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51. 发明申请

US20100311641A1 PEPTIDE-BASED BODY SURFACE COLORING REAGENTS 审中-公开
标题翻译：基于肽的身体表面色素试剂
公开(公告)号：US20100311641A1
公开(公告)日：2010-12-09
申请号：US12837525
申请日：2010-07-16
申请人： JOHN P. O'BRIEN , Hong Wang , Ying Wu
发明人： JOHN P. O'BRIEN , Hong Wang , Ying Wu
IPC分类号： A61K38/02 , C07K2/00 , C07K7/00 , C07K14/00 , A61Q11/00 , A61P31/00
CPC分类号： A61K8/64 , A61K2800/43 , A61K2800/57 , A61K2800/94 , A61Q3/00 , A61Q5/065 , A61Q11/00 , A61Q19/04
摘要： Peptides have been identified that bind with high affinity to body surfaces, such as, hair, skin, nails, teeth, gums, and oral cavity surfaces. Peptide-based body surface coloring reagents, preferably tooth coloring reagents, are formed by coupling a tooth binding peptide to a pigment binding peptide, either directly or through a spacer. The peptide-based body coloring reagents may be used in conjunction with pigments to color body surfaces.
摘要翻译：已经鉴定出已经以高亲和力结合到身体表面，例如头发，皮肤，指甲，牙齿和口腔表面的肽。通过将牙结合肽直接或通过间隔物偶联到颜料结合肽而形成基于肽的体表着色剂，优选牙齿着色剂。基于肽的身体着色剂可以与颜料结合使用以使身体表面着色。

52. 发明授权

US07700716B2 Polytetrafluoroethylene binding peptides and methods of use 有权
标题翻译：聚四氟乙烯结合肽及其使用方法
公开(公告)号：US07700716B2
公开(公告)日：2010-04-20
申请号：US11607734
申请日：2006-12-01
申请人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
发明人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
IPC分类号： C07K7/00 , C07K7/06 , C07K7/08
CPC分类号： C07K14/001 , A61K8/64 , A61K47/58 , A61K47/6957 , A61K2800/57 , A61Q5/065 , A61Q5/12 , C07K7/06 , C07K7/08 , C07K14/4723 , C07K14/4741 , C08L53/00 , C08L53/005 , C08L2666/02 , C09D7/63 , C09D11/03 , C09D153/00 , C09D153/005 , C09J153/00 , C09J153/005 , Y10T156/10
摘要： Combinatorially generated peptides are provided that have binding affinity for Polytetrafluoroethylene (PTFE). The peptides may be used to deliver benefit agents to various PTFE surfaces.
摘要翻译：提供与聚四氟乙烯（PTFE）具有结合亲和力的组合产生的肽。肽可以用于将有益剂递送到各种PTFE表面。

53. 发明授权

US07538187B2 Coloring compositions with peptide-based dispersants and binders 失效
标题翻译：使用基于肽的分散剂和粘合剂的着色组合物
公开(公告)号：US07538187B2
公开(公告)日：2009-05-26
申请号：US11194834
申请日：2005-08-01
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： C07K14/00 , D06P1/00 , C07K7/00
CPC分类号： C07K7/08 , C07K7/06 , C07K14/001
摘要： Coloring compositions comprising peptide-based dispersants and/or binders are provided. The compositions are particularly useful for the coloring or dyeing of substrates such as paper and textile fabrics. The peptide-based dispersant and/or binder compositions are distinguished by the presence of at least one positively charged terminal amino acid on the peptide portion of the composition which enhances binding to the substrate.
摘要翻译：提供了包含基于肽的分散剂和/或粘合剂的着色组合物。所述组合物特别可用于诸如纸和纺织织物的基材的着色或染色。基于肽的分散剂和/或粘合剂组合物的特征在于在组合物的肽部分上存在至少一个带正电荷的末端氨基酸，其增强与底物的结合。

54. 发明申请

US20080175798A1 PEPTIDE-BASED HAIR PROTECTANTS 审中-公开
标题翻译：基于基于肽的护发素
公开(公告)号：US20080175798A1
公开(公告)日：2008-07-24
申请号：US11939583
申请日：2007-11-14
申请人： WILLIAM A. BECK , John P. O'Brien , Hong Wang
发明人： WILLIAM A. BECK , John P. O'Brien , Hong Wang
IPC分类号： A61K8/02 , C07K2/00 , A61K8/64
CPC分类号： A61Q17/04 , A61K8/64 , A61K47/62 , A61K2800/57 , A61K2800/94 , A61Q5/12
摘要： Peptide-based hair protectants, formed by coupling at least one hair-binding peptide with at least one sunscreen agent, are described. The hair-binding peptide portion of the peptide-based hair protectant binds to hair with high affinity, thus keeping the sunscreen agent attached to the hair for long lasting protection. Hair care compositions comprising the peptide-based hair protectants are also described.
摘要翻译：描述了通过将至少一种毛发结合肽与至少一种防晒剂偶联形成的基于肽的护发剂。基于肽的头发保护剂的头发结合肽部分以高亲和力结合头发，从而保持防晒剂附着在头发上以获得长期保护。还描述了包含基于肽的头发保护剂的护发组合物。

