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51. 发明授权

US06482631B1 Polynucleotides encoding indole-3-gylcerol phosphate synthase from soybean 失效
标题翻译：从大豆中编码吲哚-3-甲酰磷酸合成酶的多核苷酸
公开(公告)号：US06482631B1
公开(公告)日：2002-11-19
申请号：US09647224
申请日：2001-07-16
申请人： William D. Hitz , Carl A. Maxwell , Yong Tao
发明人： William D. Hitz , Carl A. Maxwell , Yong Tao
IPC分类号： C12N988
CPC分类号： C12N9/1077 , C12N9/88 , C12N15/8251 , C12N15/8254 , C12P13/227
摘要： This invention related to an isolated nucleic acid fragment encoding a tryptophan biosynthetic enzyme. This invention also related to the construction of a Chimeric gene encoding all or a portion of the tryptophan biosynthetic enzyme, in sense or antisense orientation, wherein expression of the Chimeric gene results in the production of altered levels of the tryptophan biosynthetic enzyme in a transformed host cell. The tryptophan biosynthetic enzymes include anthranilate phosphoribosyltransferase (E.C. 2.4.2.18) from corn (Zea mays), soybean (Glycine max) and wheat (Triticum aestivum); indole-3-glycerol phosphate synthase (E.C. 4.1.1.48) from corn (Zea mays), rice (Oryza sativa), soybean (Glycine max), and wheat (Triticum aestivum); and phosphoribosylanthranilate isomerase (E.C. 5.3.1.24) from corn (Zea mays), rice (Oryza sativa), (and wheat (Triticum aestivum).
摘要翻译：本发明涉及编码色氨酸生物合成酶的分离的核酸片段。本发明还涉及在正义或反义方向上构建编码全部或部分色氨酸生物合成酶的嵌合基因，其中嵌合基因的表达导致转化宿主中色氨酸生物合成酶水平的改变细胞。色氨酸生物合成酶包括来自玉米（Zea mays），大豆（Glycine max）和小麦（Triticum aestivum）的邻氨基苯甲酸磷酸核糖基转移酶（E.C.2.4.2.18）; 玉米（Zea mays），水稻（Oryza sativa），大豆（Glycine max）和小麦（Triticum aestivum）的吲哚-3-甘油磷酸合成酶（E.C.4.1.1.48）; 和玉米（Zea mays），水稻（Oryza sativa）（和小麦（Triticum aestivum））的磷酸核糖基邻氨基苯甲酸异构酶（E.C.5.3.1.24）。

52. 发明授权

US06441278B1 Canola oil having increased oleic acid and decreased linolenic acid content 有权
标题翻译：油菜油具有油酸增加和亚麻酸含量降低
公开(公告)号：US06441278B1
公开(公告)日：2002-08-27
申请号：US09482287
申请日：2000-01-13
申请人： Lorin R. DeBonte , William D. Hitz
发明人： Lorin R. DeBonte , William D. Hitz
IPC分类号： A01H500
CPC分类号： C12N9/0083 , A01H5/10 , A23D9/00 , C11B1/10 , C12N15/8218 , C12N15/8247
摘要： An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% &agr;-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.
摘要翻译：公开了从芸苔属种子提取的内源性油，其在破碎和萃取后含有大于86％的油酸和小于2.5％的α-亚麻酸。该油还含有少于7％的亚油酸。芸苔属种子由含有微粒体油酸去饱和酶和微粒体亚油酸去饱和酶基因表达的种子特异性抑制的植物产生。这种抑制可以通过共抑制或反义技术产生。在没有添加抗氧化剂的情况下，这种油具有非常高的氧化稳定性。

53. 发明授权

US06242256B1 Ornithine biosynthesis enzymes 有权
标题翻译：鸟氨酸生物合成酶
公开(公告)号：US06242256B1
公开(公告)日：2001-06-05
申请号：US09347798
申请日：1999-07-02
申请人： Edgar B. Cahoon , Rebecca E. Cahoon , William D. Hitz , J. Antoni Rafalski
发明人： Edgar B. Cahoon , Rebecca E. Cahoon , William D. Hitz , J. Antoni Rafalski
IPC分类号： C12N510
CPC分类号： C12N9/0008 , C12N9/1029 , C12N9/1217 , C12N15/8251
摘要： This invention relates to an isolated nucleic acid fragment encoding an ornithine biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the ornithine biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the ornithine biosynthetic enzyme in a transformed host cell.
摘要翻译：本发明涉及编码鸟氨酸生物合成酶的分离的核酸片段。本发明还涉及在正义或反义方向上编码全部或部分鸟氨酸生物合成酶的嵌合基因的构建，其中嵌合基因的表达导致在转化的宿主细胞中产生改变的鸟氨酸生物合成酶水平。

