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51. 发明申请

US20110315817A1 SYSTEMS AND DEVICES FOR REMOTELY OPERATED UNMANNED AERIAL VEHICLE REPORT-SUPPRESSING LAUNCHER WITH PORTABLE RF TRANSPARENT LAUNCH TUBE 有权
标题翻译：用于远程操作的无人驾驶航空器报警系统和设备 - 带便携式射频透明发射管的超级发射器
公开(公告)号：US20110315817A1
公开(公告)日：2011-12-29
申请号：US13229377
申请日：2011-09-09
申请人： Carlos Thomas Miralles , Guan H. Su , Oleksandr Andryukov , John McNeil
发明人： Carlos Thomas Miralles , Guan H. Su , Oleksandr Andryukov , John McNeil
IPC分类号： B64F1/04
CPC分类号： B64F1/04 , B64C39/024 , B64C2201/08 , B64C2201/102 , B64C2201/146 , B64C2201/201 , B64F1/06 , F41A21/02 , F41F1/00 , F41F3/042 , F42B39/14
摘要： An unmanned aerial vehicle (UAV) launch tube that comprises a tethered sabot configured to engage a UAV within a launcher volume defined by an inner wall, the tethered sabot dimensioned to provide a pressure seal at the inner wall and tethered to the inner wall, and wherein the tethered sabot is hollow having an open end oriented toward a high pressure volume and a tether attached within a hollow of the sabot and attached to the inner wall retaining the high pressure volume or attach to the inner base wall. A system comprising a communication node and a launcher comprising an unmanned aerial vehicle (UAV) in a pre-launch state configured to receive and respond to command inputs from the communication node.
摘要翻译：一种无人驾驶飞行器（UAV）发射管，其包括被配置为将UAV接合在由内壁限定的发射器体积内的拴系的艉板，所述拴系的突出部的尺寸被设计成在内壁处提供压力密封并且系在内壁上，以及其中所述系留式破碎器是中空的，其具有朝向高压容积的开口端，并且连接在所述破坏物的中空部内并且附接到保持高压容积的内壁或附接到内底壁的内壁的系绳。一种包括通信节点和发射器的系统，其包括处于预发射状态的无人驾驶飞行器（UAV），其被配置为接收并响应来自所述通信节点的命令输入。

52. 发明申请

US20050239737A1 Identification of molecular interaction sites in RNA for novel drug discovery 审中-公开
标题翻译：鉴定用于新药发现的RNA中的分子相互作用位点
公开(公告)号：US20050239737A1
公开(公告)日：2005-10-27
申请号：US11146468
申请日：2005-06-07
申请人： David Ecker , Ranga Sampath , Richard Griffey , John McNeil
发明人： David Ecker , Ranga Sampath , Richard Griffey , John McNeil
IPC分类号： C12N15/09 , A61K31/7105 , A61K31/713 , A61K48/00 , A61P31/04 , C07H21/02 , C07H21/04 , C12N15/11 , C12Q1/68
CPC分类号： C12Q1/6876
摘要： Methods of identifying molecular interaction sites in eukaryotic and prokaryotic nucleic acids, especially RNA, are described. Secondary structural elements are identified from highly conserved sequences. Methods of preparing databases relating to such molecular interaction sites are also provided herein as are databases themselves. Therapeutic, agricultural, industrial, and other applicability results from interaction of such molecular interaction sites with “small” and other molecules.
摘要翻译：描述了在真核和原核核酸，特别是RNA中鉴定分子相互作用位点的方法。二级结构元件由高度保守的序列鉴定。本文还提供了与这种分子相互作用位点相关的数据库的制备方法，数据库本身也是如此。这种分子相互作用位点与“小”和其他分子的相互作用导致治疗，农业，工业和其他适用性。

