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51. 发明申请

US20060122624A1 Bone treatment systems and methods 有权
公开(公告)号：US20060122624A1
公开(公告)日：2006-06-08
申请号：US11196045
申请日：2005-08-02
申请人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson
发明人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson
IPC分类号： A61F2/34
CPC分类号： A61B17/7095 , A61B17/7098 , A61B17/864 , A61B17/8811 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.

52. 发明申请

US20060122622A1 Bone treatment systems and methods 有权
公开(公告)号：US20060122622A1
公开(公告)日：2006-06-08
申请号：US11165651
申请日：2005-06-24
申请人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson , C. Rappleye
发明人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson , C. Rappleye
IPC分类号： A61F2/34
CPC分类号： A61B17/8836 , A61B17/7095 , A61B17/7098 , A61B17/864 , A61B17/8811 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.

53. 发明申请

US20060122614A1 Bone treatment systems and methods 审中-公开
公开(公告)号：US20060122614A1
公开(公告)日：2006-06-08
申请号：US11196089
申请日：2005-08-02
申请人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson
发明人： Csaba Truckai , John Shadduck , Robert Luzzi , Grace Carlson
IPC分类号： A61B17/58
CPC分类号： A61B17/7095 , A61B17/7098 , A61B17/864 , A61B17/8811 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.

54. 发明申请

US20060085009A1 Implants and methods for treating bone 审中-公开
标题翻译：植入物和治疗骨的方法
公开(公告)号：US20060085009A1
公开(公告)日：2006-04-20
申请号：US11199582
申请日：2005-08-08
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/34
CPC分类号： A61L27/56 , A61B17/70 , A61B17/7094 , A61F2/08 , A61F2/30771 , A61F2/30965 , A61F2/442 , A61F2002/30014 , A61F2002/30069 , A61F2002/30909 , A61F2002/4495 , A61F2250/0018 , A61L27/04 , A61L27/14 , A61L2430/38
摘要： This invention relates to biomedical implants for filling, supporting or treating bone. In one embodiment, the implant comprises an electrospun polymer scaffold that is thereafter plated with a metal to provide a selected high modulus. Such an implant can be fabricated with a selected porosity for tissue ingrowth. The implant can be further provided with a varied modulus along the length of the implant body for inducing bending of the implant for packing in a bone. In another embodiment, the implant is fabricated in an elongated configuration for introducing into bone to treat a vertebral fracture. In another embodiment, the implant can be configured with helical threads for helically driving the implant into a bone.
摘要翻译：本发明涉及用于填充，支撑或治疗骨的生物医学植入物。在一个实施方案中，植入物包括电纺聚合物支架，然后电镀金属以提供选定的高模量。这种植入物可以用组织向内生长的选择的孔隙来制造。植入物可以进一步沿着植入体的长度设置变化的模量，用于诱导植入物弯曲以包装在骨中。在另一个实施例中，植入物被制造成细长结构，用于引入骨中以治疗椎骨骨折。在另一个实施例中，植入物可被构造成螺旋螺纹，用于将植入物螺旋地驱动到骨中。

55. 发明申请

US20060058782A1 Electrical discharge devices and techniques for medical procedures 有权
公开(公告)号：US20060058782A1
公开(公告)日：2006-03-16
申请号：US11065180
申请日：2005-02-23
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/18 , A61B19/00
CPC分类号： A61B17/22004 , A61B18/042 , A61B2017/22008 , A61B2018/1213
摘要： A medical instrument coupled to first and second energy means and a computer controller for the controlled volumetric removal of thin tissue layers. The system provides a source for introducing a gas to controllably form and capture transient gas volumes in a microchannel structure at the working surface of the instrument that interfaces with a targeted tissue site. Each of the microchannel features of the working surface carries an electrode element coupled to the electrical source. The energy may be applied to the targeted site in either of two modes of operation, depending in part on voltage and repetition rate of energy delivery. In one mode of energy application, electrical potential is selected to cause an intense electrical arc across the transient ionized gas volumes to cause an energy-tissue interaction characterized by tissue vaporization. In another preferred mode of energy delivery, the system applies selected levels of energy to the targeted site by means of an energetic plasma at the instrument working surface to cause molecular volatilization of surface macromolecules thus resulting in material removal. Both modes of operation limit collateral thermal damage to tissue volumes adjacent to the targeted site. Another preferred embodiment provides and an ultrasound source or other vibrational source coupled to the working end to cause cavitation in fluid about the working end.

