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    • 59. 发明申请
    • Barrier device for ostium of left atrial appendage
    • 用于左心耳口的屏障装置
    • US20030120337A1
    • 2003-06-26
    • US10308032
    • 2002-12-03
    • ATRITECH, INC.
    • Robert A. Van TasselRobert G. Hauser
    • A61F002/06
    • A61B17/12022A61B17/00234A61B17/0057A61B17/12122A61B17/12131A61B17/12136A61B17/12159A61B17/12172A61B17/12186A61B90/06A61B2017/00022A61B2017/00044A61B2017/00243A61B2017/00641A61B2017/1205A61B2090/064A61F2/01A61F2002/018A61F2230/0006A61F2230/0069A61F2230/008
    • A membrane applied to the ostium of an atrial appendage for blocking blood from entering the atrial appendage which can form blood clots therein is disclosed. The membrane also prevents blood clots in the atrial appendage from escaping therefrom and entering the blood stream which can result in a blocked blood vessel, leading to strokes and heart attacks. The membranes are percutaneously installed in patients experiencing atrial fibrillations and other heart conditions where thrombosis may form in the atrial appendages. A variety of means for securing the membranes in place are disclosed. The membranes may be held in place over the ostium of the atrial appendage or fill the inside of the atrial appendage. The means for holding the membranes in place over the ostium of the atrial appendages include prongs, stents, anchors with tethers or springs, disks with tethers or springs, umbrellas, spiral springs filling the atrial appendages, and adhesives. After the membrane is in place a filler substance may be added inside the atrial appendage to reduce the volume, help seal the membrane against the ostium or clot the blood in the atrial appendage. The membranes may have anticoagulants to help prevent thrombosis. The membranes be porous such that endothelial cells cover the membrane presenting a living membrane wall to prevent thrombosis. The membranes may have means to center the membranes over the ostium. Sensors may be attached to the membrane to provide information about the patient.
    • 公开了一种用于阻止血液进入可能在其中形成血块的心房附件的心房附近的膜的膜。 膜还可以防止心耳中的血块从其中逸出并进入可能导致血管阻塞的血流,导致中风和心脏病发作。 膜经皮安装在经历心房颤动和其他心脏病症的患者中,其中血栓形成可能在心房附近形成。 公开了将膜固定到位的各种方法。 膜可以保持在心房附近的位置上,或者填满心房内部。 用于将膜保持在心房附近的位置的手段包括插脚,支架,具有系绳或弹簧的锚杆,具有系绳或弹簧的盘,雨伞,填充心房的螺旋弹簧和粘合剂。 在膜就位之后,可以在心耳内添加填充物质以减小体积,有助于将膜与口腔密封或凝结在心耳中的血液。 膜可以具有抗凝剂以帮助预防血栓形成。 膜是多孔的,使得内皮细胞覆盖呈现活膜膜的膜以防止血栓形成。 膜可以具有使膜在孔上方居中的手段。 传感器可以连接到膜以提供关于患者的信息。
    • 60. 发明授权
    • Intracardiac cage and method of delivering same
    • US10143458B2
    • 2018-12-04
    • US15261311
    • 2016-09-09
    • ATRITECH, INC.
    • Marc S. Kreidler
    • A61B17/00A61B17/12A61F2/01A61F2/24
    • A method of preventing ingress of material into the left atrium of a heart includes providing a delivery sheath, advancing the sheath distal end through an opening between the right atrium and the left atrium of the heart, providing an expandable cage, delivering the expandable cage to the left atrium, and expanding the expandable cage within the left atrium. The expandable cage includes a proximal end, a distal end, and a plurality of supports extending therebetween. The expandable cage also includes a first membrane provided at its proximal end and a second membrane provided at its distal end. The expandable cage has a collapsed configuration so that it can be received within the lumen of the delivery sheath, and an expanded configuration for deployment within the heart. When expanded, the first membrane is positioned at an opening between the left and right atria of the heart, and the second membrane is positioned at the ostium of the left atrial appendage. The first membrane substantially prevents passage of blood between the atria and the second membrane prevents passage of embolic material from the left atrial appendage into the left atrium of the heart.