53. 发明申请

US20050033524A1 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation 审中-公开
标题翻译：识别通过寡核苷酸调节的遗传靶标和产生用于基因调控的寡核苷酸
公开(公告)号：US20050033524A1
公开(公告)日：2005-02-10
申请号：US10649467
申请日：2003-08-27
申请人： Lex Cowsert , Brenda Baker , John McNeil , Susan Freier , Henri Sasmor , Douglas Brooks , Cara Ohashi , Jacqueline Wyatt , Alexander Borchers , Timothy Vickers
发明人： Lex Cowsert , Brenda Baker , John McNeil , Susan Freier , Henri Sasmor , Douglas Brooks , Cara Ohashi , Jacqueline Wyatt , Alexander Borchers , Timothy Vickers
IPC分类号： C12N15/09 , C07B61/00 , C12N15/10 , C12Q1/68 , C12Q1/6811 , C40B30/02 , C40B40/02 , C40B50/02 , C40B50/06 , G06F17/30 , G06F17/50 , G06F19/18 , G06F19/22 , G06F19/00 , G01N33/48 , G01N33/50 , C07H21/04
CPC分类号： C12Q1/6811 , B01J2219/007 , C12N15/1048 , G16B20/00 , G16B30/00 , G16B35/00 , G16C20/60
摘要： Interative, preferably computer based iterative processes for generating synthetic compounds with desired physical, chemical and/or bioactive properties, i.e., active compounds, are provided. During iterations of the processes, a target nucleic acid sequence is provided or selected, and a library of candidate nucleobase sequences is generated in silico according to defined criteria. A “virtual” oligonucleotide chemistry is chosen and a library of virtual oligonucleotide compounds having the selected nucleobase sequences is generated. These virtual compounds are reviewed and compounds predicted to have particular properties are selected. The selected compounds are robotically synthesized and are preferably robotically assayed for a desired physical, chemical or biological activity. Active compounds are thus generated and, at the same time, preferred sequences and regions of the target nucleic acid that are amenable to oligonucleotide or sequence-based modulation are identified.
摘要翻译：提供了用于产生具有期望的物理，化学和/或生物活性的合成化合物（即活性化合物）的相互优选的基于计算机的迭代方法。在该过程的迭代过程中，提供或选择靶核酸序列，并且根据确定的标准以计算机生成候选核碱基序列的文库。选择“虚拟”寡核苷酸化学，并产生具有选定的核碱基序列的虚拟寡核苷酸化合物文库。审查这些虚拟化合物，并选择预测具有特定性质的化合物。所选择的化合物是机械合成的，并且优选机械地测定所需的物理，化学或生物活性。因此产生活性化合物，并且同时确定适用于寡核苷酸或基于序列的调节的靶核酸的优选序列和区域。

54. 发明申请

US20110088395A1 COMBUSTION METHOD AND APPARATUS 有权
标题翻译：燃烧方法和装置
公开(公告)号：US20110088395A1
公开(公告)日：2011-04-21
申请号：US12736196
申请日：2009-03-19
申请人： John McNeil
发明人： John McNeil
IPC分类号： F02G3/00 , F02B43/00 , F02G5/00 , F01N5/02
CPC分类号： F02D41/0025 , C10L1/026 , F02B3/06 , F02D19/0647 , F02D19/0649 , F02D19/081 , F02M31/042 , F02M37/0064 , Y02E20/14 , Y02E50/13 , Y02T10/126 , Y02T10/16 , Y02T10/36 , Y02T50/678
摘要： A method of combusting a very low cetane number material comprises injecting said material into a combustion cylinder of a heterogeneous-charge compression-ignition engine and supplying to the cylinder inlet port supplying the chamber combustion air or working fluid at a temperature substantially above ambient for substantially the entire time that the engine is running. Other aspects of the invention provide a compression ignition engine for use in the method, and method of using the engine to combust fuels.
摘要翻译：燃烧非常低的十六烷值材料的方法包括将所述材料注入异质充电压缩点火发动机的燃烧气缸中，并将其供给到在大体上高于环境温度的温度下供应室燃烧空气或工作流体的气缸入口，整个发动机运行的时间。本发明的其它方面提供了一种用于该方法的压燃式发动机，以及使用该发动机燃烧燃料的方法。

