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51. 发明申请

US20140364443A1 1,4-DIHYDRO-NAPHTHYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 有权
标题翻译： 1,4-二氢萘啶衍生物和药物组合物及其用途
公开(公告)号：US20140364443A1
公开(公告)日：2014-12-11
申请号：US14362735
申请日：2012-12-07
申请人： Rong Chen , Lin Feng , Zhengping Zhang , Fang Fang , Qingli Dong , Fulong Li , Lei Wang , Yao Hua , Shibao Yang , Peng Wang
发明人： Rong Chen , Lin Feng , Zhengping Zhang , Fang Fang , Qingli Dong , Fulong Li , Lei Wang , Yao Hua , Shibao Yang , Peng Wang
IPC分类号： C07D495/14 , C07D471/14 , C07D471/04
CPC分类号： C07D495/14 , C07D471/04 , C07D471/12 , C07D471/14 , C07D491/14
摘要： Disclosed are 1,4-dihydro-naphthyridine derivatives and pharmaceutical composition and uses thereof. The 1,4-dihydro-naphthyridine derivatives are a compound capable of inhibiting acetylcholinesterase activity and preventing extracellular calcium from flowing into a cell via a calcium channel, i.e., having a dual-activity, which are of potential importance as a pharmaceutical and can be used to prepare the drugs for treating cardiovascular diseases, cerebrovascular diseases and dementia.
摘要翻译：公开了1,4-二氢 - 萘啶衍生物及其药物组合物及其用途。 1,4-二氢 - 萘啶衍生物是能够抑制乙酰胆碱酯酶活性并防止细胞外钙通过钙通道流入细胞的化合物，即具有作为药物具有潜在重要性的双重活性，可以是用于制备治疗心血管疾病，脑血管疾病和痴呆症的药物。

52. 发明授权

US08881045B2 Method and apparatus for generating prompt information of a mobile terminal 有权
标题翻译：用于产生移动终端的提示信息的方法和装置
公开(公告)号：US08881045B2
公开(公告)日：2014-11-04
申请号：US12562864
申请日：2009-09-18
申请人： Jian Yang , Guoqiao Chen , Lei Wang
发明人： Jian Yang , Guoqiao Chen , Lei Wang
IPC分类号： G06F3/00 , G11B27/34 , G11B27/034 , G11B27/10 , G11B27/30 , G11B27/32 , H04M19/04 , H04M1/725
CPC分类号： G11B27/34 , G11B27/034 , G11B27/105 , G11B27/3027 , G11B27/322 , H04M1/72558 , H04M19/04
摘要： A method and apparatus for generating prompt information of a mobile terminal are disclosed. The method includes: selecting a start point and an end point in a multimedia file; clipping a part of the multimedia file between the start point and the end point in the multimedia file; and encoding the clipped part of the multimedia file, and generating prompt information of the mobile terminal. An apparatuses for generating prompt information of a mobile terminal is also disclosed. Therefore, the present invention enables a user to control the generation of prompt information of a mobile terminal.
摘要翻译：公开了一种用于产生移动终端的提示信息的方法和装置。该方法包括：在多媒体文件中选择起始点和终点; 在多媒体文件的起始点和终点之间裁剪多媒体文件的一部分; 以及对所述多媒体文件的被剪辑部分进行编码，以及生成所述移动终端的提示信息。还公开了一种用于产生移动终端的提示信息的装置。因此，本发明使得用户能够控制移动终端的即时信息的产生。

53. 发明授权

US08798978B2 Methods to estimate downhole drilling vibration indices from surface measurement 有权
标题翻译：从表面测量估计井下钻孔振动指数的方法
公开(公告)号：US08798978B2
公开(公告)日：2014-08-05
申请号：US13386862
申请日：2010-08-06
申请人： Mehmet Deniz Ertas , Jeffrey R. Bailey , Damian N. Burch , Lei Wang , Paul E. Pastusek , Shankar Sundararaman
发明人： Mehmet Deniz Ertas , Jeffrey R. Bailey , Damian N. Burch , Lei Wang , Paul E. Pastusek , Shankar Sundararaman
IPC分类号： G06G7/48 , E21B45/00 , E21B44/00
CPC分类号： E21B44/00 , E21B45/00
摘要： Method to estimate severity of downhole vibration for a wellbore drill tool assembly, comprising: identifying a dataset comprising selected drill tool assembly parameters; selecting a reference downhole vibration index for the drill tool assembly; identifying a surface parameter and calculating a reference surface vibration attribute for the selected reference downhole vibration index; determining a surface vibration attribute derived from at least one surface measurement or observation obtained in a drilling operation, the determined surface vibration attribute corresponding to the identified surface parameter; and estimating a downhole vibration index by evaluating the determined surface vibration attribute with respect to the identified reference surface vibration attribute.
摘要翻译：一种用于估计井眼钻具组件的井下振动的严重性的方法，包括：识别包括所选择的钻具组件参数的数据集; 选择钻具组件的参考井下振动指数; 识别表面参数并计算所选参考井下振动指数的参考表面振动属性; 确定从在钻井操作中获得的至少一个表面测量或观察得出的表面振动属性，所确定的表面振动属性对应于所识别的表面参数; 以及通过相对于所识别的参考表面振动属性评估所确定的表面振动属性来估计井下振动指数。