54. 发明申请

US20120329114A1 XYLOSE UTILIZING ZYMOMONAS MOBILIS WITH IMPROVED ETHANOL PRODUCTION IN BIOMASS HYDROLYSATE MEDIUM 有权
标题翻译：使用生物质水解产物中改善乙醇生产的ZYMOMONAS MOBILIS的XYLOSE
公开(公告)号：US20120329114A1
公开(公告)日：2012-12-27
申请号：US13316597
申请日：2011-12-12
申请人： Perry G. Caimi , William D. Hitz
发明人： Perry G. Caimi , William D. Hitz
IPC分类号： C12N1/21 , C07K14/195 , C12P7/06 , C12N15/31 , C12N15/74
CPC分类号： C12N15/74 , C12N1/20 , C12P7/065 , C12P7/10 , Y02E50/16 , Y02E50/17
摘要： Xylose-utilizing, ethanol producing strains of Zymomonas mobilis with improved performance in medium comprising biomass hydrolysate were isolated using an adaptation process. Independently isolated strains were found to have independent mutations in the same coding region. Mutation in this coding may be engineered to confer the improved phenotype.
摘要翻译：使用适应过程分离具有改善在包含生物质水解产物的培养基中的运动发酵单胞菌发酵单胞菌的乙醇生产菌株。发现独立分离的菌株在相同的编码区域中具有独立的突变。可以将该编码中的突变设计为赋予改良的表型。

55. 发明申请

US20120264822A1 METHOD OF IMPROVING ANIMAL TISSUE QUALITY BY SUPPLEMENTING THE ANIMAL DIET WITH OLEIC ACID AND SELECTED TOCOLS 失效
标题翻译：通过用油酸和选择性的植物油补充动物饮料来改善动物组织质量的方法
公开(公告)号：US20120264822A1
公开(公告)日：2012-10-18
申请号：US13536226
申请日：2012-06-28
申请人： William D. Hitz , Thomas E. Sauber , Court Saunders , Fred R. Wolf
发明人： William D. Hitz , Thomas E. Sauber , Court Saunders , Fred R. Wolf
IPC分类号： A61K31/355 , A61P21/00
CPC分类号： A61K31/202 , A23K20/111 , A23K20/158 , A23K20/174 , A23K50/10 , A23K50/30 , A23K50/75
摘要： A novel method for improving the meat quality of an animal is provided. The method comprises feeding the animal a diet supplemented with oleic acid and selected tocols in amounts effective to improve the meat quality. The method may be practiced on non-ruminants and ruminants.
摘要翻译：提供了一种改善动物肉质的新方法。该方法包括以足以提高肉质的量给动物喂食补充有油酸的食物和选定的奶制品。该方法可以在非反刍动物和反刍动物上实施。

56. 发明申请

US20100043098A1 PLANT RAFFINOSE SACCHARIDE BIOSYNTHETIC ENZYMES 有权
标题翻译：植物萝卜素SACCHARIDE BIOSYNEE ENZYMES
公开(公告)号：US20100043098A1
公开(公告)日：2010-02-18
申请号：US12579720
申请日：2009-10-15
申请人： STEPHEN M. ALLEN , William D. Hitz
发明人： STEPHEN M. ALLEN , William D. Hitz
IPC分类号： A01H5/00 , C12N15/82 , C07H21/04 , C12N15/63 , C12N5/10
CPC分类号： C12N9/1051 , C07H21/04 , C12N15/8245 , C12N15/8246
摘要： This invention relates to an isolated nucleic acid fragment encoding a galactinol synthase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the galactinol synthase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the galactinol synthase in a transformed host cell.
摘要翻译：本发明涉及编码半乳聚糖合酶的分离的核酸片段。本发明还涉及在正义或反义方向上构建编码全部或部分半乳聚糖合酶的嵌合基因，其中嵌合基因的表达导致转化的宿主细胞中肌醇聚糖合酶水平的改变。

