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51. 发明申请

US20050143427A1 [B]-fused bicyclic proline derivatives and their use for treating arthritic conditions 审中-公开
标题翻译： [B] - 双环脯氨酸衍生物及其用于治疗关节炎病症的用途
公开(公告)号：US20050143427A1
公开(公告)日：2005-06-30
申请号：US10822389
申请日：2004-04-12
申请人： Nicole Barvian , Cleo Connolly , Peter Guzzo , James Hamby , James Hicks , Matthew Johnson , Van-Duc Le , Lorna Mitchell , William Roark
发明人： Nicole Barvian , Cleo Connolly , Peter Guzzo , James Hamby , James Hicks , Matthew Johnson , Van-Duc Le , Lorna Mitchell , William Roark
IPC分类号： A61P19/00 , C07D209/12 , C07D209/14 , C07D403/04 , C07D413/04 , C07D417/02 , C07D495/04 , A61K31/433 , A61K31/4245 , C07D413/02
CPC分类号： C07D495/04 , C07D209/12 , C07D209/14 , C07D403/04 , C07D413/04 , C07D417/02
摘要： This invention relates to a compound which is [b]-fused bicyclic proline derivative, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising the compound or the salt thereof, and methods of treating diseases, including, but not limited to, methods of preventing or inhibiting joint cartilage damage and preventing or treating diseases characterized by joint cartilage damage, joint inflammation, or joint pain. The [b]-fused bicyclic proline derivatives are compounds of Formula I as described above. Diseases characterized by joint cartilage damage or joint pain include, for example, osteoarthritis and rheumatoid arthritis. Rheumatoid arthritis is also characterized by joint inflammation. This invention also relates to methods of synthesizing and preparing the [b]-fused bicyclic proline derivatives, or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及[b]双环脯氨酸衍生物或其药学上可接受的盐的化合物; 包含该化合物或其盐的药物组合物和治疗疾病的方法，包括但不限于预防或抑制关节软骨损伤和预防或治疗以关节软骨损伤，关节炎症或关节疼痛为特征的疾病的方法。 [b]引发的双环脯氨酸衍生物是如上所述的式I化合物。以关节软骨损伤或关节疼痛为特征的疾病包括例如骨关节炎和类风湿性关节炎。类风湿性关节炎的特征还在于关节炎。本发明还涉及合成和制备[b] - 双环脯氨酸衍生物或其药学上可接受的盐的方法。

52. 发明申请

US20050005342A1 CUT AWAY VEST 有权
标题翻译：切割外套
公开(公告)号：US20050005342A1
公开(公告)日：2005-01-13
申请号：US10604283
申请日：2003-07-08
申请人： Matthew Johnson
发明人： Matthew Johnson
IPC分类号： A45F5/02 , F41H1/02 , A41D1/04
CPC分类号： F41H1/02 , A41D2400/44 , A45F5/02 , A45F2003/144
摘要： A vest is provided that may be quickly and easily removed from a wearer of the vest. The vest includes a waist belt, a cummerbund, and shoulder straps which may be easily released from the vest by the use of a flexible retainer in cooperation with a connector device secures the waist belt, cummerbund and shoulder straps to the vest in a releasable manner. A cable portion of the retainer moves in a generally straight line except for accommodating curved portions of the body of the wearer. An accessory pouch may also be provided which uses a strap and loop arrangement on the vest and pouch to attach the accessory pouch to the vest.
摘要翻译：提供背心，其可以快速且容易地从背心的穿着者去除。该背心包括腰带，腰带和肩带，其可以通过使用与连接器装置配合的柔性保持器容易地从背心上脱离，从而以可释放的方式将腰带，腰带和肩带固定到背心上。除了容纳穿着者身体的弯曲部分之外，保持器的电缆部分以一般的直线运动。还可以提供附件袋，其使用背心和袋上的带和环布置将附件袋附接到背心。

53. 发明申请

US20180046352A1 VIRTUAL CURSOR MOVEMENT 审中-公开
公开(公告)号：US20180046352A1
公开(公告)日：2018-02-15
申请号：US15232607
申请日：2016-08-09
申请人： Matthew Johnson , Aaron Mackay Burns , Donna Long , Benjamin John Sugden , Bryant Hawthorne
发明人： Matthew Johnson , Aaron Mackay Burns , Donna Long , Benjamin John Sugden , Bryant Hawthorne
IPC分类号： G06F3/0481 , G06T19/00
CPC分类号： G06F3/04815 , G06F1/163 , G06F3/011 , G06F3/04812 , G06T19/006
摘要： A method for moving a virtual cursor on a virtual reality computing device including a display comprises presenting a virtual cursor at a first screen-space position that occludes a world-space position of a first object, the virtual cursor having a first world-space position based on the first screen-space position and the world-space position of the first object. Based on receiving an input, the method includes moving the virtual cursor from the first screen-space position to a second screen-space position that occludes a world-space position of a second object, the virtual cursor having a second world-space position based on the second screen-space position and the world-space position of the second object. While the virtual cursor is presented at an intermediate screen-space position, the method includes assigning an intermediate world-space position based on the intermediate screen-space position and simulated attractive forces for each of the first and second objects.