54. 发明申请

US20140154220A1 Methods and Compositions for Improved Tissue Regeneration by Suppression of Interferon-Gamma and Tumor Necrosis Factor-Alpha 审中-公开
标题翻译：通过抑制干扰素 - γ和肿瘤坏死因子-α改善组织再生的方法和组合
公开(公告)号：US20140154220A1
公开(公告)日：2014-06-05
申请号：US14114070
申请日：2012-04-25
申请人： Songtao Shi , Yi Liu , Lei Wang
发明人： Songtao Shi , Yi Liu , Lei Wang
IPC分类号： A61K35/28 , A61K31/616
CPC分类号： A61K35/28 , A61K31/616 , A61K35/17 , A61K45/06 , A61L27/3834 , A61L27/54 , A61L2300/41 , A61K2300/00
摘要： The present invention discloses methods, compositions and devices for improving tissue regeneration by suppressing the effects of several proinflammatory cytokines such as TNF-α and IFN-γ. Compositions and devices of this invention will generally include one or more anti-inflammatory agent(s) capable of reducing the level of TNF-α, IFN-γ, or both. Methods for improving tissue regeneration in accordance with this invention will generally have the step of applying a composition or device of the invention to a site in need of the composition or device. Also disclosed are methods for forming composition and devices of the invention and pharmaceutical compositions comprising one or more anti-inflammatory agent(s) effective of inhibiting or reducing the levels of TNF-α, IFN-γ, or both.
摘要翻译：本发明公开了通过抑制TNF-α和IFN-γ等促炎细胞因子的作用来改善组织再生的方法，组合物和装置。本发明的组合物和装置通常包括能够降低TNF-α，IFN-γ或两者的水平的一种或多种抗炎剂。根据本发明的用于改善组织再生的方法通常具有将本发明的组合物或装置应用于需要组合物或装置的部位的步骤。还公开了用于形成本发明的组合物和装置的方法和包含一种或多种有效抑制或降低TNF-α，IFN-γ或两者的水平的抗炎药的药物组合物。

55. 发明授权

US08686179B2 Fluorinated aromatic bis(acyl)-containing compounds and polyesters prepared therefrom 有权
标题翻译：含氟芳香族双（酰基）的化合物和由其制备的聚酯
公开(公告)号：US08686179B2
公开(公告)日：2014-04-01
申请号：US13322217
申请日：2010-06-07
申请人： Yu Yang , Lei Wang , George G. I. Moore
发明人： Yu Yang , Lei Wang , George G. I. Moore
IPC分类号： C07C303/00
CPC分类号： C07C317/48 , C07C41/09 , C07C41/16 , C07C311/09 , C07C315/04 , C08G63/6856 , C08G63/6886 , C09D167/02 , C07C43/174
摘要： A fluorinated bis(acyl)-containing compound of Formula (I), where R1, Ar, L, R2, R3, Rf, n, p and q are as defined in the claims, and a fluorinated polyester formed from the fluorinated bis(acyl) compound are described. More particularly, the fluorinated bis(acyl) has an aromatic ring bonded to two acyl groups plus at least one third group that contains a perfluoroalkylsulfonamido group. The fluorinated polyesters formed from the fluorinated bis(acyl)-containing compound can be used to provide a low energy surface with a relatively low refractive index compared to many other polyesters. A method of preparing a monosubstituted-arylene compound of formula Rf1-L2-CH2—Ar2—CH2—W, where Ar2, Rf1, L2, R6 and W are as defined in the claims by reaction of a compound of formula Rf1-L2-H with a compound of formula W—CH2—Ar2—CH2—W.
摘要翻译：式（I）的含氟双（酰基）的化合物，其中R 1，Ar，L，R 2，R 3，R f，n，p和q如权利要求中所定义，和由氟化双酰基）化合物。更具体地，氟化双（酰基）具有键合到两个酰基加上含有全氟烷基磺酰氨基的至少三个基团的芳环。由含氟二（酰基）的化合物形成的氟化聚酯可以用于提供与许多其它聚酯相比折射率相对较低的低能量表面。制备式Rf1-L2-CH2-Ar2-CH2-W的单取代 - 亚芳基化合物的方法，其中Ar2，Rf1，L2，R6和W如权利要求中所定义，如式Rf1-L2- H与式W-CH 2 -Ar 2 -CH 2 -W的化合物反应。