55. 发明申请

US20070001462A1 Integrated renewable energy system 审中-公开
标题翻译：综合可再生能源系统
公开(公告)号：US20070001462A1
公开(公告)日：2007-01-04
申请号：US10553243
申请日：2004-04-08
申请人： John McNeil
发明人： John McNeil
IPC分类号： F01D15/10
CPC分类号： F02M25/12 , Y02E60/366 , Y02P20/133 , Y02T10/121 , Y02T10/16
摘要： A system and method are disclosed comprising coupling a compression ignition engine (17) to an AC electrical generator (18) and/or a DC hompolar generator (19), wherein the homopolar generator (19) produces an electric current which is used to electrolyse water into hydrogen and oxygen. The hydrogen from the water electrolysis process may be used as a renewable fuel, either in the form of a gaseous fuel or a reactant in a fuel cell. The oxygen from the water electrolysis unit (23) may be used to produce an oxygen enriched combustion atmosphere in the engine (17). The oxygen may optionally be used as a reactant, along with the hydrogen, in a fuel cell.
摘要翻译：公开了一种系统和方法，包括将压缩点火发动机（17）耦合到AC发电机（18）和/或DC均压发电机（19），其中所述单极发电机（19）产生用于电解的电流水进入氢气和氧气。来自水电解方法的氢气可以以燃料电池中的气体燃料或反应物的形式用作可再生燃料。来自水电解单元（23）的氧气可用于在发动机（17）中产生富氧燃烧气氛。氧气可以任选地与燃料电池中的氢一起用作反应物。

56. 发明授权

US4463245A Plasma cutting and welding torches with improved nozzle electrode cooling 失效
标题翻译：等离子切割和焊接焊枪具有改进的喷嘴电极冷却
公开(公告)号：US4463245A
公开(公告)日：1984-07-31
申请号：US391009
申请日：1982-06-23
申请人： John McNeil
发明人： John McNeil
IPC分类号： H05H1/28 , B23K9/00
CPC分类号： H05H1/28
摘要： A plasma torch (40) comprises a handle (41) having an upper end (41B) which houses the components forming a torch body (43). Body (33) incorporates a rod electrode (10) having an end which cooperates with an annular tip electrode (13) to form a spark gap. An ionizable fuel gas is fed to the spark gap via tube (44) within the handle (41), the gas from tube (44) flowing axially along rod electrode (10) and being diverted radially through apertures (16) so as to impinge upon and act as a coolant for a thin-walled portion (14) of the annular tip electrode (13). With this arrangement the heat generated by the electrical arc in the inter-electrode gap is substantially confined to the annular tip portion (13A) of electrode (13) which is both consumable and replaceable in that portion (13A) is secured by screw threads to the adjoining portion (13B) of electrode (13) and which is integral with the thin-walled portion (14).
摘要翻译：等离子体焰炬（40）包括具有容纳形成炬体（43）的部件的上端（41B）的手柄（41）。主体（33）包括具有与环形末端电极（13）配合以形成火花隙的端部的杆状电极（10）。通过管（41）内的管（44）将可电离的燃料气体供给到火花间隙，来自管（44）的气体沿着杆电极（10）轴向流动并且径向地转过孔（16），从而撞击并且用作环形尖端电极（13）的薄壁部分（14）的冷却剂。利用这种布置，电极间隙中的电弧产生的热量基本上限制在电极（13）的环形末端部分（13A）上，电极（13）的消耗和可更换部分（13A）通过螺纹固定到电极（13）的邻接部分（13B）并且与薄壁部分（14）成一体。

