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    • 53. 发明授权
    • Physiological event detection systems and methods
    • 生理事件检测系统和方法
    • US08257271B2
    • 2012-09-04
    • US12776557
    • 2010-05-10
    • Krzysztof Z. SiejkoJohn D. Hatlestad
    • Krzysztof Z. SiejkoJohn D. Hatlestad
    • A61B5/04
    • A61B5/00A61B5/053A61B5/746A61B7/023A61N1/3627A61N1/36514
    • Systems and methods using constant false alarm rate techniques for event detection. One example of an event detection method includes collecting a first distribution of measurements for a first physiological parameter. In another example, the first distribution of measurements includes only non-event measurements. One or more values are determined corresponding to at least a first tail area of the first distribution from at least one measurement of the first physiological parameter toward an end point of the distribution. A threshold is established based on a specified false alarm rate. The one or more values are compared to the threshold. The method includes determining if the measurement is representative of a detected event using the comparison.
    • 用于事件检测的常数误报率技术的系统和方法。 事件检测方法的一个示例包括收集第一生理参数的测量的第一分布。 在另一示例中,测量的第一分布仅包括非事件测量。 从第一生理参数的至少一个测量到分布的终点,确定对应于第一分布的至少第一尾区的一个或多个值。 基于指定的虚警率建立阈值。 将一个或多个值与阈值进行比较。 该方法包括使用比较来确定测量是否表示检测到的事件。
    • 54. 发明授权
    • Sleep state detection
    • 睡眠状态检测
    • US08083682B2
    • 2011-12-27
    • US11458602
    • 2006-07-19
    • Yousufali DalalYachuan PuJohn D. Hatlestad
    • Yousufali DalalYachuan PuJohn D. Hatlestad
    • A61B5/08A61B5/02
    • A61B5/0205A61B5/0816A61B5/4809A61B5/4812A61B5/4818G06F19/00
    • This document discusses, among other things, systems and methods for determining sleep state, such as awake, sleeping, non-REM sleep, or REM sleep. Respiration and heart contractions are monitored. A cardio-respiratory ratio such as beats per breath is computed and used in the sleep state determination. Other information, such as heart rate variability (HRV), posture, and activity level can also be used in the sleep state determination. The sleep state information can be used to qualify or trigger storage of other physiological sensor data, or to permit remote sleep study monitoring of a subject, or to control or adjust one or more monitoring, diagnostic, or therapy algorithms, such as, for example a continuous positive airflow pressure (CPAP) device.
    • 本文件还讨论了用于确定睡眠状态的系统和方法,例如清醒,睡眠,非REM睡眠或REM睡眠。 监测呼吸和心脏收缩。 在睡眠状态确定中计算并使用诸如每次呼吸的心跳呼吸比例。 其他信息,例如心率变异性(HRV),姿势和活动水平也可用于睡眠状态确定。 休眠状态信息可用于限定或触发其他生理传感器数据的存储,或允许对对象进行远程睡眠研究监视,或者控制或调整一个或多个监视,诊断或治疗算法,例如 连续正气流压力(CPAP)装置。
    • 57. 发明授权
    • Thoracic impedance detection with blood resistivity compensation
    • 胸部阻抗检测与血液电阻率补偿
    • US07881781B2
    • 2011-02-01
    • US12628384
    • 2009-12-01
    • Jeffrey E. StahmannJohn D. HatlestadBoyce Moon
    • Jeffrey E. StahmannJohn D. HatlestadBoyce Moon
    • A61B5/00
    • A61B5/053A61N1/3627A61N1/36521
    • This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
    • 本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心律管理装置或其他可植入医疗装置,例如用于检测或预测充血性心力衰竭,肺水肿,胸腔积液,低血压 ,等等。 根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化,这可能是血细胞比容水平的变化或其他因素引起的。 血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。 血液电阻补偿的胸液量也可用于调整心脏起搏,心脏再同步或其他心律控制或对患者的其他治疗。 本文件还讨论了用于预测或指示贫血的装置和方法的应用。
    • 60. 发明授权
    • Physiological event detection systems and methods
    • 生理事件检测系统和方法
    • US07713213B2
    • 2010-05-11
    • US11276735
    • 2006-03-13
    • Krzysztof Z. SiejkoJohn D. Hatlestad
    • Krzysztof Z. SiejkoJohn D. Hatlestad
    • A61B5/02
    • A61B5/00A61B5/053A61B5/746A61B7/023A61N1/3627A61N1/36514
    • Systems and methods using constant false alarm rate techniques for event detection. One example of an event detection method includes collecting a first distribution of measurements for a first physiological parameter. In another example, the first distribution of measurements includes only non-event measurements. One or more values are determined corresponding to at least a first tail area of the first distribution from at least one measurement of the first physiological parameter toward an end point of the distribution. A threshold is established based on a specified false alarm rate. The one or more values are compared to the threshold. The method includes determining if the measurement is representative of a detected event using the comparison.
    • 用于事件检测的常数误报率技术的系统和方法。 事件检测方法的一个示例包括收集第一生理参数的测量的第一分布。 在另一示例中,测量的第一分布仅包括非事件测量。 从第一生理参数的至少一个测量到分布的终点,确定对应于第一分布的至少第一尾区的一个或多个值。 基于指定的虚警率建立阈值。 将一个或多个值与阈值进行比较。 该方法包括使用比较来确定测量是否表示检测到的事件。