56. 发明授权

US08642287B2 Cell-impedance sensors 有权
标题翻译：电池阻抗传感器
公开(公告)号：US08642287B2
公开(公告)日：2014-02-04
申请号：US12532992
申请日：2007-07-25
申请人： Lei Wang , Keith Mitchelson , He Wang , Jing Cheng
发明人： Lei Wang , Keith Mitchelson , He Wang , Jing Cheng
IPC分类号： C12Q1/02 , C12M1/34 , G06F7/60 , G06F17/50 , G01R27/08
CPC分类号： G01N27/06 , G01N27/221 , G01N33/48707 , G01N33/48728 , G01N33/5438
摘要： Methods and apparatus for designing and measuring a cell-electrode impedance sensor to detect chemical and biological samples, including biological cells. The method of designing a cell-electrode impedance sensor comprises: determining a cell free cell-electrode impedance and a cell-covered cell-electrode impedance; obtaining a sensor sensitivity of the cell-electrode impedance measurement system; and choosing one or more design parameters of the cell-electrode impedance sensor to maximize the sensor sensitivity. When the frequency of AC signal between electrodes ranges from 10 kHz to 40 kHz, the sensitivity of the sensor is maximized.
摘要翻译：用于设计和测量细胞电极阻抗传感器以检测包括生物细胞在内的化学和生物样品的方法和装置。设计电池电极阻抗传感器的方法包括：确定无电池的电池 - 电极阻抗和电池覆盖的电池 - 电极阻抗; 获得电池电极阻抗测量系统的传感器灵敏度; 并选择电池电极阻抗传感器的一个或多个设计参数以最大化传感器灵敏度。当电极间交流信号的频率范围为10 kHz至40 kHz时，传感器的灵敏度最大化。

57. 发明授权

US08627263B2 Gate configuration determination and selection from standard cell library 有权
标题翻译：门配置确定和选择从标准单元库
公开(公告)号：US08627263B2
公开(公告)日：2014-01-07
申请号：US13365989
申请日：2012-02-03
申请人： Thomas Buechner , Markus Buehler , Markus Olbrich , Philipp Panitz , Lei Wang
发明人： Thomas Buechner , Markus Buehler , Markus Olbrich , Philipp Panitz , Lei Wang
IPC分类号： G06F17/50
CPC分类号： G06F17/505 , G06F2217/08
摘要： A method comprises determining gate configuration from a standard cell library for optimizing behavior of a logic gate in an electronic circuit to be resized. The determining includes defining variables for the logic gate to be resized and defining nets influenced by the logic gate to be resized. The determining includes determining constraints relative to other logic gates in the electronic circuit affected by the logic gate to be resized and formulating objective function. The determining includes solving the objective function using a linear programming solver based on the defined variables and the determined constraints. The determining includes outputting solving of the objective function obtained by linear programming solver for further processing. The gate configuration is selected from the standard cell library for optimizing behavior of the logic gate to be resized based on solving of the objective function.
摘要翻译：一种方法包括从标准单元库确定门配置，以优化要调整大小的电子电路中的逻辑门的行为。确定包括定义要调整大小的逻辑门的变量，并定义受逻辑门影响的网络以进行调整大小。确定包括确定受到要调整大小的逻辑门影响的电子电路中的其他逻辑门的约束，并且制定目标函数。该确定包括使用线性规划求解器基于所定义的变量和确定的约束求解目标函数。确定包括输出由线性规划求解器获得的目标函数的解，用于进一步处理。从标准单元库中选择栅极配置，以根据目标函数的求解来优化要调整大小的逻辑门的行为。