57. 发明授权

US4067567A Sheet roll assembly for copying machine 失效
标题翻译：复印机用纸卷组件
公开(公告)号：US4067567A
公开(公告)日：1978-01-10
申请号：US769895
申请日：1977-02-18
申请人： John McNeil
发明人： John McNeil
IPC分类号： B65H20/06 , B65H37/00 , G03B27/58 , B65H29/64
CPC分类号： B65H37/00 , B65H20/06 , G03B27/585 , Y10S242/03
摘要： A sheet roll assembly for a copying machine in which a sheet reproduction of a sheet original is printed and processed, the sheet reproduction and original being conveyed to the outside of the machine after printing and processing. The sheet roll assembly is attached to the exterior of the machine proximate to and below the level at which a sheet emerges from the machine. The sheet roll assembly comprises a belt conveyor having an upper surface moving in a direction opposite to the direction of displacement of the emerging sheet and adapted to engage the leading edge of the sheet, and a curved plate mounted on the end of the upper surface of the belt conveyor for catching the leading edge of the sheet and causing the sheet to be spirally rolled against the curved plate, the sheet being continuously driven against the curved plate by the translation motion of the belt conveyor.
摘要翻译：一种用于复印机的片材卷组件，其中印刷和处理片材原件的片材再现，片材再现和原件在印刷和加工之后被输送到机器的外部。片材卷组件附接到机器的外部，靠近和低于纸张从机器出来的水平面。片材卷组件包括带式输送机，该带式输送机具有在与出现的纸张的位移方向相反的方向上移动的上表面，并且适于接合纸张的前缘，以及安装在纸张的上表面的端部上的弯曲板用于抓住片材的前缘并使片材相对于弯曲板螺旋卷绕的带式输送机，片材通过带式输送机的平移运动被连续地驱动抵靠弯曲板。

58. 发明授权

US09187184B2 Systems and devices for remotely operated unmanned aerial vehicle report-suppressing launcher with portable rf transparent launch tube 有权
标题翻译：用于遥控无人机报警抑制发射器的系统和设备，配有便携式rf透明发射管
公开(公告)号：US09187184B2
公开(公告)日：2015-11-17
申请号：US13234044
申请日：2011-09-15
申请人： Carlos Thomas Miralles , Guan H. Su , Oleksandr Andryukov , John McNeil
发明人： Carlos Thomas Miralles , Guan H. Su , Oleksandr Andryukov , John McNeil
IPC分类号： B64F1/06 , B64C39/02 , F41A21/02 , F41F3/042 , F42B39/14
CPC分类号： B64F1/04 , B64C39/024 , B64C2201/08 , B64C2201/102 , B64C2201/146 , B64C2201/201 , B64F1/06 , F41A21/02 , F41F1/00 , F41F3/042 , F42B39/14
摘要： An unmanned aerial vehicle (UAV) launch tube that comprises a tethered sabot configured to engage a UAV within a launcher volume defined by an inner wall, the tethered sabot dimensioned to provide a pressure seal at the inner wall and tethered to the inner wall, and wherein the tethered sabot is hollow having an open end oriented toward a high pressure volume and a tether attached within a hollow of the sabot and attached to the inner wall retaining the high pressure volume or attach to the inner base wall. A system comprising a communication node and a launcher comprising an unmanned aerial vehicle (UAV) in a pre-launch state configured to receive and respond to command inputs from the communication node.
摘要翻译：一种无人驾驶飞行器（UAV）发射管，其包括被配置为将UAV接合在由内壁限定的发射器体积内的拴系的艉板，所述拴系的突出部的尺寸被设计成在内壁处提供压力密封并且系在内壁上，以及其中所述系留式破碎器是中空的，其具有朝向高压容积的开口端，并且连接在所述破坏物的中空部内并且附接到保持高压容积的内壁或附接到内底壁的内壁的系绳。一种包括通信节点和发射器的系统，其包括处于预发射状态的无人驾驶飞行器（UAV），其被配置为接收并响应来自所述通信节点的命令输入。

