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51. 发明授权

US08173170B2 Drug carrier and drug carrier kit for inhibiting fibrosis 有权
标题翻译：用于抑制纤维化的药物载体和药物载体试剂盒
公开(公告)号：US08173170B2
公开(公告)日：2012-05-08
申请号：US11793736
申请日：2005-12-22
申请人： Yoshiro Niitsu , Junji Kato , Yasushi Sato
发明人： Yoshiro Niitsu , Junji Kato , Yasushi Sato
IPC分类号： A61K9/127 , A61K9/14 , A61K31/07 , C12N15/11
CPC分类号： A61K31/07 , A61K9/0019 , A61K9/127 , A61K9/14 , A61K31/7088 , A61K38/1833 , A61K38/1841 , A61K38/1858 , A61K45/06 , A61K47/6911 , Y10S514/893 , Y10T428/2982 , A61K2300/00
摘要： An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier to a retinoid derivative such as vitamin A or a vitamin A analog or encapsulating the same in the drug carrier, a drug for therapeutic use can be delivered specifically to astrocytes. As a result, an astrocyte-related disease can be efficiently and effectively inhibited or prevented while minimizing side effects. As the drug inhibiting the activity or growth of astrocytes, for example, a siRNA against HSP47 which is a collagen-specific molecule chaperone may be encapsulated in the drug carrier. Thus, the secretion of type I to type IV collagens can be inhibited at the same time and, in its turn, fibrosis can be effectively inhibited.
摘要翻译：含有类视黄醇衍生物和/或维生素A类似物作为成分的星形胶质细胞特异性药物载体; 一种使用该药物的药物递送方法; 含有该药物的药物; 以及使用该药物的治疗方法。通过将药物载体与维生素A或维生素A类似物的类视黄醇衍生物结合或将其包封在药物载体中，用于治疗用途的药物可以特异性递送至星形胶质细胞。结果，可以有效地有效地抑制或预防星形胶质细胞相关疾病，同时尽量减少副作用。作为抑制星形胶质细胞活性或生长的药物，例如可以将作为胶原特异性分子伴侣的HSP47的siRNA包封在药物载体中。因此，可以同时抑制I型至IV型胶原的分泌，从而可以有效地抑制纤维化。

52. 发明授权

US08012231B2 Particulate matter analyzer, collecting filter and system for analyzing and collecting samples from fluids 有权
标题翻译：颗粒物质分析仪，收集过滤器和用于分析和收集流体样品的系统
公开(公告)号：US08012231B2
公开(公告)日：2011-09-06
申请号：US11768818
申请日：2007-06-26
申请人： Katsumi Saitoh , Junji Kato , Masahiko Fujiwara , Masayoshi Shinohara
发明人： Katsumi Saitoh , Junji Kato , Masahiko Fujiwara , Masayoshi Shinohara
IPC分类号： B01D59/50
CPC分类号： B01D46/0002 , B01D46/0006 , B01D46/10 , G01N1/2202 , G01N1/2205 , G01N15/0625 , Y10S55/03
摘要： A particulate collection system, including a particulate matter analyzer and collecting filter, provides a method of analyzing and collecting samples from fluids, such as collecting particulate matter from air. A mass measuring unit and composition analyzing unit can be provided for either simultaneous or immediately consecutive measurements within a single instrument. The filter material can have an antistatic electricity characteristic and can be impregnated with reference material to enable calibration of the composition analyzing unit.
摘要翻译：包括颗粒物质分析器和收集过滤器的颗粒收集系统提供了一种从流体中分析和收集样品的方法，例如从空气中收集颗粒物质。可以提供质量测量单元和组成分析单元用于在单个仪器内的同时或立即连续的测量。过滤材料可以具有抗静电电特性，并且可以用参考材料浸渍以使组合物分析单元能够校准。