54. 发明授权

US09441542B2 Ultrasonic water atomization system for gas turbine inlet cooling and wet compression 有权
标题翻译：用于燃气轮机入口冷却和湿压缩的超声波水雾化系统
公开(公告)号：US09441542B2
公开(公告)日：2016-09-13
申请号：US13236712
申请日：2011-09-20
申请人： Jianmin Zhang , Brad Kippel , James Tomey , Matthew Johnson
发明人： Jianmin Zhang , Brad Kippel , James Tomey , Matthew Johnson
IPC分类号： F02C7/14 , F02C7/143 , B05B17/06
CPC分类号： F02C7/1435 , B05B17/0615
摘要： The present application provides an inlet air cooling system for cooling a flow air in a gas turbine engine. The inlet air cooling system may include an inlet filter house, a transition piece, an inlet duct, and an inlet ultrasonic water atomization system positioned about the inlet filter house, the transition piece, or the inlet duct to cool the flow of air.
摘要翻译：本申请提供了一种用于冷却燃气涡轮发动机中的流动空气的入口空气冷却系统。入口空气冷却系统可以包括入口过滤器室，过渡件，入口管道和入口超声波水雾化系统，其围绕入口过滤器室，过渡件或入口管道定位，以冷却空气流。

55. 发明申请

US20150238364A1 EARRING ATTACHABLE EARPLUG 审中-公开
标题翻译：耳环连接耳环
公开(公告)号：US20150238364A1
公开(公告)日：2015-08-27
申请号：US14187529
申请日：2014-02-24
申请人： Matthew Johnson , Christine Beavis
发明人： Matthew Johnson , Christine Beavis
IPC分类号： A61F11/12
CPC分类号： A61F11/12 , A44C7/002 , A44C7/003 , A44C15/003 , A61F2220/0016 , A61F2220/0033 , A61F2230/0069 , A61F2250/0029
摘要： A hearing protection device is disclosed. The hearing protection device is comprised of an assembly consisting of an earplug attached to a first end of a flexible leash and an earring attachment barrel attached at a second or distal end of the same flexible leash. In use, the attachment barrel may be easily inserted onto a post or hook of any standard earring wherein the earplug may be allowed to dangle from the earring when worn. When the wearer requires sound suppression, he/she simply inserts the earplug into their ear canal without removing the earplug assembly from their earring. The earplug assembly is easily removed from the ear canal by the wearer simply tugging on the flexible leash. The earplug assembly may be removed from the earrings, and may be washed and reused over and over again or used with another pair of earrings.
摘要翻译：公开了一种听力保护装置。听力保护装置包括由附接到柔性皮带的第一端的耳塞和附接在相同柔性皮带的第二或远端处的耳环连接筒组成的组件。在使用中，附件筒可以容易地插入到任何标准耳环的柱子或钩子上，其中当佩戴时耳塞可能被耳环悬垂。当佩戴者需要声音抑制时，他/她只需将耳塞插入耳道，而不会从耳环中移除耳塞组件。耳塞组件可以方便地从耳道上被穿戴者简单地拉在柔性皮带上。耳塞组件可以从耳环上移除，并且可以一遍又一遍地洗涤和重复使用或与另一对耳环一起使用。