59. 发明授权

US08875685B2 Combustion method and apparatus 有权
标题翻译：燃烧方法和装置
公开(公告)号：US08875685B2
公开(公告)日：2014-11-04
申请号：US12736196
申请日：2009-03-19
申请人： John McNeil
发明人： John McNeil
IPC分类号： F02M31/04 , F02D19/06 , C10L1/02 , F02D19/08 , F02D41/00 , F02B3/06 , F02M37/00
CPC分类号： F02D41/0025 , C10L1/026 , F02B3/06 , F02D19/0647 , F02D19/0649 , F02D19/081 , F02M31/042 , F02M37/0064 , Y02E20/14 , Y02E50/13 , Y02T10/126 , Y02T10/16 , Y02T10/36 , Y02T50/678
摘要： A method of combusting a very low cetane number material comprises injecting said material into a combustion cylinder of a heterogeneous-charge compression-ignition engine and supplying to the cylinder inlet port supplying the chamber combustion air or working fluid at a temperature substantially above ambient for substantially the entire time that the engine is running. Other aspects of the invention provide a compression ignition engine for use in the method, and method of using the engine to combust fuels.
摘要翻译：燃烧非常低的十六烷值材料的方法包括将所述材料注入异质充电压缩点火发动机的燃烧气缸中，并将其供给到在大体上高于环境温度的温度下供应室燃烧空气或工作流体的气缸入口，整个发动机运行的时间。本发明的其它方面提供了一种用于该方法的压燃式发动机，以及使用该发动机燃烧燃料的方法。

60. 发明授权

US07321828B2 System of components for preparing oligonucleotides 失效
标题翻译：制备寡核苷酸的组分体系
公开(公告)号：US07321828B2
公开(公告)日：2008-01-22
申请号：US09067638
申请日：1998-04-28
申请人： Lex M. Cowsert , Brenda F. Baker , John McNeil , Susan M. Freier , Henri M. Sasmor , Douglas G. Brooks , Cara Ohashi , Jacqueline R. Wyatt , Alexander H. Borchers , Timothy A. Vickers
发明人： Lex M. Cowsert , Brenda F. Baker , John McNeil , Susan M. Freier , Henri M. Sasmor , Douglas G. Brooks , Cara Ohashi , Jacqueline R. Wyatt , Alexander H. Borchers , Timothy A. Vickers
IPC分类号： C12P19/34 , G06F19/00 , C12Q1/68
CPC分类号： C12Q1/6811 , B01J2219/007 , C12N15/1048 , C40B50/02 , G06F19/18 , G06F19/22
摘要： Interative, preferably computer based iterative processes for generating synthetic compounds with desired physical, chemical and/or bioactive properties, i.e., active compounds, are provided. During iterations of the processes, a target nucleic acid sequence is provided or selected, and a library of candidate nucleobase sequences is generated in silico according to defined criteria. A “virtual” oligonucleotide chemistry is chosen and a library of virtual oligonucleotide compounds having the selected nucleobase sequences is generated. These virtual compounds are reviewed and compounds predicted to have particular properties are selected. The selected compounds are robotically synthesized and are preferably robotically assayed for a desired physical, chemical or biological activity. Active compounds are thus generated and, at the same time, preferred sequences and regions of the target nucleic acid that are amenable to oligonucleotide or sequence-based modulation are identified.
摘要翻译：提供了用于产生具有期望的物理，化学和/或生物活性的合成化合物（即活性化合物）的相互优选的基于计算机的迭代方法。在该过程的迭代过程中，提供或选择靶核酸序列，并且根据确定的标准以计算机生成候选核碱基序列的文库。选择“虚拟”寡核苷酸化学，并产生具有选定的核碱基序列的虚拟寡核苷酸化合物文库。审查这些虚拟化合物，并选择预测具有特定性质的化合物。所选择的化合物是机械合成的，并且优选机械地测定所需的物理，化学或生物活性。因此产生活性化合物，并且同时确定适用于寡核苷酸或基于序列的调节的靶核酸的优选序列和区域。

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