57. 发明授权

US07495149B2 Limnanthes oil genes 失效
标题翻译： Limnanthes油基因
公开(公告)号：US07495149B2
公开(公告)日：2009-02-24
申请号：US10855854
申请日：2004-05-27
申请人： Edgar B. Cahoon , William D. Hitz
发明人： Edgar B. Cahoon , William D. Hitz
IPC分类号： A01H5/00 , C12N15/82
CPC分类号： C07H21/04 , C12N9/0083 , C12N9/1029 , C12N15/8247
摘要： This invention relates to an isolated nucleic acid fragment encoding an enzyme involved in lipid biosynthesis. The invention also relates to the construction of a chimeric gene encoding all or a portion of the enzyme involved in lipid biosynthesis, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the enzyme involved in lipid biosynthesis in a transformed host cell.
摘要翻译：本发明涉及编码参与脂质生物合成的酶的分离的核酸片段。本发明还涉及在正义或反义方向上编码参与脂质生物合成的全部或部分酶的嵌合基因的构建，其中嵌合基因的表达导致生产参与脂质生物合成的酶水平的变化转化的宿主细胞。

58. 发明授权

US07217863B2 Mevalonate synthesis enzymes 失效
标题翻译：甲羟戊酸合成酶
公开(公告)号：US07217863B2
公开(公告)日：2007-05-15
申请号：US11062007
申请日：2005-02-18
申请人： Omolayo O. Famodu , William D. Hitz
发明人： Omolayo O. Famodu , William D. Hitz
IPC分类号： A01H1/00 , C07H21/04 , C07K14/415 , C12N5/14 , C12N9/00
CPC分类号： C12N9/88 , C12N9/1029
摘要： This invention relates to an isolated nucleic acid fragment encoding a mevalonate synthesis enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the mevalonate synthesis enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the mevalonate synthesis enzyme in a transformed host cell.
摘要翻译：本发明涉及编码甲羟戊酸合成酶的分离的核酸片段。本发明还涉及在正义或反义方向上编码全部或部分甲羟戊酸合成酶的嵌合基因的构建，其中嵌合基因的表达导致转化的宿主细胞中甲羟戊酸合成酶水平的改变。

59. 发明授权

US06911331B2 Chorismate biosynthesis enzymes 失效
标题翻译： Chorismate生物合成酶
公开(公告)号：US06911331B2
公开(公告)日：2005-06-28
申请号：US10105729
申请日：2002-03-22
申请人： Omolayo O. Famodu , William D. Hitz , Jonathan E. Lightner
发明人： Omolayo O. Famodu , William D. Hitz , Jonathan E. Lightner
IPC分类号： C12N9/88 , C12N15/82 , C12P21/06 , C07H21/04 , C12N1/20 , C12N9/00 , C12N15/00
CPC分类号： C12N9/88 , C12N15/8251 , C12N15/8254
摘要： This invention relates to an isolated nucleic acid fragment encoding a DAHP synthetase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the DAHP synthetase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the DAHP synthetase in a transformed host cell.
摘要翻译：本发明涉及编码DAHP合成酶的分离的核酸片段。本发明还涉及在正义或反义方向上编码全部或部分DAHP合成酶的嵌合基因的构建，其中嵌合基因的表达导致转化的宿主细胞中DAHP合成酶水平的改变。

60. 发明授权

US6063947A Canola oil having increased oleic acid and decreased linolenic acid content 失效
标题翻译：油菜油具有油酸增加和亚麻酸含量降低
公开(公告)号：US6063947A
公开(公告)日：2000-05-16
申请号：US907608
申请日：1997-08-08
申请人： Lorin R. DeBonte , William D. Hitz
发明人： Lorin R. DeBonte , William D. Hitz
IPC分类号： A01H5/10 , A23D9/00 , C11B1/10 , C12N9/02 , C12N15/82 , C07C57/00
CPC分类号： C12N9/0083 , A01H5/10 , A23D9/00 , C11B1/10 , C12N15/8218 , C12N15/8247
摘要： An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% .alpha.-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.
摘要翻译：公开了从芸苔属种子提取的内源性油，其在破碎和提取后含有大于86％的油酸和小于2.5％的α-亚麻酸。该油还含有少于7％的亚油酸。芸苔属种子由含有微粒体油酸去饱和酶和微粒体亚油酸去饱和酶基因表达的种子特异性抑制的植物产生。这种抑制可以通过共抑制或反义技术产生。在没有添加抗氧化剂的情况下，这种油具有非常高的氧化稳定性。

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