56. 发明授权

US08972050B2 Pharmaceutical dispensing systems and graphical user interfaces associated with same 有权
标题翻译：药物分配系统和与之相关的图形用户界面
公开(公告)号：US08972050B2
公开(公告)日：2015-03-03
申请号：US12466717
申请日：2009-05-15
申请人： Matthew Johnson , Harold Lindsey , Megan Dunigan , Justin Lallinger , John Kirk Hammond, Jr.
发明人： Matthew Johnson , Harold Lindsey , Megan Dunigan , Justin Lallinger , John Kirk Hammond, Jr.
IPC分类号： G06F17/00 , G06F3/01 , G07F11/00 , G06F19/00 , G07F11/30 , G07F11/44 , G07F11/62 , G07F17/00
CPC分类号： G07F11/002 , G06F19/00 , G06F19/3462 , G07F11/30 , G07F11/44 , G07F11/62 , G07F17/0092
摘要： A pharmaceutical dispensing system includes a frame having first and second opposed sides, a plurality of cells configured to house pharmaceutical pills, a first touch screen display on the frame first side, and a second touch screen display on the frame second side. The pharmaceutical dispensing system includes a processor and memory coupled thereto. A computer program resides in the memory and is executable by the processor for displaying a cell inventory graphical user interface (GUI) within the first touch screen display, and a prescription order processing GUI within the second touch screen display that include status information about a prescription order at a respective stage of completion by the pharmaceutical dispensing system.
摘要翻译：药剂分配系统包括具有第一和第二相对侧的框架，多个单元，其被配置为容纳药丸，第一触摸屏显示在框架第一侧上，第二触摸屏显示在框架第二侧。药物分配系统包括与其耦合的处理器和存储器。计算机程序驻留在存储器中并且可由处理器执行以在第一触摸屏显示内显示单元格库存图形用户界面（GUI），以及第二触摸屏显示内的处方订单处理GUI，其包括关于处方的状态信息在药物分配系统的各个阶段完成。

57. 发明授权

US08954201B2 Realization of energy savings potential through feedback 有权
标题翻译：通过反馈实现节能潜力
公开(公告)号：US08954201B2
公开(公告)日：2015-02-10
申请号：US13486430
申请日：2012-06-01
申请人： Michele Tepper , Seth Frader-Thompson , Matthew Johnson
发明人： Michele Tepper , Seth Frader-Thompson , Matthew Johnson
IPC分类号： G05D17/00 , G05B15/00
CPC分类号： F24F11/006 , F24F11/30 , F24F11/62 , G05B15/00 , G05B15/02 , G05B2219/2614 , Y02T90/168 , Y04S30/12 , Y10S715/961
摘要： Feedback is provided to a user based on a setting for a set of energy consuming devices. While a user modifies a thermostat's schedule or provides user commands to adjust a setting for the set of energy consuming devices, a user interface component generates feedback to the consumer in response to an adjusted setting based on a condition for a predetermined function. A positive feedback component generates a positive feedback, such as a positive image in the user interface if the setting meets or exceeds a recommended performance metric for an operational parameter for the set of energy consuming devices. A negative feedback component generates a negative feedback, such as a negative image if the setting meets or exceeds a second condition, such as a discouraged performance metric.
摘要翻译：基于一组能量消耗装置的设置向用户提供反馈。当用户修改恒温器的调度或提供用户命令以调整该组能量消耗设备的设置时，用户界面组件响应于基于预定功能的条件的调整的设置而向消费者生成反馈。正反馈组件产生正反馈，例如，如果设置满足或超过用于该组能量消耗设备的操作参数的推荐性能度量，则该用户界面中的正图像。负反馈分量产生负反馈，例如如果设置满足或超过第二条件（例如不鼓励的性能度量）的负图像。

58. 发明授权

US08891338B2 Measuring the accuracy of an endpoint clock from a remote device 有权
标题翻译：从远程设备测量端点时钟的精度
公开(公告)号：US08891338B2
公开(公告)日：2014-11-18
申请号：US12362330
申请日：2009-01-29
申请人： Matthew Johnson , Mark Cornwall
发明人： Matthew Johnson , Mark Cornwall
IPC分类号： H04J3/06 , G04C11/04 , G01D4/00
CPC分类号： G04C11/04 , G01D4/004 , Y02B90/242 , Y04S20/322
摘要： Packet formats and associated metering infrastructure for filtering meter reading data that is being transmitted by utility meters are disclosed. In one embodiment, a method is provided of measuring the accuracy of an endpoint clock, such as a utility meter clock, from a remote device configured to capture transmissions that originate from the utility meter. Generally, the method includes synchronizing the time maintained by the utility meter with the time maintained by the remote device. The method receives and decodes a packet that includes a time stamp provided by the utility meter. Then, the method calculates the extent of the inaccuracy of the time stamp in the received packet and determines whether the extent of the inaccuracy satisfies a predetermined threshold.
摘要翻译：公开了用于过滤由电表进行传输的抄表数据的数据包格式和相关的计量基础设施。在一个实施例中，提供了一种从被配置为捕获源自公用事业计量表的传输的远程设备测量端点时钟（诸如公用事业计时钟）的精度的方法。通常，该方法包括将由公用事业计算机维护的时间与由远程设备维护的时间同步。该方法接收并解码包含由公用事业计量表提供的时间戳的分组。然后，该方法计算接收到的分组中的时间戳的不准确程度，并确定不准确度的程度是否满足预定阈值。