53. 发明申请

US20080188002A1 METHOD AND APPARATUS FOR REMOVING SELENIUM OXIDE IN A SAMPLE, AND METHOD AND APPARATUS FOR MEASURING MERCURY IN COAL COMBUSTION EXHAUST GAS BY USING THE SAME 审中-公开
标题翻译：用于在样品中除去氧化铅的方法和装置，以及用于测量煤燃烧中的汞的方法和装置使用它们的排气
公开(公告)号：US20080188002A1
公开(公告)日：2008-08-07
申请号：US12024839
申请日：2008-02-01
申请人： Junji Kato , Shigeyuki Akiyama , Fujio Koga , Koji Ishikawa
发明人： Junji Kato , Shigeyuki Akiyama , Fujio Koga , Koji Ishikawa
IPC分类号： G01N31/12 , G01N33/20 , B01D3/00
CPC分类号： G01N33/0045 , B01D53/1456 , B01D53/77 , B01D2251/408 , B01D2251/604 , B01D2255/202 , B01D2255/50 , B01D2257/60
摘要： There is provided a method and apparatus for removing selenium oxide in a sample as well as a method and apparatus for measuring mercury in coal combustion exhaust gas by using the same. The apparatus for removing selenium oxide in a sample, comprising: (1) a heating introduction path for heating a sample, (2) a primary cooling unit having a flow path through which the heated sample flows countercurrently to cooling water, whereby the heated sample is mixed with, and cooled by, cooling water, (3) a secondary cooling unit having a spiral flow path for cooling the mixed gas and having a space for gas/liquid separation at the end of the spiral flow path, (4) a regenerator for introducing condensed water from the secondary cooling unit, and (5) a condensed water-cooling path for connecting the regenerator to the primary cooling unit.
摘要翻译：提供了一种用于除去样品中的氧化硒的方法和装置，以及通过使用该方法和装置测量煤燃烧废气中的汞。用于除去样品中的氧化硒的装置，包括：（1）用于加热样品的加热引入路径，（2）具有流动路径的主冷却单元，所述加热样品通过该流路与冷却水逆流流动，由此加热样品（3）二次冷却单元，其具有用于冷却混合气体的螺旋流动路径，并且在螺旋流动路径的端部具有用于气/液分离的空间，（4）a 用于从二次冷却单元引入冷凝水的再生器，以及（5）将再生器连接到一次冷却单元的冷凝水冷路。

54. 发明授权

US07409480B2 Electronic equipment, method of receiving data, method of transmitting data, method of setting channel and method of grouping electronic equipment into channels 失效
标题翻译：电子设备，数据接收方法，数据传输方法，信道设置方法以及电子设备分组通道的方法
公开(公告)号：US07409480B2
公开(公告)日：2008-08-05
申请号：US10303337
申请日：2002-11-25
申请人： Hajime Hata , Junji Kato , Makoto Sato
发明人： Hajime Hata , Junji Kato , Makoto Sato
IPC分类号： H04L12/28 , H04J3/16 , H04J3/02 , G06F3/00 , G06F13/36
CPC分类号： H04L12/40065 , H04L12/64 , H04N5/4401 , H04N5/775 , H04N5/782 , H04N9/8042 , H04N21/43632
摘要： It becomes possible for a user to set a transmission or reception channel arbitrarily and easily. Each of equipment connected to an IEEE 1394 bus may include a register provided within a RAM 113 to thereby set a transmission or reception default channel. If channels used in the transmission and the reception are not set when the transmission is started, then default channel may be used. When equipment is set to a channel setting mode by operating an operation section 116, a control section 112 may display a channel setting picture on a display section 115. In this state, a user may select a set channel by operating an up-key 116a and a down-key 116b of the operation section 116. Thereafter, when a user operates a “YES” key 116c, the control section 112 may write a selected channel in the above-mentioned register, and ends a default channel setting operation. A user can set the transmission or reception channel arbitrarily and easily.
摘要翻译：用户可以任意且容易地设置发送或接收信道。连接到IEEE 1394总线的每个设备可以包括设置在RAM 113内的寄存器，从而设置发送或接收默认信道。如果发送和接收中使用的信道在发送开始时未设置，则可以使用默认信道。当通过操作操作部分116将设备设置为通道设置模式时，控制部分112可以在显示部分115上显示频道设置画面。在这种状态下，用户可以通过操作操作部分116的上键116a和下键116b来选择设定的频道。此后，当用户操作“是”键116c时，控制部分112可以将所选择的频道写入上述寄存器中，并且结束默认频道设置操作。用户可以任意且容易地设置发送或接收通道。