56. 发明申请

US20050267570A1 Endovascular occlusion devices and methods of use 审中-公开
标题翻译：血管内闭塞装置及使用方法
公开(公告)号：US20050267570A1
公开(公告)日：2005-12-01
申请号：US11140421
申请日：2005-05-27
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61B17/00 , A61B17/12 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/90
CPC分类号： A61F2/90 , A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12172 , A61B2017/00867 , A61F2/07 , A61F2/856 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/077 , A61F2002/30092 , A61F2002/823 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2210/0014 , A61F2210/0076
摘要： An implantable stent-like device for treating and occluding arteriovascular malformations (AVMs), fistulas, varicose veins or the like. More particularly, this invention relates to an implant body that includes an open-cell shape-transformable polymer structure that provides stress-free means for occluding an AVM without applying additional pressures an any distended walls of the AVM. In one embodiment, the shape-transformable polymer is a shape memory polymer implant body that self-deploys from a temporary shape to a memory shape. In another embodiment, the shape memory polymer structure is capable of a temporary compacted shape for carrying about the struts of an expandable stent for self-deployment to occlude an aneurysm.
摘要翻译：用于治疗和阻塞动脉血管畸形（AVM），瘘，静脉曲张等的可植入支架样装置。更具体地说，本发明涉及一种植入体，其包括开放细胞形状可变形的聚合物结构，其提供用于阻塞AVM的无压力装置，而不对AVM的任何扩张壁施加附加压力。在一个实施方案中，形状可变形聚合物是形状记忆聚合物植入体，其自身从临时形状展现到记忆形状。在另一个实施方案中，形状记忆聚合物结构能够临时压实形状，用于承载用于自展开以阻塞动脉瘤的可扩张支架的支柱。

57. 发明申请

US20050171535A1 Electrosurgical instrument and method of use 有权
标题翻译：电外科仪器及使用方法
公开(公告)号：US20050171535A1
公开(公告)日：2005-08-04
申请号：US10993413
申请日：2004-11-18
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B18/1445 , A61B2018/00077 , A61B2018/00083 , A61B2018/00125 , A61B2018/00148 , A61B2018/0016 , A61B2018/00404 , A61B2018/00601 , A61B2018/0063 , A61B2018/1412 , A61B2018/1455
摘要： Embodiments of the invention provide an electrosurgical jaw structure comprising first and second opposing jaws one or both of which include 3D variable resistance bodies. The jaw structure can be part of the working end of a surgical instrument. In one embodiment, the jaws can comprise first and second energy-delivery jaw surfaces having first and second 3D variable resistance bodies, with the jaw surface configured to be coupled to an Rf source. The 3D variable resistance bodies can define different temperature-resistance curves. The 3D bodies can be configured to control ohmic heating of tissue by modulating the delivery of Rf energy to tissue. Jaw structures having the 3D bodies can be used to engage and produce high strength tissue welds in targeted tissue including tissue volumes having varying tissue types. Such jaw structures can be configured to simultaneously apply different energy levels to each tissue type within the tissue volume.
摘要翻译：本发明的实施例提供一种电外科钳口结构，其包括第一和第二相对的钳口，其中一个或两个包括3D可变电阻体。钳口结构可以是外科器械的工作端的一部分。在一个实施例中，夹爪可以包括具有第一和第二3D可变电阻体的第一和第二能量输送钳口表面，其中钳口表面被配置为耦合到Rf源。 3D可变电阻体可以定义不同的耐温曲线。 3D体可以被配置成通过调节Rf能量递送到组织来控制组织的欧姆加热。可以使用具有3D体的颚结构来接合和产生包括具有不同组织类型的组织体积的靶组织中的高强度组织焊接。这种钳口结构可以被配置为同时对组织体积内的每种组织类型施加不同的能量水平。