58. 发明授权

US08612911B2 Estimating power consumption of an electronic circuit 有权
标题翻译：估计电子电路的功耗
公开(公告)号：US08612911B2
公开(公告)日：2013-12-17
申请号：US13365961
申请日：2012-02-03
申请人： Thomas Buechner , Markus Buehler , Philipp Panitz , Lei Wang , Markus Olbrich
发明人： Thomas Buechner , Markus Buehler , Philipp Panitz , Lei Wang , Markus Olbrich
IPC分类号： G06F9/455 , G06F17/50
CPC分类号： G06F17/5022 , G06F2217/78 , G06F2217/84
摘要： A method comprises estimating power consumption of an electronic circuit. The estimating includes assigning a first gate of the at least one gate into a priority queue based on a levelized result of the electronic circuit for a full circuit calculation and assigning a second gate of the at least one gate into the priority queue which fan-out gate is directly connected to a fan-in gate of a resized gate for an incremental circuit calculation. The estimating includes, for each gate from the priority queue, performing the following operations. Latest and earliest signal arrival times at an output net of the gate are determined by static timing analysis and calculating a glitch window as difference, and a transition metric is calculated for the output net based on the glitch window. The operations include determining an upper bound of signal transitions, and estimating the power consumption based on the upper bound.
摘要翻译：一种方法包括估计电子电路的功耗。估计包括基于用于全电路计算的电子电路的等级化结果将至少一个门的第一门分配到优先级队列中，并且将至少一个门的第二门分配到优先队列中，该优先队列中的扇出栅极直接连接到调整大小的门的扇入栅极用于增量电路计算。对于来自优先级队列的每个门，该估计包括执行以下操作。通过静态时序分析和将毛刺窗口计算为差异来确定门的输出网络处的最新和最早的信号到达时间，并且基于毛刺窗口为输出网络计算转移度量。这些操作包括确定信号转换的上限，以及基于上限来估计功耗。

59. 发明授权

US08607439B1 Method for providing an energy assisted magnetic recording (EAMR) head 有权
标题翻译：提供能量辅助磁记录（EAMR）头的方法
公开(公告)号：US08607439B1
公开(公告)日：2013-12-17
申请号：US12751883
申请日：2010-03-31
申请人： Lei Wang , Dujiang Wan
发明人： Lei Wang , Dujiang Wan
IPC分类号： G11B5/127 , H01R31/00
CPC分类号： G11B5/105 , G11B5/102 , G11B2005/0021
摘要： A method and system for providing an energy assisted magnetic recording (EAMR) head are described. The method and system include providing a slider, an EAMR transducer coupled with the slider, and a top layer on the slider. The top layer includes a mirror well therein and has a substantially flat top surface. The method and system further includes providing a laser including a light-emitting surface and providing a mirror optically coupled with the laser. The laser is coupled to the top surface of the top layer external to the mirror well. The mirror has a bottom surface and a reflective surface facing the light-emitting surface of the laser. A portion of the bottom surface of the mirror is affixed to the top surface of the top layer. A portion of the mirror resides in the mirror well.
摘要翻译：描述了一种用于提供能量辅助磁记录（EAMR）头的方法和系统。该方法和系统包括提供滑块，与滑动器耦合的EAMR换能器和滑块上的顶层。顶层在其中包括镜孔，并具有基本平坦的顶表面。该方法和系统还包括提供包括发光表面的激光器并提供与激光器光学耦合的反射镜。激光器耦合到镜子外部的顶层的顶表面。反射镜具有面向激光器的发光表面的底表面和反射表面。镜子底面的一部分固定在顶层的顶面。镜子的一部分位于镜子井中。

60. 发明授权

US08593914B2 Method and system for optically coupling a laser with a transducer in an energy assisted magnetic recording disk drive 有权
标题翻译：用于在能量辅助磁记录磁盘驱动器中将激光与换能器光学耦合的方法和系统
公开(公告)号：US08593914B2
公开(公告)日：2013-11-26
申请号：US12976770
申请日：2010-12-22
申请人： Lei Wang , Shing Lee , Sergei Sochava , Hyojune Lee , Arkadi B. Goulakov
发明人： Lei Wang , Shing Lee , Sergei Sochava , Hyojune Lee , Arkadi B. Goulakov
IPC分类号： G11B11/00
CPC分类号： G11B5/6088 , G11B5/105 , G11B5/3166 , G11B2005/0021
摘要： A method and system for providing an energy assisted magnetic recording (EAMR) head are described. The EAMR head includes a laser, a slider, and an EAMR transducer. The laser has a main emitter and at least one alignment emitter. The slider includes at least one alignment waveguide, at least one output device, and an air-bearing surface (ABS). The alignment waveguide(s) are aligned with the alignment emitter(s). The EAMR transducer is coupled with the slider and includes a waveguide aligned with main emitter. The waveguide is for directing energy from the main emitter toward the ABS.
摘要翻译：描述了一种用于提供能量辅助磁记录（EAMR）头的方法和系统。 EAMR头包括激光，滑块和EAMR传感器。激光器具有主发射极和至少一个对准发射极。滑块包括至少一个对准波导，至少一个输出装置和空气轴承表面（ABS）。对准波导与对准发射器对准。 EAMR传感器与滑块耦合并且包括与主发射器对准的波导。波导用于将能量从主发射器引向ABS。

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