55. 发明申请

US20070181293A1 Heat exchanger and producing method thereof 审中-公开
标题翻译：热交换器及其制造方法
公开(公告)号：US20070181293A1
公开(公告)日：2007-08-09
申请号：US11700569
申请日：2007-01-31
申请人： Junji Kato , Naoki Sugimoto
发明人： Junji Kato , Naoki Sugimoto
IPC分类号： F28F9/02
CPC分类号： F28F9/0246 , F28D1/05366 , F28F9/0224
摘要： A heat exchanger and a production method thereof are disclosed. A through hole (17) is formed in a second header member (17) of a first refrigerant header tank (14) of segmentation type. A protrusion (20a) of a first connector (20) for pipe connection is deformed by being inserted into the through hole (17b) and thus tacked by engagement. Under this condition, the first header member (16) is fitted and tacked on the second header member (17) so that the first connector (20), the second head member (17) and the first head member (16) are integrally brazed and coupled. By doing so, the first connector (20) can be properly coupled to the first refrigerant header tank (14). Further, the first connector (20) can be tacked by engagement before the first refrigerant header tank (14) assumes a cylindrical shape, and therefore the workability of tacking the first connector (20) is improved.
摘要翻译：公开了一种热交换器及其制造方法。在分割型的第一制冷剂集水箱（14）的第二集管部件（17）中形成有通孔（17）。用于管连接的第一连接器（20）的突起（20a）通过插入通孔（17b）而变形，并因此通过接合而固定。在这种状态下，第一集管部件（16）装配并固定在第二集管部件（17）上，使得第一连接器（20），第二磁头部件（17）和第一磁头部件（16）整体钎焊并耦合。通过这样做，第一连接器（20）可以适当地联接到第一制冷剂集水箱（14）。此外，第一连接器（20）可以在第一制冷剂集水箱（14）呈圆柱形状之前通过接合而固定，因此提高了固定第一连接器（20）的可操作性。

56. 发明申请

US20070137839A1 Heat exchanger 有权
标题翻译：热交换器
公开(公告)号：US20070137839A1
公开(公告)日：2007-06-21
申请号：US11641420
申请日：2006-12-19
申请人： Koichi Yamamoto , Ryouichi Sanada , Junji Kato
发明人： Koichi Yamamoto , Ryouichi Sanada , Junji Kato
IPC分类号： F28D7/10
CPC分类号： F28D1/05375 , F28D1/0443 , F28D2021/0084 , F28D2021/0089 , F28F9/001 , F28F9/0246 , F28F2009/0287
摘要： A heat exchanger 51 comprises: left and right header tanks 53 and 55 disposed in parallel; top and bottom side plates 57 and 59 that couple respectively both ends of the pair of the header tanks 53 and 55; a first tubes 61 comprised of a plurality of tubes connected between the pair of the header tanks 53 and 55 at both ends that is disposed in a region somewhat nearer the bottom side plate 59 as a condenser; and a second tubes that is disposed in a region somewhat nearer the top side plate 57 as an oil cooler, wherein each tube in the second tubes 99 has a cross-sectional shape identical to that of each tube in the first tubes 61 and the top side plate 57 is formed to have a squared U-shaped cross section so that a return pipe 101 communicating with the second tubes 99 can .re disposed along a groove having the squared U-shaped cross section of the top side plate 57. Therefore, this heat exchanger can be manufactured easily with low cost and it can prevent the return pipe from being crushed.
摘要翻译：热交换器51包括：平行设置的左右集水箱53和55; 顶部和底部侧板57和59分别与一对集水箱53和55的两端相连; 第一管61由连接在一对集水箱53和55之间的多个管组成，两个管两端设置在靠近底侧板59的区域中作为冷凝器; 以及设置在比较靠近顶侧板57的区域作为油冷却器的第二管，其中第二管99中的每个管具有与第一管61和顶部中的每个管的截面形状相同的横截面形状侧板57形成为具有平面的U形横截面，使得与第二管99连通的返回管101可以沿着顶侧板57的U形横截面的凹槽设置。因此，能够以低成本容易地制造该热交换器，能够防止回流管被破碎。

