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51. 发明授权

US09101503B2 Apparatus having variable strut length and methods of use 有权
标题翻译：具有可变支柱长度和使用方法的装置
公开(公告)号：US09101503B2
公开(公告)日：2015-08-11
申请号：US12043513
申请日：2008-03-06
申请人： David Lowe , Craig Bonsignore , David W. Snow , Timothy Robinson , Joshua P. Wiesman , Dawn Henderson , Nathan Maier
发明人： David Lowe , Craig Bonsignore , David W. Snow , Timothy Robinson , Joshua P. Wiesman , Dawn Henderson , Nathan Maier
IPC分类号： A61F2/06 , A61F2/915 , A61F2/91 , A61F2/966 , A61F2/89
CPC分类号： A61F2/915 , A61F2/89 , A61F2/91 , A61F2/966 , A61F2002/91508 , A61F2002/91533 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558
摘要： A tubular prosthesis has a plurality of tubular rings that are radially expandable from a contracted configuration to an expanded configuration. Each ring comprises a plurality of axially oriented struts that are interconnected so as to form a circumferential series of at least one high peak and at least one low peak. The high and low peaks have apices that are oriented in the same axial direction. The apices of the high and low peaks are also oriented in the same direction and the apices of the high peaks are axially offset from the apices of the low peaks. A bridge member couples a pair of adjacent tubular rings together. The bridge member has a first end connected to a first low peak in a first tubular ring and a second end connected to either a high or low peak in an adjacent tubular ring.
摘要翻译：管状假体具有多个管状环，其从收缩构型可扩展至扩张构型。每个环包括多个轴向取向的支柱，其互连以形成至少一个高峰值和至少一个低峰值的圆周系列。高低峰具有相同轴向取向的顶点。高峰和低峰的顶点也定向在相同的方向，并且高峰的顶点从低峰的顶点轴向偏移。桥构件将一对相邻的管状环连接在一起。桥构件具有连接到第一管状环中的第一低峰的第一端和连接到相邻管状环中的高峰或低峰的第二端。

52. 发明授权

US08806055B2 System and method for stream processing utilizing totipotent morphogenic stem cells 有权
标题翻译：使用全能形态干细胞的流处理系统和方法
公开(公告)号：US08806055B2
公开(公告)日：2014-08-12
申请号：US13212514
申请日：2011-08-18
申请人： Kenneth Sabir , David Lowe
发明人： Kenneth Sabir , David Lowe
IPC分类号： G06F15/16
CPC分类号： H04L69/40 , H04L67/1002 , H04W4/70
摘要： A method, computer program product, and system for de-centralized stream processing is provided. The method may include providing a plurality of processing nodes each of said processing nodes configured to transmit and receive a stream of data. The method may further include restricting a subset of the plurality of processing nodes from differentiating into a role. The method may also include identifying a failure at one of the processing nodes and replacing the failed node with one of the processing nodes from the restricted subset.
摘要翻译：提供了一种用于去集中式流处理的方法，计算机程序产品和系统。该方法可以包括提供多个处理节点，每个处理节点被配置成发送和接收数据流。该方法还可以包括将多个处理节点的子集限制为一个角色。该方法还可以包括在处理节点之一处识别出故障，并且从受限子集中用处理节点之一替换故障节点。

53. 发明授权

US08801861B2 Cleaning apparatus with brush head disengager 有权
标题翻译：带刷头分离器的清洁装置
公开(公告)号：US08801861B2
公开(公告)日：2014-08-12
申请号：US13499819
申请日：2010-10-06
申请人： Aaron D. Cobabe , W. Kenneth Thiess , David Lowe , David O. Meyers
发明人： Aaron D. Cobabe , W. Kenneth Thiess , David Lowe , David O. Meyers
IPC分类号： B08B1/04 , A46B13/02 , B08B1/00 , A46B13/00
CPC分类号： B08B1/002 , A46B13/008 , A46B13/02 , A46B2200/3033 , A47L13/10 , A47L25/00 , B08B1/04
摘要： A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A hub having a rotational axis about which the hub rotates is coupled with the drive shaft such that rotation of the drive shaft facilitates rotation of the hub. A cleaning head is removably coupled with the hub such that rotation of the hub causes rotation of the cleaning head. A disengaging system is movable between a first position where the cleaning head is securely engaged to the hub and a second position where the cleaning head is freely removable from the hub.
摘要翻译：清洁设备包括细长的壳体，其围绕设置在其中的电动机的一个室。驱动轴至少部分地设置在壳体的腔室内，驱动轴与马达联接，使得在马达的选择性操作期间驱动轴旋转。具有轮毂旋转的旋转轴线的毂与驱动轴联接，使得驱动轴的旋转有助于轮毂的旋转。清洁头可拆卸地与轮毂联接，使得毂的旋转引起清洁头的旋转。分离系统可以在清洁头牢固地接合到轮毂的第一位置和清洁头可自由地从轮毂移除的第二位置之间移动。

