of the asbestos-cement layers within the interior of the pipe without being stretched and without being in tension. The aromatic polyamide fiber of the continuous filament is of high tensile strength of about 390,000 psi or higher and a low elongation capability of no more than 7%, and the continuous filament of the belical windings is maintained about the cement-containing composition within the interior of the pipe without being stretched and without being in tension. Non-stressed, high strength concrete pipe is also embodied in the invention. The outer exposed main surface of the pipe is usually free or substantially free of the continuous filament.
摘要翻译：无应力，高强度，基本不弯曲，刚性的含水泥管，例如适用于高压水管的石棉 - 水泥管，包括石棉 - 水泥螺旋卷绕的管状物体，以及多个芳族聚酰胺纤维的连续长丝的螺旋绕组，其已知和可作为KEVLAR芳族聚酰胺纤维获得，围绕管内部的一个或多个石棉 - 水泥层而不被拉伸并且不处于张力。连续长丝的芳族聚酰胺纤维具有约390,000psi或更高的高拉伸强度和不超过7％的低伸长能力，并且围绕在内部的含水泥组合物保持连续细丝的管道，没有被拉伸而没有紧张。本发明还体现了非应力高强度混凝土管。管的外露的主表面通常是自由的或基本上没有连续细丝。

54. 发明授权

US09393310B2 Drug loaded polymeric nanoparticles and methods of making and using same 有权
公开(公告)号：US09393310B2
公开(公告)日：2016-07-19
申请号：US13478691
申请日：2012-05-23
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K9/14 , A61K47/34 , A61K9/10 , A61K9/19 , A61K9/51 , A61K31/337 , A61K31/436 , A61K31/475 , A61K47/48 , B82Y5/00 , A61J3/00 , A61K31/4355 , A61K31/437 , A61K31/704 , A61K31/7068 , A61K9/16 , C07C59/08
CPC分类号： A61K47/34 , A61J3/00 , A61K9/10 , A61K9/107 , A61K9/1647 , A61K9/19 , A61K9/5146 , A61K9/5153 , A61K31/337 , A61K31/4355 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/475 , A61K31/704 , A61K31/7068 , A61K47/6915 , A61K47/6925 , A61K47/6937 , B82Y5/00 , C07C59/08 , Y10S977/773
摘要： The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.

55. 发明授权

US08757924B2 Thermatic torpedo for reinstatement materials 有权
标题翻译：用于恢复材料的鱼雷鱼雷
公开(公告)号：US08757924B2
公开(公告)日：2014-06-24
申请号：US13824347
申请日：2011-10-16
申请人： James Wright
发明人： James Wright
IPC分类号： E01C19/46 , E01C19/10
CPC分类号： E01C19/1036 , E01C19/08 , E01C19/46 , E01C19/466
摘要： A thermic torpedo for preparing and delivering reinstatement materials has an internal chamber defining at least one compartment for containing graded aggregate and a second compartment for containing a stabilising agent, an external skin for insulating the contents of said internal chamber, a cap or lid for securely containing the contents of the torpedo in which is located at least one telescopic probe which can be driven through the compartments to heat and/or mix the contents thereof and at least one aperture through which the reinstatement materials may be expelled for delivery to a work site.
摘要翻译：用于制备和递送复原材料的热鱼雷具有限定至少一个隔室的内部腔室，用于容纳分级聚集体和用于容纳稳定剂的第二隔室，用于绝缘所述内部室的内容物的外部皮肤，用于安全地盖住盖子或盖子包含鱼雷的内容物，其中位于至少一个伸缩探头上，该探头可以被驱动穿过隔室以加热和/或混合其内容物和至少一个孔，复原材料可以通过该孔径排出以输送到工作地点。

56. 发明申请

US20120276162A1 Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same 有权
公开(公告)号：US20120276162A1
公开(公告)日：2012-11-01
申请号：US13478691
申请日：2012-05-23
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K47/32 , A61K31/475 , A61K9/14 , A61P35/00 , A61K31/337 , A61K31/436 , B82Y5/00
CPC分类号： A61K47/34 , A61J3/00 , A61K9/10 , A61K9/107 , A61K9/1647 , A61K9/19 , A61K9/5146 , A61K9/5153 , A61K31/337 , A61K31/4355 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/475 , A61K31/704 , A61K31/7068 , A61K47/6915 , A61K47/6925 , A61K47/6937 , B82Y5/00 , C07C59/08 , Y10S977/773
摘要： The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.