59. 发明申请

US20140200460A1 REAL-TIME PHYSIOLOGICAL CHARACTERISTIC DETECTION BASED ON REFLECTED COMPONENTS OF LIGHT 审中-公开
标题翻译：基于反射光的组件的实时生理特征检测
公开(公告)号：US20140200460A1
公开(公告)日：2014-07-17
申请号：US13967317
申请日：2013-08-14
申请人： Matthew Johnson , Aza Raskin
发明人： Matthew Johnson , Aza Raskin
IPC分类号： A61B5/00 , A61B5/024
CPC分类号： A61B5/0077 , A61B5/024 , A61B5/02416 , A61B5/02438 , A61B5/6803 , A61B5/681 , A61B5/7225 , A61B5/726
摘要： Embodiments relate generally to electrical and electronic hardware, computer software, wired and wireless network communications, and wearable/mobile computing devices configured to facilitate health and wellness monitoring and maintenance. More specifically, disclosed are systems, components and methods to detect physiological characteristics, such as heart rate, of an organism in real-time based on components of light. In various embodiments, a method can include receiving color channel signals including imagery data generated by, for example, an image capture device. A linear combination of the color channel signals can form a combined color channel signal. The method also can include transforming continuously the combined color channel signal to establish local maxima associated with multiple scales. Further, portions of time associated with the local maxima can be identified and data signal representing a physiological characteristic can be generated. A local maximum can indicate the presence of enhanced blood volume adjacent a tissue surface.
摘要翻译：实施例通常涉及电气和电子硬件，计算机软件，有线和无线网络通信以及被配置为促进健康和健康监测和维护的可穿戴/移动计算设备。更具体地，公开了基于光的组分实时地检测生物体的生理特征，例如心率的系统，组件和方法。在各种实施例中，一种方法可以包括接收彩色通道信号，包括由例如图像捕获装置产生的图像数据。颜色通道信号的线性组合可以形成组合的颜色通道信号。该方法还可以包括连续变换组合的彩色信道信号以建立与多个尺度相关联的局部最大值。此外，可以识别与局部最大值相关联的时间部分，并且可以生成表示生理特征的数据信号。局部最大值可以指示邻近组织表面存在增强的血液体积。

60. 发明申请

US20130222387A1 Event Data Visualization Tool 有权
标题翻译：事件数据可视化工具
公开(公告)号：US20130222387A1
公开(公告)日：2013-08-29
申请号：US13404784
申请日：2012-02-24
申请人： Jeffrey M. Bradshaw , Lawrence K. Bunch , Marco M. Carvalho , Thomas C. Eskridge , Paul J. Feltovich , Matthew Johnson
发明人： Jeffrey M. Bradshaw , Lawrence K. Bunch , Marco M. Carvalho , Thomas C. Eskridge , Paul J. Feltovich , Matthew Johnson
IPC分类号： G06T11/20
CPC分类号： G06T11/206
摘要： A method for visually depicting complex events. Software agents are preferably employed to assist the human operator by collecting, enriching, selecting, aggregating, and analyzing data so that patterns of interest can be visually flagged or otherwise emphasized in the visual display. Events are depicted as an “event flow” from a source surface to a destination surface. Intervening surfaces may also be defined. The point of origin on the source surface reveals some information about the event flow, as does the point of impact on the destination surface. The event flow may be mapped to one or more intervening surfaces in order to visually depict other characteristics of the event. The entire depiction is rendered in a simulated three-dimensional view. The user is preferably given the ability to pan, zoom, and reorient the vantage point from which the user “views” the depiction on the computer display.
摘要翻译：一种视觉描绘复杂事件的方法。软件代理优选地用于通过收集，丰富，选择，聚集和分析数据来帮助人类操作者，使得感兴趣的模式可以在视觉显示中被视觉地标记或以其它方式加强。事件被描绘为从源表面到目的地表面的“事件流”。还可以定义中间表面。源表面上的起点显示有关事件流的一些信息，以及对目标表面的影响点。事件流可以映射到一个或多个中间表面，以便可视地描绘事件的其他特征。整个描述在模拟的三维视图中呈现。用户优选地具有平移，缩放和重新定向用户在其上“查看”计算机显示器上的描绘的有利位置的能力。

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