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    • 51. 发明申请
    • Tissue Repair Suture Plates and Methods of Use
    • 组织修复缝合板和使用方法
    • US20140005729A1
    • 2014-01-02
    • US13537670
    • 2012-06-29
    • Kristian DiMatteo
    • Kristian DiMatteo
    • A61B17/88A61B17/04A61B17/80
    • A61B17/0401A61B17/8052A61B17/8085A61B17/809A61B2017/00004A61B2017/0409A61B2017/044A61B2017/0446
    • Tissue repair suture plates and methods of use are provided which can, in general, allow soft tissue to be secured to bone. In one embodiment, a tissue repair suture plate can include a plurality of openings formed therethrough that can each be configured to have one or more sutures passed therethrough. Each of the sutures can be configured to be coupled to a soft tissue to be positioned against bone for healing thereagainst such that the soft tissue can have multiple sutures coupled thereto at different areas thereof. One or more bone fixation elements can be coupled to the plate and can be configured to attach the plate to the bone. The plate can be configured to move between a first configuration in which the plate has a first maximum length and a second configuration in which the plate has a second, greater maximum length.
    • 提供组织修复缝合板和使用方法,其通常可以使软组织固定在骨上。 在一个实施例中,组织修复缝合板可以包括穿过其中形成的多个开口,每个开口可被配置成具有穿过其中的一个或多个缝合线。 每个缝合线可以被配置为联接到软组织以被定位成抵靠骨头,以在其上进行愈合,使得软组织可以在其不同区域处与多个缝合线耦合。 一个或多个骨固定元件可以联接到板上并且可以被配置成将板附接到骨。 板可以被配置为在其中板具有第一最大长度的第一构造和其中板具有第二更大最大长度的第二构造之间移动。
    • 52. 发明授权
    • Methods and devices for delivering and affixing tissue scaffolds
    • 用于递送和固定组织支架的方法和装置
    • US08241298B2
    • 2012-08-14
    • US12412499
    • 2009-03-27
    • Mehmet Z. SengunKristian DiMatteo
    • Mehmet Z. SengunKristian DiMatteo
    • A61F2/84
    • A61F2/4618A61F2002/30766A61F2002/4627
    • Methods and devices are provided for delivering and affixing tissue replacements. In one embodiment, a tissue scaffold can be delivered into a patient through a cannula to a cavity formed at a defect site in tissue, e.g., cartilage. A delivery shaft can be used to deliver the scaffold through the cannula, and a loading device can help load the scaffold onto the delivery shaft. A delivery guide device can position and temporarily hold the scaffold within the cavity. The delivery guide device can guide one or more surgical instruments to the scaffold to affix the scaffold within the cavity, e.g., to bone underlying the scaffold, using at least one securing mechanism.
    • 提供了用于递送和贴附组织替代物的方法和装置。 在一个实施例中,组织支架可以通过套管递送到患者体内,形成在组织例如软骨中的缺损部位。 输送轴可用于通过套管递送支架,并且装载装置可以帮助将支架装载到输送轴上。 输送引导装置可以将支架放置并暂时保持在腔内。 输送引导装置可以使用至少一个固定机构将一个或多个外科器械引导至支架以将支架固定在腔内,例如骨架下面的骨骼上。
    • 55. 发明授权
    • Tissue extraction and collection device
    • 组织提取和收集装置
    • US08034003B2
    • 2011-10-11
    • US12056637
    • 2008-03-27
    • Robert S. PesceShelby CookKristian DiMatteoKevin RanucciRobert Boock
    • Robert S. PesceShelby CookKristian DiMatteoKevin RanucciRobert Boock
    • A61B10/00
    • A61B10/025A61B10/0096A61B10/0266A61B10/0283A61B17/1635A61B17/32002A61B2017/320064A61B2090/0807
    • Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
    • 公开了用于提取和收集组织的方法和装置,其可以用于组织工程和移植应用中。 在一个实施例中,装置可以包括外管。 旋转轴可以设置在外管内,可以具有形成在其远端上的组织收集尖端,组织收集尖端有效地在旋转时切除组织。 可以包括组织收集装置以接收和收集切除的组织,并且组织收集装置可以指示其中收集的组织的量。 例如,组织收集装置可以包括收集切除的组织的应变元件和用于评估收集的组织的量的指示器。 在一些实施例中,组织收集装置可以平移以指示收集的组织的量。 在许多情况下,本文公开的装置可以包括适于驱动组织收集尖端的驱动机构,使得尖端切除软组织,但是当接触骨骼时(或者在接触骨骼之后不久)停止。 在一些实施方案中,组织采集尖端可有效地切除活组织样品,使得样品可以显示出所需比例的活细胞。 此外,在一些实施例中,组织采集尖端可以用落在一定尺寸范围内的组织颗粒来切除组织样本。
    • 57. 发明申请
    • VARIABLE LENGTH ENDOVASCULAR GRAFT PROSTHESIS ADAPTED TO PREVENT ENDOLEAKS
    • 可变长度血管内皮细胞肿瘤适应于预防内分泌
    • US20100256745A1
    • 2010-10-07
    • US12820777
    • 2010-06-22
    • Kristian DiMatteoRobert Thistle
    • Kristian DiMatteoRobert Thistle
    • A61F2/82
    • A61F2/06A61F2/064A61F2250/006A61F2250/0065
    • A variable length endovascular prosthesis to prevent endoleaks includes a substantially tubular first graft member having an interior surface, an exterior surface, and an open end, and a substantially tubular second graft member engaged coaxially within the first graft member, the second graft member having a proximal end. The prosthesis further includes a substantially tubular fluid-tight connecting member attached at one end to the first graft member and attached at another end to the second graft member, where the connecting member is axially compressible and expandable to facilitate engagement of the proximal end of the second graft member within the first graft member while maintaining a seal between the proximal end of the second graft member and the open end of the first graft member.
    • 用于防止内漏的可变长度的血管内假体包括具有内表面,外表面和开口端的基本上管状的第一移植件,以及同轴地接合在第一移植件内的基本管状的第二移植件,第二移植件具有 近端。 所述假体还包括基本上管状的流体密封连接构件,所述连接构件的一端连接到所述第一移植构件,并且在另一端附接到所述第二移植构件,其中所述连接构件是轴向可压缩且可扩张的,以便于接合所述第二移植构件的近端 第二移植物件,同时保持第二移植物件的近端和第一移植物件的开口端之间的密封。