55. 发明申请

US20070289471A1 Signal transmission fuse 失效
标题翻译：信号传输保险丝
公开(公告)号：US20070289471A1
公开(公告)日：2007-12-20
申请号：US11452571
申请日：2006-06-14
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： C06C5/00
CPC分类号： C06C5/04
摘要： A small diameter shock tube of unique internal surface configuration such that the powder loading per meter of tubing can be higher than achieved with conventional shock tube. The outside diameter of the tube is less than 0.10″, preferably 0.085″ with inner and outer layers of different polymeric material bonded together in a coextrusion process. The inside surface of the shock tube has radially inwardly projecting ribs or protuberances that result in an increase of the internal perphi of the inner surface cross section achieving a 30% increase so that powder loading per meter of the tube can be kept in a safe range.
摘要翻译：具有独特内表面构造的小直径冲击管，使得每米管道的粉末负载可高于用传统冲击管实现的粉末负荷。管的外径小于0.10“，优选为0.085”，其中不同聚合材料的内层和外层在共挤出方法中结合在一起。冲击管的内表面具有径向向内突出的肋或突起，其导致内表面横截面的内部弯曲增加，达到30％的增加，使得每米管的粉末负载能够保持在安全范围内。

56. 发明授权

US07287489B1 Pet deterrent device 失效
标题翻译：宠物威慑装置
公开(公告)号：US07287489B1
公开(公告)日：2007-10-30
申请号：US10980543
申请日：2004-11-03
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： A01K29/00
CPC分类号： A01K15/02 , A01M29/12
摘要： A pet deterrent device is herein disclosed wherein common household pets may be trained away from the negative habit of chewing on various household items. The pet deterrent device generally comprises an absorbent substrate having a non-toxic, foul tasting substance impregnated therein which is adapted to be easily applied to any household item including electrical power cords, family heirlooms, furniture, and the like. Suitable absorbent substrates include various fabric materials and thermoplastic compositions such as polyurethane. Upon biting a typical household item/pet deterrent device assembly, the pet receives a foul taste thereby providing immediate negative reinforcement and thus training the pet away from the negative chewing behavior.
摘要翻译：本文公开了一种宠物威慑装置，其中可以训练常见的家庭宠物，以避免咀嚼各种家庭用品的消极习惯。宠物威慑装置通常包括具有浸渍在其中的无毒，无味的物质的吸收性基材，其适于容易地应用于任何家用物品，包括电力线，家族传家宝，家具等。合适的吸收性基材包括各种织物材料和热塑性组合物如聚氨酯。在咬住典型的家庭用品/宠物威慑装置组合件时，宠物会收到恶臭，从而提供立即的负强化，从而训练宠物远离负面咀嚼行为。

57. 发明授权

US06272996B1 In-line initiator and firing device assembly 有权
标题翻译：联机启动器和点火装置组装
公开(公告)号：US06272996B1
公开(公告)日：2001-08-14
申请号：US09406889
申请日：1999-09-28
申请人： John P. O'Brien , Stephen W. Bartholomew
发明人： John P. O'Brien , Stephen W. Bartholomew
IPC分类号： C06C506
CPC分类号： C06C5/06 , F42D1/04 , F42D1/043
摘要： An in-line initiator and firing device assembly includes a shock tube assembly. An in-line initiator is provided for initiating a shock wave along the shock tube assembly, and includes an end sleeve having a bore extending between input and output ends. At least a portion of a surface defining the bore toward the output end of the end sleeve is threaded for threadably receiving and forming threads on an outer surface of the input end of the shock tube assembly. A first retaining device is associated with the end sleeve for receiving a shock wave triggering device and securing the triggering device to the input end of the end sleeve. A firing device assembly is activated by a shock wave transmitted through the shock tube assembly. The firing device includes a barrel having a bore extending between input and output ends. The input end of the barrel communicates with the output end of the shock tube assembly and the output end communicates with a firing device. A firing pin piston is movably disposed within the bore of the barrel, and defines a cavity communicating with the input end of the barrel for storing a propellant charge to be initiated by shock waves transmitted from the shock tube assembly. A second retaining device is associated with the barrel for coupling the firing device to the barrel.
摘要翻译：一体式起动器和点火装置组件包括一个冲击管组件。提供了一种串联启动器，用于启动沿着冲击管组件的冲击波，并且包括具有在输入端和输出端之间延伸的孔的端套。限定朝向端套筒的输出端的孔的表面的至少一部分是螺纹的，用于在冲击管组件的输入端的外表面上螺纹接纳和形成螺纹。第一保持装置与端套相关联，用于接收冲击波触发装置并将触发装置固定到端套的输入端。射击装置组件由穿过冲击管组件的冲击波激活。点火装置包括具有在输入端和输出端之间延伸的孔的桶。筒的输入端与冲击管组件的输出端连通，输出端与击发装置连通。击发销活塞可移动地设置在筒的孔内，并且限定与桶的输入端连通的空腔，用于存储由冲击管组件传递的冲击波引发的推进剂装料。第二保持装置与筒相关联，用于将击发装置联接到枪管。