57. 发明授权

US08211473B2 Stable formulations for lyophilizing therapeutic particles 有权
标题翻译：用于冻干治疗颗粒的稳定制剂
公开(公告)号：US08211473B2
公开(公告)日：2012-07-03
申请号：US13253443
申请日：2011-10-05
申请人： Greg Troiano , Young-Ho Song , Stephen E. Zale , James Wright , Christina Van Geen Hoven
发明人： Greg Troiano , Young-Ho Song , Stephen E. Zale , James Wright , Christina Van Geen Hoven
IPC分类号： A61K31/724 , A61K47/40 , A61K47/30 , A61K9/14 , A61K9/19
CPC分类号： A61K31/337 , A61K9/0019 , A61K9/16 , A61K9/19 , A61K9/5123 , A61K9/5153 , A61K9/5161 , A61K9/5192 , A61K31/335 , A61K47/26 , A61K47/34 , A61K47/40 , C08G63/664 , Y10S977/906
摘要： The present disclosure generally relates to lyophilized pharmaceutical compositions comprising polymeric nanoparticles which, upon reconstitution, have low levels of greater than 10 micron size particles. Other aspects of the invention include methods of making such nanoparticles.
摘要翻译：本公开一般涉及包含聚合物纳米颗粒的冻干药物组合物，其在重构时具有低水平的大于10微米尺寸的颗粒。本发明的其它方面包括制备这种纳米颗粒的方法。

58. 发明申请

US20120140790A1 Therapeutic Polymeric Nanoparticle Compositions with High Glass Transition Termperature or High Molecular Weight Copolymers 有权
标题翻译：具有高玻璃化转变温度或高分子量共聚物的聚合物纳米粒子组合物
公开(公告)号：US20120140790A1
公开(公告)日：2012-06-07
申请号：US13372036
申请日：2012-02-13
申请人： Mir M. Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Tina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh C. Campbell
发明人： Mir M. Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Tina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh C. Campbell
IPC分类号： G01N25/20 , G01K17/00
CPC分类号： G01N25/4866 , A61K9/0019 , A61K9/146 , A61K9/5153 , A61K31/00 , A61K31/337 , A61K31/427 , A61K31/436 , A61K31/475 , A61K31/573 , A61K31/58 , A61K31/585 , A61K31/69 , A61K47/34
摘要： The present disclosure relates in part to pharmaceutical compositions comprising polymeric nanoparticles having certain glass transition temperatures. Other aspects of the invention include methods of making such nanoparticles.
摘要翻译：本公开部分涉及包含具有某些玻璃化转变温度的聚合物纳米颗粒的药物组合物。本发明的其它方面包括制备这种纳米颗粒的方法。

59. 发明授权

US07754659B2 Reducing flow-back in well treating materials 有权
标题翻译：在井处理材料中减少回流
公开(公告)号：US07754659B2
公开(公告)日：2010-07-13
申请号：US11803688
申请日：2007-05-15
申请人： Richard Rediger , Michael J. Aron , James Wright
发明人： Richard Rediger , Michael J. Aron , James Wright
IPC分类号： C09K8/74 , E21B43/267
CPC分类号： E21B43/267 , C09K8/805
摘要： A composite proppant having a proppant substrate such as a porous ceramic or silica sand coated with magnetic particles and a method of propping a subterranean formation using a composition consisting essentially of the composite proppant.
摘要翻译：具有支撑剂底物的复合支撑剂，例如多孔陶瓷或涂有磁性颗粒的硅砂，以及使用基本上由复合支撑剂组成的组合物来支撑地层的方法。

60. 发明申请

US20100104655A1 Therapeutic Polymeric Nanoparticles Comprising Vinca Alkaloids and Methods of Making and Using Same 有权
标题翻译：包含长春花碱生物碱的治疗性聚合物纳米颗粒及其制备和使用方法
公开(公告)号：US20100104655A1
公开(公告)日：2010-04-29
申请号：US12485467
申请日：2009-06-16
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K9/14 , A61K47/34 , A61K31/55 , A61K31/4745 , A61P35/00
CPC分类号： A61K9/1647 , A61K9/14 , A61K9/1694 , A61K9/19 , A61K9/5153 , A61K31/4745 , A61K31/475 , A61K31/55 , A61K47/26
摘要： The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer.
摘要翻译：本公开一般涉及治疗性纳米颗粒。本文公开的示例性纳米颗粒可包括约1至约20重量％的长春花生物碱; 和约50至约99重量％的生物相容性聚合物。

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