54. 发明授权

US08473355B2 System and method for electronic wallet conversion 有权
标题翻译：电子钱包转换系统和方法
公开(公告)号：US08473355B2
公开(公告)日：2013-06-25
申请号：US10690145
申请日：2003-10-20
申请人： Benjamin Quigley , Robert Sandler , Fletcher Jones , Rajesh Mahajan , Prakash Muppirala , David Lowe , Laura Price , Seth Goldstein , Venkatesh Subramanya , Jai Rawat
发明人： Benjamin Quigley , Robert Sandler , Fletcher Jones , Rajesh Mahajan , Prakash Muppirala , David Lowe , Laura Price , Seth Goldstein , Venkatesh Subramanya , Jai Rawat
IPC分类号： G06Q30/00
CPC分类号： G06Q20/36 , G06Q20/105 , G06Q20/206 , G06Q20/363 , G06Q20/40 , G07F7/0866 , G07F7/1008 , G07F7/1025
摘要： A system and method for electronic wallet conversion allows conversion of a basic electronic wallet to a more flexible wallet account, providing additional services and requiring additional authentication. The basic accountholder eventually requires the additional services provided by the more flexible wallet, typically editing rights and making purchases at sites requiring authentication beyond the basic level. To convert the account, the account holder is presented with a one-time challenge and response mechanism that requires the accountholder to summon information that only the account holder would know. If a successful match is made, the account is converted to the more flexible account for all time. The accountholder replaces the one-time challenge and response with a second-level password that grants the accountholder ongoing access to more sensitive wallet features, such as the ability to purchase at sites requiring a second-level password, and editing rights to the information stored in the wallet.
摘要翻译：用于电子钱包转换的系统和方法允许将基本电子钱包转换为更灵活的钱包帐户，提供附加服务并需要额外的认证。基本的帐户持有人最终需要更灵活的钱包提供的附加服务，通常是修改权利，并在需要超出基本级别认证的站点进行购买。要转换帐户，帐户持有人将获得一次性的挑战和响应机制，要求帐户持有人召集只有帐户持有人知道的信息。如果成功匹配，该帐户将被转换为更灵活的账户。帐户负责人用一个二级密码替代一次性的挑战和响应，该密码授权帐户持续访问更敏感的钱包功能，例如在需要二级密码的站点上购买的能力，以及编辑存储的信息的权限在钱包里

55. 发明申请

US20130046903A1 SYSTEM AND METHOD FOR STREAM PROCESSING UTILIZING TOTIPOTENT MORPHOGENIC STEM CELLS 有权
标题翻译：用于流行多发性干细胞的流程处理的系统和方法
公开(公告)号：US20130046903A1
公开(公告)日：2013-02-21
申请号：US13212514
申请日：2011-08-18
申请人： Kenneth Sabir , David Lowe
发明人： Kenneth Sabir , David Lowe
IPC分类号： G06F15/16
CPC分类号： H04L69/40 , H04L67/1002 , H04W4/70
摘要： A method, computer program product, and system for de-centralized stream processing is provided. The method may include providing a plurality of processing nodes each of said processing nodes configured to transmit and receive a stream of data. The method may further include restricting a subset of the plurality of processing nodes from differentiating into a role. The method may also include identifying a failure at one of the processing nodes and replacing the failed node with one of the processing nodes from the restricted subset.
摘要翻译：提供了一种用于去集中式流处理的方法，计算机程序产品和系统。该方法可以包括提供多个处理节点，每个处理节点被配置成发送和接收数据流。该方法还可以包括将多个处理节点的子集限制为一个角色。该方法还可以包括在处理节点之一处识别出故障，并且从受限子集中用处理节点之一替换故障节点。