57. 发明申请

US20050084959A1 Immortalized mesenchymal cells and utilization thereof 审中-公开
标题翻译：永生化间充质细胞及其利用
公开(公告)号：US20050084959A1
公开(公告)日：2005-04-21
申请号：US10493868
申请日：2002-10-31
申请人： Hirofumi Hamada , Yutaka Kawano , Kiminori Nakamura , Masayoshi Kobune , Osamu Honmou , Atsushi Tanooka , Shin-ichi Oka , Katsunori Sasaki , Hajime Tsuda , Yoshinori Ito , Junji Kato , Takuya Matsunaga , Yoshiro Niitsu
发明人： Hirofumi Hamada , Yutaka Kawano , Kiminori Nakamura , Masayoshi Kobune , Osamu Honmou , Atsushi Tanooka , Shin-ichi Oka , Katsunori Sasaki , Hajime Tsuda , Yoshinori Ito , Junji Kato , Takuya Matsunaga , Yoshiro Niitsu
IPC分类号： A61K35/12 , A61K35/18 , A61K35/28 , A61K35/32 , C12N5/0775 , C12N5/078 , C12N5/08
CPC分类号： C12N5/0618 , A61K35/18 , A61K35/28 , A61K35/32 , A61K2035/124 , C12N5/0641 , C12N5/0663 , C12N2503/02 , C12N2506/1353 , C12N2510/04
摘要： The method developed herein is for expanding cord blood-derived hematopoietic stem cells to a degree that is sufficiently safe for clinical application, such as the transplantation of hematopoietic stem cells into adult patients. Further, to prepare a number of mesenchymal stem cells or mesenchymal cells that have conventionally been available only in an extremely small number, an immortalizing gene such as that of telomerase is introduced alone into mesenchymal stem cells, mesenchymal cells or the like, so as to induce the differentiation of the expanded mesenchymal stem cells.
摘要翻译：本文开发的方法是将脐带血衍生的造血干细胞扩增至对临床应用足够安全的程度，例如将造血干细胞移植到成年患者中。此外，为了制备通常仅以极小数目可获得的许多间充质干细胞或间充质细胞，将端粒酶等永生化基因单独导入间充质干细胞，间充质细胞等，以诱导扩大的间充质干细胞的分化。