58. 发明授权

US5935073A Equipment and method for calibration and quality assurance of an ultrasonic bone analysis apparatus 失效
标题翻译：超声骨分析仪器的校准和质量保证的设备和方法
公开(公告)号：US5935073A
公开(公告)日：1999-08-10
申请号：US866804
申请日：1997-05-30
申请人： Kevin E. Wilson , Donald Barry , Dennis G. Lamser , John P. O'Brien , Jay A. Stein
发明人： Kevin E. Wilson , Donald Barry , Dennis G. Lamser , John P. O'Brien , Jay A. Stein
IPC分类号： A61B8/00 , A61B5/107 , A61B8/08
CPC分类号： A61B5/1074 , A61B8/0875 , A61B8/587
摘要： A method of calibrating an ultrasound bone analysis apparatus having a pair of transducer assemblies. Each transducer assembly has a transducer and a coupling pad, and is movable relative to the other so that a face of each pad can be moved to a position in which they mutually contact and to a position where the faces contact body parts. The method according to the present application includes transmitting an ultrasound signal from one transducer and receiving a signal corresponding to the transmitted ultrasound signal through the other transducer when the transducer assemblies are in the first position and the second position. A time for the ultrasound signal to pass through the body part is determined, and a width of the body part based on positions of the transducers is determined. Then, using the time and width values a speed of sound of the ultrasound signal passing through the body part with squish compensation is calculated.
摘要翻译：一种校准具有一对换能器组件的超声骨分析装置的方法。每个换能器组件具有换能器和耦合垫，并且可相对于另一个移动，使得每个垫的表面可以移动到它们相互接触的位置和面接触身体部分的位置。根据本申请的方法包括当换能器组件处于第一位置和第二位置时，从一个换能器发送超声信号并且通过另一个换能器接收与所发射的超声信号相对应的信号。确定超声信号通过身体部位的时间，并且确定基于换能器的位置的身体部位的宽度。然后，使用时间和宽度值计算通过身体部位的超声信号的声音的压缩补偿。

59. 发明授权

US4164352A Golf swing practice mat 失效
标题翻译：高尔夫挥杆练习垫
公开(公告)号：US4164352A
公开(公告)日：1979-08-14
申请号：US872377
申请日：1978-01-26
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： A63B69/36
CPC分类号： A63B69/3667 , A63B69/3661 , A63B69/3673
摘要： A training mat for golfers includes an area of artificial grass from which a teed golf ball may be driven, and a foot placement area on which the golfer stands. The mat contains diverse marking which enable a golfer to properly position his feet and the golf ball when using the different clubs of a set. A foot supporting wedge may be pivotally mounted on the foot placement area to support the golfer's rear foot.
摘要翻译：用于高尔夫球手的训练垫包括可以驱动球杆高尔夫球的人造草地区域和高尔夫球手站立的脚放置区域。垫子包含多种标记，使高尔夫球手在使用一套不同的球杆时能够正确地定位他的脚和高尔夫球。脚支撑楔可以枢转地安装在脚放置区域上以支撑高尔夫球手的后脚。

60. 发明授权

US4118034A Golfer's stance block 失效
标题翻译：高尔夫球手{3 s stance block
公开(公告)号：US4118034A
公开(公告)日：1978-10-03
申请号：US780271
申请日：1977-03-23
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： A43B5/00 , A43B5/18 , A43C15/09 , A63B69/36 , A63B57/00 , A63B69/30
CPC分类号： A63B69/3673 , A43B1/0054 , A43B5/001 , A43B5/18 , A43C15/09
摘要： Wedge-shaped golf training devices are provided with elements to removably affix the devices to the bottom of a conventional or a modified shoe. Several embodiments of the affixing elements are described, including a dovetail joint-like configuration, a wedge engaging pin mounted in the shoe, and a sole mounted magnetic device.
摘要翻译：楔形高尔夫球训练装置设置有可移除地将装置固定到常规或修改鞋底部的元件。描述了固定元件的几个实施例，包括燕尾关节状构造，安装在鞋中的楔形接合销以及唯一安装的磁性装置。

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