56. 发明申请

US20130046901A1 SYSTEM AND METHOD FOR STREAM PROCESSING 有权
标题翻译：用于流程处理的系统和方法
公开(公告)号：US20130046901A1
公开(公告)日：2013-02-21
申请号：US13212330
申请日：2011-08-18
申请人： Kenneth Sabir , David Lowe
发明人： Kenneth Sabir , David Lowe
IPC分类号： G06F15/16
CPC分类号： H04L67/1002 , H04W4/70
摘要： A method, computer program product, and system for de-centralized stream processing is provided. The method may include providing a plurality of processing nodes each of said processing nodes configured to transmit and receive a stream of data. The method may further include adding one or more new processing nodes to the computing system. The method may also include determining a source node based upon, at least in part, an activation level being above or below a particular threshold. The method may additionally include, for each of the one or more added processing nodes, automatically determining an appropriate role, based upon, at least in part, a neighboring processing node.
摘要翻译：提供了一种用于去集中式流处理的方法，计算机程序产品和系统。该方法可以包括提供多个处理节点，每个处理节点被配置成发送和接收数据流。该方法还可以包括向计算系统添加一个或多个新的处理节点。该方法还可以包括至少部分地基于高于或低于特定阈值的激活水平来确定源节点。该方法可以另外包括对于一个或多个添加的处理节点中的每一个，至少部分地基于相邻处理节点来自动确定适当的角色。

57. 发明授权

US07985249B2 Endoprosthesis having foot extensions 有权
标题翻译：具有脚伸展的内假体
公开(公告)号：US07985249B2
公开(公告)日：2011-07-26
申请号：US11358279
申请日：2006-02-21
申请人： David Lowe , Erik Eli , Jeff Pappas , Howard H. Huang , Anton G. Clifford , Kevin Kang
发明人： David Lowe , Erik Eli , Jeff Pappas , Howard H. Huang , Anton G. Clifford , Kevin Kang
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2210/0076 , A61F2230/0043 , A61F2230/0054
摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.
摘要翻译：内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个挠曲区域。第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。环形元件通常在输送配置和展开配置之间可扩展。环形元件在连接位置处纵向对齐并连接。优选地，每个连接位置包括脚部延伸部，例如通过在纵向相邻的环形元件之间的重叠图案，或者通过在它们之间延伸的连接器。

58. 发明申请

US20100312329A1 ENDOPROSTHESIS HAVING FOOT EXTENSIONS 审中-公开
标题翻译：具有足迹延伸的内吞
公开(公告)号：US20100312329A1
公开(公告)日：2010-12-09
申请号：US12840858
申请日：2010-07-21
申请人： David Lowe , Erik Eli , Jeff Pappas , Howard H. Huang , Anton G. Clifford , Kevin Kang
发明人： David Lowe , Erik Eli , Jeff Pappas , Howard H. Huang , Anton G. Clifford , Kevin Kang
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2210/0076 , A61F2230/0043 , A61F2230/0054
摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.
摘要翻译：内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个弯曲区域。第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。环形元件通常在输送配置和展开配置之间可扩展。环形元件在连接位置处纵向对齐并连接。优选地，每个连接位置包括脚部延伸部，例如通过在纵向相邻的环形元件之间的重叠图案，或者通过在它们之间延伸的连接器。

59. 发明授权

US07625398B2 Endoprosthesis having foot extensions 有权
公开(公告)号：US07625398B2
公开(公告)日：2009-12-01
申请号：US10992976
申请日：2004-11-19
申请人： Anton Clifford , Kevin Kang , David Lowe , Jeff Pappas , Erik Eli , Howard Huang , Lisa Weldon , Ketan Muni , Eugene Young
发明人： Anton Clifford , Kevin Kang , David Lowe , Jeff Pappas , Erik Eli , Howard Huang , Lisa Weldon , Ketan Muni , Eugene Young
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2230/0054 , A61F2250/0098 , Y10T29/49826 , Y10T29/49908
摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.

60. 发明申请

US20070298034A9 SULFOTYROSINE SPECIFIC ANTIBODIES AND USES THEREFOR 审中-公开
公开(公告)号：US20070298034A9
公开(公告)日：2007-12-27
申请号：US11608564
申请日：2006-12-08
申请人： Angela Widom , Kimberly Marquette , Gray Shaw , Louise Conroy , David Lowe
发明人： Angela Widom , Kimberly Marquette , Gray Shaw , Louise Conroy , David Lowe
IPC分类号： A61K39/395 , G01N33/53 , C07H21/04 , C12P21/06 , C12N5/06 , C07K16/18
CPC分类号： C07K16/44 , A61K2039/505 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/622 , G01N33/6815 , G01N33/6842 , G01N2500/02
摘要： This application relates to sulfotyrosine specific antibodies that are capable of binding selectively to sulfated tyrosine (sulfotyrosine), as well as their production and use. In certain embodiments, the antibodies distinguish sulfated tyrosine containing proteins from phosphorylated tyrosine containing proteins. Methods to detect or quantitate the presence of sulfotyrosine and/or sulfotyrosine containing protein in a biological sample, by adding a sulfotyrosine specific antibody to the sample are provided. Methods to treat systemic inflammatory response syndrome and sepsis by the administration of a sulfotyrosine specific antibody are also provided.

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