58. 发明授权

US06556464B2 PWM converter system 失效
标题翻译： PWM转换器系统
公开(公告)号：US06556464B2
公开(公告)日：2003-04-29
申请号：US09956257
申请日：2001-09-20
申请人： Keijirou Sakai , Toshiaki Okuyama , Kinya Nakatsu , Seiji Ishida , Hiroshi Fujii , Junji Kato , Masahiro Hiraga
发明人： Keijirou Sakai , Toshiaki Okuyama , Kinya Nakatsu , Seiji Ishida , Hiroshi Fujii , Junji Kato , Masahiro Hiraga
IPC分类号： H02M75387
CPC分类号： H02M1/4233 , H02M1/4216 , H02M2001/0012 , Y02B70/126
摘要： A single-phase PWM converter system in accordance with the present invention employs a sample-and-hold circuit which samples and holds a direct current in the state wherein one of two-phase gate signals of a positive or negative side arm is ON and the other phase is OFF, determines the sign of an output of the sample-and-hold circuit according to the two-phase gate condition, detects a phase current at the input side of the converter, and controls a voltage at the input side of the converter so that the detected current value agrees with a power supply current command. Further, a three-phase PWM converter system in accordance with the present invention detects the effective current and the ineffective current of the power supply current from the direct current, and based on the values, controls the PWM converter so that the sine wave power supply current whose power supply power factor is 1 is provided.
摘要翻译：根据本发明的单相PWM转换器系统采用采样和保持电路，其采样和保持直流电流，其中正或负侧臂的两相门信号之一为ON，其他相位为OFF，根据两相门条件确定采样保持电路的输出的符号，检测转换器输入侧的相电流，并控制转换器的输入侧的电压转换器，使得检测到的电流值与电源电流指令一致。此外，根据本发明的三相PWM转换器系统从直流电流检测电源电流的有效电流和无效电流，并且基于在该值上，控制PWM转换器，使得提供功率因数为1的正弦波电源电流。

59. 发明授权

US06105058A Communication control method and apparatus 失效
标题翻译：通信控制方法和装置
公开(公告)号：US06105058A
公开(公告)日：2000-08-15
申请号：US27005
申请日：1998-02-20
申请人： Junji Kato , Susumu Nagano
发明人： Junji Kato , Susumu Nagano
IPC分类号： G11B31/00 , H04L12/28 , H04L12/40 , H04L29/08 , G06F3/14 , G06F13/14
CPC分类号： H04L12/413 , H04L12/2803 , H04L12/2816 , H04L12/2823 , H04L12/40143 , H04L2012/2849
摘要： A plurality of terminals are connected to a common data bus. Each terminal is capable of issuing and processing two types of commands: a simultaneous command and a non-simultaneous command. A receiving terminal processes every simultaneous command, but processes only the most recently received non-simultaneous command. The receiving terminal acknowledges the receipt of every received simultaneous command and of every executed non-simultaneous command. The receiving terminal sends a reject signal for every received non-simultaneous signal that was not executed.
摘要翻译：多个终端连接到公共数据总线。每个终端能够发出和处理两种类型的命令：同时命令和非同时命令。接收终端处理每个同时的命令，但仅处理最近接收的非同时命令。接收终端确认接收到每个接收到的同时命令和每个执行的非同时命令。接收终端对于未执行的每个接收的非同时信号发送拒绝信号。

60. 发明授权

US5919261A Methods and apparatus for controlling operation of a link layer controller based upon a state of connection between multiple electronic apparatus 失效
标题翻译：基于多个电子设备之间的连接状态来控制链路层控制器的操作的方法和装置
公开(公告)号：US5919261A
公开(公告)日：1999-07-06
申请号：US910854
申请日：1997-08-13
申请人： Yukihiko Aoki , Junji Kato
发明人： Yukihiko Aoki , Junji Kato
IPC分类号： H04L12/28 , G06F1/32 , H04L12/40 , H04L12/64 , G06F13/00 , G06F1/26
CPC分类号： H04L12/40078 , G06F1/32 , G06F1/3253 , Y02B60/1235
摘要： The invention provides an electronic apparatus and an operation mode controlling method for the same by which the power dissipation of a communication interface of a node on an IEEE 1394 serial bus is reduced. The electronic apparatus includes a communication interface which is composed of a physical layer controller, a link layer controller and a CPU. When the electronic apparatus is not connected to any other electronic apparatus via an IEEE 1394 serial bus, the link layer controller does not operate, but after the connection is established, the link layer controller operates.
摘要翻译：本发明提供了一种电子装置及其操作模式控制方法，通过该方法控制IEEE 1394串行总线上的节点的通信接口的功率消耗。电子设备包括由物理层控制器，链路层控制器和CPU组成的通信接口。当电子设备未通过IEEE 1394串行总线连接到任何其他电子设备时，链路层控制器不工作，但是在连接建立之后，链路层控制器操作。

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