58. 发明申请

US20050149183A1 Intraocular lens system and method for power adjustment 有权
标题翻译：人工晶状体系统及功率调节方法
公开(公告)号：US20050149183A1
公开(公告)日：2005-07-07
申请号：US11069136
申请日：2005-02-28
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/1613 , A61F2002/169 , A61F2250/0001
摘要： An intraocular lens (IOL) that provides for optical power adjustment following its implantation, for example, for use in treating cataract patients. The lens body has first and second surface portions that bound at least one interior chamber or space that extends from the central optic portion to the lens periphery. The interior chamber or space has a microporous body that is intermediate inner and outer portions of the space. In one embodiment, the microporous body is capable of cooperating with an external Rf or light source to expose a charge to a charge-carrying fluid within the interior chamber. By this system, fluid flows are induced to alter the optical parameters of the lens.
摘要翻译：眼内透镜（IOL），其在植入之后提供光学功率调整，例如用于治疗白内障患者。透镜体具有第一和第二表面部分，其结合从中心光学部分延伸到透镜周边的至少一个内部室或空间。内部室或空间具有位于该空间的中部内部和外部的微孔体。在一个实施例中，微孔体能够与外部Rf或光源配合，以将电荷暴露于内部室内的带电荷的流体。通过该系统，引起流体流动以改变透镜的光学参数。

59. 发明授权

US08562620B2 Bone treatment systems 有权
标题翻译：骨治疗系统
公开(公告)号：US08562620B2
公开(公告)日：2013-10-22
申请号：US12427531
申请日：2009-04-21
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8805 , A61B17/7095 , A61B17/8822 , A61B17/8827
摘要： Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation.
摘要翻译：用于治疗脊椎压缩性骨折的系统，骨水泥和方法可以利用包含可混合液体单体组分和包括聚合物颗粒在内的非液体组分的骨粘固剂，其中非液体组分构造成用于通过液体单体控制暴露于液体单体骨水泥的设定间隔。在使用方法中，将液体和非液体组分混合，并将骨粘固剂注入到骨中，其中提供了延长的凝固间隔，其中混合物配置为防止不想要的外渗的流动性。

60. 发明申请

US20120271300A9 MEDICAL INSTRUMENT AND METHOD OF USE 有权
标题翻译：医用仪器及其使用方法
公开(公告)号：US20120271300A9
公开(公告)日：2012-10-25
申请号：US11329381
申请日：2006-01-10
申请人： John Shadduck , Michael Hoey
发明人： John Shadduck , Michael Hoey
IPC分类号： A61B18/18 , A61F7/12 , A61F7/00
CPC分类号： A61B18/042 , A61B18/04 , A61B2018/00619 , A61B2018/0063 , A61B2018/046 , A61B2018/048
摘要： An instrument for thermally-mediated therapies in targeted tissue volumes or for volumetric removal of tissue. In one embodiment, the instrument has an interior chamber that includes a diffuser structure for diffusing a biocompatible conductive fluid that is introduced under high pressure. The interior chamber further includes surfaces of opposing polarity electrodes for vaporizing the small cross-section diffused fluid flows created within a diffuser structure. In one embodiment, the diffuser structure includes a negative temperature coefficient of resistance material between the opposing polarity surfaces. The NTCR structure can self-adjust the lengths of current paths between the opposing polarities to insure complete vaporization of the volume of flow of conductive fluid. The non-ionized vapor phase media is ejected from a working surface of the instrument and a controlled vapor-to-liquid phase change in an interface with tissue applies thermal energy substantially equal to the heat of vaporization to ablate tissue. In another embodiment, the instrument provides voltage means for converting the non-ionized vapor phase media into an ionized media or plasma for applying energy to body structure.
摘要翻译：用于靶向组织体积或体积去除组织的热介导疗法的仪器。在一个实施例中，仪器具有内部腔室，其包括用于扩散在高压下引入的生物相容性导电流体的扩散器结构。内部腔室还包括相对极性电极的表面，用于蒸发在扩散器结构内产生的小横截面扩散的流体流。在一个实施例中，扩散器结构包括在相对的极性表面之间的电阻材料的负温度系数。 NTCR结构可以自我调节相对极性之间的电流通路的长度，以确保导电流体流量的完全蒸发。非离子化的气相介质从仪器的工作表面喷出，并且与组织的界面中受控的蒸气 - 液相变化施加基本上等于蒸发热消融组织的热能。在另一个实施例中，仪器提供电压装置，用于将非电离气相介质转换成离子化介质或等离子体，以将能量施加到体结构。

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